Detection of BRAF mutations in thyroid nodules by allele-specific PCR using a dual priming oligonucleotide system.

abstract：:Primary angiosarcomas of the uterus are exceedingly rare. The authors report a unique case of this entity arising in connection with uterine leiomyomas. The malignant tumor cells showed focally epithelioid features and were immunoreactive for keratin. Electron microscopy and immunohistochemistry confirmed their endoth...

journal_title：American journal of clinical pathology

authors： Tallini G,Price FV,Carcangiu ML

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVES:To describe four cases of an uncommon type of acalculous cholecystitis/cholangitis characterized by increased intraepithelial lymphocytes within the biliary epithelium. METHODS:Cases were prospectively compiled during regular surgical pathology sign-out. Clinical information was obtained from the electronic...

journal_title：American journal of clinical pathology

authors： Jessurun J

更新日期：2015-01-01 00:00:00

abstract：:Breast cancer in men is a rare condition affecting only 1,000 men each year in the United States. Hormonal, genetic, and perhaps environmental factors appear to be important in development of the disease. Clinically, breast cancer in men resembles that seen in woman. Histologically the diseases are indistinguishable, ...

journal_title：American journal of clinical pathology

authors： Hecht JR,Winchester DJ

更新日期：1994-10-01 00:00:00

abstract：Objectives:To analyze interobserver reproducibility and compare practice patterns between academic and community settings of Lower Anogenital Squamous Terminology (LAST). Methods:In total, 132 anal biopsy slides were revised as well as p16 immunostains. Results:LAST was used in 49% of cases (academic center, 68%; sat...

journal_title：American journal of clinical pathology

authors： Roma AA,Liu X,Patil DT,Xie H,Allende D

更新日期：2017-07-01 00:00:00

abstract：:Demonstration of prostate-specific acid phosphatase by immunologic methods in tissue sections or in plasma necessitates a monospecific antiserum. This is produced by immunizing rabbits with pure prostate-specific acid phosphatase antigen, prepared from seminal fluid. The ejaculate is centrifuged, dialyzed against a ci...

journal_title：American journal of clinical pathology

authors： de Vries GP,Slob AW,Jöbsis AC,Meijer AE,Sanders GT

更新日期：1979-12-01 00:00:00

abstract：:Serrated adenomas are the precursors of at least 5.8% of colorectal cancers; otherwise little is known of their clinical significance in comparison with conventional adenomas and hyperplastic polyps. We compared the risk of metachronous lesions in colorectal serrated adenomas, conventional adenomas, and hyperplastic p...

journal_title：American journal of clinical pathology

authors： Lazarus R,Junttila OE,Karttunen TJ,Mäkinen MJ

更新日期：2005-03-01 00:00:00

abstract：:An automated fluorescent immunoassay system (FIAX) was compared with complement fixation (CF) for measuring antibodies to cytomegalovirus (CMV) and herpes simplex virus (HSV) in clinical specimens. Compared with CF the specificity of FIAX (ability to detect a negative titer) was 95% for CMV and 92% for HSV. The sensit...

journal_title：American journal of clinical pathology

authors： Friedman HM,Tustin NB,Hitchings MM,Plotkin SA

更新日期：1981-09-01 00:00:00

abstract：:We compared 1-stage clot-based, chromogenic, and immunoassay methods for measuring factor VIII in plasma with a focus on the measurement of elevated levels of factor VIII. The chromogenic assay showed the best interassay imprecision for factor VIII levels near 150 IU/dL. The best correlation was between the 1-stage cl...

journal_title：American journal of clinical pathology

authors： Chandler WL,Ferrell C,Lee J,Tun T,Kha H

更新日期：2003-07-01 00:00:00

abstract：:A flow cytometric technic was developed to detect platelet surface-bound immunoglobulin in patients with thrombocytopenia. Elevated platelet surface IgG and/or IgM was detected in 90.9% of patients with immune thrombocytopenia purpura (ITP). False positive results occurred in 9.3% of patients with nonimmune thrombocyt...

journal_title：American journal of clinical pathology

authors： Rosenfeld CS,Nichols G,Bodensteiner DC

更新日期：1987-04-01 00:00:00

abstract：:A 63-year-old previously healthy woman presented with acute meningitis. Cultures of the cerebrospinal fluid yielded a serotype 1/2a isolate of Listeria monocytogenes that was biochemically typical in all respects, other than the reproducible lack of catalase production. During therapy, the patient developed oculomotor...

journal_title：American journal of clinical pathology

authors： Swartz MA,Welch DF,Narayanan RP,Greenfield RA

更新日期：1991-07-01 00:00:00

abstract：:In a child with renal failure and oliguria due to hyperoxaluria myelophthisis developed as a result of extensive bone-marrow replacement with calcium oxalate crystals and an accompanying fibrous proliferations. The histopathology associated with this metabolic disorder was demonstrated in posterior iliac crest bone-ma...

