Gastric non-Hodgkin lymphomas of mucosa-associated lymphoid tissue are not associated with more aggressive Helicobacter pylori strains as identified by CagA.

Abstract:

:Primary gastric non-Hodgkin lymphoma of mucosa-associated lymphoid tissue (MALT-NHL) is strongly related to Helicobacter pylori (H pylori) infection. CagA positive H pylori strains appear to be more aggressive, as reflected by a greater degree of gastric inflammation and higher levels of Il-8 production. Using a polymerase chain reaction-based assay, cagA status was determined in H pylori strains of 12 patients with gastric MALT-NHL, 38 patients with peptic ulcer disease, and 39 patients with non-ulcer dyspepsia. CagA-positive H pylori strains were significantly more frequent in peptic ulcer disease than in non-ulcer dyspepsia (Fisher's exact test p <0.001). An increased frequency of CagA-positive strains was not identified in gastric MALT-NHL compared to non-ulcer dyspepsia patients (Fisher's exact test P <.3). Therefore, it can be concluded that infection with more aggressive strains is associated with the development of peptic ulcer disease, but plays a minor role, if any, in the development of gastric MALT-NHL.

journal_name

Am J Clin Pathol

authors

de Jong D,van der Hulst RW,Pals G,van Dijk WC,van der Ende A,Tytgat GN,Taal BG,Boot H

doi

10.1093/ajcp/106.5.670

subject

Has Abstract

pub_date

1996-11-01 00:00:00

pages

670-5

issue

5

eissn

0002-9173

issn

1943-7722

journal_volume

106

pub_type

杂志文章
  • Soft agar culture of human transitional cell carcinoma colonies from urine.

    abstract::Soft-agar culture of transitional cell carcinoma colonies from urine, bladder irrigation fluid, and transurethral resection solid tumor specimens demonstrate generally better growth of tumor cell colonies from urine than from irrigation fluid. Growth of tumor colonies from urine was adequate to evaluate presence of tu...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/78.5.690

    authors: Kirkels WJ,Pelgrim OE,Debruyne FM,Vooijs GP,Herman CJ

    更新日期:1982-11-01 00:00:00

  • Impact of Laboratory Charge Display Within the Electronic Health Record Across an Entire Academic Medical Center: Results of a Randomized Controlled Trial.

    abstract:Objectives:To determine the impact of systemwide charge display on laboratory utilization. Methods:This was a randomized controlled trial with a baseline period and an intervention period. Tests were randomized to a control arm or an active arm. The maximum allowable Medicare reimbursement rate was displayed for tests...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/ajcp/aqx110

    authors: Schmidt RL,Colbert-Getz JM,Milne CK,Vargo DJ,Hussong JW,Hoidal JR,Markewitz BA,Walker BS,Kawamoto K

    更新日期:2017-11-20 00:00:00

  • Morphologic and Immunocytochemical Features of High-Grade Serous Carcinoma of Ovary in Ascitic Fluid Effusion and Fine-Needle Aspiration Cytology.

    abstract:OBJECTIVES:High-grade serous carcinoma (HGSC) is the most common ovarian malignancy. The role of cytopathology in obtaining tissue diagnosis before institution of neoadjuvant chemotherapy (NACT) was evaluated. METHODS:All histopathology-proven HGSC specimens between 2015 and 2018 with prior cytopathologic diagnosis by...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/aqaa028

    authors: Bansal A,Srinivasan R,Rohilla M,Sundaram A,Rai B,Rajwanshi A,Suri V,Saha SC,Gupta N,Gupta P,Dey P

    更新日期:2020-06-08 00:00:00

  • Misleading hemoglobin A1c levels in a patient with paroxysmal nocturnal hemoglobinuria.

    abstract:OBJECTIVES:We report a case of a patient with diabetes mellitus and unexpectedly low hemoglobin A1c results associated with paroxysmal nocturnal hemoglobinuria (PNH). We review the impact of shortened RBC half-life on the interpretation of hemoglobin A1c levels. METHODS:Patient history and laboratory test results were...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:10.1309/AJCPTK1HPR2KULJU

    authors: Xia D,McShine R,Berg AH

    更新日期:2014-08-01 00:00:00

  • mhatomic pathology turnaround times. Use and abuse.

    abstract::Anatomic pathology service is judged by accuracy of diagnosis and rapidity of reporting of that diagnosis to clinicians. Turnaround times have been used in anatomic pathology to show how long it take to produce a tissue report. Rapid tissue diagnosis is important to patients, clinicians, administrators, and anatomic p...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:

    authors: Smith MT,Garvin AJ

    更新日期:1996-10-01 00:00:00

  • Comparison of evaluations for hormone receptors in breast carcinoma using two manual and three automated immunohistochemical assays.

