Abstract:
:Interdigestive migrating contractions (IMC) were analyzed for their occurrence interval, duration, migrating velocity, and frequently in long term records obtained by means of chronically implanted force transducers in the main stomach and the extrinsically denervated fundic pouches or in the intact jejunum and the extrinsically denervated Thirty loop in 10 conscious dogs. Plasma immunoreactive motilin (IRM) was measured simultaneously. It was found that concomitant occurrence of IMC in the main stomach and pouch was closely associated with increase in plasma IRM concentration. On the other hand, in the extrinsically denervated jejunal loop, IMC-like contractions occurred independently of and more frequently than those in the intact jejunum and did not correlate with an increase in IRM concentration. It is concluded that gastric motor activity is under humoral control but in the jejunum, autoregulation by the intrinsic nerve plexus is more predominant than humoral factor(s).
journal_name
Peptidesjournal_title
Peptidesauthors
Itoh Z,Nakaya M,Suzuki Tdoi
10.1016/0196-9781(81)90035-8subject
Has Abstractpub_date
1981-01-01 00:00:00pages
223-8eissn
0196-9781issn
1873-5169pii
0196-9781(81)90035-8journal_volume
2 Suppl 2pub_type
杂志文章相关文献
PEPTIDES文献大全abstract::The present study was designed to detect the change of substance P (SP) in firearm wounds and its relationship with wound healing. Twenty two rabbits were randomly divided into two groups, one with firearm wounds created by steel balls shooting rabbits' thighs and another with stab wounds created by knife. The experim...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(98)00068-0
更新日期:1998-01-01 00:00:00
abstract::This study was designed to investigate the effects of synthetic mouse pancreatic polypeptide (mPP) on feeding and anxiety in mice. The intracerebroventricular (i.c.v.) injection of mPP (0.003-3 nmol) dose-dependently increased food intake. A significant increase was observed 20 min after i.c.v. injection and continued...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(99)00155-2
更新日期:1999-12-01 00:00:00
abstract::Dermorphins are potent opiate-like peptides isolated from the skin of some species of frogs. They are characterized by the presence of a D-amino acid residue, which is crucial for bioactivity. A number of analogues were prepared in order to evaluate the structure-activity relationships. The syntheses were accomplished...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(81)80117-9
更新日期:1981-10-01 00:00:00
abstract::Milk is the best, complete food important for the development and nourishment of a neonate. Except for nutrients, milk contains biologically active opioid peptides derived from beta-casein, named beta-casomorphins (BCMs), which can exert effects in the gastrointestinal tract as well as in the whole body of neonates. T...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2007.08.002
更新日期:2007-10-01 00:00:00
abstract::Previous physiological studies have suggested central roles of brain natriuretic peptide (BNP). However, little information is available about the localization of BNP in the brain. In this study, we determined cDNA sequence encoding the entire coding region of prepro-BNP of Japanese and cynomologus monkeys, and then e...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2006.01.001
更新日期:2006-07-01 00:00:00
abstract::Urocortin (Ucn) 1, 2 and 3 are corticotropin-releasing factor (CRF)-related peptides recently characterized in mammals. Urocortin 1 binds with high affinity to CRF type 1 (CRF1) and type 2 (CRF2) receptors while Ucn 2 and Ucn 3 are selective CRF2 ligands. They also have a distinct pattern of distribution, both in the ...
