Abstract:
:Postmortem pathologic and bacteriologic reports were analyzed for 237 deaths occurring at a large institution for the mentally retarded from 1958 to 1973. Bronchopneumonia, aspiration pneumonia, and lipid pneumonia were frequently reported at autopsy, and in a total of 146 cases (61.6%) at least one type of pneumonia was reported. Postmortem bacteriologic cultures in a smaller group revealed high recovery rates of staphylococci (coagulase-positive), hemolytic streptococci, and gram-negative bacilli in throat and lung cultures. Enteric aerobic gram-negative bacilli were particularly frequent along with yeast (Candida albicans). The institutionalized retarded appear similar to other hospitalized populations, in that a large proportion of hospital-acquired respiratory infections is related to aerobic gram-negative bacilli. The high frequency of aspiration and its sequelae in this population is unusual, however, and post-mortem bacteriologic findings appear consistent with those of antemortem studies of cases of aspiration pneumonia.
journal_name
Am J Clin Patholjournal_title
American journal of clinical pathologyauthors
Polednak APdoi
10.1093/ajcp/67.2.190subject
Has Abstractpub_date
1977-02-01 00:00:00pages
190-5issue
2eissn
0002-9173issn
1943-7722journal_volume
67pub_type
杂志文章abstract::Histologic diagnosis of a nonpalpable breast lesion requires the following: (1) mammographically directed excision of the suspect lesion, (2) recovery of the target lesion from the tissue specimen, and (3) demonstration of the lesion in histologic section. Recovery of lesional tissue is a function of localization with...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/92.4.452
更新日期:1989-10-01 00:00:00
abstract::Anti-sperm antibodies from serum and seminal plasma were detected by concurrent flow cytometry and epifluorescence microscopy using fluorescein-conjugated antihuman immunoglobulins. Experimental conditions were designed, taking advantage of several monoclonal antisperm antibodies, to test aspects of the assay before c...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/95.2.242
更新日期:1991-02-01 00:00:00
abstract::An anti-serum against human neuron-specific enolase (NSE), raised in sheep, has been characterized and used for immunocytochemical localization of NSE in paraffin sections of normal tissues and lung cancers. Of the small cell carcinomas (SCC), 69 out of 99 (70%) cases stained with the anti-serum. Maltreated biopsies s...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/84.1.1
更新日期:1985-07-01 00:00:00
abstract::Characteristically, mantle cell lymphoma (MCL) expresses surface immunoglobulin (sIg), CD19, CD20, and CD5 and lacks CD10 and CD23. Rare CD5-MCL variants have been described. This report describes a case of leukemic MCL with morphologically and immunophenotypically distinct classic MCL and blastoid-variant MCL (BV-MCL...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/UD2C-6JVP-WHXQ-Q217
更新日期:2004-07-01 00:00:00
abstract::The clinical, light microscopic, and immunohistochemical features of 14 sinonasal malignant melanomas were studied to show their diverse morphologic appearance and distinction from therapeutically more amenable neoplasms that occur in this region. The tumors arose in 6 men and 8 women (median age, 70 years). Eleven pa...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/96.6.689
更新日期:1991-12-01 00:00:00
abstract::Human serum contains 2 isoforms of type-5 tartrate-resistant acid phosphatase (TRACP): 5a and 5b. TRACP-5b is osteoclastic. Our goal was to determine if serum TRACP-5a could originate from inflammatory macrophages (MPhi). We stained 246 paraffin-embedded tissue samples for TRACP using monoclonal antibody 9C5 (mab9C5) ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/DGEA9BE2VE5VCFYH
更新日期:2007-04-01 00:00:00
abstract::Pseudomonas alcaligenes is a common soil and water inhabitant that has rarely been proven a human pathogen. We describe a fatal case of Pseudomonas alcaligenes endocarditis. The need for accurate identification of unusual organisms isolated in a clinical setting are discussed. ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/79.2.245
更新日期:1983-02-01 00:00:00
abstract::Factor V Leiden (FVR506Q) is a genetic defect in the factor V (FV) molecule that confers resistance to proteolysis by activated protein C (APC) and is the most common abnormality detected in patients studied for hereditary thrombophilia. The initial screening test for this abnormality was a comparison of the activated...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/109.4.387
更新日期:1998-04-01 00:00:00
