Primary diagnosis of whipple disease manifesting as lymphadenopathy: use of polymerase chain reaction for detection of Tropheryma whippelii.

abstract：:We studied the presence of surfactant protein A (Sp-A) immunoreactivity and messenger RNA in 62 normal and abnormal breast samples. Sections were immunostained with polyclonal anti-Sp-A antibody. The association between Sp-A immunoreactivity and histologic grade of 32 invasive ductal carcinomas was assessed by 3 patho...

journal_title：American journal of clinical pathology

authors： Braidotti P,Cigala C,Graziani D,Del Curto B,Dessy E,Coggi G,Bosari S,Pietra GG

更新日期：2001-11-01 00:00:00

abstract：:We obtained data on laboratory turnaround time (TAT) and emergency department (ED) length of stay (LOS). We correlated potassium test TAT outlier percentage (TAT-OP) with ED LOS and found that for each outlier percentage (potassium result > 40 minutes), a projected impact on ED LOS was approximately 2.8 additional min...

journal_title：American journal of clinical pathology

authors： Holland LL,Smith LL,Blick KE

更新日期：2006-05-01 00:00:00

abstract：:In patients infected with HIV, high-grade B-cell non-Hodgkin's lymphomas (NHL), including the small noncleaved cell (SNCC) category, exhibit pleomorphic features, which makes precise definition difficult. Sixty-nine pathologic specimens with HIV-related systemic lymphomas, including 42 SNCC, 20 immunoblastic lymphomas...

journal_title：American journal of clinical pathology

authors： Carbone A,Gloghini A,Gaidano G,Cilia AM,Bassi P,Polito P,Vaccher E,Saglio G,Tirelli U

更新日期：1995-05-01 00:00:00

abstract：:Cell counter-based formulas have been used in the differential diagnosis of microcytic anemia. The measurement of RBC subpopulations is now available on the Sysmex XE 5000 analyzer (Sysmex, Kobe, Japan). We describe the new formulas: % microcytic - % hypochromic; and % microcytic - % hypochromic - red cell distributio...

journal_title：American journal of clinical pathology

authors： Urrechaga E,Borque L,Escanero JF

更新日期：2011-03-01 00:00:00

abstract：:Analysis of the data for the 1969 to 1973 CAP Surveys of proficiency in partial thromboplastin time (PTT) determination indicates more than desirable variability in this measurement. Non-activated procedures show greater interlaboratory variability than activated methods; therefore, they may be preferable for routine ...

journal_title：American journal of clinical pathology

authors： Koepke JA

更新日期：1975-06-01 00:00:00

abstract：OBJECTIVES:To compare thromboelastography (TEG) tracings obtained from fresh and citrated whole-blood samples in patients on extracorporeal membrane oxygenation (ECMO) or after cardiopulmonary bypass and in healthy volunteers. METHODS:Samples of fresh and citrated whole blood were analyzed for 25 patients and 4 health...

journal_title：American journal of clinical pathology

authors： Gilman EA,Koch CD,Santrach PJ,Schears GJ,Karon BS

更新日期：2013-08-01 00:00:00

abstract：:In five patients with eosinophilia and myeloproliferative disorders, the IgE levels were normal, and immune complexes were not detected. In contrast, in six patients with reactive eosinophilia accompanying immunologic diseases, the IgE levels were elevated in five, and immune complexes were elevated in two. Five of si...

journal_title：American journal of clinical pathology

authors： Crowley JP,Myers TJ

更新日期：1983-03-01 00:00:00

abstract：:A 39-year-old woman with a primary carcinoid of the common bile duct is presented. The tumor showed argyrophilia; and, by immunohistochemical studies, chromogranin, serotonin, and somatostatin were demonstrated. The patient has no symptoms 42 months after surgical treatment. To the authors' knowledge, this is the firs...

journal_title：American journal of clinical pathology

authors： Angeles-Angeles A,Quintanilla-Martínez L,Larriva-Sahd J

更新日期：1991-09-01 00:00:00

abstract：:An unusual case of acute myelomonocytic leukemia (AMML) in an 81-year-old man is described. Ultrastructural examination revealed the presence of distinct Auer bodies, which commonly are found in acute promyelocytic leukemia (APL). The Auer bodies had a splinterlike appearance with a distinct tubular substructure. The ...

journal_title：American journal of clinical pathology

authors： Payne CM,Harrow EJ

更新日期：1983-08-01 00:00:00

abstract：:Under carefully controlled conditions in a clinical research ward, conjugated primary bile-acid concentrations were measured by a 125I-radioimmunoassay every eight hours for four days in seven healthy control subjects and ten patients with hepatic disease (five with cirrhosis, three with primary biliary cirrhosis and ...