journal_title:Peptides
pub_type: 杂志文章,评审
doi:10.1016/j.peptides.2004.05.025
更新日期:2004-10-01 00:00:00
abstract::The role of muscarinic receptor subtype(s) in the control of gastric phase III contractions and motilin release was determined in dogs. Pirenzepine (226 nmol/kg/h) shortened the phase III cycle, causing an early increase in plasma motilin concentrations. Both AF-DX116BS and 4-DAMP inhibited the occurrence of spontaneo...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(97)00132-0
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVES:The aim of the present studywas to examine the question of whether the atrial natriuretic peptide (ANP) system is altered by endothelial nitric-oxide synthase (eNOS). METHODS:Male eNOS-deficient mice (eNOS-/-) and wild type control mice (eNOS+/+, C57B1/6J) were used. Blood pressure was measured in anestheti...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2010.04.008
更新日期:2010-07-01 00:00:00
abstract::Previously, calcitonin gene-related peptide (CGRP) decreased food intake when administered ICV but not when administered peripherally to rats. Amylin, which has a close structural homology to CGRP, reduced food intake administered IP at concentrations higher than those previously tested for CGRP. We examined the effec...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(96)00015-0
更新日期:1996-01-01 00:00:00
abstract::We tested the effects of intra-lateral septal infusions of neuropeptide Y (NPY) combined with systemic injections of topiramate in the DRL-72s paradigm and the elevated plus-maze test in male Wistar rats. Intra-lateral septal infusions of desipramine (5.0 microg/microl; P<0.05) or intra-lateral septal infusions of NPY...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2010.03.012
更新日期:2010-06-01 00:00:00
abstract::The Manduca allatotropin (Mas-AT) gene is expressed as at least three mRNA isoforms that differ from each other by alternative splicing. The location at which the alternative exons are included in the mature mRNAs occur within the open reading frame, so that three different propeptides are predicted as translation pro...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(00)00378-8
更新日期:2001-02-01 00:00:00
abstract::Many animal studies show an enhancing effect of vasopressin (VP) on memory, but not all human studies could confirm this finding. This study examined the influence of post-learning administration of VP (40 IU, intranasally) on the consolidation of declarative memories in healthy humans during different intervals of sl...
journal_title:Peptides
pub_type: 临床试验,杂志文章
doi:10.1016/s0196-9781(01)00625-8
更新日期:2002-03-01 00:00:00
abstract::ACTH/MSH(4-10) (10 micrograms/kg/b.i.d.; IP), administered to pregnant Sprague-Dawley rats during gestational days (GD) 3 to 12, significantly increased the metabolic activity of extensor digitorum longus (EDL) muscle at postnatal day 14. ACTH/MSH peptide, administered from day of birth to postnatal day 13, had no eff...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(90)90128-r
更新日期:1990-01-01 00:00:00
abstract::Early-life stress is a key predisposing factor to the development of functional gastrointestinal (GI) disorders. Thus, changes in stress-related molecular substrates which influence colonic function may be important in understanding the pathophysiology of such disorders. Activation of peripheral corticotropin-releasin...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2010.01.004
更新日期:2010-04-01 00:00:00
abstract::The basal caeliferan family Tetrigidae is investigated to identify neuropeptides belonging to the adipokinetic hormone (AKH) family. The pygmy grasshopper Tetrix subulata contains in its corpus cardiacum two octapeptides as revealed by liquid chromatography coupled to electrospray ionization mass spectrometry. The les...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2015.01.008
更新日期:2015-06-01 00:00:00
abstract::The present study purifies two T. serrulatus non-disulfide-bridged peptides (NDBPs), named venom peptides 7.2 (RLRSKG) and 8 (KIWRS) and details their synthesis and biological activity, comparing to the synthetic venom peptide 7.1 (RLRSKGKK), previously identified. The synthetic replicate peptides were subjected to a ...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2016.05.008
更新日期:2016-08-01 00:00:00
abstract::Most small peptide hormones and neurotransmitters are highly flexible, conformationally labile molecules in aqueous and other environments. Thus efforts to determine the relationships between conformational properties of these peptides in aqueous and other solvents and their biological activities at membrane receptors...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(82)90095-x
更新日期:1982-05-01 00:00:00
abstract::We have previously shown that brief, vena caval infusion of gastrin-releasing peptide1-27 (GRP), delivered shortly (5 min) after the end of the first spontaneous nocturnal meal, significantly prolongs the postprandial intermeal interval (IMI) without affecting the size of the subsequent meal in freely-feeding rats. In...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(98)00097-7
