Role of medial forebrain bundle catecholaminergic fibers in the modulation of glucocorticoid negative feedback effects.

abstract：:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) causes a disruption of nigrostriatal dopaminergic function which resembles parkinsonism. On the cellular level, the disruption involves a Ca2+ independent release of dopamine, depletion of nigral and striatal dopamine, and the death of dopaminergic neurons. We have p...

journal_title：Brain research

authors： Wilson JA,Lau YS,Gleeson JG,Wilson JS

更新日期：1991-02-15 00:00:00

abstract：:Time-course expression of Bax and Bcl-2 proteins, identified as apoptosis-regulating molecules, was assessed in gerbil hippocampus following transient forebrain ischemia. Brain sections from animals sacrificed at 48, 72, 96 h and 7 days following 5 min ischemia were immunohistochemically evaluated using polyclonal ant...

journal_title：Brain research

authors： Hara A,Iwai T,Niwa M,Uematsu T,Yoshimi N,Tanaka T,Mori H

更新日期：1996-03-04 00:00:00

abstract：:Auditory stimulation has been shown to increase REM sleep periods in cats and humans. This effect has been attributed to an elevation of the level of excitability in a variety of brain stem neuronal groups. Fos-like immunostaining (FLI) has been useful in constructing maps of post-synaptic neuronal activity with singl...

journal_title：Brain research

authors： Merchant-Nancy H,Vázquez J,Aguilar-Roblero R,Drucker-Colín R

更新日期：1992-05-08 00:00:00

abstract：:Long-term exposure to different antidepressant treatments induces increased motor response to central stimulants, due to a selective supersensitivity of dopamine D2 receptors in the limbic areas. Such an effect is accompanied by down-regulation of dopamine D1 receptor number, and by a decreased response of adenylyl cy...

journal_title：Brain research

authors： De Montis MG,Gambarana C,Meloni D,Taddei I,Tagliamonte A

更新日期：1993-03-19 00:00:00

abstract：:Frequency modulation (FM) is an important building block of complex sounds that include speech signals. Exploring the neural mechanisms of FM coding with computer modeling could help understand how speech sounds are processed in the brain. Here, we modeled the single unit responses of auditory neurons recorded from th...

journal_title：Brain research

authors： Chang TR,Chiu TW,Sun X,Poon PW

更新日期：2013-11-06 00:00:00

abstract：:Aquaporin-4 (AQP4), the prominent water channel in the brain, is particularly concentrated in astrocytic endfeet membranes lining the capillaries and the pia. This localisation pattern makes it well suited to regulate the flow of water and the homeostasis of the interstitial fluid surrounding the neurons. Using immuno...

journal_title：Brain research

authors： Medici V,Frassoni C,Tassi L,Spreafico R,Garbelli R

更新日期：2011-01-07 00:00:00

abstract：:Emotional events are preferentially retained in episodic memory. This effect is commonly attributed to enhanced consolidation and has been linked specifically to rapid eye movement (REM) sleep physiology. While several studies have demonstrated an enhancing effect of REM sleep on emotional item memory, it has not been...

journal_title：Brain research

authors： Sopp MR,Michael T,Mecklinger A

更新日期：2018-11-01 00:00:00

abstract：:Ischemic insults affecting the internal capsule result in sensory-motor disabilities which adversely affect the patient's life. Cerebral endothelial cells have been reported to exert a protective effect against brain damage, so the transplantation of healthy endothelial cells might have a beneficial effect on the outc...

journal_title：Brain research

authors： Puentes S,Kurachi M,Shibasaki K,Naruse M,Yoshimoto Y,Mikuni M,Imai H,Ishizaki Y

更新日期：2012-08-21 00:00:00

abstract：:This study examines possible changes in energy demands by developing neural crest cells in vitro using cytochrome oxidase (C.O.) histochemistry and immunohistochemical labeling of adrenergic (autonomic) cells and primary sensory neurons. Cytochrome oxidase is a key enzyme for oxidative metabolism and energy production...

journal_title：Brain research

authors： Liu S,Wilcox DA,Sieber-Blum M,Wong-Riley M

更新日期：1990-12-10 00:00:00

abstract：:We observed chronological changes of platelet endothelial cell adhesion molecule-1 (PECAM-1), final mediator of neutrophil transendothelial migration, immunoreactivity, and protein level in the gerbil hippocampus proper after 5 min of transient ischemia. One day after ischemic insult, PECAM-1 immunoreactivity and prot...

