Abstract:
:ACTH/MSH(4-10) (10 micrograms/kg/b.i.d.; IP), administered to pregnant Sprague-Dawley rats during gestational days (GD) 3 to 12, significantly increased the metabolic activity of extensor digitorum longus (EDL) muscle at postnatal day 14. ACTH/MSH peptide, administered from day of birth to postnatal day 13, had no effect on EDL muscle metabolic activity using the 2,3,5-triphenyltetrazolium chloride indicator. By postnatal day 30, no differences were seen between the early prenatally treated group and saline controls. These results confirm our previous electrophysiological studies that showed that early prenatal ACTH/MSH(4-10) administration accelerates EDL muscle maturation.
journal_name
Peptidesjournal_title
Peptidesauthors
Rose KJ,Strand FLdoi
10.1016/0196-9781(90)90128-rsubject
Has Abstractpub_date
1990-01-01 00:00:00pages
177-9issue
1eissn
0196-9781issn
1873-5169pii
0196-9781(90)90128-Rjournal_volume
11pub_type
杂志文章相关文献
PEPTIDES文献大全abstract::Dissociated muscle cells prepared from hearts of the pulmonate snail Helix aspersa were used to study signal transduction induced by molluscan cardioactive peptides. The effects of SCPb on the cAMP levels of whole hearts and the cell preparation were compared. The cells responded to SCPb with a dose-dependent increase...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(97)00196-4
更新日期:1997-01-01 00:00:00
abstract::Cholecystokinin (CCK) and met-enkephalin (MEK) related peptides have been shown to alter feeding behavior subsequent to their injection into the peripheral circulation or directly into the brains of several species. To evaluate the potential role of endogenous brain pools of these peptides in feeding, groups of sheep ...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(85)90325-0
更新日期:1985-09-01 00:00:00
abstract::PACAP-27 and PACAP-38 are the exclusive physiological ligands for the mammalian PAC1 receptor. The role of C-terminal amidation of these ligands at that receptor was examined in neuroendocrine cells expressing the PAC1 receptor endogenously and in non-neuroendocrine cells in which the human and rat PAC1 receptors were...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2016.03.003
更新日期:2016-05-01 00:00:00
abstract::The aim of this study was to compare the actions of CCK neuropeptides within the nucleus accumbens (N.Acc) of alcohol preferring (Fawn-Hooded, FH) and alcohol nonpreferring (Wistar-Kyoto, WKY) rats. CCK-8S (30-300 nM) facilitated the K(+) stimulated release of [(3)H]dopamine (DA) from N.Acc prisms in both rat strains,...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(00)00159-5
更新日期:2000-03-01 00:00:00
abstract::Short synthetic peptides corresponding to sequences of complementarity-determining regions (CDRs) from different immunoglobulin families have been shown to induce antimicrobial, antiviral and antitumor activities regardless of the specificity of the original monoclonal antibody (mAb). Presently, we studied the in vitr...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2014.06.007
更新日期:2014-09-01 00:00:00
abstract::Combined use of the intraaxonal retrograde transport of the fluorescent marker 'true blue' with substance P (SP) immunocytochemistry has been used to trace the nodose ganglion projections of SP-containing neurons of the aortic depressor nerve. It has been found that (1) SP immunoreactive (SP-I) cell bodies are clearly...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(80)90015-7
更新日期:1980-01-01 00:00:00
abstract::Cocaine- and amphetamine-regulated transcript (CART) is a neurotransmitter and hormone, involved in the regulation of e.g. food intake, body weight, reward and addiction, and stress response. CART has also been found to affect insulin secretion and beta cell morphology, both in vivo and in vitro. Furthermore, CART aff...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2020.170431
更新日期:2021-01-01 00:00:00
abstract::To confirm and extend the results of previous studies which demonstrated central cardiovascular effects of vasopressin in anesthetized rats, we determined blood pressure and heart rate changes for 30 minutes after intracerebroventricular injections of arginine vasopressin, arginine vasotocin and oxytocin in conscious ...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(83)90008-6
更新日期:1983-09-01 00:00:00
abstract::C-type natriuretic peptide (CNP) is assuming increasing importance in cardiovascular disease, and in adults its plasma levels are related to clinical and functional disease severity. Data are scarce regarding the reference values for CNP in infancy. Aim of this study was to assess the reference intervals for CNP in hu...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2011.11.005
更新日期:2012-01-01 00:00:00
abstract::This review is part of a special issue dedicated to Opioid addiction, and examines the influential role of opioid peptides, opioid receptors and opiate drugs in mediating food intake and body weight control in rodents. This review postulates that opioid mediation of food intake was an example of "positive addictive" p...
