ANA testing: a comparison of two kits and a discussion of specificity and sensitivity as criteria for selection of screening procedures.

abstract：Objectives:To analyze the economic impact of testing for activated protein C resistance (APC-R) due to factor V Leiden (FVL) mutation with APC-R with reflexive FVL genotyping (algorithmic approach) or genotyping alone. Methods:OptumLabs Data Warehouse (OLDW) data were used to assess testing approaches. Insurance claim...

journal_title：American journal of clinical pathology

authors： Perez Botero J,Majerus JA,Strege AK,Johnson RD,Chen D,Pruthi RK

更新日期：2017-06-01 00:00:00

abstract：:Little is known concerning the pathology of spleens removed for traumatic injury. The authors studied the gross and microscopic features of 44 spleens removed for trauma and received at the Surgical Pathology Division of Parkland Memorial Hospital and 10 normal control spleens from the Medical Examiner's Office, Dalla...

journal_title：American journal of clinical pathology

authors： Farhi DC,Ashfaq R

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVES:To assess the frequency of systemic mastocytosis (SM) in a large series of acute myeloid leukemia (AML) with t(8;21)(q22;q22). METHODS:We retrospectively characterized 40 bone marrow aspirate smears and biopsy specimens from patients with AML with t(8;21) for the presence of SM. Cases were assessed for mast...

journal_title：American journal of clinical pathology

authors： Johnson RC,Savage NM,Chiang T,Gotlib JR,Cherry AM,Arber DA,George TI

更新日期：2013-10-01 00:00:00

abstract：:Human papillomavirus (HPV) testing is more sensitive for the detection of cervical precancer and cancer than cervical cytology. The increased sensitivity of HPV testing and cytology combined ("cotesting") compared to cytology alone permitted professional societies to recommend 3-year screening intervals among the cote...

journal_title：American journal of clinical pathology

authors： Kinney W,Stoler MH,Castle PE

更新日期：2010-08-01 00:00:00

abstract：:Two unusual cases of acute lymphoblastic leukemia-hand mirror variant (ALL-HMV) are presented. One patient demonstrated a mixed immunophenotype with HLA-DR, My7, transferrin receptor surface markers, and terminal deoxynucleotidyl transferase positivity. To the authors' knowledge, this is the first ALL-HMV reported wit...

journal_title：American journal of clinical pathology

authors： Schumacher HR,Desai SN,McClain KL,Domenico DR,Dizikes GJ,Bird ML

更新日期：1989-04-01 00:00:00

abstract：:Postmortem pathologic and bacteriologic reports were analyzed for 237 deaths occurring at a large institution for the mentally retarded from 1958 to 1973. Bronchopneumonia, aspiration pneumonia, and lipid pneumonia were frequently reported at autopsy, and in a total of 146 cases (61.6%) at least one type of pneumonia ...

journal_title：American journal of clinical pathology

authors： Polednak AP

更新日期：1977-02-01 00:00:00

abstract：:Recombinant factor VIIa (rFVIIa) has become available for treating people with hemophilia with inhibitors who experience bleeding or require surgery. It has become apparent that rFVIIa is useful in controlling bleeding in a variety of clinical situations. This review attempts to collate and summarize the nonhemophilia...

journal_title：American journal of clinical pathology

authors： Midathada MV,Mehta P,Waner M,Fink LM

更新日期：2004-01-01 00:00:00

abstract：:Diarrheal diseases caused by bacterial pathogens are important causes of morbidity in the United States, and considerable laboratory resources are spent to detect these enteric pathogens. This article reviews recent developments in the detection and identification of Campylobacter spp, enterohemorrhagic Escherichia co...

journal_title：American journal of clinical pathology

authors： Nolte FS

更新日期：1994-04-01 00:00:00

abstract：:Cellular and humoral immunity combine to determine the outcome following exposure to hepatitis virus and are implicated in the proposed pathogenetic mechanism for acute and chronic hepatitis. Although antibody to HBsAg is found in virtually all following recovery from hepatitis B, a cell-mediated response to HBsAg can...

journal_title：American journal of clinical pathology

authors： Lee WM

更新日期：1976-05-01 00:00:00

abstract：:A primary hepatic tumor with histologic features suggestive of carcinoid tumor is reported, and six previously reported cases reviewed. Tumor cells contained electron dense secretory granules with an average diameter 150-200 nm which demonstrated positive argyrophilic reactions. On immunohistochemistry, chromogranin A...

