Congenital-infantile fibrosarcoma. A clinicopathologic study of 10 cases and molecular detection of the ETV6-NTRK3 fusion transcripts using paraffin-embedded tissues.

abstract：OBJECTIVES:To describe the histopathologic and immunophenotypic features of a temporary splenic allograft exposed to massive donor-specific antibody (DSA) insult. METHODS:A human cadaveric donor splenic allograft was temporarily transplanted in a highly sensitized patient with the intention of removing DSA before inte...

journal_title：American journal of clinical pathology

authors： Gaitonde S,Hassan M,Mehta V,Benedetti E,Tzvetanov I,Lichvar A,Pirzada S,Setty S

更新日期：2020-11-21 00:00:00

abstract：:Seventy-nine mycelial-form stock cultures of Blastomyces dermatitidis, Coccidioides immitis, Histoplasma capsulatum, and morphologically similar fungi were extracted and tested by using commercial macroimmunodiffusion exoantigen test kits and the Centers for Disease Control (CDC) reference system for identifying funga...

journal_title：American journal of clinical pathology

authors： Denys GA,Newman MA,Standard PG

更新日期：1983-03-01 00:00:00

abstract：:Fixed lymphoma tissues from 11 patients seropositive for human T-cell leukemia virus type I (HTLV-I) antibodies were analyzed for proviral sequences by the polymerase chain reaction. Typical adult T-cell leukemia/lymphomas (ATLLs) from nine patients were positive for HTLV-I sequences. In contrast, one of two lymphomas...

journal_title：American journal of clinical pathology

authors： Shibata D,Tokunaga M,Sasaki N,Nanba K

更新日期：1991-04-01 00:00:00

abstract：:This report concerns a particular benign histologic variant of Hodgkin's disease, the lymphocyte-predominant category of the Rye classification. The group of 24 cases, all involving localized disease, was first reported in 1960, and is now reappraised, incorporating subsequent data. The interpretations of the original...

journal_title：American journal of clinical pathology

authors： Wright CJ

更新日期：1977-06-01 00:00:00

abstract：:Platelet factor 4 (PF4)/heparin antibody, typically associated with heparin therapy, is reported in some heparin-naive people. Seroprevalence in the general population, however, remains unclear. We prospectively evaluated PF4/heparin antibody in approximately 4,000 blood bank donors using a commercial enzyme-linked im...

journal_title：American journal of clinical pathology

authors： Hursting MJ,Pai PJ,McCracken JE,Hwang F,Suvarna S,Lokhnygina Y,Bandarenko N,Arepally GM

更新日期：2010-11-01 00:00:00

abstract：:CD45/side scatter (SS) gating is widely used for isolating blasts by flow cytometry (FC). However, other cells contaminate the "blast gate" (BG); CD45/SS gating is thus imprecise, particularly when there are few blasts. We studied the BG contents in 21 myelodysplastic syndromes (MDSs), 14 myeloproliferative neoplasms ...

journal_title：American journal of clinical pathology

authors： Harrington AM,Olteanu H,Kroft SH

更新日期：2012-05-01 00:00:00

abstract：:After several transfusions with D-negative blood, an O Rh-negative women was apparently sensitized to the C and D antigens. In her prenatal workup, it became evident that she had in fact not been sensitized to D but to G, which initially appeared as anti-D plus anti-C. This sensitization pattern is an unusual occurren...

journal_title：American journal of clinical pathology

authors： Yesus YW,Akhter JE

更新日期：1985-12-01 00:00:00

abstract：:A patient with acquired von Willebrand disease associated with multiple myeloma (IgG-lambda) is described. Mixture of his plasma or IgG fraction with washed control platelets resulted in the inhibition of aggregation with ristocetin, but mixture of control plasma or IgG fraction with washed patient platelets showed no...

journal_title：American journal of clinical pathology

authors： Mohri H,Noguchi T,Kodama F,Itoh A,Ohkubo T

更新日期：1987-05-01 00:00:00

abstract：:A number of reports have highlighted discrepancies between the DuPont aca and fibrometer-based methods for quantitating plasma fibrinogen levels. Although many authors have suggested that the presence of fibrin(ogen) degradation products are in some way responsible for the discrepancies, no direct test of this hypothe...

journal_title：American journal of clinical pathology

authors： Hoffman M,Greenberg CS

更新日期：1987-10-01 00:00:00

abstract：:Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a benign lesion of the oral mucosa of an unclear pathogenesis. We analyzed the profile of the inflammatory infiltrate in 12 cases of TUGSE by using immunohistochemical analysis and polymerase chain reaction-based repertoire analysis to detect T- and B...

