Misleading hemoglobin A1c levels in a patient with paroxysmal nocturnal hemoglobinuria.

abstract：OBJECTIVES:Bladder cancers invading the muscularis mucosae (MM) are treated differently from those invading the muscularis propria (MP). However, it may be difficult to determine the type of smooth muscle in transurethral resection (TUR) or biopsy specimens. We aimed to investigate the clinicopathologic features of bla...

journal_title：American journal of clinical pathology

authors： Hwang MJ,Kamat AM,Dinney CP,Czerniak B,Guo CC

更新日期：2020-07-07 00:00:00

abstract：:The authors tested a newly-developed computerized laser scanning cytometer (LSC) as a means of performing immunophenotypic analysis of hematologic specimens within their community hospital. Results were compared on a case-by-case basis with parallel flow cytometric and immunohistochemical data. A total of 71 specimens...

journal_title：American journal of clinical pathology

authors： Clatch RJ,Walloch JL,Zutter MM,Kamentsky LA

更新日期：1996-06-01 00:00:00

abstract：:The Department of Laboratory Medicine, University of Washington, has explored various management of organizational approaches over the past seven years. The Centralized Processing Area supported by a computerized information system has evolved from these efforts. Despite a decrease in U.W. hospital usage since 1968-69...

journal_title：American journal of clinical pathology

authors： Nussbaum B,Minckler T,Roby R,Ackerman E

更新日期：1977-02-01 00:00:00

abstract：:The cytologic features of fine-needle aspiration specimens from 16 breast carcinomas that closely simulated benign lesions were analyzed and compared to smears from fibroadenomas and fibrocystic change. No combination of features was found that accurately separated all benign and malignant cases. Many nuclei with disc...

journal_title：American journal of clinical pathology

authors： Rogers LA,Lee KR

更新日期：1992-08-01 00:00:00

abstract：:This article describes the seventh known case of blue nevus of the lymph node capsule and reviews the previously reported cases. The migration arrest hypothesis as an explanation for the occurrence of this lesion is favored rather than the "benign metastasis" hypothesis. The importance of the recognition of this pheno...

journal_title：American journal of clinical pathology

authors： Lamovec J

更新日期：1984-03-01 00:00:00

abstract：:The characteristics of the normal adult thymus in both sexes were determined in 50 cases of accidental death by a simplified quantitative histologic technic. A table of normal values derived from these findings was used for making comparisons with thymus from autopsies of 50 additional patients suffering terminal illn...

journal_title：American journal of clinical pathology

authors： Smith SM,Ossa-Gomez LJ

更新日期：1981-11-01 00:00:00

abstract：:Acute toxic hepatic necrosis is common and may be fatal. Predicting clinical outcome may be aided by following serum markers that could indicate recovery or may signify massive (substantial) destruction of functional liver mass. Previously, in a published case of chloroform poisoning, we serially assayed serum biomark...

journal_title：American journal of clinical pathology

authors： Horn KD,Wax P,Schneider SM,Martin TG,Nine JS,Moraca MA,Virji MA,Aronica PA,Rao KN

更新日期：1999-09-01 00:00:00

abstract：:The authors describe an unusual variant of alkaline phosphatase (ALP) discovered in a patient with a 90-fold increase in serum ALP. The variant ALP was indistinguishable from the bone isoenzyme when subjected to chemical inhibition, heat inactivation, lectin precipitation, and routine electrophoresis. However, treatme...

journal_title：American journal of clinical pathology

authors： Schreiber WE,Gorecki T,Bernstein V

更新日期：1991-05-01 00:00:00

abstract：:Human serum contains 2 isoforms of type-5 tartrate-resistant acid phosphatase (TRACP): 5a and 5b. TRACP-5b is osteoclastic. Our goal was to determine if serum TRACP-5a could originate from inflammatory macrophages (MPhi). We stained 246 paraffin-embedded tissue samples for TRACP using monoclonal antibody 9C5 (mab9C5) ...

journal_title：American journal of clinical pathology

authors： Janckila AJ,Slone SP,Lear SC,Martin A,Yam LT

更新日期：2007-04-01 00:00:00

abstract：:Current methods for testing stool samples for hemoglobin utilize peroxidase oxidation of chemical indicators such as guaiac or benzidine. These tests have frequent false-positive and false-negative results, complicating random screening for occult gastrointestinal bleeding. The authors have developed an immunochemical...

journal_title：American journal of clinical pathology

authors： Barrows GH,Burton RM,Jarrett DD,Russell GG,Alford MD,Songster CL

更新日期：1978-03-01 00:00:00

abstract：:Fine-needle cytology (FNC) of 292 palpable orbital and eyelid tumors was performed with a 25-gauge (0.5-mm), 3-cm needle and compared with the histopathologic findings in 286 cases. Among these 286 cases, a concordant diagnosis of malignancy and type was achieved in 249 cases (87%). False positive diagnoses were made ...