journal_title：American journal of clinical pathology

authors： McKenna RW,Dehner LP

更新日期：1976-12-01 00:00:00

abstract：:In lung transplant recipients, bronchoalveolar lavage (BAL) is mainly performed to detect infectious agents. However, in addition to microorganisms, epithelial cell atypia may be identified, and determination of its significance is necessary. Specimens obtained at BAL in lung and heart-lung transplant recipients (LTRs...

journal_title：American journal of clinical pathology

authors： Ohori NP

更新日期：1999-08-01 00:00:00

abstract：:We further characterize the heterogeneous carcinomas of the papilla of Vater (CPVs) in relation to various clinicopathologic patient characteristics and patient survival. Of the 71 reevaluated CPVs, 32 were intestinal, 26 were pancreatobiliary, 6 were mixed, 4 were mucinous, and 3 were poorly differentiated carcinomas...

journal_title：American journal of clinical pathology

authors： Kohler I,Jacob D,Budzies J,Lehmann A,Weichert W,Schulz S,Neuhaus P,Röcken C

更新日期：2011-02-01 00:00:00

abstract：:Patients using anticoagulation point-of-care (POC) monitors are advised to periodically test these systems against laboratory methods to monitor performance. The international normalized ratio (INR), however, can vary between test systems owing to different instrument-reagent combinations. In a randomized study evalua...

journal_title：American journal of clinical pathology

authors： Sunderji R,Gin K,Shalansky K,Carter C,Chambers K,Davies C,Schwartz L,Fung A

更新日期：2005-02-01 00:00:00

abstract：:Whipple disease is a rare, chronic multisystem disease associated with the recently characterized organism Tropheryma whippelii. Extraintestinal manifestation involving the central nervous system, heart, and joints occasionally occurs. Involvement of the abdominal lymph nodes, especially the mesenteric and periaortic ...

journal_title：American journal of clinical pathology

authors： Alkan S,Beals TF,Schnitzer B

更新日期：2001-12-01 00:00:00

abstract：:For quality-control purposes, federal regulations require cytology laboratories to compare Papanicolaou smear and cervical biopsy reports, if available, and determine the cause of any discrepancies. The authors reviewed 56,497 cervicovaginal smears, of which 1,582 (2.8%) had a subsequent cervical biopsy or endocervica...

journal_title：American journal of clinical pathology

authors： Joste NE,Crum CP,Cibas ES

更新日期：1995-01-01 00:00:00

abstract：:We sought to determine the sensitivity and specificity of immunohistochemistry using the TORDJI-22 MoAb (BioGenex, San Ramon, Calif), which is specific for the C-100 protein of the hepatitis C virus, compared with reverse transcriptase-polymerase chain reaction (RT-PCR) of tissue for viral RNA. RT-PCR had been perform...

journal_title：American journal of clinical pathology

authors： Brody RI,Eng S,Melamed J,Mizrachi H,Schneider RJ,Tobias H,Teperman LW,Theise ND

更新日期：1998-07-01 00:00:00

abstract：:A case of congenital Pelger-Hüet anomaly of the peripheral blood cells is described. Electronmicroscopic examination of the blood cells revealed nuclear bridges and appendices in the polymorphonuclear leukocytes. The number of cytoplasmic granules was diminished, but the size of the secondary granules was markedly inc...

journal_title：American journal of clinical pathology

authors： Djaldetti M,Weiss S,Gafter U

更新日期：1976-06-01 00:00:00

abstract：:Two hundred serum samples were tested with two assays for rapid detection of cytomegalovirus (CMV) antibodies. The assays were CMV Scan, a two-step latex particle agglutination assay for CMV IgG and IgM antibodies, and TranSTAT-CMV, a newly available six-step solid-phase enzyme immunoassay for CMV IgG antibodies. Comp...

journal_title：American journal of clinical pathology

authors： Roseff SD,Campos JM

更新日期：1993-05-01 00:00:00

abstract：:There is a need for a simple, sensitive, specific, and inexpensive test for immunoglobulin M antibody to hepatitis B core antigen (anti-HBc IgM). A solid phase passive hemagglutination test (SP-PHA) was developed for this purpose and compared with the enzyme-linked immunosorbent assay (ELISA) test. Hepatitis B core an...

journal_title：American journal of clinical pathology

authors： Petchclai B,Khupulsup K,Kurathong S

更新日期：1987-02-01 00:00:00

abstract：:Thirteen cases of disseminated Mycobacterium avium-intracellulare (MAI), representing a total of 27 bone marrow specimens, were studied. The patients ranged from 25 to 46 years of age and included ten immunocompromised and three immunocompetent hosts. Peripheral blood findings included anemia in all patients, leukopen...

