Abstract:
:Two peptides, with a molecular mass of about 11 kDa and an N-terminal sequence abundant in arginine and glutamine residues, were isolated from wax gourd seeds. The isolation protocol included affinity chromatography on Affi-gel blue gel, ion-exchange chromatography on Mono-S and gel filtration on Superdex 75. The peptides, designated alpha- and beta-benincasins, inhibited cell-free translation in a rabbit reticulocyte lysate system with an IC(50) of 20 and 320 pM, respectively. Alpha-benincasin exhibited weak antifungal activity toward Coprinus comatus and Physalospora piricola but not toward Mycosphaerella arachidicola.
journal_name
Peptidesjournal_title
Peptidesauthors
Ng TB,Parkash A,Tso WWdoi
10.1016/s0196-9781(02)00271-1subject
Has Abstractpub_date
2003-01-01 00:00:00pages
11-6issue
1eissn
0196-9781issn
1873-5169pii
S0196978102002711journal_volume
24pub_type
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