Multiple myeloma with tadpolelike cells and rosette formation.

abstract：:Congenital-infantile fibrosarcoma (CIFS) is a relatively indolent sarcoma that should be distinguished from more aggressive spindle cell sarcomas of childhood. CIFSs have been found to have a novel recurrent reciprocal translocation t(12;15)(p13;q25) resulting in the gene fusion ETV6-NTRK3 (ETS variant gene 6; neurotr...

journal_title：American journal of clinical pathology

authors： Sheng WQ,Hisaoka M,Okamoto S,Tanaka A,Meis-Kindblom JM,Kindblom LG,Ishida T,Nojima T,Hashimoto H

更新日期：2001-03-01 00:00:00

abstract：:Fresh frozen plasma (FFP) normally requires about 45 min to thaw in a 37 degrees C water bath when placed inside an additional plastic overbag. That relatively prolonged time may result in non-utilization or delays in delivery of the product, especially, during emergency surgery. One report recommends the use of a mic...

journal_title：American journal of clinical pathology

authors： Westphal RG,Tindle B,Howard PL,Golden EA,Page GA

更新日期：1982-08-01 00:00:00

abstract：:We surveyed 271 laboratories participating in a quality assessment program to ascertain whether the use of a calibration curve for determining the international normalized ratio (INR) would improve interlaboratory accuracy and precision. Lyophilized warfarinized samples with INR values assigned through manual calibrat...

journal_title：American journal of clinical pathology

authors： Brien WF,Baskerville JC,Taberner DA,Crawford L

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVES:To examine laser microdissection and mass spectrometry (LMD-MS), which has emerged as a new tool to aid in typing amyloid proteins. RESULTS:ALECT-2 is a potential cause of hepatic amyloidosis best detected by LMD-MS. METHODS:One of the more recently reported proteins is ALECT-2 (leukocyte cell-derived chem...

journal_title：American journal of clinical pathology

authors： Damlaj M,Amre R,Wong P,How J

更新日期：2014-02-01 00:00:00

abstract：:With various methods, BRAF mutations have been detected in 73.4% to 87.1% of papillary thyroid carcinomas (PTCs) in Korea. We assessed the ability of allele-specific polymerase chain reaction using a dual priming oligonucleotide system, compared with direct sequencing and pyrosequencing, to detect BRAF mutations in fi...

journal_title：American journal of clinical pathology

authors： Lee HJ,Choi J,Hwang TS,Shong YK,Hong SJ,Gong G

更新日期：2010-05-01 00:00:00

abstract：:Cellular and humoral immunity combine to determine the outcome following exposure to hepatitis virus and are implicated in the proposed pathogenetic mechanism for acute and chronic hepatitis. Although antibody to HBsAg is found in virtually all following recovery from hepatitis B, a cell-mediated response to HBsAg can...

journal_title：American journal of clinical pathology

authors： Lee WM

更新日期：1976-05-01 00:00:00

abstract：:The diagnostic value of glypican 3 (GPC3) immunostaining on needle biopsy specimens has not been well assessed. In this study, 120 liver needle biopsy specimens, including 46 from cirrhotic livers and 74 hepatocellular carcinomas (HCCs), were immunohistochemically examined for expression of GPC3. The results showed st...

journal_title：American journal of clinical pathology

authors： Anatelli F,Chuang ST,Yang XJ,Wang HL

更新日期：2008-08-01 00:00:00

abstract：:Sex cord tumor with annular tubules (SCTAT) is a distinctive ovarian sex cord-stromal tumor. The authors describe a case of SCTAT arising outside the ovaries, in the fallopian tube. The authors are aware of only one other case of extra-ovarian SCTAT, in an umbilical hernia sac in an adult woman. The case reported was ...

journal_title：American journal of clinical pathology

authors： Griffith LM,Carcangiu ML

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVES:Sentinel lymph node (SLN)-based diagnosis in gastric cancers has shown varied sensitivities and false-negative rates in several studies. Application of the reverse transcription-polymerase chain reaction (RT-PCR) in SLN diagnosis has recently been proposed. METHODS:A total of 155 SLNs from 65 patients with ...

journal_title：American journal of clinical pathology

authors： Kwak Y,Nam SK,Shin E,Ahn SH,Lee HE,Park do J,Kim WH,Kim HH,Lee HS

更新日期：2016-05-01 00:00:00

abstract：:A 39-year-old woman with a primary carcinoid of the common bile duct is presented. The tumor showed argyrophilia; and, by immunohistochemical studies, chromogranin, serotonin, and somatostatin were demonstrated. The patient has no symptoms 42 months after surgical treatment. To the authors' knowledge, this is the firs...

