Effects of TRH and PS-24 on colonic temperature and motor activity of rats: possible role of dopamine.

abstract：:The geniculohypothalamic tract (GHT) is a projection from the intergeniculate leaflet to the suprachiasmatic nucleus (SCN). The GHT exhibits neuropeptide Y (NPY) immunoreactivity and appears to communicate photic information to the SCN. Microinjection of NPY into the SCN has been found to phase shift circadian rhythms...

journal_title：Peptides

authors： Huhman KL,Albers HE

更新日期：1994-01-01 00:00:00

abstract：:So far numerous antimicrobial peptides have been characterized from amphibians. In this work, a new family of antimicrobial peptides, named shuchin, was purified and characterized from skin secretions of the frog, Rana shuchinae that lives in freezing mountains. Totally two members of shuchin (shuchin 1 and 2) were id...

journal_title：Peptides

authors： Zheng R,Yao B,Yu H,Wang H,Bian J,Feng F

更新日期：2010-09-01 00:00:00

abstract：:The purpose of this study was to examine the resting and exercise response patterns of plasma Peptide F immunoreactivity (ir) to altitude exposure (4300 m) and caffeine ingestion (4 mg.kg b.w.-1). Nine healthy male subjects performed exercise tests to exhaustion (80-85% VO2max) at sea level (50 m), during an acute alt...

journal_title：Peptides

authors： Kraemer WJ,Rock PB,Fulco CS,Gordon SE,Bonner JP,Cruthirds CD,Marchitelli LJ,Trad L,Cymerman A

更新日期：1988-09-01 00:00:00

abstract：:Although the biological effects of adrenomedullin (AM) and PAMP have been reported extensively in animal studies and from in-vitro experiments, relatively little information is available on responses to the hormone administered to man. This review summarizes data from the few studies carried out in man. In healthy vol...

journal_title：Peptides

authors： Nicholls MG,Lainchbury JG,Lewis LK,McGregor DO,Richards AM,Troughton RW,Yandle TG

更新日期：2001-11-01 00:00:00

abstract：:Somatostatin is reported in a new population of human sweat duct cells. The epithelial content of somatostatin-like immunoreactivity in normal human skin from various sites of the body was investigated using indirect immunofluorescence. With this methodology we found round-to-oval somatostatin-immunoreactive cells sit...

journal_title：Peptides

authors： Johansson O,Hilliges M,Wang L

更新日期：1993-03-01 00:00:00

abstract：:Angiotensin II binding sites were localized and quantified in individual brain nuclei from single rats by incubation of tissue sections with 1 nM 125I-[Sar1]-angiotensin II, [3H]-Ultrofilm autoradiography, computerized microdensitometry and comparison with 125I-standards. High angiotensin II binding was present in the...

journal_title：Peptides

authors： Saavedra JM,Israel A,Plunkett LM,Kurihara M,Shigematsu K,Correa FM

更新日期：1986-07-01 00:00:00

abstract：:The cross-immunoreactivity, topography, and fiber projections of the alpha MSH-immunoreactive specific neurons in the forebrain of the rat appear to be distinctly different from that of the neurons in the hypothalamic arcuate opiocortin system. The cell bodies, immunoreactive only to alpha-MSH, have a specific pattern...

journal_title：Peptides

authors： Piekut DT,Knigge KM

更新日期：1984-11-01 00:00:00

abstract：:We demonstrated the production and release of a peptide structurally identical with porcine and bovine VIP-28 in human neuroblastoma NB-OK-1 cell line. In the cells, VIP-like immunoreactive (IR-VIP) components of 8 K dalton (Kd), 11 Kd, 18 Kd and 30 Kd were also detected and the 8 Kd and 18 Kd components were apparent...

journal_title：Peptides

authors： Hoshino M,Yanaihara C,Ogino K,Iguchi K,Sato H,Suzuki T,Yanaihara N

更新日期：1984-03-01 00:00:00

abstract：:Mussels have diverse groups of cysteine rich, cationic antimicrobial peptides (AMPs) (defensins, mytilins, myticins, and mytimycin) that constitute an important component of their innate immune defence. Despite the identification and characterization of these AMPs in mussels, the underlying genetic mechanisms that mai...

journal_title：Peptides

authors： Padhi A,Verghese B

更新日期：2008-07-01 00:00:00

abstract：:Intracerebroventricular administration of NPY suppresses ethanol intake in selectively bred alcohol-preferring rat lines, but not in rats selectively bred for low ethanol drinking or in unselected Wistar rats, when access to ethanol is limited to 2h/day. However, when rats undergo chronic (24h/day) ethanol drinking (o...