更新日期:1998-01-01 00:00:00
abstract::Recent data suggests that neurons expressing the long form of the leptin receptor form at least two distinct groups within the caudal nucleus of the solitary tract (NTS): a group within the lateral NTS (Slt) and one within the medial (Sm) and gelantinosa (Sg) NTS. Discrete injections of leptin into Sm and Sg, a region...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2013.03.021
更新日期:2013-06-01 00:00:00
abstract::The distribution of somatostatin (SRIF) was examined in normal human forebrain, using thick vibratome cut sections. The unlabeled antibody enzyme method of immunocytochemistry revealed a widespread distribution of SRIF immunoreactive neurons and fibers throughout the septum, diencephalon and corpus striatum. Within th...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(86)90109-9
更新日期:1986-09-01 00:00:00
abstract::The peptide IIAEK derived from beta-lactoglobulin has a hypocholesterolemic activity greater than that of beta-sitosterol. To create food proteins with multiple copies of this valuable peptide sequence, we introduced tandem multimers of the nucleotide sequence encoding the peptide into DNA regions corresponding to the...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2005.11.007
更新日期:2006-06-01 00:00:00
abstract::The cDNAs encoding the preprohormones of the regulatory peptides cholecystokinin (CCK) and the related gastrin have been identified in a number of vertebrate species. However, from birds only chicken preprogastrin is known. In the present study preproCCK cDNA was identified in two species of birds, ostrich and chicken...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(00)00276-x
更新日期:2000-09-01 00:00:00
abstract::Studies were conducted in order to determine if selected neurons could be isolated from the brain using Sepharose-linked recognition complexes directed against or related to the biosynthetic/neurosecretory product of the desired neuronal population. Immunoreactive LRF neurons were precipitated when dispersed cells of ...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(85)90061-0
更新日期:1985-03-01 00:00:00
abstract::Amyloid deposition in Alzheimer fibrils forms neurotoxic senile plaques in a process that may be modulated by associated proteins. In this work we demonstrate the ability of laminin-1 and laminin-2 to inhibit fibril formation and toxicity on cultured rat hippocampal neurons. We confirm that the laminin-1-derived pepti...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(02)00058-x
更新日期:2002-07-01 00:00:00
abstract::To confirm and extend the results of previous studies which demonstrated central cardiovascular effects of vasopressin in anesthetized rats, we determined blood pressure and heart rate changes for 30 minutes after intracerebroventricular injections of arginine vasopressin, arginine vasotocin and oxytocin in conscious ...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(83)90008-6
更新日期:1983-09-01 00:00:00
abstract::TRH and PS-24 (a TRH peptidase resistant analogue) induce different effects on body temperature and motor activity in rats kept at 4 degrees C. PS-24 induced hypothermia, but TRH did not. PS-24 induced hypermotility, while TRH induced slight hypomotility. The thermal effect of TRH in hypophysectomized rats was similar...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(81)80024-1
更新日期:1981-07-01 00:00:00
abstract::Gastrin/CCK peptides in extracts from bovine and porcine pituitary have been characterized by Sephadex gel filtration, reverse phase liquid chromatography and a CCK radioimmunoassay (RIA) which detects both CCK and gastrin [4]. Porcine pituitary extracts contain a small amount of two peptides with chromatographic beha...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(82)90121-8
更新日期:1982-05-01 00:00:00
abstract::Due to recent emergence of fungal pathogens resistant to current antifungal therapies, several studies have been focused on screening of plant peptides to find novel compounds having antifungal activities. Here, a novel antifungal plant peptide, with molecular mass of 1230 Da was purified from fruits of Trapa natans b...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2011.06.020
更新日期:2011-08-01 00:00:00
abstract::A peptide designated cicerarin, with an N-terminal amino acid sequence VKSTGRADDDLAVKTKYLPP dissimilar from known proteins and peptides and a molecular mass of 8kDa, was isolated from seeds of the green chickpea Cicer arietinum cv green chickpea. Cicerarin was isolated with a procedure that involved ion exchange chrom...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(03)00134-7
更新日期:2003-05-01 00:00:00
abstract::In the crayfish Astacus leptodactylus, as in several crustacean species, the crustacean hyperglycemic hormone is present as two isoforms differing by the chirality of the third residue, a phenylalanine. In the present work, isoforms synthesized full length by solid-phase peptide synthesis have been purified, refolded,...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2012.01.019
更新日期:2012-03-01 00:00:00