Abstract：
:The characteristics of the normal adult thymus in both sexes were determined in 50 cases of accidental death by a simplified quantitative histologic technic. A table of normal values derived from these findings was used for making comparisons with thymus from autopsies of 50 additional patients suffering terminal illness. It was observed that thymic changes considered to be part of physiologic involution occurred earlier and were more advanced at a given age in males than in females. These changes included disappearance of septae, diminished demarcation between cortex and medulla, and a decreased number of Hassall's corpuscles with an increase in their size. Changes ascribed to disease included accelerated involution of the thymus accompanied by loss of septae, smaller lobules, increased adipose tissue and fusiform cells, a reduced number of lymphocytes and Hassall's corpuscles and a relative increase in the number of cystic corpuscles. No lymphoid follicles were observed. Changes were not identical in all disease conditions. In neoplasia, the limit between the cortex and medulla was preserved; in immune diseases, the epithelial nests of the medulla were increased.
journal_name
Am J Clin Patholjournal_title
American journal of clinical pathologyauthors
Smith SM,Ossa-Gomez LJdoi
10.1093/ajcp/76.5.657subject
Has Abstractpub_date
1981-11-01 00:00:00pages
657-65issue
5eissn
0002-9173issn
1943-7722journal_volume
76pub_type
杂志文章abstract：:Physicians are often forced to make decisions about the use of laboratory resources without adequate access to earlier results and related supporting information. Less than optimal use of the laboratory may result. The authors developed and deployed a clinical workstation meant to provide ready access to laboratory in...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
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journal_title：American journal of clinical pathology
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更新日期：1998-03-01 00:00:00
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pub_type： 杂志文章,评审
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journal_title：American journal of clinical pathology
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journal_title：American journal of clinical pathology
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journal_title：American journal of clinical pathology
pub_type： 杂志文章,评审
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更新日期：1996-07-01 00:00:00
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更新日期：1988-09-01 00:00:00
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journal_title：American journal of clinical pathology
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更新日期：1996-04-01 00:00:00
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更新日期：1998-07-01 00:00:00
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更新日期：1984-12-01 00:00:00
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journal_title：American journal of clinical pathology
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更新日期：2012-04-01 00:00:00