journal_title：American journal of clinical pathology

authors： Angeles-Angeles A,Quintanilla-Martínez L,Larriva-Sahd J

更新日期：1991-09-01 00:00:00

abstract：:Haemophilus influenzae type b, Escherichia coli, Neisseria meningitis, Streptococcus agalactiae, and Streptococcus pneumoniae are classically the predominant meningeal pathogens of children. The Directigen latex agglutination test identifies these pathogens by detecting specific antigens in cerebrospinal fluid (CSF) a...

journal_title：American journal of clinical pathology

authors： Hill RB,Adams S,Gunn BA,Eberly BJ

更新日期：1994-06-01 00:00:00

abstract：:Infusible platelet membranes (IPMs) prepared from fresh or outdated human platelets have been shown to correct prolonged bleeding times in thrombocytopenic rabbits. In previous trials, IPMs did not seem to be immunogenic and lacked dose-limiting toxicity. The present study was undertaken to explore whether the platele...

journal_title：American journal of clinical pathology

authors： Graham SS,Gonchoroff NJ,Miller JL

更新日期：2001-01-01 00:00:00

abstract：:Centerin (SERPINA9/GCET1) is a protease inhibitor with expression restricted to germinal center B cells and lymphoid malignancies with germinal center B-cell maturation. Expression of the centerin gene transcript, along with bcl-6 and GCET2/HGAL, constitutes a molecular signature associated with a good prognosis in di...

journal_title：American journal of clinical pathology

authors： Paterson MA,Hosking PS,Coughlin PB

更新日期：2008-07-01 00:00:00

abstract：:We further characterize the heterogeneous carcinomas of the papilla of Vater (CPVs) in relation to various clinicopathologic patient characteristics and patient survival. Of the 71 reevaluated CPVs, 32 were intestinal, 26 were pancreatobiliary, 6 were mixed, 4 were mucinous, and 3 were poorly differentiated carcinomas...

journal_title：American journal of clinical pathology

authors： Kohler I,Jacob D,Budzies J,Lehmann A,Weichert W,Schulz S,Neuhaus P,Röcken C

更新日期：2011-02-01 00:00:00

abstract：:A case of fetal demise and maternal recovery after acetaminophen overdose is presented, to our knowledge the first reported. Fetal liver and maternal serum concentrations indicate overdose to be the cause of fetal death. Maternal disseminated intravascular coagulation (DIC) may have been related to maternal acetaminop...

journal_title：American journal of clinical pathology

authors： Haibach H,Akhter JE,Muscato MS,Cary PL,Hoffmann MF

更新日期：1984-08-01 00:00:00

abstract：:Seventeen tubular carcinomas occurred among 211 consecutive mastectomies (7.6%). The relative frequencies of multicentric involvement in the ipsilateral breast (56%), history of bilateral mammary cancer (38%) (P less than .01), and family history of mammary cancer in a first-degree relative (40%) (P less than .05) wer...

journal_title：American journal of clinical pathology

authors： Lagios MD,Rose MR,Margolin FR

更新日期：1980-01-01 00:00:00

abstract：:The authors have assessed the clinical value of an "accurate" band count as a correlate to infection in 33 patients with a culture proven bacterial infection and a normal total leukocyte count. Thirty hematologically normal outpatients, presumably with no infections, were selected for the control group. Manual 500 cel...

journal_title：American journal of clinical pathology

authors： Ardron MJ,Westengard JC,Dutcher TF

更新日期：1994-11-01 00:00:00

abstract：:Two unusual cases of acute lymphoblastic leukemia-hand mirror variant (ALL-HMV) are presented. One patient demonstrated a mixed immunophenotype with HLA-DR, My7, transferrin receptor surface markers, and terminal deoxynucleotidyl transferase positivity. To the authors' knowledge, this is the first ALL-HMV reported wit...

journal_title：American journal of clinical pathology

authors： Schumacher HR,Desai SN,McClain KL,Domenico DR,Dizikes GJ,Bird ML

更新日期：1989-04-01 00:00:00

abstract：:Two atypical human non-Hodgkin's lymphomas (NHLs) that exhibited unusual genotypic and in situ immunophenotypic abnormalities are described. Immunophenotypically, both NHLs lacked surface Ig heavy chains. With the exception of the MB2 B-cell-associated antigen, no B- and T-cell differentiation antigen was detected in ...

journal_title：American journal of clinical pathology

authors： De Re V,Carbone A,Dolcetti R,Tirelli U,Folegotto C,Boiocchi M

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVES:To examine high expression of tumor necrosis factor ligand superfamily member 13 (TNFSF13), which is correlated with several malignancies. METHODS:TNFSF13 messenger RNA expression in tumor cells and fibroblasts in a cohort of patients with non-small cell lung cancer (NSCLC) was analyzed by quantitative real...