journal_title：American journal of clinical pathology

authors： Zajdela A,Vielh P,Schlienger P,Haye C

更新日期：1990-01-01 00:00:00

abstract：:The serum concentrations of alpha-fetoprotein of rats following experimental galactosamine-induced liver-cell necrosis accurately reflect the severity of preceding liver-cell damage as determined by elevation of serum transaminases. There is a very close correlation between the highest SGOT or SGPT serum activity foun...

journal_title：American journal of clinical pathology

authors： Sell S,Stillman D,Gochman N

更新日期：1976-11-01 00:00:00

abstract：OBJECTIVES:To demonstrate the impact of genetics specialists on identifying test order errors and improving reimbursement for genetic testing. METHODS:Forty-four cases in which whole exome sequencing (WES) was performed but not reimbursed were reviewed by a genetic counselor through simulated prospective and retrospec...

journal_title：American journal of clinical pathology

authors： Conway ME,Kalejta CD,Sternen DL,Singh IR

更新日期：2020-03-09 00:00:00

abstract：:"Chondroid chordoma" is a controversial and confusing entity that was originally described by Heffelfinger and colleagues as a biphasic malignant neoplasm possessing elements of both chordoma and cartilaginous tissue. Because the premise for this distinction was based strictly on histomorphologic criteria, the light m...

journal_title：American journal of clinical pathology

authors： Jeffrey PB,Biava CG,Davis RL

更新日期：1995-03-01 00:00:00

abstract：:Mantle cell lymphoma (MCL) and small lymphocytic lymphoma (SLL) exhibit similar but distinct immunophenotypic profiles. Many cases can be diagnosed readily by flow cytometry (FCM) alone; however, ambiguous cases are frequently encountered and necessitate additional studies, including immunohistochemical staining for c...

journal_title：American journal of clinical pathology

authors： Zare H,Bashashati A,Kridel R,Aghaeepour N,Haffari G,Connors JM,Gascoyne RD,Gupta A,Brinkman RR,Weng AP

更新日期：2012-01-01 00:00:00

abstract：:Five patterns of bone marrow infiltration by non-Hodgkin lymphoma or Hodgkin lymphoma are currently recognized, but a true follicular pattern of bone marrow involvement by follicular lymphoma has not been described. In 260 bone marrow trephine biopsy specimens involved by follicular lymphoma, we identified 12 cases wi...

journal_title：American journal of clinical pathology

authors： Torlakovic E,Torlakovic G,Brunning RD

更新日期：2002-11-01 00:00:00

abstract：Objectives:To determine non-American Society for Clinical Pathology pathology- and laboratory-related Choosing Wisely recommendations that drive effective test utilization in the laboratory. Methods:Data were collected via a two-part web-based survey distributed to a broad sample of pathologists and laboratory profess...

journal_title：American journal of clinical pathology

authors： Waibel E,Garcia E,Kelly M,Soles R,Hilborne L

更新日期：2018-02-17 00:00:00

abstract：:A 76-year-old white man previous diagnosed as having Waldenstrom's macroglobulinemia continued with persistent fevers and sweats for two and a half years. Recently, repeated automated differentials during 11 days of hospitalization failed to note any intracellular inclusions in the RBCs. Blood sent to the Microbiology...

journal_title：American journal of clinical pathology

authors： Bruckner DA,Garcia LS,Shimizu RY,Goldstein EJ,Murray PM,Lazar GS

更新日期：1985-04-01 00:00:00

abstract：:Reduction mammaplasty (RM) is a common surgical procedure that yields a variable amount of tissue for pathologic examination. Occult breast carcinomas are detected rarely in these specimens. We evaluated the pathologic findings in RM specimens performed in our institution during an 11.5-year period (July 1989 to Decem...

journal_title：American journal of clinical pathology

authors： Ishag MT,Bashinsky DY,Beliaeva IV,Niemann TH,Marsh WL Jr

更新日期：2003-09-01 00:00:00

abstract：:In order to determine the significance of 40% or more leukemic cells in hand-mirror configuration in the bone marrow (hand-mirror cell leukemia), eight of 34 cases of acute lymphoblastic leukemia and one of 17 cases of acute myeloblastic leukemia were collected from a six-year period. Five of the eight patients who ha...