    abstract::The aims of this study were to compare the quality of immunohistochemical assays of estrogen receptor (ER) and progesterone receptor (PR) and to compare the intermethod variability of assays from different manufacturers. immunohistochemical staining was entrusted to the following laboratories in Japan: Kyowa Medex, de...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/4D1A04NCDK96WFY7

    authors: Arihiro K,Umemura S,Kurosumi M,Moriya T,Oyama T,Yamashita H,Umekita Y,Komoike Y,Shimizu C,Fukushima H,Kajiwara H,Akiyama F

    更新日期:2007-03-01 00:00:00

  • Accurate Real-Time Diagnosis of Lymphoproliferative Disorders in Malawi Through Clinicopathologic Teleconferences:  A Model for Pathology Services in Sub-Saharan Africa.

    abstract:OBJECTIVES:The incidence of lymphoproliferative disorders (LPDs) is increasing in sub-Saharan Africa (SSA) due to population growth, aging, and human immunodeficiency virus (HIV). Despite significant burden, resources for diagnosis and treatment of LPDs are limited, with little infrastructure to deliver modern patholog...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/aqw118

    authors: Montgomery ND,Liomba NG,Kampani C,Krysiak R,Stanley CC,Tomoka T,Kamiza S,Dhungel BM,Gopal S,Fedoriw Y

    更新日期:2016-10-01 00:00:00

  • Papillary thyroid carcinoma with heterotopic ossification is a special subtype with extensive progression.

    abstract::An immunohistochemical study was conducted of 108 papillary carcinoma cases, including 48 cases with intratumoral heterotopic ossification (IHO). In 48 cases, papillary carcinoma with IHO was accompanied by nodular fibrosis. Cases of papillary carcinoma with IHO or nodular fibrosis showed higher incidences of lymph no...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCPQZQN50HKIAHA

    authors: Takeda M,Mikami T,Numata Y,Okamoto M,Okayasu I

    更新日期:2013-05-01 00:00:00

  • Antigenic differences among bovine and porcine Factor VIII concentrates.

    abstract::Three anti-Factor-VIII antibodies from hemophiliacs were reacted with samples of batches of Maws commerical bovine and porcine Factor VIII concentrates manufactured over a 12-year period. The apparent antibody concentrations varied widely with the different batches of concentrates. The variations are probably due to i...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/65.6.957

    authors: Edson JR,Swinehart CD

    更新日期:1976-06-01 00:00:00

  • Volumetric erythrocyte macrocytosis induced by hydroxyurea.

    abstract::An atypical form of macrocytosis termed volumetric macrocytosis is described. In contrast to the macrocyte associated with megaloblastic anemia and the pseudomacrocyte caused by viscoelastic defects, the volumetric macrocyte is characterized by an increased mean corpuscular volume and a normal cell diameter. The volum...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/85.3.337

    authors: Burns ER,Reed LJ,Wenz B

    更新日期:1986-03-01 00:00:00

  • Workload recording by microcomputer.

    abstract::Workload recording as designed by the College of American Pathologists has proven to be an invaluable aid in the assessment of overall laboratory operation. The administrative information derived from the compilation of these workload statistics is utilized to provide effective and these workload statistics is utilize...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/74.4.469

    authors: Norbut AM,Foulis PR,Mendelow H

    更新日期:1980-10-01 00:00:00

  • Non-Hodgkin's lymphoma following Hodgkin's disease. A case report and immunohistochemical corroboration.

    abstract::Two non-Hodgkin's lymphomas, one a follicular mixed cell type and the other a diffuse large cell type (Working Formulation), appeared 7 and 12 years, respectively, after the initial histopathologic diagnosis of Hodgkin's disease (nodular sclerosis) in an elderly male. The clinicopathologic implications of non-Hodgkin'...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/86.3.370

    authors: Shimizu K,Hara K,Kunii A

    更新日期:1986-09-01 00:00:00

  • Universal Mismatch Repair Protein Screening in Upper Tract Urothelial Carcinoma.

    abstract:OBJECTIVES:Universal screening of upper tract urothelial carcinoma (UTUC) for Lynch syndrome by mismatch repair (MMR) protein immunohistochemistry (IHC) has been recommended by some investigators. Herein, we assess this recommendation retrospectively by simulating its performance on a retrospective, unselected cohort o...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/aqaa100

    authors: Gayhart MG,Johnson N,Paul A,Quillin JM,Hampton LJ,Idowu MO,Smith SC

    更新日期:2020-11-04 00:00:00

  • Daily Management System of the Henry Ford Production System: QTIPS to Focus Continuous Improvements at the Level of the Work.

