Hepatoma in siblings with progressive familial cholestatic cirrhosis of childhood.

abstract：:To investigate the effect of matrix-degrading enzymes on the malignant potential of oral squamous cell carcinoma, the expression of matrix metalloproteinase-2 (MMP-2/72-kD gelatinase/type IV collagenase) in 46 patients who had neck surgery for oral cancer was studied immunohistochemically. In 20 of 26 patients (76.9%)...

journal_title：American journal of clinical pathology

authors： Kusukawa J,Sasaguri Y,Shima I,Kameyama T,Morimatsu M

更新日期：1993-01-01 00:00:00

abstract：:Following normalization of blood glucose levels, a marked change in the MCV and in the calculated hematocrit was observed in five patients with transient severe hyperglycemia. The addition of varied concentrations of glucose to blood samples from healthy volunteers and from patients with microcytic, macrocytic, and no...

journal_title：American journal of clinical pathology

authors： Holt JT,DeWandler MJ,Arvan DA

更新日期：1982-05-01 00:00:00

abstract：:The ATHENA (Addressing THE Need for Advanced HPV Diagnostics) HPV study evaluated the clinical usefulness of the cobas HPV Test (Roche Molecular Systems, Pleasanton, CA) for high-risk human papillomavirus (HR-HPV) testing (14 HR types) and individual HPV-16/HPV-18 genotyping in women undergoing routine cervical cytolo...

journal_title：American journal of clinical pathology

authors： Wright TC Jr,Stoler MH,Sharma A,Zhang G,Behrens C,Wright TL,ATHENA (Addressing THE Need for Advanced HPV Diagnostics) Study Group.

更新日期：2011-10-01 00:00:00

abstract：:Considerable progress has been achieved in our knowledge of the function of the chemokine system and in understanding its role in the pathophysiology of human diseases. This complex system, presently including approximately 50 cytokines and 20 receptors, coordinates leukocyte recruitment in a variety of human diseases...

journal_title：American journal of clinical pathology

authors： Locati M,Bonecchi R,Corsi MM

更新日期：2005-06-01 00:00:00

abstract：:The authors report the use of cardiac troponin I (cTnI) for the early, noninvasive determination of coronary reperfusion following thrombolytic therapy. Cardiac troponin I, creatine kinase (CK)-MB, and myoglobin concentrations were measured in early serum specimens at 30, 60, and 90 minutes after initiation of therapy...

journal_title：American journal of clinical pathology

authors： Apple FS,Henry TD,Berger CR,Landt YA

更新日期：1996-01-01 00:00:00

abstract：:Pseudomonas aeruginosa is a frequent and virulent pulmonary pathogen in patients with cystic fibrosis. If colonization is not prevented, P aeruginosa becomes permanently established and nearly always mutates into a mucoid strain. The alginate-containing matrix of the mucoid strain is thought to allow the formation of ...

journal_title：American journal of clinical pathology

authors： Pritt B,O'Brien L,Winn W

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVES:To evaluate the expression of progesterone receptor (PR), estrogen receptor (ER), and G protein-coupled estrogen receptor 1 (GPER-1) in cutaneous neurofibromas (cNFs) and their correlation with demographic, clinical, and laboratory data of individuals with neurofibromatosis 1 (NF1). The association of PROGIN...

journal_title：American journal of clinical pathology

authors： Rozza-de-Menezes RE,Almeida LM,Andrade-Losso RM,de Souza Vieira G,Siqueira OHK,Brum CI,Riccardi VM,Cunha KS

更新日期：2020-12-08 00:00:00

abstract：:p53 protein expression was evaluated in a series of 204 primary colorectal adenocarcinomas by immunohistochemistry using frozen tissue sections and monoclonal antibody DO-7. Nuclear staining of more than 5% of neoplastic cells was observed in 124 (60.8%) adenocarcinomas, which were classified as p53 positive. p53 immu...

journal_title：American journal of clinical pathology

authors： Lanza G Jr,Maestri I,Dubini A,Gafa R,Santini A,Ferretti S,Cavazzini L

更新日期：1996-05-01 00:00:00

abstract：:A fatal case of an apparently congenital form of hemophagocytic reticulosis is reported. The onset was manifested by hyperbilirubinemia and hepatosplenomegaly which were present at birth and persisted throughout life. Fever, anemia and pancytopenia developed at 1 month of age and became progressively worse. A splenect...

journal_title：American journal of clinical pathology

authors： Koto A,Morecki R,Santorineou M

更新日期：1976-04-01 00:00:00

abstract：OBJECTIVES:Overuse of laboratory tests is a persistent issue. We examined the use and overuse of serum immunofixation electrophoresis and serum free light chain assays to develop an algorithm for optimizing utilization. METHODS:A retrospective review of all tests, for investigation of monoclonal gammopathies, for all ...

