An experimental anatomical study on the optic nerve fibers in the rat: courses of the accessory optic tract.

abstract：:Microinjections of monosodium glutamate (MSG; 300 microgram/0.5 microliter) into the hippocampus of the adult rat result in only marginal damage to local neurons. Perforant path transections, removing glutamatergic afferents to hippocampal granule cells, make the latter markedly more vulnerable to a subsequent MSG inj...

journal_title：Brain research

authors： Köhler C,Schwarcz R

更新日期：1981-05-04 00:00:00

abstract：:Experiments were conducted to investigate whether or not reciprocal descending commands occur simultaneously in the brain as well as the phasic changes in the agonist facilitation and the antagonist inhibition involved in the initiation of varying forces of ankle dorsiflexion. The H-reflex and reaction time method wer...

journal_title：Brain research

authors： Kasai T,Komiyama T

更新日期：1988-05-03 00:00:00

abstract：:The anteroventral subdivision of the medial amygdala (MeAV) is one of the vomeronasal structures involved in the control of hormonally dependent behaviors such as sexual and agonistic behaviors in rats. The present study investigates some anatomical and neurochemical parameters of this nucleus (volume, number of neuro...

journal_title：Brain research

authors： Carrillo B,Pinos H,Guillamón A,Panzica G,Collado P

更新日期：2007-05-30 00:00:00

abstract：:Developmental delay, cognitive impairment, and refractory epilepsy are the most frequent consequences found in patients suffering from malformations of cortical development (MCD). However, therapeutic options for these psychiatric and neurological comorbidities are currently limited. The development of white matter un...

journal_title：Brain research

authors： Ma L,Yang F,Zhao R,Li L,Kang X,Xiao L,Jiang W

更新日期：2015-10-05 00:00:00

abstract：:Intravenous administration of the cholecystokinin (CCK) antagonist lorglumide (LORG) reversed chronic haloperidol (CHAL)-induced depolarization inactivation (DI) of dopamine (DA) cells in both the A9 and A10 areas. Moreover, microinjection of LORG, but not naloxone, directly into the medial nucleus accumbens (mNAc) do...

journal_title：Brain research

authors： Jiang LH,Kasser RJ,Wang RY

更新日期：1988-11-08 00:00:00

abstract：:Abeta amyloidosis and tauopathy are characteristic changes in the brain of Alzheimer's disease. Although much evidence suggests that Abeta deposit is a critical initiation factor, the pathological pathway between Abeta amyloidosis and tau accumulation remains unclear. Tau accumulation was examined in the doubly transg...

journal_title：Brain research

authors： Samura E,Shoji M,Kawarabayashi T,Sasaki A,Matsubara E,Murakami T,Wuhua X,Tamura S,Ikeda M,Ishiguro K,Saido TC,Westaway D,St George Hyslop P,Harigaya Y,Abe K

更新日期：2006-06-13 00:00:00

abstract：:Numerous studies with PC12 cells have suggested that the mitogen-activated protein (MAP) kinase pathway might play a major role in the neuronal differentiation that is induced by nerve growth factor (NGF). Cells of the PC12D subline extend neurites within several hours in response to NGF in the presence of inhibitors ...

journal_title：Brain research

authors： Sano M,Kitajima S

更新日期：1998-03-02 00:00:00

abstract：:Sleep is posited to be a fundamental property of groups of highly interconnected neurons and regulated in part by activity-dependent sleep regulatory substances such as tumor necrosis factor alpha (TNFalpha). We show that the unilateral local application of TNFalpha onto the somatosensory cortex of rats induced state-...

journal_title：Brain research

authors： Yoshida H,Peterfi Z,García-García F,Kirkpatrick R,Yasuda T,Krueger JM

更新日期：2004-05-29 00:00:00

abstract：:Previous studies have shown that access to conceptual/semantic information precedes phonological access in alphabetic language production such as English or Dutch. The present study investigated the time course of semantic and orthographic encoding in Chinese (a non-alphabetic language) spoken word production. Partici...

journal_title：Brain research

authors： Zhang Q,Damian MF

更新日期：2009-06-01 00:00:00

abstract：:The distribution and density of noradrenergic (NA) and serotonergic (5-HT) varicosities in the superior olive (SO) and periolivary region (PO) and their relationship to olivocochlear neurons was studied. Antibodies against 5-HT and the NA precursor enzyme dopamine beta-hydroxylase were utilized to examine the density ...