    abstract:OBJECTIVES:To support our Lean culture of continuous improvement, we implemented a daily management system designed so critical metrics of operational success were the focus of local teams to drive improvements. METHODS:We innovated a standardized visual daily management board composed of metric categories of Quality,...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCPLQYMOFWU31CK

    authors: Zarbo RJ,Varney RC,Copeland JR,D'Angelo R,Sharma G

    更新日期:2015-07-01 00:00:00

  • Predicting relapse of chronic myelogenous leukemia after allogeneic bone marrow transplantation by bcr-abl mRNA and DNA fingerprinting.

    abstract::Fourteen patients treated by allogeneic bone marrow transplantation for chronic myelogenous leukemia (CML) were evaluated by the polymerase chain reaction (PCR) for bcr-abl-specific transcripts. Nine patients were transplanted in the first chronic phase, three in the second chronic phase, and two in the accelerated ph...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/104.5.510

    authors: Okamoto R,Harano H,Matsuzaki M,Motomura S,Maruta A,Kodama F,Mohri H,Okubo T

    更新日期:1995-11-01 00:00:00

  • erb-b2 amplification by fluorescence in situ hybridization in breast cancer specimens read as 2+ in immunohistochemical analysis.

    abstract::We conducted this study to ascertain the prevalence of erb-b2 gene amplification in breast cancer specimens read as 2+ in immunohistochemical analysis. Slides from patients with metastatic or recurrent breast cancer were eligible for fluorescent in situ hybridization (FISH) study if they were read as 2+ immunohistoche...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/R2X4KK22QCL7PLME

    authors: Lan C,Liu JM,Liu TW,Hsu DH,Liang S,Chen JR,Peng JW

    更新日期:2005-07-01 00:00:00

  • Use of commercially prepared control sera as quality control materials for spectrophotometric bilirubin determinations in amniotic fluid.

    abstract::The visible absorption spectra of dilutions of commercially prepared chemistry control sera closely mimic those of jaundiced amniotic fluids in cases of fetal rhesus isoimmunization. The authors have assessed the use of these materials for the quality control of net absorbance measurements at 450 nm on amniotic fluids...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/84.4.513

    authors: McDonald OL,Watts MT

    更新日期:1985-10-01 00:00:00

  • Computer-assisted diagnostic surgical pathology reporting.

    abstract::A very simple method of computer-assisted reporting of surgical pathology (including gross description, microscopic description, and diagnosis) has been developed. This method is based on a modification of the existing microbiology program and files in the comprehensive MedLab Company Pathlab computer system, with the...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/78.3.337

    authors: Davey PW,Vaughan KD

    更新日期:1982-09-01 00:00:00

  • BRAF mutation status in gastrointestinal stromal tumors.

    abstract::Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors characterized by mutations of KIT or PDGFRA. The objectives of this study were to evaluate BRAF mutations in GISTs and then to correlate BRAF mutational status in the tumor with clinical parameters, with B-raf expression, and with activation of some cellul...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCPPCKGA2QGBJ1R

    authors: Hostein I,Faur N,Primois C,Boury F,Denard J,Emile JF,Bringuier PP,Scoazec JY,Coindre JM

    更新日期:2010-01-01 00:00:00

  • bcl-2 expression by multicolor flow cytometric analysis assists in the diagnosis of follicular lymphoma in lymph node and bone marrow.

    abstract::The expression of bcl-2, CD10, and CD20 was examined by multicolor flow cytometry in 78 samples including lymph node or other tissue biopsy specimens containing follicular lymphoma (FL; n = 17), reactive hyperplasia (RH; n = 28), or other malignant lymphomas (n = 20), as well as bone marrow aspirates (n = 13). The pre...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/820R-476K-Y9G0-3L9A

    authors: Cook JR,Craig FE,Swerdlow SH

    更新日期:2003-01-01 00:00:00

  • Incidental coenurosis: larval cestode presenting as an axillary mass.

    abstract::This article describes the occurrence of a coenurus, the encysted larval stage of a cestode of the genus Multiceps, within the axilla of a 40-year-old Nigerian woman. The patient had a history of intraductal carcinoma of the breast two years prior to the finding of an ipsilateral axillary mass. Pathologic evaluation o...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/80.5.735

    authors: Kurtycz DF,Alt B,Mack E

    更新日期:1983-11-01 00:00:00

  • High-risk human papillomaviruses may have an important role in non-oral habits-associated oral squamous cell carcinomas in Taiwan.

    abstract::To evaluate the etiologic role of human papillomavirus (HPV) in oral carcinogenesis, DNA samples were purified from 103 oral squamous cell carcinoma (OSCC) and 30 normal oral mucosal (NOM) specimens. A nested polymerase chain reaction, DNA sequencing, and gene-chip HPV typing were used to identify multiple HPV types i...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/C5P6-NUQ2-NW6L-CTBP

    authors: Chang JY,Lin MC,Chiang CP

    更新日期:2003-12-01 00:00:00

  • Nonuniform distribution of occult blood in feces.

