Abstract：
:Intracerebroventricular (ICV) infusions of 2-deoxy-D-glucose (2-DG) elicited hyperglycemia and increased feeding at short latencies. If access to food was prevented for 6 h post-2-DG infusion, when blood glucose levels were normal and brain 2-DG concentrations were virtually zero, the rats still ate significantly more food than they did 6 h after control infusions. These data indicate that activation of brain glucoreceptors may mediate increased feeding even after other signs of cerebral glucoprivation have disappeared.
journal_name
Brain Resjournal_title
Brain researchauthors
Engeset RM,Ritter RCsubject
Has Abstractpub_date
1980-11-24 00:00:00pages
229-33issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(80)90660-5journal_volume
202pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:The phenomenon of unidirectional non-cross tolerance (UNCT) to etorphine was observed in adult male rats tolerant to morphine. Using a morphine pellet (four 75 mg morphine pellets) implantation protocol, a 10-fold increase in the analgesic ED50 value, obtained by tail-flick assay, was observed for morphine sulfate, wi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91502-1
更新日期：1985-02-18 00:00:00
abstract：:Two distinct serotonin receptors in mammalian brain are labeled respectively with [3H]serotonin (5-HT1) and [3H]spiperone (5-HT2). In general agonists display highest affinities for 5-HT1 while antagonists prefer 5-HT2 sites. To conduct regional studies of 5-HT receptors, we estimated 5-HT2 sites with [3H]spiperone, u...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90562-x
更新日期：1981-03-16 00:00:00
abstract：:Reducing external calcium from 1.0 to 0.1 mM increased the flash sensitivity and the time-to-peak (tp) of linear responses of rod photoreceptors. The quantitative relation between flash sensitivity and tp was the same as during light adaptation. However, the calcium ionophore A23187 reduced sensitivity without affecti...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90405-6
更新日期：1985-04-15 00:00:00
abstract：:Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder associated with premutation alleles of the FMR1 gene that is characterized by progressive action tremor, gait ataxia, and cognitive decline. Recent studies of mitochondrial dysfunction in FXTAS have suggested that iron dysre...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2014.11.058
更新日期：2015-02-19 00:00:00
abstract：:The melanocortin (MC)4 receptor is important for food intake and weight homeostasis as it mediates the orexigenic and anorexigenic effects of the MCs. OLETF (Otsuka-Long-Evans-Tokushima-Fatty) rats are a selective inbred strain of polygenic variant rats which overeat and develop obesity with elevated leptin levels. We...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)02125-3
更新日期：2000-01-03 00:00:00
abstract：:Intracerebroventricular (i.c.v.) infusion of sodium in rats increases cerebrospinal fluid (CSF) [Na], mimicking the effects of a high salt diet in salt-sensitive strains and causing sympathetic hyperactivity and a pressor response that are mediated via both an endogenous brain ouabainlike substance (OLS) and the brain...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.06.056
更新日期：2004-09-24 00:00:00
abstract：:Using a perifusion culture technique, the pattern of vasopressin release from the suprachiasmatic nucleus was studied in vitro under basal and stimulated conditions. Individual rat suprachiasmatic explants released vasopressin in a rhythmic fashion and these rhythms persisted with a circadian period for up to 4 cycles...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90952-8
更新日期：1987-10-06 00:00:00
abstract：:Neuronal activity in the nucleus parabrachialis medialis (NPBM) was examined in unanesthetized, unrestrained cats during each sleep-waking state. Discharge related to the cardiac cycle was assessed by calculating cross-correlation functions between neuronal and cardiac events (using the peak of the EKG 'R' wave as a r...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)90696-4
更新日期：1980-10-20 00:00:00
abstract：:Lamprey retriculospinal neurons show phasic oscillations of their membrane potential during fictive locomotion. This modulation originates from the spinal cord locomotor networks. The aim of the present study was to elucidate the pattern of discharge of the spino-bulbar axons responsible for this modulation. Experimen...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90327-6
更新日期：1992-06-05 00:00:00
abstract：:We assessed the chronological change of the expression of synaptophysin, an integral glycoprotein on the presynaptic vesicles, after a transient cerebral ischemic insult in the rat. The ischemic lesion was consistently localized in the dorsolateral part of the striatum, which was clearly visualized by a depletion of c...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90225-c
更新日期：1993-07-09 00:00:00
abstract：:Effects of iontophoretically applied dopamine were investigated in prefrontal neurons of the monkey which showed activity changes during a visual reaction time task. The task consisted of an initial waiting phase (3.0 s), a warning phase (green lamp, 1.5-3.5 s), a lever-release GO phase (red lamp) and a reward phase. ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90385-9
更新日期：1986-04-23 00:00:00
abstract：:Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by upper and lower motor neuron death with ascending paralysis leading to death. In a transgenic mouse model of ALS (SOD1-G93A) weakness appears at 3 months of age, and because of progressive paralysis leads to death by 5 months. Cyclospo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02012-1
更新日期：2001-03-16 00:00:00
abstract：:Two high molecular weight surface glycoproteins of cerebellar cells which are selectively labeled by lactoperoxidase-catalyzed iodination of monolayer cultures from the developing mouse cerebellum, have been identified and partially characterised. Both molecules, called peak 2 and peak 3 proteins, were the major glyco...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)91197-x
更新日期：1980-01-27 00:00:00
abstract：:Unilateral injections of 6-hydroxydopamine into the lateral hypothalamus or ventral tegmental area that damage extensively the mesotelencephalic dopaminergic projection result in significant hemispheric asymmetries in autoradiographic labeling after [14C]2-deoxy-D-glucose (2DG) administration. The incorporation of thi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)90442-4
更新日期：1980-09-15 00:00:00