journal_title：American journal of clinical pathology

authors： Farhi DC,Mason UG 3rd,Horsburgh CR Jr

更新日期：1985-04-01 00:00:00

abstract：:HMB45 is a melanoma-specific monoclonal antibody that has found widespread use in diagnostic pathology. Recent reports, however, have suggested that this antibody may cross-react with a small number of carcinomas and other epithelial cells. The authors tested the hypothesis that these latter reports represent examples...

journal_title：American journal of clinical pathology

authors： Bonetti F,Pea M,Martignoni G,Mombello A,Colombari R,Zamboni G,Scarpa A,Piubello Q,Bacchi CE,Gown AM

更新日期：1991-04-01 00:00:00

abstract：:The cases of five patients who had sinus histiocytosis with massive lymphadenopathy accompanied by osseous involvement by the disease are presented. Four of the five patients were children. The bone lesions were multiple in four cases and solitary in one. The long bones were most commonly involved (three patients); ot...

journal_title：American journal of clinical pathology

authors： Walker PD,Rosai J,Dorfman RF

更新日期：1981-02-01 00:00:00

abstract：OBJECTIVES:Peritoneal mesothelial cysts have been reported under various terms, including benign cystic mesothelioma, usually in the form of case reports/series, whereas extraperitoneal cases are rarely reported. Our objective was to report the detailed characteristics of cystic lesions of the serosal cavities. METHOD...

journal_title：American journal of clinical pathology

authors： Karpathiou G,Casteillo F,Dridi M,Peoc'h M

更新日期：2020-12-01 00:00:00

abstract：:To study the histogenesis of and determine the most useful markers for diagnosing anaplastic thyroid carcinoma (ATC), 32 cases, including 2 with numerous osteoclast-like cells, were stained with a battery of antibodies to epithelial (keratin, epithelial membrane antigen [EMA], carcinoembryonic antigen [CEA]), mesenchy...

journal_title：American journal of clinical pathology

authors： Ordóñez NG,El-Naggar AK,Hickey RC,Samaan NA

更新日期：1991-07-01 00:00:00

abstract：:We assessed cytologic specimens from 11 mantle cell lymphomas (MCLs) and 32 other B-cell non-Hodgkin lymphomas (NHLs) for 11q13 breakpoints using a 2-color fluorescence in situ hybridization (FISH) assay that uses an 11q13 probe centered on the CCND1 gene and a centromeric chromosome 11 probe (CEP11). The number of nu...

journal_title：American journal of clinical pathology

authors： Katz RL,Caraway NP,Gu J,Jiang F,Pasco-Miller LA,Glassman AB,Luthra R,Hayes KJ,Romaguera JE,Cabanillas FF,Medeiros LJ

更新日期：2000-08-01 00:00:00

abstract：Objectives:Diagnosis of B-cell acute lymphoblastic leukemia (B-ALL) requires immunophenotypic evidence of B-lineage and absence of specific myeloid or T-lineage markers. Rare cases of otherwise typical B-ALL express myeloperoxidase (MPO) detectable by flow cytometry with an absence of other myeloid markers, but the cli...

journal_title：American journal of clinical pathology

authors： Oberley MJ,Li S,Orgel E,Phei Wee C,Hagiya A,O'Gorman MRG

更新日期：2017-04-01 00:00:00

abstract：:B5 fixation achieves superior morphologic detail. However, environmental concerns have led to labor-intensive and costly requirements for disposal of mercury-containing fixatives. We performed a blinded prospective study to find a safe, mercury-free alternative to B5. Morphology was evaluated with 6 fixatives, includi...

journal_title：American journal of clinical pathology

authors： Bonds LA,Barnes P,Foucar K,Sever CE

更新日期：2005-08-01 00:00:00

abstract：:The expression of HLA class I antigens in testicular germ cell tumors (TGCTs) was studied by the immunoperoxidase technique. In the normal testicle, the interstitial cells of Leydig as well as most of the germ cells were significantly stained. In typical seminoma, 75% of the tumor cells in stage I and 30% in stage II ...

journal_title：American journal of clinical pathology

authors： Klein B,Klein T,Konichezky M,Nyska A,Livini E,Levine I,Zamir R,Kooperman O,Lurie H

更新日期：1990-02-01 00:00:00

abstract：:Histologic findings in liver biopsy specimens obtained from 88 patients before and one and two years after end-to-end jejunoileal bypass are compared. In addition to the expected fatty changes, mild changes of centrilobular, pericellular fibrosis were present in the initial biopsies in 8.6%; a year later they had beco...

journal_title：American journal of clinical pathology

authors： Marubbio AT Jr,Buchwald H,Schwartz MZ,Varco R

更新日期：1976-10-01 00:00:00