journal_title:Peptides
pub_type: 杂志文章,评审
doi:10.1016/j.peptides.2019.04.008
更新日期:2019-06-01 00:00:00
abstract::Chicken-I and chicken-II gonadotropin-releasing hormone (cI-GnRH and cII-GnRH) were shown to be differentially distributed in the brain of a turtle, Trachemys scripta, by HPLC and specific radioimmunoassays. The cI-GnRH was most concentrated in the median eminence (ME), while cII-GnRH was most concentrated in the caud...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(93)90033-d
更新日期:1993-03-01 00:00:00
abstract::Numerous works associate the MCH peptide, and the hypothalamic neurons that produce it, to the feeding behavior and energy homeostasis. It is commonly admitted that MCH is an orexigenic peptide, and MCH neurons could be under the control of arcuate NPY and POMC neurons. However, the literature data is not always conco...
journal_title:Peptides
pub_type: 杂志文章,评审
doi:10.1016/j.peptides.2009.07.008
更新日期:2009-11-01 00:00:00
abstract::The presence of atrial natriuretic peptide (ANP) binding sites in the thymic cortex, medulla, and splenic white pulp suggests that this peptide may have immunoregulatory activity. We examined the effect of ANP on human natural killer (NK) cell activity. ANP significantly augmented NK cell cytotoxicity after twenty-fou...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(91)90145-f
更新日期:1991-07-01 00:00:00
abstract::Orexin (ORX) plays a critical role in reward-seeking behavior for natural rewards and drugs of abuse. The mesolimbic dopamine (DA) pathway that projects into the nucleus accumbens (NAc) from the ventral tegmental area is deeply involved in the neural mechanisms underlying reward, drug abuse and motivation. A recent st...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2010.10.023
更新日期:2011-02-01 00:00:00
abstract::Studies on the in vitro interaction of beta-endorphin with different biomembrane preparations, measured in terms of Ca2+ induced chlorotetracycline (CTC) fluorescence alterations indicate that beta-endorphin causes release of calcium ion from both synaptosomal and erythrocyte membrane stores but not from rat brain mit...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(83)90131-6
更新日期:1983-05-01 00:00:00
abstract::Thirty viral proteomes were examined for amino acid sequence similarity to the human proteome, and, in parallel, a control of 30 sets of human proteins was analyzed for internal human overlapping. We find that all of the analyzed 30 viral proteomes, independently of their structural or pathogenic characteristics, pres...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2008.05.022
更新日期:2008-10-01 00:00:00
abstract::To investigate the contribution of the N-terminal sequence of h-EGF to its biological activity and the formation of three intramolecular disulfide bonds by oxidative refolding via air oxidation, five derivatives of h-EGF with a single N-terminal amino acid deletion were synthesized by solid-phase synthesis. The homoge...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(94)00181-2
更新日期:1995-01-01 00:00:00
abstract::The antinociceptive effect of i.t.-administered Tyr-d-Arg-Phe-β-Ala (TAPA), an N-terminal tetrapeptide analog of dermorphin, was characterized in ddY mice. In the mouse tail-flick test, TAPA administered i.t. produced a potent antinociception. The antinociception induced by TAPA was significantly attenuated by i.t. pr...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2013.10.003
更新日期:2013-12-01 00:00:00
abstract::Intracerebroventricular injections of rat hypothalamic growth hormone-releasing factor (rhGRF) were examined for effects on food intake in free-feeding rats. It was found that, in picomole doses, rhGRF had a stimulatory effect on food intake. Examination of higher doses of rhGRF revealed a decrease in the facilitatory...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(88)90220-3
更新日期:1988-01-01 00:00:00
abstract::While neuropeptides of the allatostatin family inhibit in vitro production of juvenile hormone, which modulates aspects of development and reproduction in the cockroach, Diploptera punctata, they are susceptible to inactivation by peptidases in the hemolymph, gut, and bound to internal tissues. Patterns of peptidase c...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(98)00149-1
