Ultrastructural effects of antimicrobial peptides from bovine lactoferrin on the membranes of Candida albicans and Escherichia coli.

abstract：:Urotensin-II (U-II), a cyclic peptide widely expressed in blood vessels, has diverse vascular actions that range from potent vasoconstriction to vasodilation. Although, U-II-induced vasodilation has been shown to be partially dependent on nitric oxide (NO), the involvement of vascular adventitia-derived NO, remains un...

journal_title：Peptides

authors： Lin L,Ding WH,Jiang W,Zhang YG,Qi YF,Yuan WJ,Tang CS

更新日期：2004-11-01 00:00:00

abstract：:Cardiac preconditioning represents the most potent and consistently reproducible method of rescuing heart tissue from undergoing irreversible ischemic damage. One of the major goals of the current cardiovascular research is to identify a reliable cardioprotective intervention that can salvage ischemic myocardium. The ...

journal_title：Peptides

authors： Alizadeh AM,Faghihi M,Sadeghipour HR,Mohammadghasemi F,Imani A,Houshmand F,Khori V

更新日期：2010-07-01 00:00:00

abstract：:Previous physiological studies have suggested central roles of brain natriuretic peptide (BNP). However, little information is available about the localization of BNP in the brain. In this study, we determined cDNA sequence encoding the entire coding region of prepro-BNP of Japanese and cynomologus monkeys, and then e...

journal_title：Peptides

authors： Abdelalim EM,Takada T,Torii R,Tooyama I

更新日期：2006-07-01 00:00:00

abstract：:The objective of this study was to explore the effects of the endogenous opioid peptide dynorphin A(1-13) on the CNS regulation of blood pressure and heart rate. Wistar rats, anesthetized with pentobarbital and halothane, received dynorphin A(1-13) microinjected into the anterior hypothalamus area (AHA), the posterior...

journal_title：Peptides

authors： Rabkin SW

更新日期：1993-11-01 00:00:00

abstract：:The aim of our study was to determine whether a meal modifies the antisecretory response induced by PYY and the structural requirements to elicit antisecretory effects of analogue PYY(22-36) for potential antidiarrhea therapy. The variations in short-circuit current (Isc) due to the modification of ionic transport acr...

journal_title：Peptides

authors： Eto B,Boisset M,Eden P,Balasubramaniam A,Desjeux JF

更新日期：1995-01-01 00:00:00

abstract：:Tissue inhibitor of metalloproteinases-2 (TIMP-2) inhibits angiogenesis by several mechanisms involving either MMP inhibition or direct endothelial cell binding. The primary aim of this study was to identify the TIMP-2 region involved in binding to the previously identified receptor integrin α3β1, and to determine whe...

journal_title：Peptides

authors： Seo DW,Saxinger WC,Guedez L,Cantelmo AR,Albini A,Stetler-Stevenson WG

更新日期：2011-09-01 00:00:00

abstract：:Parasitic worms come from two very different phyla-Platyhelminthes (flatworms) and Nematoda (roundworms). Although both phyla possess nervous systems with highly developed peptidergic components, there are key differences in the structure and action of native neuropeptides in the two groups. For example, the most abun...

journal_title：Peptides

authors： Day TA,Maule AG

更新日期：1999-01-01 00:00:00

abstract：:Plant defensins are a prominent family of cationic peptides in the plant kingdom. They are structurally and functionally related to defensins that have been previously characterized in mammals and insects. They present molecular masses between 5 and 7kDa and possess a pattern of eight conserved Cys residues. The three...

journal_title：Peptides

authors： Carvalho Ade O,Gomes VM

更新日期：2009-05-01 00:00:00

abstract：:The discovery of several adipokines with diverse activities and their involvement in regulation of various pathophysiological functions of human body has challenged the researchers. In the family of adipokine, chemerin is a novel and unique addition. Ever since the first report on chemerin as a chemo-attractant protei...

journal_title：Peptides

authors： Fatima SS,Rehman R,Baig M,Khan TA

更新日期：2014-12-01 00:00:00

abstract：:We studied the effects of calcitonin gene-related peptide (CGRP) on ciliary beat frequency (CBF) and electrical properties of canine tracheal epithelium by a photoelectric method and Ussing's short-circuit technique, respectively. CGRP dose dependently increased CBF, an effect that was accompanied by elevation of intr...

journal_title：Peptides

authors： Tamaoki J,Kanemura T,Kobayashi K,Sakai N,Takizawa T

更新日期：1989-09-01 00:00:00

abstract：:Malondialdehyde-modified low-density lipoprotein (MDA-LDL) is recognized as a surrogate marker of lipid oxidation and is associated with arteriosclerosis. However, there are limited reports on the relationship between heart failure and MDA-LDL. Therefore, we aimed to determine whether MDA-LDL is activated in patients w...