journal_title：American journal of clinical pathology

authors： Hirshberg A,Amariglio N,Akrish S,Yahalom R,Rosenbaum H,Okon E,Kaplan I

更新日期：2006-10-01 00:00:00

abstract：:Chemotherapy is a well-established therapeutic approach for several malignancies, but its clinical efficacy is often limited by its related cardiotoxicity, which leads to cardiomyopathy, possibly evolving into heart failure. To detect cardiac damage, the adopted diagnostic approach is the estimation of left ventricula...

journal_title：American journal of clinical pathology

authors： Dolci A,Dominici R,Cardinale D,Sandri MT,Panteghini M

更新日期：2008-11-01 00:00:00

abstract：:Nineteen patients with acute nonlymphocytic leukemia were found to have a pericentric inversion of chromosome 16. All were classified as having acute myelomonocytic leukemia (M4) according to French-American-British Cooperative Group (FAB) criteria. Consistent abnormalities of marrow eosinophils were present. In 15 of...

journal_title：American journal of clinical pathology

authors： Bitter MA,Le Beau MM,Larson RA,Rosner MC,Golomb HM,Rowley JD,Vardiman JW

更新日期：1984-06-01 00:00:00

abstract：:To assess the diagnostic accuracy of margin evaluation of melanocytic lesions using en face frozen sections compared with standard paraffin-embedded sections, we studied 2 sets of lesions in which en face frozen sections were used for analysis of surgical margins (13 from malignant melanomas [MMs] and 10 from nonmelan...

journal_title：American journal of clinical pathology

authors： Prieto VG,Argenyi ZB,Barnhill RL,Duray PH,Elenitsas R,From L,Guitart J,Horenstein MG,Ming ME,Piepkorn MW,Rabkin MS,Reed JA,Selim MA,Trotter MJ,Johnson MM,Shea CR

更新日期：2003-08-01 00:00:00

abstract：:Platelet function testing is important for the diagnostic evaluation of common and rare bleeding disorders. Our study goals were to promote best practices and reduce unnecessary testing variances by developing North American guidelines on platelet function testing. Guidelines were developed by consensus for expert rec...

journal_title：American journal of clinical pathology

authors： Hayward CP,Moffat KA,Raby A,Israels S,Plumhoff E,Flynn G,Zehnder JL

更新日期：2010-12-01 00:00:00

abstract：:Immunohistochemical techniques applied to fresh frozen sections of metastatic malignant melanoma tissue revealed abundant fibrinogen (or fibrin I) in perivascular areas throughout the tumor connective tissue stroma. Fibrin was readily detected in a focal distribution in the connective tissue around nodules of viable t...

journal_title：American journal of clinical pathology

authors： Wojtukiewicz MZ,Zacharski LR,Memoli VA,Kisiel W,Kudryk BJ,Rousseau SM,Stump DC

更新日期：1990-04-01 00:00:00

abstract：Objectives:The aims were to evaluate breast cancer (BC) tumor-infiltrating lymphocytes (TILs) interobserver variability, heterogeneity, and the fidelity of scoring TILs in core needle biopsy (CNB). Methods:Matching CNB and two full-face sections (FFSs) of BC cases (n = 100) were independently reviewed by two pathologi...

journal_title：American journal of clinical pathology

authors： Khoury T,Peng X,Yan L,Wang D,Nagrale V

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVES:This study examines whether the assumptions that pathologists understand the medical malpractice negligence rule and have a clear single standard of care are reasonable. METHODS:Two hundred eighty-one Texas academic pathologists and trainees were presented 10 actual pathology malpractice cases from publicly...

journal_title：American journal of clinical pathology

authors： Allen TC,Stafford M,Liang BA

更新日期：2014-04-01 00:00:00

abstract：:This review summarizes our experience using blinded review as a method to measure quality in surgical pathology. It details the specifics about how the review is performed, the weaknesses in the method, and then summarizes our results so far. These results suggest that error rates correlate with the individual patholo...

journal_title：American journal of clinical pathology

authors： Renshaw AA,Gould EW

更新日期：2007-01-01 00:00:00

abstract：:Laboratory Branch Complement Fixation and FIAX (fluorescence immunoassay) were compared for the detection of antibodies to herpes simplex virus and cytomegalovirus in human sera. Of 68 sera with no antibodies to herpes simplex virus by complement fixation, one specimen was positive by FIAX (specificity, 98.6%). Of 75 ...

journal_title：American journal of clinical pathology

authors： Segar JE,Smith TF,Ilstrup DM

更新日期：1981-03-01 00:00:00

abstract：:The "floral" variant of follicle center lymphoma (FCL) may be confused with progressive transformation of germinal centers or lymphocyte predominance Hodgkin lymphoma. Immunohistochemistry and gene rearrangement studies are usually sufficient to differentiate among these entities. We present 11 cases of floral FCL tha...

