Pathology archive: evaluation of integrity, regulatory compliance, and construction of searchable database from print reports.

abstract：:We examined the occurrence of JAK2(V617F) and JAK2 exon 12 mutations in a clinical cohort of polycythemia vera (PV) in Taiwan. Of 22 patients with PV, 17 (77%) had the V617F mutation, and all 5 V617F-negative patients (23%) had the exon 12 mutation. We found 3 different exon 12 mutations: 3 N542-E543del, 1 F537-K539de...

journal_title：American journal of clinical pathology

authors： Yeh YM,Chen YL,Cheng HY,Su WC,Chow NH,Chen TY,Ho CL

更新日期：2010-08-01 00:00:00

abstract：:In view of their reported reciprocal effects on apoptosis, the expression of p53 and bcl-2 proteins was studied in 46 cases of Hodgkin's disease by immunocytochemical labeling. We found p53 protein in Reed-Sternberg cells and their mononuclear variants in 16 of the 46 cases (34.7%) of Hodgkin's disease, mainly in a nu...

journal_title：American journal of clinical pathology

authors： Doussis IA,Pezzella F,Lane DP,Gatter KC,Mason DY

更新日期：1993-06-01 00:00:00

abstract：:Evaluation of blood cells to determine immunologic status is becoming an important clinical application of flow cytometric analysis. For a wider use of immunophenotyping technology in clinical laboratories, the authors developed a rapid method to detect monoclonal antibody-labeled cells using forward light scatter/abs...

journal_title：American journal of clinical pathology

authors： Kim YR,Paseltiner L,Kling G,Yeh CK

更新日期：1992-03-01 00:00:00

abstract：Objectives:A report on the multicenter evaluation of the Bruker MALDI Biotyper CA System (MBT-CA; Bruker Daltonics, Billerica, MA) for the identification of clinically important bacteria and yeasts. Methods:In total, 4,399 isolates of medically important bacteria and yeasts were assessed in the MBT-CA. These included ...

journal_title：American journal of clinical pathology

authors： Wilson DA,Young S,Timm K,Novak-Weekley S,Marlowe EM,Madisen N,Lillie JL,Ledeboer NA,Smith R,Hyke J,Griego-Fullbright C,Jim P,Granato PA,Faron ML,Cumpio J,Buchan BW,Procop GW

更新日期：2017-06-01 00:00:00

abstract：:This report describes the selective staining of lysosomes in cells of neutrophilic granulocytic origin by the azo textile dye basic blue 93. Used as a single agent aqueous stain after fixation, the dye stained lysosomes black. Stained in this way, lysosomes were sharply delimited and easily visualized. Large numbers o...

journal_title：American journal of clinical pathology

authors： Kass L

更新日期：1988-02-01 00:00:00

abstract：:Primary thymic epithelial neoplasms have been the subject of much controversy in recent years owing to the difficulties posed by these tumors for precise histopathologic typing and prognostication. A number of classification schemes using different terminology have been proposed, none of which has satisfactorily manag...

journal_title：American journal of clinical pathology

authors： Suster S,Moran CA

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVES:Our aim was to investigate the frequency of steatohepatitic morphology in hepatocellular adenoma (HCA) and correlate with its clinical parameters and risk factors underlying nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH). METHODS:We examined a series of 41 liver resection sp...

journal_title：American journal of clinical pathology

authors： Liu Y,Zen Y,Yeh MM

更新日期：2020-09-08 00:00:00

abstract：:The determination of tumor cell estrogen receptor (ER) expression status by immunohistochemical analysis has become standard practice, yet assay reproducibility has not been assessed adequately. By using a breast cancer tissue microarray, we examined interlaboratory variability in ER reporting. A 2-fold redundant tiss...

journal_title：American journal of clinical pathology

authors： Parker RL,Huntsman DG,Lesack DW,Cupples JB,Grant DR,Akbari M,Gilks CB

更新日期：2002-05-01 00:00:00

abstract：:Neutrophil function was determined in resting and phagocytic cells by an assay of hexose monophosphate shunt activity performed on small volumes of whole blood. This new micromethod clearly differentiated between zymosan-stimulated and unstimulated hexose monophosphate shunt activity. Furthermore, the whole blood micr...

journal_title：American journal of clinical pathology

authors： King JW,McCall CE

更新日期：1980-07-01 00:00:00

abstract：:To study the distribution and thromboembolic effect of Ultrafluid Lipiodol, 15 surgically removed hepatocellular carcinomas with selective intraarterial Lipiodol injection 7 to 10 days before surgery and 15 noninjected controls were studied radiologically and histologically. Tissue blocks were processed with an en blo...