journal_title：Peptides

authors： Hasegawa J,Ogawa K,Kawai M,Tanaka TD,Nagoshi T,Minai K,Ogawa T,Yoshimura M

更新日期：2021-01-01 00:00:00

abstract：:Alzheimer's disease is one of the most common dementia among elderly worldwide. There is no therapeutic drugs until now to treat effectively this disease. One main reason is due to the poorly understood mechanism of Aβ peptide aggregation, which plays a crucial role in the development of Alzheimer's disease. It remain...

journal_title：Peptides

authors： Tran L,Ha-Duong T

更新日期：2015-07-01 00:00:00

abstract：:An immunohistochemical mapping study in the brain and upper spinal cord of the turtle Testudo hermanni Gmelin revealed a wide distribution of somatostatin perikarya and fibres. Within the telencephalon, somatostatin perikarya are present in the anterior olfactory nucleus, in the medial, dorsomedial and dorsal cortex, ...

journal_title：Peptides

authors： Weindl A,Triepel J,Kuchling G

更新日期：1984-01-01 00:00:00

abstract：:A novel 6.6 kDa antifungal peptide (NFAP) from the culture supernatant of the mold, Neosartorya fischeri (anamorf: Aspergillus fischerianus), and its encoding gene were isolated in this study. NFAP is a small, basic and cysteine-rich protein consisting of 57 amino acid residues. It shows 37.9-50% homology to similar p...

journal_title：Peptides

authors： Kovács L,Virágh M,Takó M,Papp T,Vágvölgyi C,Galgóczy L

更新日期：2011-08-01 00:00:00

abstract：:The term "oxidative stress" indicates a set of chemical reactions unleashed by a disparate number of events inducing DNA damage, lipid peroxidation, protein modification and other effects, which are responsible of altering the physiological status of cells or tissues. Excessive Reactive Oxygen Species (ROS) levels may...

journal_title：Peptides

authors： Sandomenico A,Severino V,Apone F,De Lucia A,Caporale A,Doti N,Russo A,Russo R,Rega C,Del Giacco T,Falcigno L,Ruvo M,Chambery A

更新日期：2017-03-01 00:00:00

abstract：:Jingzhaotoxin-II (JZTX-II) is a 32-residue peptide from the Chinese tarantula Chilobrachys jingzhao venom, and preferentially inhibits the fast inactivation of the voltage-gated sodium channels (VGSCs) in rat cardiac myocytes. In the present study, we elucidated the action mechanism of JZTX-II inhibiting hNav1.5, a VG...

journal_title：Peptides

authors： Huang Y,Zhou X,Tang C,Zhang Y,Tao H,Chen P,Liu Z

更新日期：2015-06-01 00:00:00

abstract：:Brazilian freshwater stingrays, Potamotrygon gr. orbigyni, are relatively common in the middle-western regions of Brazil, where they are considered an important public health threat. In order to identify some of their naturally occurring toxin peptides available in very low amounts, we combine analytical protocols suc...

journal_title：Peptides

authors： Conceição K,Santos JM,Bruni FM,Klitzke CF,Marques EE,Borges MH,Melo RL,Fernandez JH,Lopes-Ferreira M

更新日期：2009-12-01 00:00:00

abstract：:The influence of central vs. peripheral administration of specific type A and type B CCK receptor antagonists (L364,718 and L365,260, respectively) on colonic motor hyperactivity induced by feeding and CCK8 was investigated in dogs with strain-gauge transducers implanted on the proximal and transverse colon. Intraveno...

journal_title：Peptides

authors： Gue M,Bueno L

更新日期：1991-05-01 00:00:00

abstract：:Bacillus thuringiensis subsp. israelensis (Bti) produces at least four different crystal proteins that are specifically toxic to different mosquito species and that belong to two non-related family of toxins, Cry and Cyt named Cry4Aa, Cry4Ba, Cry11Aa and Cyt1Aa. Cyt1Aa enhances the activity of Cry4Aa, Cry4Ba or Cry11A...

journal_title：Peptides

authors： Cantón PE,Zanicthe Reyes EZ,Ruiz de Escudero I,Bravo A,Soberón M

更新日期：2011-03-01 00:00:00

abstract：:Neuronostatin is a 13-amino acid amidated peptide widely distributed in various organs including gastrointestinal tract. However, the effect of neuronostatin on gastrointestinal motility has not been well characterized. In the present work, effects of central administration of neuronostatin on gastric emptying and gas...