journal_title：American journal of clinical pathology

authors： Tiesinga JJ,Wu CD,Inghirami G

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVES:Bone marrows (BMs) with incidentally identified, small monotypic B-cell populations (MBPs) were evaluated. METHODS:BM aspirates with MBPs representing 5% or less of total events by flow cytometry, less than 5.0 × 10(9)/L B cells in blood, and no history of lymphoma or MBP with a different phenotype from pri...

journal_title：American journal of clinical pathology

authors： Nelson BP,Abdul-Nabi A,Goolsby C,Winter J,Peterson L

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:To differentiate the leprosy agents Mycobacterium leprae and Mycobacterium lepromatosis and correlate them with geographic distribution and clinicopathologic features. METHODS:Species-specific polymerase chain reactions were used to detect each bacillus in archived skin biopsy specimens from patients with l...

journal_title：American journal of clinical pathology

authors： Han XY,Aung FM,Choon SE,Werner B

更新日期：2014-10-01 00:00:00

abstract：:Using Venn diagrams derived from set theory, a mathematic model is presented that allows triple-label immunophenotypic analysis of cells based upon double-label measurements. Practical applications of this method are illustrated and discussed. Using this model, triple-label data concerning Leu-8 and Leu-9 (CD7) antige...

journal_title：American journal of clinical pathology

authors： Wood GS

更新日期：1989-07-01 00:00:00

abstract：:The expression of HLA class I antigens in testicular germ cell tumors (TGCTs) was studied by the immunoperoxidase technique. In the normal testicle, the interstitial cells of Leydig as well as most of the germ cells were significantly stained. In typical seminoma, 75% of the tumor cells in stage I and 30% in stage II ...

journal_title：American journal of clinical pathology

authors： Klein B,Klein T,Konichezky M,Nyska A,Livini E,Levine I,Zamir R,Kooperman O,Lurie H

更新日期：1990-02-01 00:00:00

abstract：:Mucocele-like lesion (MLL) is a rare mucinous lesion of the breast with highly variable upgrade rates to atypia or malignancy on excision. This spectrum of data has led to differing opinions on the need for surgical excision. We evaluated 50 core biopsy specimens diagnosed as having MLLs and correlated the findings wi...

journal_title：American journal of clinical pathology

authors： Sutton B,Davion S,Feldman M,Siziopikou K,Mendelson E,Sullivan M

更新日期：2012-12-01 00:00:00

abstract：:To study the distribution of lactate dehydrogenase (LDH-1) (H4) in normal, ischemic, and necrotic myocardium using the peroxidase-antiperoxidase technic, the authors studied formalin-fixed paraffin-embedded sections of human (n = 11) and canine (n = 28) myocardium. All normal control myocardium showed positive immunos...

journal_title：American journal of clinical pathology

authors： Herscher LL,Siegel RJ,Said JW,Edwalds GM,Moran MM,Fishbein MC

更新日期：1984-02-01 00:00:00

abstract：:"Chondroid chordoma" is a controversial and confusing entity that was originally described by Heffelfinger and colleagues as a biphasic malignant neoplasm possessing elements of both chordoma and cartilaginous tissue. Because the premise for this distinction was based strictly on histomorphologic criteria, the light m...

journal_title：American journal of clinical pathology

authors： Jeffrey PB,Biava CG,Davis RL

更新日期：1995-03-01 00:00:00

abstract：:Platelet-derived growth factors (PDGFs) exert their biologic function by binding to 3 different tyrosine kinase receptor isoforms. Especially the PDGF-alpha alpha receptor binds PDGF proteins with high specificity, which results in growth stimulation. The expression of the receptor and its ligand was studied in human ...

journal_title：American journal of clinical pathology

authors： Sulzbacher I,Birner P,Träxler M,Marberger M,Haitel A

更新日期：2003-07-01 00:00:00

abstract：:The diagnostic value of glypican 3 (GPC3) immunostaining on needle biopsy specimens has not been well assessed. In this study, 120 liver needle biopsy specimens, including 46 from cirrhotic livers and 74 hepatocellular carcinomas (HCCs), were immunohistochemically examined for expression of GPC3. The results showed st...

journal_title：American journal of clinical pathology

authors： Anatelli F,Chuang ST,Yang XJ,Wang HL

更新日期：2008-08-01 00:00:00

abstract：Objectives:To evaluate the prevalence of potentially unnecessary repeat testing (PURT) and the associated economic burden for an inpatient population at a large academic medical facility. Methods:We evaluated all inpatient test orders during 2016 for PURT by comparing the intertest times to published recommendations. ...

journal_title：American journal of clinical pathology

authors： Hueth KD,Jackson BR,Schmidt RL

更新日期：2018-05-31 00:00:00