journal_title：American journal of clinical pathology

authors： Qian Z,Qingshan C,Chun J,Huijun Z,Feng L,Qiang W,Qiang X,Min Z

更新日期：2014-02-01 00:00:00

abstract：:Delta checking is a laboratory information system (LIS)-based tool that detects patient and laboratory quality control errors. By using hemoglobin A1c (HbA1c) data, we developed a novel approach to summarizing and presenting patient Delta values to address limitations of current Delta check algorithms. Delta values we...

journal_title：American journal of clinical pathology

authors： Tran DV,Cembrowski GS,Lee T,Higgins TN

更新日期：2008-08-01 00:00:00

abstract：:An assessment of the infrequently performed protein-bound iodine determinations (PBI) and thyroxine (T4) determinations by column chromatography is presented after analysis of data contributed by participants in the 1976 College of American Pathologists Chemistry Survey Programs. The two technics yield comparable mean...

journal_title：American journal of clinical pathology

authors： Thiessen MM,Batsakis JG,Neuhoff J,Thomas BP

更新日期：1978-09-01 00:00:00

abstract：:Three stillborn fetuses are reported in which an abdominal wall defect was associated with defects in the urogenital and anal region. Autopsy of these fetuses provided clues indicative of how and where the embryonic development went wrong. The malformation involved a disturbance of the cell deposition process, occurri...

journal_title：American journal of clinical pathology

authors： Hartwig NG,Steffelaar JW,Van de Kaa C,Schueler JA,Vermeij-Keers C

更新日期：1991-11-01 00:00:00

abstract：:Pseudo-Pelger-Huët anomaly (PPHA) has been documented in association with transplant medications and other drugs. This iatrogenic neutrophilic dysplasia is reversible with cessation or adjustment of medications but is frequently confused with myelodysplastic syndrome (MDS) based on the conventional concept that PPHA i...

journal_title：American journal of clinical pathology

authors： Wang E,Boswell E,Siddiqi I,Lu CM,Sebastian S,Rehder C,Huang Q

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVES:GATA3 is a transcription factor regulating luminal cell differentiation in the mammary glands and has been implicated in the luminal types of breast carcinoma. The prognostic significance of GATA3 in breast cancer remains controversial. METHODS:In this study, we assessed the prognostic value of the molecule...

journal_title：American journal of clinical pathology

authors： McCleskey BC,Penedo TL,Zhang K,Hameed O,Siegal GP,Wei S

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVES:Peritoneal mesothelial cysts have been reported under various terms, including benign cystic mesothelioma, usually in the form of case reports/series, whereas extraperitoneal cases are rarely reported. Our objective was to report the detailed characteristics of cystic lesions of the serosal cavities. METHOD...

journal_title：American journal of clinical pathology

authors： Karpathiou G,Casteillo F,Dridi M,Peoc'h M

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:Overuse of laboratory tests is a persistent issue. We examined the use and overuse of serum immunofixation electrophoresis and serum free light chain assays to develop an algorithm for optimizing utilization. METHODS:A retrospective review of all tests, for investigation of monoclonal gammopathies, for all ...

journal_title：American journal of clinical pathology

authors： Heaton C,Vyas SG,Singh G

更新日期：2016-04-01 00:00:00

abstract：:Current methods for testing stool samples for hemoglobin utilize peroxidase oxidation of chemical indicators such as guaiac or benzidine. These tests have frequent false-positive and false-negative results, complicating random screening for occult gastrointestinal bleeding. The authors have developed an immunochemical...

journal_title：American journal of clinical pathology

authors： Barrows GH,Burton RM,Jarrett DD,Russell GG,Alford MD,Songster CL

更新日期：1978-03-01 00:00:00

abstract：OBJECTIVES:To determine the impact of implementing p16 Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions (LAST) guidelines, we compared p16 use and follow-up data before and after implementation of the guidelines. METHODS:We reviewed all cervical biopsy specimens diagnosed by two...

journal_title：American journal of clinical pathology

authors： Clinton LK,Miyazaki K,Ayabe A,Davis J,Tauchi-Nishi P,Shimizu D

更新日期：2015-12-01 00:00:00

abstract：:Factitious laboratory results often lead to unnecessary testing or treatment. This brief review of factitious biochemical results due to preexisting hematologic conditions focuses on the mechanisms underlying the factitious results and suggests ways to prevent them. An observant pathologist identifies these errors, in...

journal_title：American journal of clinical pathology

authors： Dalal BI,Brigden ML

更新日期：2009-02-01 00:00:00