journal_title：American journal of clinical pathology

authors： Heaton C,Vyas SG,Singh G

更新日期：2016-04-01 00:00:00

abstract：:To improve the positive predictive value (PPV) for high-risk human papillomavirus (HR-HPV) in primary screening, DNA ploidy was measured on the same liquid-based sample by image cytometry in 984 cases showing discrepancies between cytology and HR-HPV testing. Of the conflicting results, 14.5% corresponded to a cytolog...

journal_title：American journal of clinical pathology

authors： Lorenzato M,Bory JP,Cucherousset J,Nou JM,Bouttens D,Thil C,Dez F,Evrard G,Quereux C,Birembaut P,Clavel C

更新日期：2002-11-01 00:00:00

abstract：:Intrauterine clostridial infections have historically been associated with puerperal sepsis, often subsequent to instrumented abortions. Isolated reports have been associated with a malignant neoplasm or degenerating leiomyoma, most often after instrumentation, radiation therapy, or chemotherapy. In these cases, well-...

journal_title：American journal of clinical pathology

authors： Hogan SF,Ireland K

更新日期：1989-01-01 00:00:00

abstract：:We sought to determine whether a group of cases that was relatively high in disagreements and subsequent amendments could be identified and targeted for blinded review. During a 4-year period, 8,916 surgical pathology and nongynecologic cytology cases were subjected to blinded review; of these, there were 616 disagree...

journal_title：American journal of clinical pathology

authors： Renshaw AA,Gould EW

更新日期：2006-11-01 00:00:00

abstract：:We determined whether there were additional diagnostic findings in additional level sections performed on polyps with no pathologic diagnosis (NPD) or those in which only lymphoid aggregates (LAs) were seen initially and determined the level at which findings were identified. All colorectal biopsy specimens submitted ...

journal_title：American journal of clinical pathology

authors： Nash JW,Niemann T,Marsh WL,Frankel WL

更新日期：2002-03-01 00:00:00

abstract：:The May-Hegglin anomaly is one of the rare forms of heriditary thrombocytopenia. Since fewer than 100 cases of May-Hegglin anomaly have been described to date, major controversies regarding the adequacy of hemostasis in vivo and abnormalities of platelet function in vitro continue to prevail. This report describes the...

journal_title：American journal of clinical pathology

authors： Hamilton RW,Shaikh BS,Ottie JN,Storch AE,Saleem A,White JG

更新日期：1980-11-01 00:00:00

abstract：:A population-based case-control study of college students was undertaken to estimate the effect of a positive clinical test for human papillomavirus (HPV) DNA (the Virapap test) on the rate of squamous intraepithelial lesions (SIL) of the uterine cervix. When age, multiple lifetime sexual partners, and oral contracept...

journal_title：American journal of clinical pathology

authors： Levine AJ,Harper J,Hilborne L,Rosenthal DL,Weismeier E,Haile RW

更新日期：1993-07-01 00:00:00

abstract：:The authors analyzed the frequency of immunophenotypic abnormalities in 1,474 cases of routinely fixed, paraffin-embedded B-lineage non-Hodgkin's lymphomas. B-lineage was determined by immunoreactivity for CD20 (L26, 92%); CD45RA (4KB5, an additional 3%) or immunoglobulin (Ig) light chain restriction (remaining 5%). C...

journal_title：American journal of clinical pathology

authors： Gelb AB,Rouse RV,Dorfman RF,Warnke RA

更新日期：1994-12-01 00:00:00

abstract：:The aim of the present study was to determine whether micromorphometric features of positive sentinel lymph nodes (SLNs) from patients with melanoma are useful for predicting further nodal involvement in completion lymph node dissection (CLND) specimens. Of 986 patients with melanoma undergoing SLN biopsy between Marc...

journal_title：American journal of clinical pathology

authors： Scolyer RA,Li LX,McCarthy SW,Shaw HM,Stretch JR,Sharma R,Thompson JF

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVES:The objective of this research was to determine test intervals between intraoperator case reviews to minimize the impact of recall. METHODS:Three pathologists were presented with a group of 120 slides and subsequently challenged with a study set of 120 slides after 2-week and 4-week intervals. The challenge...

journal_title：American journal of clinical pathology

authors： Campbell WS,Talmon GA,Foster KW,Baker JJ,Smith LM,Hinrichs SH

更新日期：2015-03-01 00:00:00

abstract：:Mantle cell lymphoma (MCL) expresses pan-B-cell antigens and is usually CD5+/CD10-/CD23-/FMC7+. In this study, we evaluated 52 patients with confirmed diagnoses of MCL and identified variant immunophenotypes in 21 patients (19/48 classical and 2/4 variant MCLs), including CD5- in 6 (12%) of 52, CD10+ in 4 (8%) of 50, ...

