Micromorphometric features of positive sentinel lymph nodes predict involvement of nonsentinel nodes in patients with melanoma.

abstract：:Platelet-derived growth factors (PDGFs) exert their biologic function by binding to 3 different tyrosine kinase receptor isoforms. Especially the PDGF-alpha alpha receptor binds PDGF proteins with high specificity, which results in growth stimulation. The expression of the receptor and its ligand was studied in human ...

journal_title：American journal of clinical pathology

authors： Sulzbacher I,Birner P,Träxler M,Marberger M,Haitel A

更新日期：2003-07-01 00:00:00

abstract：:Mechanical release of single cell suspensions from solid tumors for DNA analysis by flow cytometry has been shown to be optimal for adenocarcinomas in general. In the breast, many adenocarcinomas are fibrotic or scirrhous, creating difficulty in separating the neoplastic cells from the stroma. The authors have conduct...

journal_title：American journal of clinical pathology

authors： Torres FX,Mackowiak PG,Brown RD,Linden MD,Zarbo RJ

更新日期：1995-01-01 00:00:00

abstract：:A method using the RNA polymerase chain reaction technique to diagnose infection retrospectively using single-stranded RNA enteroviruses in paraffin-embedded tissue blocks is reported. This method takes advantage of extreme sequence conservation in the 5' untranslated region of the enteroviral genome and uses two roun...

journal_title：American journal of clinical pathology

authors： Redline RW,Genest DR,Tycko B

更新日期：1991-11-01 00:00:00

abstract：:A ligand assay specific for cobalamin that uses mouse stomach as the source of intrinsic factor has been developed. When mouse stomach extract incubated with radiocobalamin is fractionated by gel chromatography, the radioactive complex elutes as a single peak with apparent molecular weight of 54,900. Formation of the ...

journal_title：American journal of clinical pathology

authors： Reynoso G,Tuggey R,Hansen H,Fontelo PA,Konopka S,Miller JT

更新日期：1981-06-01 00:00:00

abstract：:We used a panel of paraffin antibodies to determine whether neoplastic and nonneoplastic lymphoid aggregates in the bone marrow can be distinguished reliably. Formalin-fixed, paraffin-embedded bone marrow core biopsy specimens with lymphoid aggregates were stained using primary antibodies directed against bcl-2, bcl-6...

journal_title：American journal of clinical pathology

authors： West RB,Warnke RA,Natkunam Y

更新日期：2002-04-01 00:00:00

abstract：:We developed anecdotal evidence that parenteral iron therapy is associated with a characteristic pattern of iron staining in bone marrow aspirate smears. In this pattern, uniform blue granules are observed within reticuloendothelial cells/stromal cells with Prussian blue staining, many times in curvilinear arrays. To ...

journal_title：American journal of clinical pathology

authors： Thomason RW,Lavelle J,Nelson D,Lin K,Uherova P

更新日期：2007-10-01 00:00:00

abstract：:To establish the feasibility of immunotyping specimens transported over great distance, the University of Arizona and the Cleveland Clinic exchanged 39 lymphoma cases (26 B-cell, 13 T-cell cases) via air express for phenotyping. They were exchanged with the use of glass slides with adherent snap-frozen sections. The m...

journal_title：American journal of clinical pathology

authors： Grogan TM,Tubbs RR

更新日期：1987-04-01 00:00:00

abstract：OBJECTIVES:To assess the frequency of systemic mastocytosis (SM) in a large series of acute myeloid leukemia (AML) with t(8;21)(q22;q22). METHODS:We retrospectively characterized 40 bone marrow aspirate smears and biopsy specimens from patients with AML with t(8;21) for the presence of SM. Cases were assessed for mast...

journal_title：American journal of clinical pathology

authors： Johnson RC,Savage NM,Chiang T,Gotlib JR,Cherry AM,Arber DA,George TI

更新日期：2013-10-01 00:00:00

abstract：:Plasma samples from patients with severe classic hemophilia, suspected of having mild inhibitors not detected in the standard Bethesda inhibitor test, were examined in modified Bethesda tests and in a screening test based on the activated partial thromboplastin time (APTT). The APTT test was more sensitive to mild inh...

journal_title：American journal of clinical pathology

authors： Ewing NP,Kasper CK

更新日期：1982-06-01 00:00:00

abstract：:Several authors have suggested that a plausible mechanism for variation in reported mean corpuscular volume (MCV) and hematocrit values for Hematology Survey Specimens may be due to the presence of hyperglycemia in the suspending matrix of the specimens, resulting in cell swelling due to an osmotic matrix effect. The ...