journal_title：American journal of clinical pathology

authors： Engelking LR,Dasher CA,Hirschowitz BI

更新日期：1980-02-01 00:00:00

abstract：:Respiratory syncytial virus is detected in cell culture by the presence of cytopathic effect. To detect RSV before cytopathic effect is usually seen, slides were evaluated retrospectively from 482 HEp-2 cell cultures on days 2-4 after inoculation. Indirect immunofluorescent staining detected RSV in 57 of 94 cultures t...

journal_title：American journal of clinical pathology

authors： Bromberg K,Tannis G,Daidone B

更新日期：1991-07-01 00:00:00

abstract：:Platelet function testing is important for the diagnostic evaluation of common and rare bleeding disorders. Our study goals were to promote best practices and reduce unnecessary testing variances by developing North American guidelines on platelet function testing. Guidelines were developed by consensus for expert rec...

journal_title：American journal of clinical pathology

authors： Hayward CP,Moffat KA,Raby A,Israels S,Plumhoff E,Flynn G,Zehnder JL

更新日期：2010-12-01 00:00:00

abstract：:Cultures from the gallbladder and blood of a 60-year-old man with acute cholecystitis grew Haemophilus aphrophilus. This organism, an unusual isolate in clinical specimens, is most frequently seen in patients with either endocarditis or brain abscesses. Haemophilus aphrophilus may be distinguished from Eikenella corro...

journal_title：American journal of clinical pathology

authors： Huck W,Britt MR

更新日期：1978-03-01 00:00:00

abstract：OBJECTIVES:Pure erythroid leukemia (PEL) is exceptionally rare in the pediatric setting. Four pediatric PEL cases with t(1;16)(p31;q24) NFIA-CBFA2T3 were reported previously. We present a case of an infant with PEL presenting with erythroblastic sarcoma and harboring a novel t(1;8)(p31.3;q21.3) NFIA-RUNX1T1 fusion dete...

journal_title：American journal of clinical pathology

authors： King RL,Siaghani PJ,Wong K,Edlefsen K,Shane L,Howard MT,Reichard KK,Mai M,Viswanatha DS,Greipp PT,Goble TA,Ruiz M,Hara H

更新日期：2020-12-14 00:00:00

abstract：:Several technics are currently being used to detect hepatitis type A antigen or its antibody. These include immunoelectronmicroscopy, immune adherence, and complement fixation. This paper describes another promising technic, a microtiter solid-phase immunoradiometric assay, in which hepatitis A antigen and antibody ar...

journal_title：American journal of clinical pathology

authors： Hollinger FB,Bradley DW,Dreesman GR,Melnick JL

更新日期：1976-05-01 00:00:00

abstract：:Estrogen receptor (ER), progesterone receptor (PR), and c-ERBB2 (HER2/neu) are therapeutically and prognostically important markers in the management of breast carcinoma. They are not always analyzed in distant metastatic and locally recurrent breast cancers. We compared immunohistochemical expression in a series of p...

journal_title：American journal of clinical pathology

authors： Idirisinghe PK,Thike AA,Cheok PY,Tse GM,Lui PC,Fook-Chong S,Wong NS,Tan PH

更新日期：2010-03-01 00:00:00

abstract：:Tissue repositories maintained by pathology departments represent an abundant resource of clinically annotated human specimens. The storage expenses associated with pathology archives are known to administrators of most pathology departments. However, such basic repository characteristics as the quality of stored mate...

journal_title：American journal of clinical pathology

authors： Smith MA,Barnes EL,Chiosea SI

更新日期：2011-05-01 00:00:00

abstract：:The determination of tumor cell estrogen receptor (ER) expression status by immunohistochemical analysis has become standard practice, yet assay reproducibility has not been assessed adequately. By using a breast cancer tissue microarray, we examined interlaboratory variability in ER reporting. A 2-fold redundant tiss...

journal_title：American journal of clinical pathology

authors： Parker RL,Huntsman DG,Lesack DW,Cupples JB,Grant DR,Akbari M,Gilks CB

更新日期：2002-05-01 00:00:00

abstract：:Determination of breast cancer estrogen receptor (ER) status as a predictor of tumor response to adjuvant endocrine therapy remains a mainstay of breast cancer management. Recent second generation anti-ER antibodies and new epitope retrieval methods have produced paraffin-based immunohistochemical results that correla...

journal_title：American journal of clinical pathology

authors： Nichols GE,Frierson HF Jr,Boyd JC,Hanigan MH

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVES:Myeloid and lymphoid neoplasms with abnormalities of fibroblast growth factor receptor 1 gene (FGFR1) are a rare and aggressive disease group that harbors translocations of FGFR1 with at least 14 recognized partner genes. We report a case of a patient with a novel t(17;21)(p13;q22) with RUNX1 rearrangement a...