journal_title：American journal of clinical pathology

authors： Gao J,Peterson L,Nelson B,Goolsby C,Chen YH

更新日期：2009-11-01 00:00:00

abstract：:Neoplastic transformation of epithelial cell sis commonly associated with altered synthesis of mucin glycoproteins. Few studies have been performed on the correlation between MUC 1 expression and pancreatic carcinoma using immunohistochemical methods. We compared the patterns of MUC 1 expression in normal pancreatic t...

journal_title：American journal of clinical pathology

authors： Monges GM,Mathoulin-Portier MP,Acres RB,Houvenaeghel GF,Giovannini MF,Seitz JF,Bardou VJ,Payan MJ,Olive D

更新日期：1999-11-01 00:00:00

abstract：:Urine cultures represent 40-50% of specimens processed by hospital clinical microbiology laboratories. An accurate rapid screening method to detect positive urine cultures could greatly improve laboratory efficiency. Three hundred eighty-two unselected urines were screened by nephelometry at 2, 4, and 5 hours of shaki...

journal_title：American journal of clinical pathology

authors： Heinz T,Pezzlo M,Thrupp L

更新日期：1982-03-01 00:00:00

abstract：:Two unusual cases of acute lymphoblastic leukemia-hand mirror variant (ALL-HMV) are presented. One patient demonstrated a mixed immunophenotype with HLA-DR, My7, transferrin receptor surface markers, and terminal deoxynucleotidyl transferase positivity. To the authors' knowledge, this is the first ALL-HMV reported wit...

journal_title：American journal of clinical pathology

authors： Schumacher HR,Desai SN,McClain KL,Domenico DR,Dizikes GJ,Bird ML

更新日期：1989-04-01 00:00:00

abstract：:Proliferative lesions, which include collagen, elastic fibers and abnormally oriented muscle fibers, were found to develop in intramyocardial arteries more rapidly with age in cigarette smokers than in nonsmokers. The study attempted to determine whether these lesions reduce perfusion pressures in the subendocardial z...

journal_title：American journal of clinical pathology

authors： Naeye RL,Truong LD

更新日期：1977-10-01 00:00:00

abstract：:In 42 patients with locally advanced breast cancer treated with neoadjuvant chemotherapy followed by surgery and radiation therapy, the effects of chemotherapy on tumor architecture, morphometric nuclear and nucleolar characteristics, DNA ploidy, proliferation index measured by mitotic activity index, expression of di...

journal_title：American journal of clinical pathology

authors： Honkoop AH,Pinedo HM,De Jong JS,Verheul HM,Linn SC,Hoekman K,Wagstaff J,van Diest PJ

更新日期：1997-02-01 00:00:00

abstract：:Blood glucose results for 2,601 specimens obtained at multiphasic health examination, divided into three age groups, were analyzed using probability plot paper. Two straight lines could be fitted to each distribution. The assumption was made that the lower lines correspond to "normal-healthy" persons, whereas the uppe...

journal_title：American journal of clinical pathology

authors： Morgenstern NL,Shearn MA

更新日期：1981-08-01 00:00:00

abstract：:Previous studies suggest that low prostate weight is a significant negative prognostic factor for prostate cancer. In the current study, the data for 431 men who underwent radical retropubic prostatectomy between 1990 and 1998 were analyzed for association between prostate weight and various clinical and pathologic pa...

journal_title：American journal of clinical pathology

authors： Davidson DD,Koch MO,Lin H,Jones TD,Biermann K,Cheng L

更新日期：2010-04-01 00:00:00

abstract：:Fresh open lung biopsy material from 57 patients was incubated with fluoresceinated complement and immunoglobulin antisera. An indirect immunofluorescent assay using neonatal lung as substrate was conducted as well. Direct immunofluorescent patterns could be categorized into interalveolar septal capillary deposition, ...

journal_title：American journal of clinical pathology

authors： Magro CM,Morrison C,Pope-Harman A,Rothrauff SK,Ross P Jr

更新日期：2003-02-01 00:00:00

abstract：:Little information has been reported describing antigen stability in plasma cell myeloma. In this study, the expression frequency and stability of 2 potential therapeutic targets, CD20 and CD52, along with the frequently aberrantly expressed CD56 antigen, were evaluated by flow cytometric analyses in 56 patients with ...

journal_title：American journal of clinical pathology

authors： Cao W,Goolsby CL,Nelson BP,Singhal S,Mehta J,Peterson LC

更新日期：2008-06-01 00:00:00

abstract：:It has been shown that the monoclonal antibody Ki-67 reacts with a nuclear antigen that is expressed only by proliferating cells. The feasibility of using image analysis to quantitate Ki-67 staining (proliferation index [PI]) of epithelial ovarian cancers was investigated. The PI was determined in 50 advanced-stage pr...

journal_title：American journal of clinical pathology

authors： Jordan PA,Kerns BJ,Pence JC,Kohler MF,Bast RC Jr,Kinney RB,Berchuck A

更新日期：1993-06-01 00:00:00