更新日期:1999-01-01 00:00:00
abstract::The effect of EGF on the incorporation of [3H]TdR into DNA (DNA synthesis) was determined in the esophagus, liver, pancreas, and kidney in mice standardized to 12 hours (hr) of light alternating with 12 hr of darkness. A question asked was whether intraperitoneally administered EGF could alter the circadian patterns o...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(87)90110-0
更新日期:1987-03-01 00:00:00
abstract::Vascular permeability and endothelial cell damage has been shown to occur in rats subjected to trauma with hemorrhagic-shock. Although the factors responsible for the endothelial cell injury are unknown, it has been hypothesized that toxic factors produced in response to hemorrhagic-shock originate in the gut and are ...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2005.05.001
更新日期:2005-12-01 00:00:00
abstract::The role of hippocampal dynorphin A (1-8) (Dyn A (1-8)) and kappa opioid receptors was investigated in the isolation-induced hypertensive rat (IHR). Male Sprague Dawley rats were either isolated (1 per cage) or grouped (3 per cage) for 7 days. Isolated rats exhibited increased blood pressure (systolic blood pressure 1...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/s0196-9781(00)00331-4
更新日期:2000-12-01 00:00:00
abstract::Cocaine- and amphetamine regulated transcript (CART) is a recently discovered anorexigenic peptide, widely expressed in the central nervous system. Included among presumed hypothalamic mediated functions of CART are inhibition of food intake, stimulation of energy expenditure and regulation of hypothalamic-pituitary a...
journal_title:Peptides
pub_type: 杂志文章,评审
doi:10.1016/j.peptides.2005.11.029
更新日期:2006-08-01 00:00:00
abstract::An important role for angiotensin IV (Ang IV) in the processes of learning and memory has now been well established. We have previously found that intracerebroventricular (ICV) administration of Ang IV as well as des-Phe6-Ang IV enhances learning of conditioned avoidance responses (CARs), facilitates recall of a passi...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2004.04.014
更新日期:2004-07-01 00:00:00
abstract::VIP stimulates adenylate cyclase activity of male and female rat anterior pituitaries and human prolactinomas, while dopamine inhibits the enzyme activity of female rat pituitaries and prolactinomas. A dopamine inhibited cyclase can be detected also in male rats provided the enzyme activity is increased by VIP. The an...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(84)90172-4
更新日期:1984-11-01 00:00:00
abstract::Brazilian freshwater stingrays, Potamotrygon gr. orbigyni, are relatively common in the middle-western regions of Brazil, where they are considered an important public health threat. In order to identify some of their naturally occurring toxin peptides available in very low amounts, we combine analytical protocols suc...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2009.08.004
更新日期:2009-12-01 00:00:00
abstract::The presence of alpha-hANP immunoreactive material in human heart and plasma was investigated with a specific and sensitive radioimmunoassay and immunohistochemical method. It was found that alpha-hANP immunoreactive staining of specific atrial granules was located around the nucleus of atrial cardiocytes. No immunore...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/0196-9781(86)90057-4
更新日期:1986-01-01 00:00:00
abstract::Calcification-associated peptide (CAP)-1 is considered to play an important role in calcification of the exoskeleton of the crayfish, Procambarus clarkii. In this study, in order to clarify the molecular mechanism of calcification, we constructed expression systems of recombinant molecules of CAP-1 and its related pep...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2006.12.005
更新日期:2007-03-01 00:00:00
abstract::Insect flight requires rapid mobilization of energy reserves during flight, which is mediated and regulated by hormonal control via adipokinetic hormones. The structure of the G-protein receptors to which these hormones bind, are crucial in understanding many of the physiological processes in which they play a central...
journal_title:Peptides
pub_type: 杂志文章
doi:10.1016/j.peptides.2010.08.017
更新日期:2011-03-01 00:00:00