Abstract：
:The effect of EGF on the incorporation of [3H]TdR into DNA (DNA synthesis) was determined in the esophagus, liver, pancreas, and kidney in mice standardized to 12 hours (hr) of light alternating with 12 hr of darkness. A question asked was whether intraperitoneally administered EGF could alter the circadian patterns of DNA synthesis in these organs. The most marked effects of EGF were: an increase in DNA synthesis but only after a specific duration of time after treatment, ranging from 8 to 23 hr, which differed for each tissue, a similarity in the response of the esophagus in both ad lib fed and fasted mice, but not in the response of the liver, where the stimulatory effect of EGF observed in fed mice was dramatically reduced in fasted ones, and an advance in the phasing of the circadian rhythm in DNA synthesis of the esophagus by about 12 hr. In addition, no sex differences in fasted animals were found under the conditions of this study.
journal_name
Peptidesjournal_title
Peptidesauthors
Scheving LA,Tsai TH,Scheving LE,Hoke WSdoi
10.1016/0196-9781(87)90110-0subject
Has Abstractpub_date
1987-03-01 00:00:00pages
347-53issue
2eissn
0196-9781issn
1873-5169pii
0196-9781(87)90110-0journal_volume
8pub_type
杂志文章相关文献
PEPTIDES文献大全abstract：:Interleukin-1 beta (IL-1β) significantly influences cognitive processes. Treatments which raise the level of IL-1β in the brain impair memory consolidation in contextual fear conditioning. However, the effect of IL-1β on memory reconsolidation has not yet been established. The melanocortin α-melanocyte-stimulating hor...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2010.07.018
更新日期：2010-11-01 00:00:00
abstract：:Male Holtzman albino and Long-Evans hooded rats were administered one microgram of arginine vasopressin (AVP) or a placebo each day after the acquisition trials of a visual white-black discrimination. Animals were then trained in the reversal of the discrimination. Performance was assessed by the number of trials to c...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(89)90099-5
更新日期：1989-01-01 00:00:00
abstract：:Epithelial to mesenchymal transition (EMT), a process whereby fully differentiated epithelial cells transition to a mesenchymal phenotype, has been implicated in the pathogenesis of renal fibrosis. Apelin, a bioactive peptide, has recently been recognized to protect against renal profibrotic activity, but the underlyi...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2017.08.006
更新日期：2017-10-01 00:00:00
abstract：:Two molecular forms of gonadotropin-releasing hormone (GnRH) were identified in the extracts of various brain areas, spinal cord and pituitary in female and male goldfish and had chromatographic and immunological properties similar to [His5, Trp7, Tyr8]-GnRH (cGnRH-II) and [Trp7,Leu8]-GnRH (sGnRH). Radioimmunoassay us...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(88)90174-x
更新日期：1988-05-01 00:00:00
abstract：:Endocrine regulation in vertebrates is critical for the adaptation and regulation of homeostasis. The G protein-coupled receptor (GPCR) signaling transduction system represents one of the most ancient forms of cell surface signaling. Recently, comparative sequence analysis has aided in the identification and pairing o...
