Carcinoma of the small intestine associated with transmural ileitis (Crohn's disease).

abstract：:Oxidant-antioxidant balance is known to regulate growth factors and invasion of tumor cells. Manganese superoxide dismutase (MnSOD), copper zinc SOD (CuZnSOD), and extracellular SOD (ECSOD), the first-line antioxidant defenses, were studied in lung carcinomas by immunohistochemical analysis (n = 139, 56, and 37, respe...

journal_title：American journal of clinical pathology

authors： Svensk AM,Soini Y,Pääkkö P,Hiravikoski P,Kinnula VL

更新日期：2004-09-01 00:00:00

abstract：:Four acid hydrolases, acid phosphatase (AP), alpha-naphthyl acetate esterase (ANAE), beta-glucuronidase, and N-acetyl-beta-glucosaminidase, were determined cytochemically in peripheral blood lymphocytes from 50 patients with B and T chronic lymphocytic and prolymphocytic leukemias (CLL, PLL) and related disorders. Str...

journal_title：American journal of clinical pathology

authors： Crockard A,Chalmers D,Matutes E,Catovsky D

更新日期：1982-10-01 00:00:00

abstract：:Our objective was to assess the loss of E-cadherin (EC) as a diagnostic marker or a predictor of prognosis. We stained 276 breast carcinomas with monoclonal antibodies to EC (invasive lobular carcinomas [ILC] and variants, 59; invasive ductal carcinoma and ductal special types [IDC], 204; tubulolobular carcinoma [TLC]...

journal_title：American journal of clinical pathology

authors： Qureshi HS,Linden MD,Divine G,Raju UB

更新日期：2006-03-01 00:00:00

abstract：Objectives:To examine the relationship between the recently defined Gleason grade groups and prostate cancer-specific mortality. Methods:If the probability of prostate cancer-specific death is symbolized as P(PSD), the probability of biochemical failure is symbolized as P(BF), and the probability of prostate cancer-sp...

journal_title：American journal of clinical pathology

authors： Vollmer RT

更新日期：2017-03-01 00:00:00

abstract：:Factor V Leiden (FVR506Q) is a genetic defect in the factor V (FV) molecule that confers resistance to proteolysis by activated protein C (APC) and is the most common abnormality detected in patients studied for hereditary thrombophilia. The initial screening test for this abnormality was a comparison of the activated...

journal_title：American journal of clinical pathology

authors： Akhtar MS,Blair AJ,King TC,Sweeney JD

更新日期：1998-04-01 00:00:00

abstract：:The clinical, light microscopic, and immunohistochemical features of 14 sinonasal malignant melanomas were studied to show their diverse morphologic appearance and distinction from therapeutically more amenable neoplasms that occur in this region. The tumors arose in 6 men and 8 women (median age, 70 years). Eleven pa...

journal_title：American journal of clinical pathology

authors： Franquemont DW,Mills SE

更新日期：1991-12-01 00:00:00

abstract：:Demonstration of prostate-specific acid phosphatase by immunologic methods in tissue sections or in plasma necessitates a monospecific antiserum. This is produced by immunizing rabbits with pure prostate-specific acid phosphatase antigen, prepared from seminal fluid. The ejaculate is centrifuged, dialyzed against a ci...

journal_title：American journal of clinical pathology

authors： de Vries GP,Slob AW,Jöbsis AC,Meijer AE,Sanders GT

更新日期：1979-12-01 00:00:00

abstract：:Carumonam, a new monobactam, was found to have an anti-microbial spectrum similar to aztreonam. Its spectrum includes Enterobacteriaceae, Haemophilus influenzae, pathogenic Neisseria species, Pseudomonas aeruginosa, and some streptococci. Staphylococcus species, enterococci, and many other nonenteric gram-negative bac...

journal_title：American journal of clinical pathology

authors： Jones RN,Barry AL,Thornsberry C,Fuchs PC,Packer RR

更新日期：1986-11-01 00:00:00

abstract：:The p63 gene, a member of the p53 family, is an epithelial marker expressed in embryonic ectoderm, breast myoepithelium, prostate, oral epithelium, epidermis, and urothelium. The DeltaN-p63 isoforms of p63, which are believed to behave as oncogenes, are expressed in squamous cell carcinoma, basal cell carcinoma, and t...

journal_title：American journal of clinical pathology

authors： Dotto J,Pelosi G,Rosai J

更新日期：2007-03-01 00:00:00

abstract：:Patients using anticoagulation point-of-care (POC) monitors are advised to periodically test these systems against laboratory methods to monitor performance. The international normalized ratio (INR), however, can vary between test systems owing to different instrument-reagent combinations. In a randomized study evalua...