journal_title：Peptides

authors： Badia-Elder NE,Gilpin NW,Stewart RB

更新日期：2007-02-01 00:00:00

abstract：:The effects of atrial natriuretic factor (ANF) on [3H]norepinephrine ([3H]NE) release evoked by a sodium-free medium (SFM) were studied. Experiments were performed in rat adrenal medulla slices incubated in vitro. Results showed that [3H]NE release evoked by the omission of Na+ was decreased by 10 nM ANF. In addition,...

journal_title：Peptides

authors： Vatta MS,Papouchado ML,Bianciotti LG,Fernandez BE

更新日期：1994-01-01 00:00:00

abstract：:The role of neuropeptides in cardiomyopathy-associated heart failure has been garnering more attention. Several neuropeptides--Neuropeptide Y (NPY), vasoactive intestinal peptide (VIP), calcitonin gene related peptide (CGRP), substance P (SP) and their receptors have been studied in the various types of cardiomyopathi...

journal_title：Peptides

authors： Dvorakova MC,Kruzliak P,Rabkin SW

更新日期：2014-11-01 00:00:00

abstract：:This study determined the long-term influence of prenatal nicotine exposure (PN) on blood pressure and vascular functions in the aged offspring rats. PN did not affect body weight and plasma adrenocorticotropic hormone level; however, it significantly reduced plasma angiotensin I and angiotensin II in both sexes. Syst...

journal_title：Peptides

authors： Tao H,Rui C,Zheng J,Tang J,Wu L,Shi A,Chen N,He R,Wu C,Li J,Yin X,Zhang P,Zhu Z,Tao J,Xiao J,Mao C,Xu Z

更新日期：2013-06-01 00:00:00

abstract：:Arginine vasopressin (AVP), which is synthesized and secreted in the hypothalamic paraventricular nucleus (PVN), is the most important bioactive substance in the pain modulation. Our pervious study had shown that AVP plays an important role in pain modulation in caudate nucleus (CdN). The experiment was designed to in...

journal_title：Peptides

authors： Yang J,Li P,Zhang XY,Zhang J,Hao F,Pan YJ,Lu GZ,Lu L,Wang DX,Wang G,Yan FL

更新日期：2011-01-01 00:00:00

abstract：:In vitro pepsin treatment of plasma proteins generates biologically active peptides such as enkephalin-related peptides. These peptides were characterized using chromatographic techniques along with a radioimmunoassay procedure involving the use of Leu-enkephalin and Met-enkephalin antisera. Serum albumin is the only ...

journal_title：Peptides

authors： Garreau I,Pejoan C,Bressollier P,Verneuil B,Cucumel K,Cupo A

更新日期：1994-01-01 00:00:00

abstract：:This paper reviews aspects of our research, focusing on the role of the melanocortin system in the central regulation of feeding and energy balance, which was begun in 1997. It describes data from successive physiological studies, concerning the identity of the appetite-regulating melanocortin receptor, melanocortin-4...

journal_title：Peptides

authors： Harrold JA,Williams G

更新日期：2006-02-01 00:00:00

abstract：:Intracerebroventricular injection of NPY inhibits epileptiform seizures and seizure-related "wet dog shakes" (WDS) following electrical stimulation of the dentate gyrus or subiculum. This study examined the effects of NPY on seizures and WDS elicited in hippocampal CA3. Like in the other hippocampal regions, NPY signi...

journal_title：Peptides

authors： Klemp K,Woldbye DP

更新日期：2001-03-01 00:00:00

abstract：:This review describes the role of modulation of intracellular adhesion molecule-1 (ICAM-1)/leukocyte function-associated antigen-1 (LFA-1) interaction in controlling autoimmune diseases or inducing immunotolerance. ICAM-1/LFA-1 interaction is essential for T-cell activation as well as for migration of T-cells to targe...

journal_title：Peptides

authors： Anderson ME,Siahaan TJ

更新日期：2003-03-01 00:00:00

abstract：:The distribution of urotensin I (UI) and corticotropin-releasing factor (CRF) immunoreactive (IR) structures was studied in the central nervous system (CNS) of the white sucker using the peroxidase-antiperoxidase immunocytochemical procedure. The close sequence homology between both peptides resulted in a high degree ...

journal_title：Peptides

authors： Yulis CR,Lederis K,Wong KL,Fisher AW

更新日期：1986-01-01 00:00:00

abstract：:Neurotensin(6-13) has been isolated and sequenced as the major form of neurotensin-like immunoreactivity (NTLI) in a human hepatic fibrolamellar carcinoma. Circulating NTLI in the patient, especially C-terminal, was very high. In additional studies, NT(6-13) was synthesized and compared with the purified tumor NTLI by...