journal_title：Peptides
pub_type： 杂志文章,评审
doi：10.1016/j.peptides.2004.05.021
更新日期：2004-10-01 00:00:00
abstract：:Solubilization of rat synaptic membranes by Triton X-100 followed by DEAE-cellulose chromatography allowed the separation of a phosphoramidon-sensitive endopeptidase that cleaved CCK-8. This enzymatic activity revealed similar if not identical to "enkephalinase A." A major cleavage point, at the Trp30-Met31 bond, and ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(84)90098-6
更新日期：1984-05-01 00:00:00
abstract：:Somatostatin has been proposed as a regulatory peptide of nutrient entry and fuel homeostasis because of its ability to inhibit the release of substances involved in food digestion and metabolism. The aim of the study was to evaluate the somatostatin response to a test meal in type I diabetics at the clinical onset of...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(86)90204-4
更新日期：1986-01-01 00:00:00
abstract：:Two peptides, with a molecular mass of about 11 kDa and an N-terminal sequence abundant in arginine and glutamine residues, were isolated from wax gourd seeds. The isolation protocol included affinity chromatography on Affi-gel blue gel, ion-exchange chromatography on Mono-S and gel filtration on Superdex 75. The pept...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/s0196-9781(02)00271-1
更新日期：2003-01-01 00:00:00
abstract：:Leukemia inhibitory factor (LIF) overexpression, induced by the intracerebroventricular (i.c.v.) injection of an recombinant adeno-associated viral vector encoding LIF (rAAV-LIF), resulted in a dose-dependent reduction in body weight (BW) gain, food intake (FI) and adiposity, evidenced by suppression of serum leptin a...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/s0196-9781(02)00021-9
更新日期：2002-05-01 00:00:00
abstract：:The aim was to study the effects of C-type natriuretic peptide (CNP) on mean arterial pressure (MAP) and the cardiovascular nitric oxide (NO) system in spontaneously hypertensive rats (SHR), and to investigate the signaling pathways involved in this interaction. SHR and WKY rats were infused with saline or CNP. MAP an...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2010.03.030
更新日期：2010-07-01 00:00:00
abstract：:The antinociceptive effect of i.t.-administered Tyr-d-Arg-Phe-β-Ala (TAPA), an N-terminal tetrapeptide analog of dermorphin, was characterized in ddY mice. In the mouse tail-flick test, TAPA administered i.t. produced a potent antinociception. The antinociception induced by TAPA was significantly attenuated by i.t. pr...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2013.10.003
更新日期：2013-12-01 00:00:00
abstract：:In sheep, arginine vasopressin (AVP) and corticotropin-releasing factor (CRF) stimulate adrenocorticotropic hormone (ACTH) secretion. Increased hypothalamic secretion of these peptides at the end of gestation initiates parturition in this species. We hypothesized that CRF and/or AVP content in the fetal hypothalamus i...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(95)02060-8
更新日期：1996-01-01 00:00:00
abstract：:While neuropeptides of the allatostatin family inhibit in vitro production of juvenile hormone, which modulates aspects of development and reproduction in the cockroach, Diploptera punctata, they are susceptible to inactivation by peptidases in the hemolymph, gut, and bound to internal tissues. Patterns of peptidase c...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/s0196-9781(98)00149-1
更新日期：1999-01-01 00:00:00
abstract：:Using a one-bottle taste aversion conditioning paradigm, sulfated cholecystokinin(26-33) (CCK-8) has again been shown to induce taste aversion conditioning in rats. Even though the effective doses of CCK-8 are relatively high, they do not induce as strong an aversion as has been demonstrated with LiCl. This pharmacody...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(95)00001-z
更新日期：1995-01-01 00:00:00
abstract：:The present study sought to examine the mechanism of substance P to modulate the antinociceptive action of intrathecal (i.t.) morphine in paw-licking/biting response evoked by subcutaneous injection of capsaicin into the plantar surface of the hindpaw in mice. The i.t. injection of morphine inhibited capsaicin-induced...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2009.06.002
更新日期：2009-09-01 00:00:00
abstract：:A novel peptide hormone, atrial natriuretic factor (ANF), was recently isolated and characterized in mammalian atria. This hormone has potent natriuretic diuretic and vasorelaxant activities. Since ANF bioactivity was initially found in atria but not in ventricles, it was assumed that the ANF gene is specifically expr...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(86)90145-2
更新日期：1986-11-01 00:00:00
abstract：:Various enkephalins (ENK) have been reported to alter heart rate, systemic blood pressure, and respiratory function but with variable results. We previously found that pentobarbital anesthesia reversed the increases in heart rate and systemic arterial blood pressure produced by Leu5-ENK in the dog. We have now studied...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/s0196-9781(81)80095-2
更新日期：1981-01-01 00:00:00