journal_title：American journal of clinical pathology

authors： Sunderji R,Gin K,Shalansky K,Carter C,Chambers K,Davies C,Schwartz L,Fung A

更新日期：2005-02-01 00:00:00

abstract：:Three cases of microcystic adenomas of the pancreas with special reference to multicentric origin are described. The gross features and light microscopic findings were consistent with those described as being microcystic adenomas, but in two cases the gross examination and gelatin-embedded giant slices revealed multip...

journal_title：American journal of clinical pathology

authors： Kim YI,Seo JW,Suh JS,Lee KU,Choe KJ

更新日期：1990-08-01 00:00:00

abstract：:This study focused on women who had an abnormal Papanicolaou smear and a subsequent colposcopic examination negative for a cervical squamous intraepithelial lesion. Cervical swabs obtained during the initial colposcopic examination were analyzed for human papillomavirus (HPV) DNA, and these results were correlated wit...

journal_title：American journal of clinical pathology

authors： Nuovo GJ,Moritz J,Walsh LL,MacConnell P,Koulos J

更新日期：1992-11-01 00:00:00

abstract：:The Sysmex R-3000 (TOA Medical Electronics, Kobe, Japan) evaluates maturation of reticulocytes by quantitating the fraction of reticulocytes within low-, middle-, and high-fluorescence intensity regions. We defined the immature reticulocyte fraction (IRF) as the sum of the fraction of high-fluorescence intensity regio...

journal_title：American journal of clinical pathology

authors： Chang CC,Kass L

更新日期：1997-07-01 00:00:00

abstract：:The platelet aggregation responses induced by adenosine diphosphate (ADP) and collagen were characterized by parameters defining rate and extent of reaction. Values were compared on the basis of platelet concentration, time elapsed between sample collection and test performance, and sex of donors. Rate and extent of a...

journal_title：American journal of clinical pathology

authors： Roper P,Drewinko B,Hasler D,Johnston D,Hester J,Freireich EJ

更新日期：1979-03-01 00:00:00

abstract：:The examination of T-cell receptor (TCR) repertoires has an important role in the study of lymphoproliferative disorders and autoimmune diseases. Analysis of the complementarity-determining region 3 (CDR3) of the TCR beta chain is used to assess the clonality of T-cell populations. We developed a rapid fluorescence-ba...

journal_title：American journal of clinical pathology

authors： Lue C,Mitani Y,Crew MD,George JF,Fink LM,Schichman SA

更新日期：1999-05-01 00:00:00

abstract：:Considerable progress has been achieved in our knowledge of the function of the chemokine system and in understanding its role in the pathophysiology of human diseases. This complex system, presently including approximately 50 cytokines and 20 receptors, coordinates leukocyte recruitment in a variety of human diseases...

journal_title：American journal of clinical pathology

authors： Locati M,Bonecchi R,Corsi MM

更新日期：2005-06-01 00:00:00

abstract：:Specific esterase activity, a property generally ascribed to cells of granulocytic origin, was found in abnormal erythroid precursors obtained from the bone marrows of six patients with untreated erythroleukemia. These erythroblasts also showed nonspecific esterase activity. Neither specific nor nonspecific esterase a...

journal_title：American journal of clinical pathology

authors： Kass L

更新日期：1977-04-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to identify laboratory parameters representing erythrocyte engraftment to be used as an indicator to change the recipient to donor ABO group and Rh type following an ABO-incompatible hematopoietic stem cell transplant (HSCT). Studies have shown that ABO incompatibility does not ...

journal_title：American journal of clinical pathology

authors： Sanford K,Case N,Blake B,Michaud T,McPherson RA,Roseff SD

更新日期：2020-05-05 00:00:00

abstract：:We assessed cytologic specimens from 11 mantle cell lymphomas (MCLs) and 32 other B-cell non-Hodgkin lymphomas (NHLs) for 11q13 breakpoints using a 2-color fluorescence in situ hybridization (FISH) assay that uses an 11q13 probe centered on the CCND1 gene and a centromeric chromosome 11 probe (CEP11). The number of nu...

journal_title：American journal of clinical pathology

authors： Katz RL,Caraway NP,Gu J,Jiang F,Pasco-Miller LA,Glassman AB,Luthra R,Hayes KJ,Romaguera JE,Cabanillas FF,Medeiros LJ

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVES:To investigate metastasis associated in colon cancer 1 (MACC1) and MET expression in colorectal adenoma, Tis, early-stage invasive (T1 and T2), and advanced adenocarcinoma with liver metastasis using immunohistochemistry. METHODS:Ninety-three paraffin-embedded colorectal tumor specimens were immunohistochem...