    abstract::Inhibition of anti-Rh29 by erythrocytic stroma in feces was devised as a specific test for fecal occult blood. The sensitivity of this test was equivalent to that of a standard Hemoccult test, namely, 10(8) erythrocytes/g feces. Comparison of results of this test with results of Hemoccult tests of random stool specime...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/71.2.204

    authors: Rosenfield RE,Kochwa S,Kaczera Z,Maimon J

    更新日期:1979-02-01 00:00:00

  • Morphonuclear relationship between prostatic intraepithelial neoplasia and cancers as assessed by digital cell image analysis.

    abstract::Using digital cell image analysis performed on Feulgen-stained nuclei, the nuclear characteristics of prostatic neoplasia, ranging from benign (benign prostatic hyperplasia [BPH]), through dysplastic (prostatic intraepithelial neoplasia [PIN] 1-3), to carcinoma were studied. Four histopathologic groups were studied: g...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/96.5.628

    authors: Petein M,Michel P,van Velthoven R,Pasteels JL,Brawer MK,Davis JR,Nagle RB,Kiss R

    更新日期:1991-11-01 00:00:00

  • Pleomorphic adenoma (benign mixed tumor) of the breast. An immunohistochemical, flow cytometric, and ultrastructural study and review of the literature.

    abstract::Pleomorphic adenoma (or benign mixed tumor) of the breast is a rare benign neoplasm that might be misinterpreted both clinically and pathologically as a malignant tumor. The authors present an additional case of this unusual lesion studied by immunohistochemistry, electron microscopy, and flow cytometry. A 77-year-old...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:10.1093/ajcp/93.6.795

    authors: Ballance WA,Ro JY,el-Naggar AK,Grignon DJ,Ayala AG,Romsdahl MG

    更新日期:1990-06-01 00:00:00

  • Percutaneous ultrasound-guided needle biopsy of hepatic mass lesions using a cytohistologic approach. Comparison of two needle types.

    abstract::This study compared the ability to diagnose and accurately classify hepatic mass lesions by ultrasound-guided biopsy using two different needle types: a 20 gauge needle that yielded primarily cytologic material and an 18 gauge automated core biopsy needle. Slides prepared from each of the needle types were separately ...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/104.5.583

    authors: Dusenbery D,Ferris JV,Thaete FL,Carr BI

    更新日期:1995-11-01 00:00:00

  • SPLEEN/PATHOL.

    abstract::Lymphocyte subpopulations were studied in the peripheral blood, lymph nodes, and spleens in a group of 17 patients with untreated Hodgkin's disease. In 12 of 15 cases, diminished absolute levels of T-lymphocytes in the peripheral blood were found; however, this was correlated with total lymphopenia. No direct relation...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:

    authors: Bukowski RM,Noguchi S,Hewlett JS,Deodhar S

    更新日期:1976-01-01 00:00:00

  • Comparative study of spleen pathology in drug abusers with thrombocytopenia related to human immunodeficiency virus infection and in patients with idiopathic thrombocytopenic purpura. A morphometric, immunohistochemical, and ultrastructural study.

    abstract::A morphometric and immunohistochemical study was performed to assess the spleen's alterations in patients with autoimmune thrombocytopenia and in drug abusers with thrombocytopenia (DAT) related to human immunodeficiency virus (HIV) infection. A total of 34 patients were included in the study: 20 DAT patients and 14 w...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/100.6.633

    authors: Marti M,Feliu E,Campo E,Palacin A,Berga L,Casals FJ,Urbano Ispizua A,Cardesa A,Rozman C

    更新日期:1993-12-01 00:00:00

  • Early monitoring of serum cardiac troponin I for assessment of coronary reperfusion following thrombolytic therapy.

    abstract::The authors report the use of cardiac troponin I (cTnI) for the early, noninvasive determination of coronary reperfusion following thrombolytic therapy. Cardiac troponin I, creatine kinase (CK)-MB, and myoglobin concentrations were measured in early serum specimens at 30, 60, and 90 minutes after initiation of therapy...

    journal_title:American journal of clinical pathology

    pub_type: 临床试验,杂志文章

    doi:10.1093/ajcp/105.1.6

    authors: Apple FS,Henry TD,Berger CR,Landt YA

    更新日期:1996-01-01 00:00:00

  • Establishing Evidence-Based Statistical Quality Control Practices.

    abstract:OBJECTIVES:To establish an objective, scientific, evidence-based process for planning statistical quality control (SQC) procedures based on quality required for a test, precision and bias observed for a measurement procedure, probabilities of error detection and false rejection for different control rules and numbers o...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/aqy158

    authors: Westgard JO,Westgard SA

    更新日期:2019-03-01 00:00:00