journal_title：Peptides

authors： Su SF,Yang AM,Yang SB,Wang NB,Lu SS,Wang HH,Chen Q

更新日期：2012-05-01 00:00:00

abstract：:The involvement of spinal opioid receptors and spinal monoaminergic systems, in the antinociceptive effect of intrathecal (IT) salmon calcitonin, has been evaluated by means of the hot plate test, in the rat. Intrathecal pretreatment with 40 micrograms MR 1452 and 40 micrograms ICI 154,129, purported selective antagon...

journal_title：Peptides

authors： Candeletti S,Romualdi P,Spadaro C,Spampinato S,Ferri S

更新日期：1985-01-01 00:00:00

abstract：:Pheromone biosynthesis activating neuropeptide (PBAN) produced in the subesophageal ganglion stimulates pheromone production in the pheromone gland. A cDNA isolated from female adult heads of the diamondback moth (Plutella xylostella (L.)) encodes 193 amino acids including PBAN, designated as Plx-PBAN, and four other ...

journal_title：Peptides

authors： Lee DW,Boo KS

更新日期：2005-12-01 00:00:00

abstract：:Receptor binding analysis was performed in the renal medulla from 2-month-old rats, an extrapituitary tissue containing the highest level of GHRH receptor mRNA. At 4 degrees C, in the presence of a cocktail of protease inhibitors, binding of [125I-Tyr(10)]hGHRH (1-44)NH(2) to medullary homogenates was specific, time-d...

journal_title：Peptides

authors： Boulanger L,Girard N,Strecko J,Gaudreau P

更新日期：2002-06-01 00:00:00

abstract：:Previous studies have shown that the nervous system and other tissues of molluscs contain a number of peptides that potently excite molluscan hearts. Two such peptides, termed small cardioactive peptides A and B (SCPA and SCPB) are present in large quantities in the nervous system of Aplysia. These peptides are widely...

journal_title：Peptides

authors： Lloyd PE,Kupfermann I,Weiss KR

更新日期：1987-01-01 00:00:00

abstract：:The effects of adrenomedullin (ADM) on C6 glioma cells were investigated. [125I]ADM bound with high affinity (Kd = 24 nM) to a single class of sites (Bmax = 36,000/cell) in C6 cells. Specific [125I]ADM binding was inhibited with high affinity by ADM (IC50 value of 10 nM) but not ADM(22-52) or pro-adrenomedullin N-term...

journal_title：Peptides

authors： Moody TW,Miller MJ,Mártinez A,Unsworth E,Cuttitta F

更新日期：1997-01-01 00:00:00

abstract：:A novel protein expressed by entero-endocrine cells of the mouse stomach was named prepromotilin Related Peptide (ppMTLRP) since it shares sequence similarities with the prepromotilin (Tomasetto et al.). The mouse ppMTLRP was found identical to the rat precursor of ghrelin (ppghrelin), an endogenous ligand specific fo...

journal_title：Peptides

authors： Tomasetto C,Wendling C,Rio MC,Poitras P

更新日期：2001-12-01 00:00:00

abstract：:More than 40 peptides belonging to the -Y/FXFGL-NH(2) allatostatin superfamily have been isolated and identified from the central nervous system (CNS) of the tiger prawn, Penaeus monodon (Crustacea: Penaeidea). The peptides can be arranged in seven sub-groups according to the variable post-tyrosyl residue represented ...

journal_title：Peptides

authors： Duve H,Johnsen AH,Scott AG,Thorpe A

更新日期：2002-06-01 00:00:00

abstract：:The presence of a putative GRP receptor on rat pancreatic particulate membranes was demonstrated by covalent cross-linking to 125I-gastrin releasing peptide (GRP), which revealed a radioactive band with Mr = 80-90 kDa on reduced SDS-PAGE. Fresh rat pancreatic membranes contained a GRP receptor which was solubilized wi...

journal_title：Peptides

authors： Kane MA,Kelley K,Ross SE,Portanova LB

更新日期：1991-03-01 00:00:00

abstract：:The role of neuropeptides in cardiomyopathy-associated heart failure has been garnering more attention. Several neuropeptides--Neuropeptide Y (NPY), vasoactive intestinal peptide (VIP), calcitonin gene related peptide (CGRP), substance P (SP) and their receptors have been studied in the various types of cardiomyopathi...

journal_title：Peptides

authors： Dvorakova MC,Kruzliak P,Rabkin SW

更新日期：2014-11-01 00:00:00

abstract：:We have evaluated a new immunoradiometric assay (IRMA) for calcitonin (CT) (Medgenix, Belgium). The detection limit of immunoreactive CT (IR-CT) was 2.8 pg/ml, and plasma levels of IR-CT of 134 healthy adults (dynamic range, 2.8-1000 pg/ml) were < 19 pg/ml (median 4.1 pg/ml). Both basal and pentagastrin-stimulated IR-...

journal_title：Peptides

authors： Wimalawansa SJ,Bailey F

更新日期：1995-01-01 00:00:00