journal_title：American journal of clinical pathology

authors： Ren B,Zakharov V,Yang Q,McMahon L,Yu J,Cao W

更新日期：2013-11-01 00:00:00

abstract：:Pathologic rupture of the spleen is a rare phenomenon in acute lymphocytic leukemia, and its mechanism is unknown. This complication has been seen almost exclusively in men, and at ages much older than those of the majority of patients who have this leukemia; these unusual features are also unexplained. A case of acut...

journal_title：American journal of clinical pathology

authors： Johnson CS,Rosen PJ,Sheehan WW

更新日期：1979-07-01 00:00:00

abstract：:A simple scheme for the speciation of clinical isolates of "viridans" streptococci based on nine physiological characteristics is presented. Use of this scheme will enable successful speciation of most "viridans" strep isolates in any laboratory and allow for the accumulation of data necessary for the definition of cl...

journal_title：American journal of clinical pathology

authors： Sands M,Sommers HM,Rubin MB

更新日期：1982-07-01 00:00:00

abstract：:Primary gastric non-Hodgkin lymphoma of mucosa-associated lymphoid tissue (MALT-NHL) is strongly related to Helicobacter pylori (H pylori) infection. CagA positive H pylori strains appear to be more aggressive, as reflected by a greater degree of gastric inflammation and higher levels of Il-8 production. Using a polym...

journal_title：American journal of clinical pathology

authors： de Jong D,van der Hulst RW,Pals G,van Dijk WC,van der Ende A,Tytgat GN,Taal BG,Boot H

更新日期：1996-11-01 00:00:00

abstract：:The authors investigated the blast cells obtained from two patients with acute myelofibrosis with the use of recently developed immunochemical and ultrastructural markers. They intended to examine the expression of megakaryoblastic, erythroblastic, myeloblastic, and monoblastic properties in these cells. Respectively,...

journal_title：American journal of clinical pathology

authors： Schreeder MT,Prchal JT,Parmley RT,Carroll AJ,Gewirtz AM,Hoffman R

更新日期：1985-01-01 00:00:00

abstract：:Thrombocytosis may reflect a primary myeloproliferative disorder or be a secondary reaction to other pathologic processes. Patients with persistent unexplained thrombocytosis meeting criteria of primary thrombocythemia had elevated levels of serum lactic dehydrogenase, whereas comparable patients with secondary thromb...

journal_title：American journal of clinical pathology

authors： Budman DR,Lackner H,Berczeller P,Silber R

更新日期：1981-06-01 00:00:00

abstract：:In situ hybridization with specific RNA radiolabeled probes was used to analyze the production of interleukin-2 (IL-2) and interferon-gamma (IFN-gamma) by 21 low-grade follicular lymphomas (FLs). All of the 21 FLs tested contained lymphokine-synthesizing cells in the interfollicular and follicular areas. Enumeration o...

journal_title：American journal of clinical pathology

authors： Peuchmaur M,Emilie D,Crevon MC,Brousse N,Gaulard P,D'Agay MF,Galanaud P,Solal-Celigny P

更新日期：1991-01-01 00:00:00

abstract：:While plasmacytosis is a common occurrence in early post-bone marrow transplantation biopsy specimens, the significance of plasma cells in such specimens from patients with multiple myeloma (MM) is unknown. We attempted to retrospectively determine, by morphologic assessment of plasma cell percentage, immunohistologic...

journal_title：American journal of clinical pathology

authors： Maia DM,Kell DL,Goates JJ,Warnke RA

更新日期：1997-06-01 00:00:00

abstract：:The purpose of our study was to improve the quality of care in an emergency department (ED) as measured by length of stay (LOS), total turnaround time (TAT) for laboratory result reporting, and the blood culture contamination rate. Data were included for patients who had at least 1 of 5 laboratory tests performed as p...

journal_title：American journal of clinical pathology

authors： Sheppard C,Franks N,Nolte F,Fantz C

更新日期：2008-10-01 00:00:00

abstract：:Members of the genus Pseudomonas are widely implicated in human disease. Although most isolates are P. aeruginosa, there have been serious outbreaks of infection with other members of the genus. The susceptibility patterns of 5) Pseudomonas isolates are reported. It was notable that of the four antibiotics tested, uni...

journal_title：American journal of clinical pathology

authors： Tilton RC,Steingrimsson O,Ryan RW

更新日期：1978-04-01 00:00:00

abstract：:This paper's purpose is to document a case of unilateral tonsillar malakoplakia. Escherichia coli was repeatedly cultured from the lesion, and the isolate was studied by expert microbiologists who found no abnormalities in its biologic properties. The course of the lesion was followed by repeated punch biopsies before...

journal_title：American journal of clinical pathology

authors： Kalfayan B,Seager GM

更新日期：1982-09-01 00:00:00