journal_title：Peptides

authors： Read D,Shulkes A,Fernley R,Simpson R

更新日期：1991-07-01 00:00:00

abstract：:Solubilization of rat synaptic membranes by Triton X-100 followed by DEAE-cellulose chromatography allowed the separation of a phosphoramidon-sensitive endopeptidase that cleaved CCK-8. This enzymatic activity revealed similar if not identical to "enkephalinase A." A major cleavage point, at the Trp30-Met31 bond, and ...

journal_title：Peptides

authors： Deschodt-Lanckman M,Koulischer D,Przedborski S,Lauwereys M

更新日期：1984-05-01 00:00:00

abstract：:NPFF receptors are expressed in several brain regions directly or indirectly involved in cognition and behavior. However, the cognitive effects of the NPFF system have been poorly studied. Therefore, the aim of our study was to analyze the effects of i.c.v. injections of 1 DMe, a stable agonist of NPFF receptors, on b...

journal_title：Peptides

authors： Betourne A,Marty V,Ceccom J,Halley H,Lassalle JM,Zajac JM,Frances B,Mouledous L

更新日期：2010-02-01 00:00:00

abstract：:Modification to the structure of glucagon has provided a number of glucagon receptor antagonists with possible therapeutic application for diabetes. These novel peptide analogs include desHis(1)Pro(4)Glu(9)-glucagon and desHis(1)Pro(4)Glu(9)(Lys(30)PAL)-glucagon. This study has evaluated the metabolic benefits of once...

journal_title：Peptides

authors： McShane LM,Franklin ZJ,O'Harte FP,Irwin N

更新日期：2014-10-01 00:00:00

abstract：:Endogenous hemorphins, derived from degradation of the beta-chain of hemoglobin, lower arterial blood pressure and exert an antinociceptive action in experimental models of nociception. Hemopressin, derived from the alpha-chain of hemoglobin, also decreases blood pressure, but its effects on pain have not been studied...

journal_title：Peptides

authors： Dale CS,Pagano Rde L,Rioli V,Hyslop S,Giorgi R,Ferro ES

更新日期：2005-03-01 00:00:00

abstract：:The melanocortin 4 receptor (MC4R) plays an essential role in weight regulation. Recently we could show that the MC4R is able to form receptor dimers. In the present study we investigated the role of extracellular cysteine residues and the structure of the third extracellular loop for receptor dimerization. None of th...

journal_title：Peptides

authors： Elsner A,Tarnow P,Schaefer M,Ambrugger P,Krude H,Grüters A,Biebermann H

更新日期：2006-02-01 00:00:00

abstract：:It is well known that glucoprivation induces the release of counterregulatory hormones such as glucagon, and that the response is attenuated when the stimuli are repeated. Glucoprivation also activates orexigenic neurons and induces hyperphagic responses, although it remains unclear whether these responses are attenua...

journal_title：Peptides

authors： Ozawa Y,Arima H,Watanabe M,Shimizu H,Ito Y,Banno R,Sugimura Y,Ozaki N,Nagasaki H,Oiso Y

更新日期：2011-04-01 00:00:00

abstract：:Androgenic gland hormone (AGH) is known to be responsible for sex differentiation in crustaceans. The amino acid sequence of AGH-active fraction purified from androgenic glands of the terrestrial isopod Armadillidium vulgare was determined by immunoprecipitation employing three types of antibodies raised against diffe...

journal_title：Peptides

authors： Okuno A,Hasegawa Y,Ohira T,Nagasawa H

更新日期：2001-02-01 00:00:00

abstract：:The peptidome of the central nervous system of adult cabbage root fly, Delia radicum (L) was investigated using matrix assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS). Over twenty neuropeptides were identified from three different tissue sources, the combined brain/suboesophageal g...

journal_title：Peptides

authors： Audsley N,Matthews HJ,Down RE,Weaver RJ

更新日期：2011-03-01 00:00:00

abstract：:The effects of amiloride on ANF binding and ANF stimulation of cGMP were evaluated in rat glomeruli. Amiloride increased ANF binding to whole glomeruli and to glomerular membrane preparations. In contrast, amiloride enhanced ANF-stimulated cGMP accumulation only at 37 degrees C in whole glomeruli, but not at 4 degrees...

journal_title：Peptides

authors： Iwata T,Hardee E,Frohlich ED,Cole FE

更新日期：1989-05-01 00:00:00

abstract：:Ablation of the frontal neocortex markedly enhanced the antinociceptive and cataleptic actions of beta-endorphin injected into the lateral ventricle of rat brain. This enhanced response was not affected by simultaneous administration of cholecystokinin octapeptide (CCK-8). In sham-operated rats, however, CCK-8 suppres...

journal_title：Peptides

authors： Itoh S,Katsuura G

更新日期：1985-03-01 00:00:00