abstract::Although Stat tests are one of the most important features of clinical laboratory performance, the indexed literature is devoid of significant discussion of the subject. The authors, undertook a study by querying hospital laboratories about their current practices and received 38 useable answers dealing with the types...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/69.5.520
更新日期:1978-05-01 00:00:00
abstract::This study compared the ability to diagnose and accurately classify hepatic mass lesions by ultrasound-guided biopsy using two different needle types: a 20 gauge needle that yielded primarily cytologic material and an 18 gauge automated core biopsy needle. Slides prepared from each of the needle types were separately ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/104.5.583
更新日期:1995-11-01 00:00:00
abstract::The ideal method of heparinization should achieve therapeutic concentrations (0.2-0.5 IU/mL) in the artificial kidney and the least possible amount of heparin in the patient. Total heparinization using a bolus dose (8400 IU) followed by continuous infusion of heparin (20 IU/min), initially showed 1.4-2.4 IU/mL in the ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/84.3.317
更新日期:1985-09-01 00:00:00
abstract::The present study evaluated the origin of endothelial and epithelial cells, as well as of lymphocytes and macrophages, after lung transplantation. Biopsy specimens from patients who underwent lung and heart-lung transplantation and received organs of sex-mismatched donors were studied by means of nonisotopic in situ h...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/GAFN-5MPA-LY8E-DTPQ
更新日期:2001-04-01 00:00:00
abstract::In the absence of clinical signs, elevated values of the cardiac isoforms of troponin T (cTnT) and I (cTnI) can be found in the serum samples of some patients with skeletal muscle myopathies; the cause is unclear. We studied the messenger RNA (mRNA) expression of cTnT and cTnI in the skeletal muscles of 24 patients wi...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:
更新日期:2000-10-01 00:00:00
abstract::The authors have developed an immunoalkaline phosphatase method and have applied it with success to the study of blood cells. They have now observed that macrophages in tissues and in serous effusions may be nonspecifically stained when immunoalkaline phosphatase methods are used. A systematic study of this endogenous...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/84.4.476
更新日期:1985-10-01 00:00:00
abstract::The Sysmex R-3000 (TOA Medical Electronics, Kobe, Japan) evaluates maturation of reticulocytes by quantitating the fraction of reticulocytes within low-, middle-, and high-fluorescence intensity regions. We defined the immature reticulocyte fraction (IRF) as the sum of the fraction of high-fluorescence intensity regio...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVES:This session of the 2013 Society of Hematopathology/European Association for Haematopathology Workshop was dedicated to B-acute lymphoblastic leukemia (B-ALL)/lymphoblastic lymphoma (LBL) with recurrent translocations and not otherwise specified. METHODS:In this review, we summarize the cases discussed duri...
journal_title:American journal of clinical pathology
pub_type: 杂志文章,评审
doi:10.1309/AJCPAN7BH5DNYWZB
更新日期:2015-09-01 00:00:00
abstract::This article explores 3 aspects of breast diagnosis that are currently under investigation and about which our thinking has recently undergone considerable reshaping. The trend toward more frequent evaluation of clinically subtle lesions has suggested that it might be necessary to understand thefine-needle aspiration ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章,评审
doi:10.1309/29FP-0QAU-CMJY-BK3U
更新日期:2000-05-01 00:00:00
abstract::Screening for serum lipid disorders is recommended by numerous specialty societies to identify patients at risk for coronary heart disease (CHD). The best screening tests will identify patients at highest risk for CHD who would benefit from intervention. This report discusses an appropriate test panel to use as the in...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/103.4.380
更新日期:1995-04-01 00:00:00
abstract::Under carefully controlled conditions in a clinical research ward, conjugated primary bile-acid concentrations were measured by a 125I-radioimmunoassay every eight hours for four days in seven healthy control subjects and ten patients with hepatic disease (five with cirrhosis, three with primary biliary cirrhosis and ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/73.2.196
更新日期:1980-02-01 00:00:00