journal_title：American journal of clinical pathology

authors： Savage RA

更新日期：1983-10-01 00:00:00

abstract：:This, to authors' knowledge, is the first report in the United States of Tinea pedis caused by Trichophyton violaceum in a recent Southeast Asian immigrant. Because of the recent entry into this country of refugees from an area of the world where T. violaceum is endemic, this anthropophilic dermatophyte may become a s...

journal_title：American journal of clinical pathology

authors： Fusaro RM,Miller NG,Kelly D

更新日期：1983-07-01 00:00:00

abstract：:A patient receiving antihypertensive therapy developed acute intravascular hemolysis and died. Hemolysis was due to an immune process associated with antibody to thiazide. Only two other cases have been reported. Thiazide-induced hemolysis appears to be confined to those patients treated concommitantly with methyldopa...

journal_title：American journal of clinical pathology

authors： Beck ML,Cline JF,Hardman JT,Racela LS,Davis JW

更新日期：1984-06-01 00:00:00

abstract：:To compare the Affirm VPIII molecular test (Becton Dickinson, Burlington, NC) with morphologic identification used in routine Papanicolaou (Pap) test screening in the detection and identification of Candida species, Trichomonas vaginalis, and Gardnerella vaginalis, we identified 431 cases with a concomitant Pap test a...

journal_title：American journal of clinical pathology

authors： Levi AW,Harigopal M,Hui P,Schofield K,Chhieng DC

更新日期：2011-03-01 00:00:00

abstract：:An acquired circulating inhibitor to Factor VIII:C was found in a 27-year-old postpartum woman who presented with ecchymoses and hematomas. Postpartum Factor VIII:C inhibitors can clinically manifest with signs and symptoms not unlike those in a classic hemophiliac. The natural history of this inhibitor is typically o...

journal_title：American journal of clinical pathology

authors： Shitamoto BS,Leslie KO,Galloway WB

更新日期：1982-11-01 00:00:00

abstract：:In the differential diagnosis of Spitz nevus vs malignant melanoma, patient age provides a critical piece of clinical information, because Spitz nevi occur mostly in children and melanomas occur mostly in adults. Nevertheless, there is overlap in the age distributions of Spitz nevus and melanoma. The issue to consider...

journal_title：American journal of clinical pathology

authors： Vollmer RT

更新日期：2004-06-01 00:00:00

abstract：:A case of septicemia caused by Pseudomonas paucimobilis is reported. This represents the first definitive case of disease produced by this yellow-pigmented, nonfermentative bacillus. ...

journal_title：American journal of clinical pathology

authors： Slotnick IJ,Hall J,Sacks H

更新日期：1979-11-01 00:00:00

abstract：:Reported is a case of lymphoma which was preceded for nine years by an apparently reactive lymphadenopathy. Original slides of the multiple lymphoid tissue samples are reviewed, with emphasis on the gradually increasing numbers of mitoses, atypical histiocytes, and eosinophils, suggestive of malignant transformation. ...

journal_title：American journal of clinical pathology

authors： Hyland CH,Murad TM,Dismukes WE

更新日期：1977-11-01 00:00:00

abstract：:The cytopathologic findings of 196 cases of cancer of the breast were correlated with the hormonal receptor levels. The strict cytologic criteria that allow a positive diagnosis to be used as bases for definitive treatment include adequate cellularity, lack of cohesion, and nuclear abnormalities, including increased n...

journal_title：American journal of clinical pathology

authors： Kern WH

更新日期：1982-12-01 00:00:00

abstract：:Hyperparathyroidism may occasionally present as a neck mass resulting from cystic change in a parathyroid adenoma. We report an unusual instance of hyperparathyroidism presenting as a palpable, but asymptomatic hyperplastic parathyroid gland cyst. We conclude that hyperplastic parathyroid glands may undergo cystic deg...

journal_title：American journal of clinical pathology

authors： Fallon MD,Haines JW,Teitelbaum SL

更新日期：1982-01-01 00:00:00

abstract：:Clinical data and histologic sections of the liver, including immunohistochemical studies for hepatitis B surface and core antigens, were reviewed in 42 autopsy cases of the acquired immune deficiency syndrome (AIDS). Hepatomegaly, elevation of serum transaminases, and mild elevation of alkaline phosphatase were commo...