abstract：BACKGROUND:It is unclear whether spinal cord stimulation (SCS) at higher frequencies induces further increases in vasodilation and enhances clinical efficacy. OBJECTIVES:This study investigated effects of SCS at both a normal frequency (as used clinically) and two higher frequencies on peripheral vasodilation. METHOD...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.11.072
更新日期：2010-02-08 00:00:00
abstract：:The intermediate, medial part of the hyperstriatum ventrale (IMHV) is an area of the avian forebrain which is essential for two forms of early learning in the domestic chick. We have developed an in vitro slice preparation which contains part of the IMHV and have found that the electrophysiological properties of the a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00361-7
更新日期：1996-07-15 00:00:00
abstract：:Dissimilarity of the electroencephalogram (EEG) between the two hemispheres was characterized by cross-approximate entropy (C-ApEn), an information statistical parameter applicable to nonlinear, aperiodic signals. EEGs were recorded bipolarly with pairs of epidural electrodes in the left and right frontal cortices. Th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03358-9
更新日期：2002-11-01 00:00:00
abstract：:Cardiac arrest-induced cerebral hypoxic injury could induce posthypoxic movement disorders. Here we investigated the effects of memantine, an NMDA receptor channel blocker, on the neurodegeneration occurred in an established rat model of posthypoxic myoclonus. We found that administration of memantine for 7 days signi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.11.076
更新日期：2007-02-16 00:00:00
abstract：:Phenylethanolamine N-methyltransferase (PNMT) activity was measured in adrenal glands and medulla oblongata from 4 inbred rat strains, Fischer 344, Buffalo, Lewis and Sprague-Dawley rats. Adrenal enzyme activity was markedly different among the strains with the highest in Fischer, followed by Sprague-Dawley, Lewis and...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91476-9
更新日期：1986-04-30 00:00:00
abstract：:The substantia nigra pars reticulata (SNr) receives both inhibitory GABAergic and excitatory glutamatergic afferents from diverse origins. Ischemic injury to the striatum and/or the globus pallidus causes delayed transneuronal death of the SNr neurons, in the course of which neuronal disinhibition induced by loss of G...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(96)01052-9
更新日期：1996-12-16 00:00:00
abstract：:Myelin of several Caudata (Urodela) species appears to be unique in the fact that it lacks hydroxycerebrosides and hydroxysulfatides although it contains their non-hydroxy counterparts. Comparison of the nerve conduction velocities in the Urodeles Necturus (salamander) and Notophthalmus (newt) with that in a reptile, ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90831-5
更新日期：1985-10-14 00:00:00
abstract：:We examined the effect of the molarless condition on the dendritic spines of hippocampal pyramidal cells in SAMP8 mice in comparison to its effect on learning ability in a maze test. The molarless condition caused a decrease in the number of the spines of CA1 pyramidal cells only in the aged mice showing a reduced lea...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.07.038
更新日期：2005-09-28 00:00:00
abstract：:The substance P and Met-enkephalin content were measured in the rat lumbar spinal cord after monolateral section of the sciatic nerve. The proximal stump of the lesioned nerve was either ligated, limiting the formation of neuroma, or sutured intraperitoneally, allowing the formation of a very large neuroma. Both types...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91147-3
更新日期：1985-09-09 00:00:00
abstract：:The light and electron microscopic localization of leucine-enkephalin-containing terminals in the facial nucleus of the rat were investigated by means of the peroxidase-antiperoxidase (PAP) immunocytochemical technique. By light microscopy, leucine-enkephalin-like immunoreactive (LEI) terminals were unevenly distribut...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90517-6
更新日期：1983-09-05 00:00:00
abstract：:Nasal and temporal microexplants from the retina of the chicken embryo (E6; White Leghorn) were cultured on a collagen gel in the presence of extract from anterior or posterior E18 optic tectum. After 4 days of incubation maximum neurite lengths were measured as a function of protein concentration (1-500 micrograms/ml...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(87)90085-x
更新日期：1987-01-01 00:00:00
abstract：:Caprine beta-mannosidosis is an inherited lysosomal storage disorder due to a deficiency of beta-mannosidase which cleaves beta-linked mannose residues from the ends of N-asparagine linked oligosaccharides of glycoproteins. Histological and chemical examination has revealed a deficiency of compact myelin in the brains...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90278-u
更新日期：1993-08-20 00:00:00
abstract：:Electrical stimulation of the cerebellar fastigial nucleus (FN) in spontaneously hypertensive (SHR), Wistar-Kyoto (WKY) and Fisher rats reduced, by approximately 50%, the infarctions produced by occlusion of the middle cerebral artery. Blockade of ATP-dependent potassium (K-ATP) channels with glibenclamide (i.c.v.) ab...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01871-5
更新日期：1999-09-25 00:00:00
abstract：:The binding characteristics of [3H]cytisine, a putative CNS nicotinic receptor ligand, were examined in 4 regions of the human brain. [3H]Cytisine was found to bind non-cooperatively with high affinity to a single site in tissue homogenates and to exhibit low non-specific association. The binding characteristics of th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90410-o
更新日期：1993-01-08 00:00:00
abstract：:The effects of ventromedial hypothalamic (VMH) stimulation on various metabolic parameters in freely moving animals were measured using a specific indirect calorimetric chamber associated with a quantitative measurement of locomotor activity, which allows the separate measurement of locomotor energy expenditure from t...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01922-8
更新日期：1999-10-30 00:00:00
abstract：:Choline is an essential nutrient whose availability during the second half of gestation produces long-lasting cognitive effects. Rats that obtain supplemental choline during embryonic day (E) 11-17 have enhanced depolarization-evoked acetylcholine (ACh) release from hippocampal slices, whereas choline deficiency durin...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.08.046
更新日期：2008-10-27 00:00:00