journal_title：American journal of clinical pathology

authors： Arnold MM,Kreel L,Wallace AC,Li AK

更新日期：1992-03-01 00:00:00

abstract：:A 65-year-old man with lower back pain was found to have multiple myeloma. Unique findings in the marrow aspirate smears of this patient were tadpolelike plasma cells and cellular rosettes simulating those seen in neuroblastoma. This case documents yet another facet of the broad morphologic spectrum of neoplastic plas...

journal_title：American journal of clinical pathology

authors： Wong KF,Chan JK,Chu YC

更新日期：1992-12-01 00:00:00

abstract：:Immunohistochemical analysis of oral lichen-planus-like eruption (LPLE) in graft-versus-host disease (GVHD) using monoclonal antibodies (MoAbs) was performed on five patients after allogeneic bone marrow transplantation (BMT) for leukemia. In the mucosal lesions of LPLE in GVHD, the major population of infiltrated lym...

journal_title：American journal of clinical pathology

authors： Fujii H,Ohashi M,Nagura H

更新日期：1988-02-01 00:00:00

abstract：:This paper presents the first comprehensive morphometry analysis of normal thyroid, adenomas, and follicular and papillary carcinomas. The mean nuclear volume and the mean nuclear surface increased, while the volume densities of rough endoplasmic reticulum and dense bodies decreased from normal thyroid through adenoma...

journal_title：American journal of clinical pathology

authors： Johannessen JV,Sobrinho-Simóes M,Finseth I,Pilström L

更新日期：1983-02-01 00:00:00

abstract：OBJECTIVES:Bladder cancers invading the muscularis mucosae (MM) are treated differently from those invading the muscularis propria (MP). However, it may be difficult to determine the type of smooth muscle in transurethral resection (TUR) or biopsy specimens. We aimed to investigate the clinicopathologic features of bla...

journal_title：American journal of clinical pathology

authors： Hwang MJ,Kamat AM,Dinney CP,Czerniak B,Guo CC

更新日期：2020-07-07 00:00:00

abstract：:A case of subclinical hemolytic disease of the newborn resulting in reticulocytosis and positive direct and indirect antiglobulin tests in an infant both ABO- and Rh(D)-compatible with its mother is reported. The antibody was an IgG, non-complement-binding molecule present in low titer with a low avidity for the antig...

journal_title：American journal of clinical pathology

authors： Hanzlick RL,Senhauser DA

更新日期：1979-07-01 00:00:00

abstract：OBJECTIVES:To differentiate the leprosy agents Mycobacterium leprae and Mycobacterium lepromatosis and correlate them with geographic distribution and clinicopathologic features. METHODS:Species-specific polymerase chain reactions were used to detect each bacillus in archived skin biopsy specimens from patients with l...

journal_title：American journal of clinical pathology

authors： Han XY,Aung FM,Choon SE,Werner B

更新日期：2014-10-01 00:00:00

abstract：:Oxidized low-density lipoprotein (oxLDL)/beta(2)-glycoprotein I (beta2GPI) complexes have been implicated in atherogenesis. oxLDL/beta2GPI complexes were measured in 339 patients with suspected acute coronary syndromes. Approximately 68% had angiographically documented coronary artery disease (CAD) and significantly h...

journal_title：American journal of clinical pathology

authors： Greco TP,Conti-Kelly AM,Anthony JR,Greco T Jr,Doyle R,Boisen M,Kojima K,Matsuura E,Lopez LR

更新日期：2010-05-01 00:00:00

abstract：:Primary gastric non-Hodgkin lymphoma of mucosa-associated lymphoid tissue (MALT-NHL) is strongly related to Helicobacter pylori (H pylori) infection. CagA positive H pylori strains appear to be more aggressive, as reflected by a greater degree of gastric inflammation and higher levels of Il-8 production. Using a polym...

journal_title：American journal of clinical pathology

authors： de Jong D,van der Hulst RW,Pals G,van Dijk WC,van der Ende A,Tytgat GN,Taal BG,Boot H

更新日期：1996-11-01 00:00:00

abstract：:Timely communication of significant or unexpected findings in surgical pathology can significantly improve patient care. Although surgical pathology critical values have been published, no systematic assessment in pediatric surgical pathology has been published. We surveyed pediatric pathologists and pediatric subspec...

journal_title：American journal of clinical pathology

authors： Coffin CM,Spilker K,Lowichik A,Zhou H,Nielson K,Erickson L,Pysher TJ

更新日期：2007-12-01 00:00:00

abstract：:The clinical microscopy (fluids) laboratory evaluates almost every body fluid that is obtained in the hospital. Because the fluids laboratory functions at all hours, it is often the first laboratory to receive a body fluid. In addition to its primary purpose of quantitating categories of cells, the medical technologis...