journal_title：American journal of clinical pathology

authors： Miura K,Shirasawa H

更新日期：1988-04-01 00:00:00

abstract：:The occurrence of antibodies belonging to IgG class of immunoglobulins with specificity for short ragweed and Bermuda grass in the sera of nonatopic subjects and patients with inhalant allergy (at the time of initial diagnosis, following specific immunotherapy was investigated with an enzyme immunoassay. The intra-ass...

journal_title：American journal of clinical pathology

authors： Ali M,Ramanarayanan MP,Nalebuff DJ,Fadal RG,Willoughby JW

更新日期：1983-09-01 00:00:00

abstract：:Plasma biomarker analysis requires intact unbiased starting material. We analyzed the effects on plasma protein profiles of protease inhibitor cocktails and preprocessing storage. Plasma from 12 healthy subjects collected with and without protease inhibitors was prepared immediately and after 2 hours of room temperatu...

journal_title：American journal of clinical pathology

authors： Ayache S,Panelli M,Marincola FM,Stroncek DF

更新日期：2006-08-01 00:00:00

abstract：:Thrombocytosis may reflect a primary myeloproliferative disorder or be a secondary reaction to other pathologic processes. Patients with persistent unexplained thrombocytosis meeting criteria of primary thrombocythemia had elevated levels of serum lactic dehydrogenase, whereas comparable patients with secondary thromb...

journal_title：American journal of clinical pathology

authors： Budman DR,Lackner H,Berczeller P,Silber R

更新日期：1981-06-01 00:00:00

abstract：:A structure resembling a sulfur granule found in histologic sections of endometrium from patients with intrauterine contraceptive devices is described. It is distinguished from a true sulfur granule on morphologic grounds and is further characterized as a foreign substance, most probably fragments of the synthetic con...

journal_title：American journal of clinical pathology

authors： O'Brien PK,Roth-Moyo LA,Davis BA

更新日期：1981-06-01 00:00:00

abstract：:Members of the genus Pseudomonas are widely implicated in human disease. Although most isolates are P. aeruginosa, there have been serious outbreaks of infection with other members of the genus. The susceptibility patterns of 5) Pseudomonas isolates are reported. It was notable that of the four antibiotics tested, uni...

journal_title：American journal of clinical pathology

authors： Tilton RC,Steingrimsson O,Ryan RW

更新日期：1978-04-01 00:00:00

abstract：:Little information has been reported describing antigen stability in plasma cell myeloma. In this study, the expression frequency and stability of 2 potential therapeutic targets, CD20 and CD52, along with the frequently aberrantly expressed CD56 antigen, were evaluated by flow cytometric analyses in 56 patients with ...

journal_title：American journal of clinical pathology

authors： Cao W,Goolsby CL,Nelson BP,Singhal S,Mehta J,Peterson LC

更新日期：2008-06-01 00:00:00

abstract：:A case of adenocarcinoma of the small bowel arising in pre-existing transmural ileitis (Crohn's disease) is reported and 28 previously reported cases are reviewed. Carcinoma associated with transmural enteritis occurs more often in the distal ileum, in younger patients, and in more males than expected from published d...

journal_title：American journal of clinical pathology

authors： Savage RA,Farmer RG,Hawk WA

更新日期：1975-02-01 00:00:00

abstract：:Reducing the rate of avoidable errors is crucial to patient safety. Telephone calls with misunderstood critical results constitute one area in which opportunities for improvement exist. The aviation industry has dealt with this issue by requiring pilots to repeat instructions received from the air traffic controller. ...

journal_title：American journal of clinical pathology

authors： Barenfanger J,Sautter RL,Lang DL,Collins SM,Hacek DM,Peterson LR

更新日期：2004-06-01 00:00:00

abstract：:Most cutaneous T-cell lymphomas are derived from mature postthymic T cells of the CD4 subtype. When other less common profiles are encountered, a diagnostic challenge is posed. Accurate categorization is critical because of the specificity of therapeutic regimens, including biologics. A 65-year-old woman was seen in 2...

journal_title：American journal of clinical pathology

authors： Magro CM,Seilstad KH,Porcu P,Morrison CD

更新日期：2006-07-01 00:00:00

abstract：:Myxomatous degeneration of the mitral valve is a disease of unknown etiology that is associated with many ominous complications. A case in which non-bacterial thrombotic endocarditis, superimposed on a myxomatous mitral valve, resulted in systemic embolization to the brain, heart, and kidney is presented. The purpose ...

journal_title：American journal of clinical pathology

authors： Geyer SJ,Franzini DA

更新日期：1979-09-01 00:00:00

abstract：:Reported is a case of a rare lymphoepithelial cyst of the tail of the pancreas that developed in a young man with no symptoms. To the authors' knowledge, it is the first case described to be entirely situated within the pancreas, thus confirming its pancreatic origin. Biologic behavior appears to be entirely benign, a...