journal_title：Brain research

authors： Woods CI,Azeredo WJ

更新日期：1999-07-31 00:00:00

abstract：:Anisomycin is both a well-established protein synthesis inhibitor and a potent activator of the p38/JNK MAPK pathway. It has been used to block the late phase of long-term potentiation (LTP) and long-term depression (LTD) in hippocampus. In this study, we have found that anisomycin produces a time-dependent decline in...

journal_title：Brain research

authors： Xiong W,Kojic LZ,Zhang L,Prasad SS,Douglas R,Wang Y,Cynader MS

更新日期：2006-04-26 00:00:00

abstract：:Opioid receptor subtype antagonists differentially alter food intake under deprivation (24 h), glucoprivic (2-deoxy-D-glucose, 500 mg/kg, i.p.) or palatable (10% sucrose) conditions with mu (beta-funaltrexamine) and kappa (nor-binaltorphamine), but not delta1 ([D-Ala2,Leu5,Cys6]enkephalin) opioid antagonists reducing ...

journal_title：Brain research

authors： Ragnauth A,Ruegg H,Bodnar RJ

更新日期：1997-08-29 00:00:00

abstract：:Intracellular recordings were made from Renshaw cells in the cat. Recurrent excitatory postsynaptic potentials (EPSPs) were elicited by antidromic stimulation of the ventral roots. These EPSPs had a simple monophasic time course without a spike-like peak reported by previous authors. No hyperpolarization could be dete...

journal_title：Brain research

authors： Walmsley B,Tracey DJ

更新日期：1981-10-26 00:00:00

abstract：:PC12D cells, a subline of PC12 cells, extend neurites very rapidly in response to NGF, even when RNA synthesis is blocked. Several minutes after the initiation of a concentration gradient of NGF from a micropipette in the vicinity of PC12D cells, clear projections emerged from cells on the side facing the micropipette...

journal_title：Brain research

authors： Sano M,Iwanaga M

更新日期：1994-09-05 00:00:00

abstract：:The effects of systemically administered interleukin-1beta (1.0 microg) on in vivo variations of monoamines was assessed in several brain regions. Administration of the cytokine provoked a modest increase of extracellular 5-HIAA and HVA from the nucleus accumbens, and 5-HIAA from the hippocampus. Following mild neurog...

journal_title：Brain research

authors： Merali Z,Lacosta S,Anisman H

更新日期：1997-07-04 00:00:00

abstract：:Calbindin D28k (CaBP)-containing splanchnic and cutaneous sensory neurons in the rat dorsal root ganglia (DRGs) were investigated immunocytochemically in combination with a fluorescent dye tracer (Fluoro gold). About 15% of the DRG neurons at Th9-10 levels showed CaBP-like immunoreactivity. Eighty-four % of the splanc...

journal_title：Brain research

authors： Kashiba H,Senba E,Ueda Y,Tohyama M

更新日期：1990-10-01 00:00:00

abstract：:There is evidence that acute exposure to kainic acid (KA) induces the release of endogenous ligands for opioid receptors and that mu-opioid agonists intensify KA-induced neurodegeneration. The aim of the present study was to investigate any acute toxic effects of KA upon mu-opioid receptors labelled with [3H]-DAMGO. 2...

journal_title：Brain research

authors： Ridd MJ,Fosbraey P,Kitchen I

更新日期：1998-12-14 00:00:00

abstract：:We examined the effects of nicotinic drugs on the metabolites of [3H]dopamine (DA) released from rat striatal synaptosomes in comparison with the effects of high K+ and methamphetamine stimulation. The pattern of outflow of [3H]DA and its metabolites induced by nicotine stimulants, acetylcholine (ACh), nicotine and lo...

journal_title：Brain research

authors： Takano Y,Sakurai Y,Kohjimoto Y,Honda K,Kamiya HO

更新日期：1983-11-21 00:00:00

abstract：:Trigeminal hyperalgesia frequently appears in diabetic neuralgia altering the transmission of orofacial sensory information. This study was designed to explore the effects of trigeminal hyperalgesia in streptozotocin-induced diabetes monitoring the expression of nitric oxide synthase in the trigeminal ganglion cells. ...

journal_title：Brain research

authors： Rodella L,Rezzani R,Corsetti G,Bianchi R

更新日期：2000-05-19 00:00:00

abstract：:Excitotoxic neuronal death underlies many neurodegenerative disorders. Because cannabinoid receptor agonists act presynaptically to inhibit glutamate release, we examined the effects of Win 55212-2, a full agonist at CB(1) receptors, and Delta(9)-tetrahydrocannabinol (THC), a partial agonist, on the survival of neuron...