journal_title：American journal of clinical pathology

authors： Kumar KR,Chen W,Koduru PR,Luu HS

更新日期：2015-05-01 00:00:00

abstract：:Multicentric osteosarcoma (M-OGS) is characterized by multicentricity of osseous osteosarcomas, either synchronous or metachronous, without visceral involvement. The study's purpose was to clinicopathologically and radiographically analyze 56 cases of M-OGS (22 synchronous and 34 metachronous). The distal femur was th...

journal_title：American journal of clinical pathology

authors： Corradi D,Wenger DE,Bertoni F,Bacchini P,Bosio S,Goldoni M,Unni KK,Sim FH,Inwards CY

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:To evaluate the clinical utility of and demand for the creatine kinase (CK)-MB assay. METHODS:We examined the number of CK-MB tests from 2007 through 2013 while we progressively deemphasized their use. We first removed CK-MB from the acute coronary syndrome (ACS) panel and then from the main menu and observ...

journal_title：American journal of clinical pathology

authors： Singh G,Baweja PS

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:Mucinous cystic neoplasm of the liver is characterized by neoplastic mucinous and/or biliary epithelium surrounded by ovarian-type stroma. Immunohistochemical studies have shown that the ovarian-type stroma expresses estrogen receptor, suggesting potential hormonal responsiveness. The molecular biology of mu...

journal_title：American journal of clinical pathology

authors： Van Treeck BJ,Lotfalla M,Czeczok TW,Mounajjed T,Moreira RK,Allende DS,Reid MD,Naini BV,Westerhoff M,Adsay NV,Kerr SE,Rizvi SH,Smoot RL,Liu Y,Davila J,Graham RP

更新日期：2020-11-04 00:00:00

abstract：:The diagnostic expert system for colonic lesions (DESCL) was designed to discriminate colonic adenoma and adenocarcinoma from normal colonic tissue. Although it was originally developed for use in conjunction with a machine vision analytic system, the DESCL has evolved into a teaching tool and a model for conceptual m...

journal_title：American journal of clinical pathology

authors： Graham AR,Paplanus SH,Bartels PH

更新日期：1990-10-01 00:00:00

abstract：:Interest in the role of mononuclear phagocytes in glomerulonephritis (GN) and in defining markers of renal neoplasms led the authors to study alpha-naphthyl acetate/butyrate esterase (ANAE/ANBE), alkaline phosphatase (AlkP), acid phosphatase (AcP), 5'-nucleotidase (5'N), and ATPase (ATP) activity in paraformaldehyde-f...

journal_title：American journal of clinical pathology

authors： Alpers CE,Beckstead JH

更新日期：1985-05-01 00:00:00

abstract：:Since the introduction of the triple screen, the emergence of additional analytes found to be associated with trisomy 21 pregnancies has challenged the clinical pathology and obstetric communities to determine which combination provides the best performance characteristics as a screening test. The cost, practicality, ...

journal_title：American journal of clinical pathology

authors： Baliff JP,Mooney RA

更新日期：2003-12-01 00:00:00

abstract：:Four cases of acute myelofibrosis are contrasted to three cases of acute megakaryocytic leukemia. The cases were clinically indistinguishable. Light microscopic examination of hematoxylin and eosin-stained bone marrow biopsy specimens from the cases of acute myelofibrosis showed a trilinear proliferation of mature and...

journal_title：American journal of clinical pathology

authors： Hruban RH,Kuhajda FP,Mann RB

更新日期：1987-11-01 00:00:00

abstract：OBJECTIVES:Serologic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has experienced a changing landscape of available assays coupled with uncertainty surrounding performance characteristics. Studies are needed to directly compare multiple commercially available assays. METHODS:Residual serum ...

journal_title：American journal of clinical pathology

authors： Manthei DM,Whalen JF,Schroeder LF,Sinay AM,Li SH,Valdez R,Giacherio DA,Gherasim C

更新日期：2020-10-09 00:00:00

abstract：:Oxidized low-density lipoprotein (oxLDL)/beta(2)-glycoprotein I (beta2GPI) complexes have been implicated in atherogenesis. oxLDL/beta2GPI complexes were measured in 339 patients with suspected acute coronary syndromes. Approximately 68% had angiographically documented coronary artery disease (CAD) and significantly h...

journal_title：American journal of clinical pathology

authors： Greco TP,Conti-Kelly AM,Anthony JR,Greco T Jr,Doyle R,Boisen M,Kojima K,Matsuura E,Lopez LR

更新日期：2010-05-01 00:00:00

abstract：:Experiences of the CAP Survey Program in reticulocyte counts and morphologic identification of reticulocytes from 1971 to 1974 are reviewed. Problems of morphologic identification are reflected in an excessive variance of reticulocyte counts. Statistical sources of variations in counting are identified. The older, ori...

journal_title：American journal of clinical pathology

authors： Gilmer PR Jr,Koepke JA

更新日期：1976-07-01 00:00:00