Abstract：
:Auditory stimulation has been shown to increase REM sleep periods in cats and humans. This effect has been attributed to an elevation of the level of excitability in a variety of brain stem neuronal groups. Fos-like immunostaining (FLI) has been useful in constructing maps of post-synaptic neuronal activity with single cell resolution, and has been suggested to be tightly correlated with ongoing neuronal activity. This study used FLI to quantify neurons from structures expressing c-fos in brain stem areas in animals with normal REMs and compared them with those showing extended REM periods. The results basically indicated that brain stem areas which in other studies have been described as having REM-ON cells, showed an increase in FLI, while no FLI changes occurred in areas described as having REM-OFF cells. These results are discussed in terms of the possibility that REM maintenance is related to a widespread increase in brain stem excitability.
journal_name
Brain Resjournal_title
Brain researchauthors
Merchant-Nancy H,Vázquez J,Aguilar-Roblero R,Drucker-Colín Rdoi
10.1016/0006-8993(92)90072-hsubject
Has Abstractpub_date
1992-05-08 00:00:00pages
342-6issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(92)90072-Hjournal_volume
579pub_type
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