journal_title：Brain research

authors： Gilbert GL,Kim HJ,Waataja JJ,Thayer SA

更新日期：2007-01-12 00:00:00

abstract：:This EEG study (N=33) examined event-related potentials associated with conflict between activated responses in the Stroop task, in order to examine the conflict monitoring theory of cognitive control, which predicts the strength of exerted control to be proportional to the detected level of conflict. However, existin...

journal_title：Brain research

authors： Chuderski A,Senderecka M,Kałamała P,Kroczek B,Ociepka M

更新日期：2016-11-01 00:00:00

abstract：:Previous studies have shown that chronic morphine increases levels of the G-protein subunits Gia and Goa, adenylate cyclase, cyclic AMP-dependent protein kinase, and certain phosphoproteins in the rat locus coeruleus, but not in several other brain regions studied, and that chronic morphine decreases levels of Gia and...

journal_title：Brain research

authors： Terwilliger RZ,Beitner-Johnson D,Sevarino KA,Crain SM,Nestler EJ

更新日期：1991-05-10 00:00:00

abstract：:After transplantation of autologous sciatic nerve segments into the retina of adult hamsters for 1-2 months, retrograde labelling with horseradish peroxidase demonstrated a population of ganglion cells situated peripheral to the graft. If an additional lesion was placed between the insertion of the graft and the optic...

journal_title：Brain research

authors： So KF,Xiao YM,Diao YC

更新日期：1986-07-02 00:00:00

abstract：:The distribution of inositol 1,4,5-trisphosphate (InsP3) 3-kinase was studied in the adult rat brain, using polyclonal antibodies raised against the purified 50,000-Da rat brain enzyme by immunohistochemistry and Western blot, in addition to enzymatic assay. Immunohistochemically, the enzyme was detected in neurons, w...

journal_title：Brain research

authors： Mailleux P,Takazawa K,Erneux C,Vanderhaeghen JJ

更新日期：1991-01-25 00:00:00

abstract：:Until now, there has been no effective therapy for chronic sensorineural hearing impairment. This study investigated the role of bone marrow cells (BMCs) in cochlear dysfunction. BALB/c mice (2 months of age), a non-presbycusis-prone mouse strain, were lethally irradiated and then transplanted with BMCs from SAMP1 mic...

journal_title：Brain research

authors： Baba S,Iwai H,Inaba M,Kawamoto K,Omae M,Yamashita T,Ikehara S

更新日期：2006-11-20 00:00:00

abstract：:Instructions are an inextricable, yet poorly understood aspect of modern human life. In this paper we propose that instruction implementation and following can be understood as fast Hebbian learning in prefrontal cortex, which trains slower pathways (e.g., cortical-basal ganglia pathways). We present a computational m...

journal_title：Brain research

authors： Ramamoorthy A,Verguts T

更新日期：2012-02-23 00:00:00

abstract：:For the evaluation of glutamatergic and GABAergic transmission during seizures, rat hippocampal CA1 and CA3 areas were separately assessed by brain microdialysis, and extracelluar glutamate and GABA were measured through the course of the seizures after a systemic administration of kainic acid (KA). The generalized co...

journal_title：Brain research

authors： Ding R,Asada H,Obata K

更新日期：1998-07-27 00:00:00

abstract：:The CNP neuropeptides (Command Neuron Peptides) were first found in the command neurons for withdrawal behavior in the terrestrial snail. Given the fact that certain peptides can be found in various invertebrates, we examined Drosophila brains to determine if CNP-like peptides were present. Two types of antisera were ...

journal_title：Brain research

authors： Ierusalimsky VN,Balaban PM

更新日期：2007-06-04 00:00:00

abstract：:MPTP is a neurotoxin thought to damage dopaminergic neurons through free radical formation. MPTP is metabolized in the brain to MPP(+), which is taken up into dopaminergic neurons via the dopamine transporter and assumed to impair mitochondrial function. We used striatal synaptosomes and telencephalic mitochondria to ...

journal_title：Brain research

authors： Fonck C,Baudry M

更新日期：2003-06-13 00:00:00

abstract：:Studies using phorbol esters imply that hippocampal Ca2+ channels are regulated by protein kinase C (PKC); however concerns have been raised because in some circumstances phorbol esters have non-specific effects on ion channels. We have tested the hypothesis that PKC modulates Ca2+ channel activity in hippocampal neur...

journal_title：Brain research

authors： Doerner D,Alger BE

更新日期：1992-11-27 00:00:00