Abstract:
:Combined use of the intraaxonal retrograde transport of the fluorescent marker 'true blue' with substance P (SP) immunocytochemistry has been used to trace the nodose ganglion projections of SP-containing neurons of the aortic depressor nerve. It has been found that (1) SP immunoreactive (SP-I) cell bodies are clearly demonstrable in clusters in the rostral part of the nodose ganglion without the aid of colchicine pretreatment; (2) 'true blue' is retrogradely transported to the nodose ganglion following its application to the central cut end of the aortic nerve; (3) 'true blue' fluorescence and SP fluorescent immunoreactivity can be visualized in the same tissue section and certain cell bodies in the nodose ganglia contain both SP-I and retrogradely transported 'true blue'. These results indicate that the aortic nerve which projects from the aortic arch baro- and/or chemoreceptors to brainstem vasomotor centers contains SP-I afferent fibers which emanate form the nodose ganglion.
journal_name
Peptidesjournal_title
Peptidesauthors
Helke CJ,Goldman W,Jacobowitz DMdoi
10.1016/0196-9781(80)90015-7subject
Has Abstractpub_date
1980-01-01 00:00:00pages
359-64issue
4eissn
0196-9781issn
1873-5169pii
0196-9781(80)90015-7journal_volume
1pub_type
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