journal_title：Brain research

authors： Hwang IK,Kim DW,Yoo KY,Jung BK,Song JH,Jung JY,Choi SY,Kang TC,Lee JY,Kwon YG,Won MH

更新日期：2005-06-28 00:00:00

abstract：:The effects of continuous clonidine infusion (10 micrograms/kg/h for 10 days) and the cessation of this infusion on the circadian body temperature rhythm of the spontaneously hypertensive (SH) rat were examined. This circadian rhythm was blunted significantly during the infusion of clonidine. The fall in body temperat...

journal_title：Brain research

authors： Lewis SJ,Maccarrone C,Jarrott B

更新日期：1986-10-22 00:00:00

abstract：:We have previously shown that systemic administration of ondansetron, a selective serotonin type-3 (5-HT3) receptor antagonist, attenuates cholecystokinin (CCK)-induced suppression of food intake. The exact location of 5-HT3 receptors mediating this action is not clear and may involve hindbrain 5-HT3 receptors. In thi...

journal_title：Brain research

authors： Hayes MR,Covasa M

更新日期：2006-08-04 00:00:00

abstract：:Met-enkephalin immunoreactive material content was found to be decreased in the cervical and thoracic segments of the spinal cord from rats aged 25 months as compared to young, 3-month-old, rats. No age-related variations were detectable at the lumbar level. Bio-Gel P 30 column chromatography of thoracic segment extra...

journal_title：Brain research

authors： Missale C,Govoni S,Castelletti L,Spano PF,Trabucchi M

更新日期：1983-02-28 00:00:00

abstract：:Calbindin D28k (CaBP)-containing splanchnic and cutaneous sensory neurons in the rat dorsal root ganglia (DRGs) were investigated immunocytochemically in combination with a fluorescent dye tracer (Fluoro gold). About 15% of the DRG neurons at Th9-10 levels showed CaBP-like immunoreactivity. Eighty-four % of the splanc...

journal_title：Brain research

authors： Kashiba H,Senba E,Ueda Y,Tohyama M

更新日期：1990-10-01 00:00:00

abstract：:Oxygen therapy (OT) with hyperbaric oxygen (HBO) or normobaric hyperoxia (NBO) improves the oxygenation of penumbral tissue in experimental ischemic stroke. However, whether this results in the improvement of energy metabolism is unclear. We investigated the effect of both OTs on tissue acidosis and on ATP production....

journal_title：Brain research

authors： Sun L,Strelow H,Mies G,Veltkamp R

更新日期：2011-09-30 00:00:00

abstract：:Physical activity has been proposed as a behavior intervention that promotes mental health and some of the benefits induced by exercise have been related to the glutamatergic system. Indeed, glutamate is the most abundant excitatory neurotransmitter in brain. Thus, we evaluated if voluntary exercise in mice could modu...

journal_title：Brain research

authors： Dietrich MO,Mantese CE,Porciuncula LO,Ghisleni G,Vinade L,Souza DO,Portela LV

更新日期：2005-12-14 00:00:00

abstract：:The main purpose of the present study was to determine whether specific lymphokines may be neurotrophic, by testing their effects on the survival of hippocampal neuronal cultures. Previous studies have shown that a variety of interleukins may be neurotrophic or neurotoxic, depending upon the culture conditions, as wel...

journal_title：Brain research

authors： Araujo DM,Cotman CW

更新日期：1993-01-08 00:00:00

abstract：:In the present study, the light responses of ganglion cells to chromatic stimulus were recorded from isolated retina of neonatal chick. It was found that for some non-color-opponent ganglion cells, the spatiotemporal patterns of the cells' light responses were related to the chromatic information that they received. W...

journal_title：Brain research

authors： Zhou Y,Chen AH,Gong HQ,Liang PJ

更新日期：2005-10-12 00:00:00

abstract：:The effect of intrathecal (i.t.) galanin (GAL) on the prolonged increase of spinal reflex excitability produced by conditioning stimulation (CS) of unmyelinated muscle afferents was studied in decerebrate, spinalized, unanesthetized rats. A CS train (1 Hz, 20 s) applied to the unmyelinated fibers in the gastrocnemius ...

journal_title：Brain research

authors： Xu XJ,Wiesenfeld-Hallin Z,Hökfelt T

更新日期：1991-02-15 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) of the anterior hypothalamus is implicated in the temporal organization of circadian rhythms in a variety of physiological, endocrine and behavioral processes. There is a great deal of evidence indicating that aging is characterized by a progressive deterioration of circadian timekeep...