abstract：:Antimicrobial peptides allegedly exert their action on microbial membranes. Bovine lactoferrin enfold two antimicrobial domains, lactoferricin B (LFcin B) and lactoferrampin (LFampin). Effects of representative peptides thereof on the membranes of Candida albicans and Escherichia coli were investigated. Confocal laser...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2005.02.011
更新日期：2005-09-01 00:00:00
abstract：:Using Surface Plasmon Resonance (SPR) we investigated the interaction of seven neuropeptides with different characteristics and beta-amyloid (Abeta42) peptide, with membranes containing gangliosides. A wide range of affinities characterized the bindings (K(D) = 10(-3)- 10(-7) M), following the scheme: for GM1, Abeta42...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/s0196-9781(01)00432-6
更新日期：2001-07-01 00:00:00
abstract：:Thyroglobulin (Tg) is cleaved into several peptides during thyroid hormone synthesis, an oxidative process. P40, an iodinated C-terminal peptide from human Tg, has a molecular weight of about 40 kDa and contains two hormonogenic sites. P40 is the smallest peptide that is still recognized by monoclonal antibodies from ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2004.03.020
更新日期：2004-06-01 00:00:00
abstract：:So far numerous antimicrobial peptides have been characterized from amphibians. In this work, a new family of antimicrobial peptides, named shuchin, was purified and characterized from skin secretions of the frog, Rana shuchinae that lives in freezing mountains. Totally two members of shuchin (shuchin 1 and 2) were id...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2010.05.014
更新日期：2010-09-01 00:00:00
abstract：:The distributions of neuropeptides in paraffin-embedded tissue sections (PETS) of the eyestalk, brain, and thoracic ganglia of the shrimp Penaeus monodon were visualized by imaging mass spectrometry (IMS). Peptide signals were obtained from PETS without affecting morphological features. Twenty-nine neuropeptides compr...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2011.03.021
更新日期：2012-03-01 00:00:00
abstract：:There are two distinct mRNAs that encode the precursor to gastrin-releasing peptide (GRP) in rat brain. These two messages arise from separate transcription initiation sites located approximately 400 base pairs apart, which are presumably regulated by separate promoters. In the present study, we mapped the distributio...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(89)90052-1
更新日期：1989-03-01 00:00:00
abstract：:Radiation enteritis occurs as a response to abdominal radiation, which can cause mucosal damage in the gastrointestinal mucosal epithelium. The small intestine is one of the most radiosensitive organs in the abdomen. The present study was undertaken to investigate the effect of octreotide (OCT) administration on heme ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2005.11.012
更新日期：2006-06-01 00:00:00
abstract：:This review describes the role of modulation of intracellular adhesion molecule-1 (ICAM-1)/leukocyte function-associated antigen-1 (LFA-1) interaction in controlling autoimmune diseases or inducing immunotolerance. ICAM-1/LFA-1 interaction is essential for T-cell activation as well as for migration of T-cells to targe...
journal_title：Peptides
pub_type： 杂志文章,评审
doi：10.1016/s0196-9781(03)00083-4
更新日期：2003-03-01 00:00:00
abstract：:Double-labeling immunofluorescence of guinea pig tracheobronchial lymph nodes revealed complete coincidence of SP and CGRP immunoreactivities in perivascular nerves and axons of the medullary lymphatic tissue. Additional dynorphin A or cholecystokinin immunoreactivity was seen only in some of the medullary fibers. Ult...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(90)90103-c
更新日期：1990-01-01 00:00:00
abstract：:Bacillus thuringiensis Cry toxins recognizes their target cells in part by the binding to glycosyl-phosphatidyl-inositol (GPI) anchored proteins such as aminopeptidase-N (APN) or alkaline phosphatases (ALP). Treatment of Tenebrio molitor brush border membrane vesicles (BBMV) with phospholipase C that cleaves out GPI-a...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2012.05.019
更新日期：2013-03-01 00:00:00
abstract：:The degradation of synthetic Manduca sexta allatostatin (Manse-AS) and allatotropin (Manse-AT), by enzymes of the foregut of larvae of the tomato moth, Lacanobia oleracea was investigated using reversed-phase high performance liquid chromatography (RP-HPLC) together with matrix-assisted laser desorption ionization-tim...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/s0196-9781(02)00189-4
更新日期：2002-11-01 00:00:00
abstract：:We studied the ability of NPFF, a FMRFamide-like peptide with certain antiopiate properties, to affect the inhibitory effect of morphine on the electrically induced contraction of guinea pig ileum. Neuropeptide FF had no effect when administered alone but reduced morphine inhibition in a noncompetitive manner. Neurope...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(93)90078-u
更新日期：1993-09-01 00:00:00
abstract：:We employed a proteomic approach to search for peptides that have a physiological role in labor. Cervicovaginal secretions were collected at term from women in labor and women at term not in labor. Samples were spotted onto weak cation exchange chips (WCX-2) and analyzed using Surface-Enhanced Laser Desorption Ionizat...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2006.03.015
更新日期：2006-07-01 00:00:00