journal_title：American journal of clinical pathology

authors： DiCorato MP,Schned AR

更新日期：1992-08-01 00:00:00

abstract：:Basaloid squamous cell carcinoma (BSCC) and carcinosarcoma of the esophagus are rare entities, making up fewer than 2% of esophageal malignancies. Comparative genomic hybridization (CGH) in 1 case of BSCC and 2 cases of carcinosarcoma and subsequent array CGH in 1 case each of BSCC and carcinosarcoma revealed common c...

journal_title：American journal of clinical pathology

authors： Schaefer IM,Enders C,Polten A,Haller F,Frölich AM,Cameron S,Schüler P,Schweiger P,Gunawan B,Beham A,Füzesi L

更新日期：2011-04-01 00:00:00

abstract：:The present study evaluated the origin of endothelial and epithelial cells, as well as of lymphocytes and macrophages, after lung transplantation. Biopsy specimens from patients who underwent lung and heart-lung transplantation and received organs of sex-mismatched donors were studied by means of nonisotopic in situ h...

journal_title：American journal of clinical pathology

authors： Bittmann I,Dose T,Baretton GB,Müller C,Schwaiblmair M,Kur F,Löhrs U

更新日期：2001-04-01 00:00:00

abstract：:The authors report a case of metastatic prostate cancer masquerading as a primary lung tumor. Histologically, the lung tumor displayed eosinophilic crystalloids in the malignant glands typical of those previously described in prostatic adenocarcinoma. Review of histologic material from 30 additional patients with meta...

journal_title：American journal of clinical pathology

authors： Molberg KH,Mikhail A,Vuitch F

更新日期：1994-03-01 00:00:00

abstract：:Breast cancer is the result of a multistage carcinogenic process. Initiation, promotion, dependency and autonomy make up a sequence of experimentally distinguishable phases of this process. Progression--the transition from dependency on hormonal support to autonomy--is demonstrable clinically. High-affinity saturatabl...

journal_title：American journal of clinical pathology

authors： Brennan MJ

更新日期：1975-12-01 00:00:00

abstract：:A multiplex polymerase chain reaction (PCR) assay using oligonucleotide primers to detect mecA and 16S ribosomal RNA gene was developed to aid in identification of methicillin-resistant staphylococci. Validation included 99 isolates of staphylococcus grouped into one of five categories: methicillin-susceptible coagula...

journal_title：American journal of clinical pathology

authors： Salisbury SM,Sabatini LM,Spiegel CA

更新日期：1997-03-01 00:00:00

abstract：:Although the relationship between pathologic features and clinical outcome is well established in adult adrenocortical neoplasms, the prognostic value of these features in pediatric adrenocortical neoplasms (PACN) is unclear. In a series of PACNs from 54 Brazilian children, the authors retrospectively investigated the...

journal_title：American journal of clinical pathology

authors： Bugg MF,Ribeiro RC,Roberson PK,Lloyd RV,Sandrini R,Silva JB,Epelman S,Shapiro DN,Parham DM

更新日期：1994-05-01 00:00:00

abstract：:Two hundred serum samples were tested with two assays for rapid detection of cytomegalovirus (CMV) antibodies. The assays were CMV Scan, a two-step latex particle agglutination assay for CMV IgG and IgM antibodies, and TranSTAT-CMV, a newly available six-step solid-phase enzyme immunoassay for CMV IgG antibodies. Comp...

journal_title：American journal of clinical pathology

authors： Roseff SD,Campos JM

更新日期：1993-05-01 00:00:00

abstract：:"Chondroid chordoma" is a controversial and confusing entity that was originally described by Heffelfinger and colleagues as a biphasic malignant neoplasm possessing elements of both chordoma and cartilaginous tissue. Because the premise for this distinction was based strictly on histomorphologic criteria, the light m...

journal_title：American journal of clinical pathology

authors： Jeffrey PB,Biava CG,Davis RL

更新日期：1995-03-01 00:00:00

abstract：:Transfusion-related acute lung injury (TRALI) is the leading cause of mortality from transfusion therapy. Recipient, donor, and blood product risk factors may have important roles in the occurrence of TRALI. A case-control pilot study of 6 TRALI cases in which HLA-antibody concordance was found and 20 control subjects...

journal_title：American journal of clinical pathology

authors： Sanchez R,Bacchetti P,Toy P

更新日期：2007-07-01 00:00:00