journal_title：Brain research

authors： Hofman MA,Swaab DF

更新日期：1994-07-18 00:00:00

abstract：:"Dystrophic' mice of the 129/ReJ-Dy strain have a genetic defect affecting Schwann cell proliferation. Spinal nerve roots of these animals contain myelinated and unmyelinated axons in addition to groups of large "amyelinated' axons. In affected regions of the spinal roots, myelinated axons are missing their myelin she...

journal_title：Brain research

authors： Wiley-Livingston CA,Ellisman MH

更新日期：1981-11-09 00:00:00

abstract：:The activity of single dopaminergic (DA) neurons (total n = 77) in the midbrain of awake, unrestrained rats was examined. The firing rates and patterns of ventral tegmental area (A10) cells (n = 39) were similar to those of identified DA neurons in anesthetized and paralyzed rats. Unit activity was briefly stimulated ...

journal_title：Brain research

authors： Freeman AS,Bunney BS

更新日期：1987-03-03 00:00:00

abstract：:The analgesic effect and its mechanism of electroacupuncture (EA) on inflammatory pain, especially in the rat model of collagen-induced arthritis (CIA), have not yet been studied. This study was designed to investigate the analgesic effect and its cholinergic and serotonergic mechanism of EA in the CIA rat model. To i...

journal_title：Brain research

authors： Baek YH,Choi DY,Yang HI,Park DS

更新日期：2005-09-28 00:00:00

abstract：:It is well known that locus coeruleus (LC) of the rat shows intense mu-opioid receptor-like immunoreactivity (MOR-LI). In the course of our study on the distribution of MOR-LI in the brain of the Japanese monkey (Macaca fuscata), however, no MOR-LI was found in the LC although the distribution pattern of MOR-LI in oth...

journal_title：Brain research

authors： Chen J,Koyama N,Kaneko T,Mizuno N

更新日期：1997-05-02 00:00:00

abstract：:The efficacy of 5 alpha-androstane-3 alpha,17 beta-diol (3 alpha-Androstanediol; 3 alpha-Diol) and 4-pregnen-3,20-dione (progesterone; P) in promoting analgesia was investigated. Ovariectomized rats received daily injections of 3 alpha-Diol (0.6, 3.0, 6.0 and 7.5 mg/kg) or vehicle and twice daily injections of estradi...

journal_title：Brain research

authors： Frye CA,Van Keuren KR,Rao PN,Erskine MS

更新日期：1996-02-12 00:00:00

abstract：:Hypoxia markedly depresses synaptic transmission in hippocampal slices of the rat. This depression is attributed to presynaptic inhibition of glutamate release and is largely mediated by adenosine released during hypoxia acting through presynaptic adenosine A(1) receptors. Paired pulse facilitation studies allowed us ...

journal_title：Brain research

authors： Coelho JE,de Mendonça A,Ribeiro JA

更新日期：2000-06-30 00:00:00

abstract：:The genomic response following brain ischemia is very complex and involves activation of both protective and detrimental signaling pathways. Immediate early genes (IEGs) represent the first wave of gene expression following ischemia and are induced in extensive regions of the ischemic brain including cerebral cortex a...

journal_title：Brain research

authors： Rickhag M,Teilum M,Wieloch T

更新日期：2007-06-02 00:00:00

abstract：:Subcutaneous administration of rotenone has recently attracted attention because of its convenience, simplicity and efficacy in replicating features of Parkinson's disease (PD) in animal models. However, the wide range of doses reported in the literature makes it difficult to evaluate the effectiveness of this techniq...

journal_title：Brain research

authors： Zhang ZN,Zhang JS,Xiang J,Yu ZH,Zhang W,Cai M,Li XT,Wu T,Li WW,Cai DF

更新日期：2017-01-15 00:00:00

abstract：:The subfornical organ, along with other regions of the lamina terminalis, may contain osmoreceptors and is likely to be a site of action of blood-borne angiotensin II. The neural pathways by which these stimuli lead to vasopressin secretion, have been suggested to extend from the subfornical organ to hypothalamic site...

journal_title：Brain research

authors： Oldfield BJ,Hards DK,McKinley MJ

更新日期：1991-08-30 00:00:00

abstract：:Using quantitative receptor radioautography, binding sites for the 'peripheral-type' benzodiazepine receptor ligand [3H]PK 11195 were studied in rats 4 week after end-to-side portacaval anastomosis and in sham-operated controls. Portacaval anastomosis resulted in region-selective increases in density of [3H]PK 11195 b...

journal_title：Brain research

authors： Giguère JF,Hamel E,Butterworth RF

更新日期：1992-07-10 00:00:00