abstract::Cell counter-based formulas have been used in the differential diagnosis of microcytic anemia. The measurement of RBC subpopulations is now available on the Sysmex XE 5000 analyzer (Sysmex, Kobe, Japan). We describe the new formulas: % microcytic - % hypochromic; and % microcytic - % hypochromic - red cell distributio...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/AJCPJRH1I0XTNFGA
更新日期:2011-03-01 00:00:00
abstract::Lymphocyte populations with abnormal kappa/lambda ratios have been described previously in B-cell non-Hodgkin's lymphomas and in lymphoid hyperplasia. The authors studied 12 patients in whom lymph nodes diagnostic of Hodgkin's disease contained evidence of monoclonal lymphocyte proliferation. One patient subsequently ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/82.6.674
更新日期:1984-12-01 00:00:00
abstract::With various methods, BRAF mutations have been detected in 73.4% to 87.1% of papillary thyroid carcinomas (PTCs) in Korea. We assessed the ability of allele-specific polymerase chain reaction using a dual priming oligonucleotide system, compared with direct sequencing and pyrosequencing, to detect BRAF mutations in fi...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/AJCPO3F2ENKMDTUS
更新日期:2010-05-01 00:00:00
abstract::The thickness of eosinophilic band in collagenous colitis (CC) was assessed by 3 methods: histologic estimates (22 observers), conventional measurements using a calibrated micrometric scale (1 observer), and semiautomatic micrometric measurements (1 observer). By the histologic estimate technique, 7.4% of the results ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/K7MH8UCK3MR7Q77L
更新日期:2008-09-01 00:00:00
abstract::The radioimmunoassay of ACTH was used in a routine laboratory to localize the site of the lesion in 20 patients with Cushing's syndrome. Eight of the patients had no detectable circulating ACTH and had adrenal tumors removed, 12 had high levels and were diagnosed as having pituitary Cushing's syndrome. Very high level...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/64.5.618
更新日期:1975-11-01 00:00:00
abstract::We compared immunohistochemical expression of hepatocyte growth factor (HGF), c-met, alpha-inhibin, estrogen receptor (ER), and progesterone receptor (PR) in 10 pancreatic mucinous cystic neoplasms (PMCNs), 8 hepatobiliary cystadenomas (HBCs), and 6 simple liver cysts (SLCs).All HBCs and PMCNs were in women (mean ages...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/U2BBP4EMBAHCM6E6
更新日期:2008-02-01 00:00:00
abstract::The international sensitivity index (ISI) calibration of point-of-care-test (POCT) prothrombin time (PT) whole blood monitors is complex, requiring manual PT testing of 60 patients' and 20 healthy subjects' plasma samples. The possibility of reducing these numbers was studied by a Monte Carlo Bootstrap study for 2 POC...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/M1FE-DDVX-2V81-K5MP
更新日期:2002-06-01 00:00:00
abstract::The diagnostic value of glypican 3 (GPC3) immunostaining on needle biopsy specimens has not been well assessed. In this study, 120 liver needle biopsy specimens, including 46 from cirrhotic livers and 74 hepatocellular carcinomas (HCCs), were immunohistochemically examined for expression of GPC3. The results showed st...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/WMB5PX57Y4P8QCTY
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVES:An intraoperative consultation (IOC) checklist was developed and implemented aimed at standardizing slide labeling and monitoring metrics central to quality and safety in surgical pathology. DESIGN:Data were collected for all IOC cases over a 9-month period. Slide labeling defect rates and IOC turnaround ti...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/aqz009
更新日期:2019-05-03 00:00:00
abstract::Thirty drugs used primarily in critical care and hospital settings were tested in vitro to observe interference on glucose measurements with 6 hand-held glucose meters and a portable glucose analyzer. Paired differences of glucose measurements between drug-spiked samples and unspiked control samples were calculated to...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/QAW1-X5XW-BVRQ-5LKQ
更新日期:2000-01-01 00:00:00
abstract::In today's environment, many laboratories and pathology practices are challenged to maintain or increase their quality while simultaneously lowering their overall costs. The cost of improving specimen processes is related to quality, and we demonstrate that actual costs can be reduced by designing "quality at the sour...
journal_title:American journal of clinical pathology
pub_type: 杂志文章,评审
doi:10.1309/AJCPSMQYAF6X1HUT
更新日期:2012-09-01 00:00:00