journal_title：American journal of clinical pathology

authors： Glassy EF,Sun NC,Okun DB

更新日期：1980-11-01 00:00:00

abstract：:Free testosterone (FT) measurement by equilibrium dialysis and liquid chromatography-tandem mass spectroscopy (LCMS/MS) is the "gold standard." We hypothesized that calculated FT values could substitute for measured values; compared FT results reported by Walter Reed Army Medical Center (WRAMC), Washington, DC, with r...

journal_title：American journal of clinical pathology

authors： DeVan ML,Bankson DD,Abadie JM

更新日期：2008-03-01 00:00:00

abstract：:A method using the RNA polymerase chain reaction technique to diagnose infection retrospectively using single-stranded RNA enteroviruses in paraffin-embedded tissue blocks is reported. This method takes advantage of extreme sequence conservation in the 5' untranslated region of the enteroviral genome and uses two roun...

journal_title：American journal of clinical pathology

authors： Redline RW,Genest DR,Tycko B

更新日期：1991-11-01 00:00:00

abstract：:To investigate the issue of clonality in Richter's syndrome, phenotypic, molecular genetic, and cytogenetic studies were performed on tumor tissue from a patient with concurrent chronic lymphocytic leukemia and diffuse large cell lymphoma in a single lymph node specimen. The tumor was biphenotypic for immunoglobulin (...

journal_title：American journal of clinical pathology

authors： Nakamine H,Masih AS,Sanger WG,Wickert RS,Mitchell DW,Armitage JO,Weisenburger DD

更新日期：1992-05-01 00:00:00

abstract：:An antithrombin assay (AA) and an antithrombin assay modified by the addition of heparin (H-AA) were performed using sera from healthy subjects, patients predisposed to thrombosis, and patients with thromboembolic disease. Characteristic AA, and H-AA patterns were found in each group. Normal controls and four of 39 "p...

journal_title：American journal of clinical pathology

authors： Innerfield I,Stone ML,Mersheimer W,Clauss RD,Greenberg J

更新日期：1976-03-01 00:00:00

abstract：:Little is known concerning the pathology of spleens removed for traumatic injury. The authors studied the gross and microscopic features of 44 spleens removed for trauma and received at the Surgical Pathology Division of Parkland Memorial Hospital and 10 normal control spleens from the Medical Examiner's Office, Dalla...

journal_title：American journal of clinical pathology

authors： Farhi DC,Ashfaq R

更新日期：1996-04-01 00:00:00

abstract：:Using Venn diagrams derived from set theory, a mathematic model is presented that allows triple-label immunophenotypic analysis of cells based upon double-label measurements. Practical applications of this method are illustrated and discussed. Using this model, triple-label data concerning Leu-8 and Leu-9 (CD7) antige...

journal_title：American journal of clinical pathology

authors： Wood GS

更新日期：1989-07-01 00:00:00

abstract：:A two-sample plot is often used to display test results in clinical chemistry external quality control programs. The use of control materials at different concentrations calls for a re-evaluation of the two-sample plot. A modification of the two-sample plot is presented. The axes of the graph are graduated in units of...

journal_title：American journal of clinical pathology

authors： Elion-Gerritzen WE

更新日期：1977-01-01 00:00:00

abstract：:Bleeding problems are symptomatic of platelet delta-storage pool diseases (SPDs) such as Hermansky-Pudlak syndrome. Although at present no cure is available for delta-SPD, early diagnosis is of great importance for prophylactic and supportive treatment. This study tested the usefulness of a flow cytometric assay for p...

journal_title：American journal of clinical pathology

authors： Maurer-Spurej E,Pittendreigh C,Wu JK

更新日期：2007-04-01 00:00:00

abstract：:We describe 2 male patients in whom hepatosplenic gamma/delta T-cell lymphoma (HSTL) developed 6 and 10 years after renal transplantation. The onset was abrupt with systemic symptoms, cytopenia, and hepatosplenomegaly. The histologic examination of the spleen (case 1), liver, and bone marrow revealed sinusoidal infilt...

journal_title：American journal of clinical pathology

authors： Khan WA,Yu L,Eisenbrey AB,Crisan D,al Saadi A,Davis BH,Hankin RC,Mattson JC

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVES:The National Cancer Institute (NCI) National Clinical Trials Network performs phase II and III clinical trials, which increasingly rely on the submission of diagnostic formalin-fixed, paraffin-embedded tissue blocks for biomarker assessment. Simultaneously, advances in precision oncology require that clinica...

journal_title：American journal of clinical pathology

authors： Makhlouf H,Watson MA,Lankes HA,Weil C,Dickler M,Birrer M,Moskaluk C,Ramirez NC,Okby N,Alonsozana E,Barnes M,Goldman EB,Enos R,Lubensky I

更新日期：2020-01-02 00:00:00