journal_title：American journal of clinical pathology

authors： Glasgow BJ,Anders K,Layfield LJ,Steinsapir KD,Gitnick GL,Lewin KJ

更新日期：1985-05-01 00:00:00

abstract：:In this study, I have estimated the percentage of tumor by visual estimate in 447 prostatectomy specimens from American Veterans Affairs patients and related this measurement to overall survival. Although percentage of tumor was significantly related to the serum prostate-specific antigen level, tumor stage, and Gleas...

journal_title：American journal of clinical pathology

authors： Vollmer RT

更新日期：2009-01-01 00:00:00

abstract：:Cytokeratin (CK) expression was studied in 22 sinonasal inverted papillomas. Columnar (respiratory) epithelium in inverted papillomas abundantly expressed CK7, CK8, CK18, and CK19. Immunoreactivity for CK5/14 and CK17 was found in basal and parabasal/suprabasal cells. Transitional (cuboidal) and squamous epithelium in...

journal_title：American journal of clinical pathology

authors： Schwerer MJ,Kraft K,Baczako K,Maier H

更新日期：2001-05-01 00:00:00

abstract：:A case of adenocarcinoma of the small bowel arising in pre-existing transmural ileitis (Crohn's disease) is reported and 28 previously reported cases are reviewed. Carcinoma associated with transmural enteritis occurs more often in the distal ileum, in younger patients, and in more males than expected from published d...

journal_title：American journal of clinical pathology

authors： Savage RA,Farmer RG,Hawk WA

更新日期：1975-02-01 00:00:00

abstract：OBJECTIVES:To assess physicians' and nurses' satisfaction with the service provided by the laboratory at Gondar University Hospital. METHODS:We conducted a cross-sectional study involving 196 nurses and physicians. RESULTS:Overall level of satisfaction was 51.1% for nurses and 51.5% for physicians. Lack of consistenc...

journal_title：American journal of clinical pathology

authors： Addis Z,Birhan W,Derseh D,Sahle B,Gizaw N

更新日期：2013-09-01 00:00:00

abstract：:We present what, to our knowledge, is the first reported case of nephrogenic metaplasia of the ureter. Nephrogenic metaplasia involves the transitional epithelium of the urinary tract and results in the formation of epithelial tubules, which are histologically similar to renal tubules. Special stains demonstrated both...

journal_title：American journal of clinical pathology

authors： Lugo M,Petersen RO,Elfenbein IB,Stein BS,Duker NJ

更新日期：1983-07-01 00:00:00

abstract：:Mycobacterium leprae causes leprosy. M leprae strains collected worldwide have been genetically clonal, which poorly explains the varying severity and clinical features of the disease. We discovered a new Mycobacterium species from 2 patients who died of diffuse lepromatous leprosy (DLL). The Mycobacterium was purifie...

journal_title：American journal of clinical pathology

authors： Han XY,Seo YH,Sizer KC,Schoberle T,May GS,Spencer JS,Li W,Nair RG

更新日期：2008-12-01 00:00:00

abstract：:The relationship between immunohistochemically measured membranous expression of erbB-2 oncoprotein and prognosis in breast cancer is controversial, and the relationship between cytoplasmic positivity and prognosis has been minimally investigated. The clinical course of 300 women with infiltrating breast carcinoma, wh...

journal_title：American journal of clinical pathology

authors： Keshgegian AA,Cnaan A

更新日期：1997-10-01 00:00:00

abstract：:Blood glucose results for 2,601 specimens obtained at multiphasic health examination, divided into three age groups, were analyzed using probability plot paper. Two straight lines could be fitted to each distribution. The assumption was made that the lower lines correspond to "normal-healthy" persons, whereas the uppe...

journal_title：American journal of clinical pathology

authors： Morgenstern NL,Shearn MA

更新日期：1981-08-01 00:00:00

abstract：:Trends in surgical practice suggest that pathologists will encounter increased numbers of patients with small invasive ductal adenocarcinomas; small, if any, metastatic deposits in axillary lymph nodes (ALNs); and possibly fewer ALN specimens to examine. New prognostic histologic features may be needed in this environ...

journal_title：American journal of clinical pathology

authors： Goldstein NS,Mani A,Vicini F,Ingold J

更新日期：1999-01-01 00:00:00

abstract：:This study focused on women who had an abnormal Papanicolaou smear and a subsequent colposcopic examination negative for a cervical squamous intraepithelial lesion. Cervical swabs obtained during the initial colposcopic examination were analyzed for human papillomavirus (HPV) DNA, and these results were correlated wit...

journal_title：American journal of clinical pathology

authors： Nuovo GJ,Moritz J,Walsh LL,MacConnell P,Koulos J

更新日期：1992-11-01 00:00:00