journal_title：American journal of clinical pathology

authors： Ben-Ezra J,Stastny JF,Harris AC,Bork L,Frable WJ

更新日期：1994-10-01 00:00:00

abstract：:An aggressive visceral form of Kaposi's sarcoma (KS) has been reported in immunosuppressed populations, most notably in patients with acquired immunodeficiency syndrome (AIDS). This presentation contrasts from the indolent skin lesions on the extremities of older males and is distinct enough in the young adult America...

journal_title：American journal of clinical pathology

authors： Berman MA,Nalesnik MA,Kapadia SB,Rinaldo CR Jr,Jensen F

更新日期：1986-09-01 00:00:00

abstract：:Lean methodologies have been applied in many industries to reduce waste. We applied Lean techniques to redesign laboratory workstations with the aim of reducing the number of times employees must leave their workstations to complete their tasks. At baseline in 68 workflows (aggregates or sequence of process steps) stu...

journal_title：American journal of clinical pathology

authors： Yerian LM,Seestadt JA,Gomez ER,Marchant KK

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:Human epidermal growth factor receptor 2 (HER2, ERBB2) testing is an important prognostic/predictive marker in breast cancer management, especially in selecting HER2-targeted treatment. American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) guidelines address HER2 status and were...

journal_title：American journal of clinical pathology

authors： Long TH,Lawce H,Durum C,Moore SR,Olson SB,Gatter K,Troxell ML

更新日期：2015-08-01 00:00:00

abstract：:A man was hospitalized with bacteremic Achromobacter xylosoxidans type IIIa pneumonia. The authors are aware of no previously reported similar infections caused by this bacterium. A clinical cure was achieved with a combination of carbenicillin and kanamycin therapy. Microtiter susceptibility testing revealed that car...

journal_title：American journal of clinical pathology

authors： Dworzack DL,Murray CM,Hodges GR,Barnes WG

更新日期：1978-10-01 00:00:00

abstract：:Most cutaneous T-cell lymphomas are derived from mature postthymic T cells of the CD4 subtype. When other less common profiles are encountered, a diagnostic challenge is posed. Accurate categorization is critical because of the specificity of therapeutic regimens, including biologics. A 65-year-old woman was seen in 2...

journal_title：American journal of clinical pathology

authors： Magro CM,Seilstad KH,Porcu P,Morrison CD

更新日期：2006-07-01 00:00:00

abstract：:We describe 2 male patients in whom hepatosplenic gamma/delta T-cell lymphoma (HSTL) developed 6 and 10 years after renal transplantation. The onset was abrupt with systemic symptoms, cytopenia, and hepatosplenomegaly. The histologic examination of the spleen (case 1), liver, and bone marrow revealed sinusoidal infilt...

journal_title：American journal of clinical pathology

authors： Khan WA,Yu L,Eisenbrey AB,Crisan D,al Saadi A,Davis BH,Hankin RC,Mattson JC

更新日期：2001-07-01 00:00:00

abstract：:Pseudo-Pelger-Huët anomaly (PPHA) has been documented in association with transplant medications and other drugs. This iatrogenic neutrophilic dysplasia is reversible with cessation or adjustment of medications but is frequently confused with myelodysplastic syndrome (MDS) based on the conventional concept that PPHA i...

journal_title：American journal of clinical pathology

authors： Wang E,Boswell E,Siddiqi I,Lu CM,Sebastian S,Rehder C,Huang Q

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVES:Blood component waste is an important issue at all hospitals. As an initiative of the patient blood management program at a regional health care system, the causes and extent of blood product wastage were identified, and targeted interventions to effect a reduction were implemented. METHODS:Multiple low-cos...

journal_title：American journal of clinical pathology

authors： Collins RA,Wisniewski MK,Waters JH,Triulzi DJ,Yazer MH

更新日期：2015-03-01 00:00:00

abstract：:Previous studies of patients with lymphoid malignancies have suggested a relationship between survival and the presence of more than 40% hard-mirror cells in the bone marrow. This report represents the first detailed study of a patient with American Burkitt's lymphoma with numerous hand-mirror cells in the bone marrow...

journal_title：American journal of clinical pathology

authors： Schumacher HR,Rainey T,Davidson L,Simon D,Strong M,Creegan WJ,Holloway ML,Stass SA

更新日期：1978-12-01 00:00:00

abstract：:While plasmacytosis is a common occurrence in early post-bone marrow transplantation biopsy specimens, the significance of plasma cells in such specimens from patients with multiple myeloma (MM) is unknown. We attempted to retrospectively determine, by morphologic assessment of plasma cell percentage, immunohistologic...

journal_title：American journal of clinical pathology

authors： Maia DM,Kell DL,Goates JJ,Warnke RA

更新日期：1997-06-01 00:00:00