Distribution of LDH-1 in normal, ischemic, and necrotic myocardium. An immunoperoxidase study.

abstract：OBJECTIVES:To evaluate the predictive value of growth patterns in patients undergoing sorafenib treatment for metastatic clear cell renal cell carcinomas (CCRCCs). METHODS:Forty-eight patients were analyzed, each of whom underwent nephrectomy and received sorafenib treatment for metastatic CCRCC. Progression-free surv...

journal_title：American journal of clinical pathology

authors： Araki H,Tsuzuki T,Kimura T,Tanaka K,Yamada S,Sassa N,Yoshino Y,Hattori R,Gotoh M

更新日期：2015-04-01 00:00:00

abstract：:The May-Hegglin anomaly is one of the rare forms of heriditary thrombocytopenia. Since fewer than 100 cases of May-Hegglin anomaly have been described to date, major controversies regarding the adequacy of hemostasis in vivo and abnormalities of platelet function in vitro continue to prevail. This report describes the...

journal_title：American journal of clinical pathology

authors： Hamilton RW,Shaikh BS,Ottie JN,Storch AE,Saleem A,White JG

更新日期：1980-11-01 00:00:00

abstract：:Using microscopic screening criteria employed in the study of sputum in acute bacterial pneumonia, the authors evaluated 644 sputum samples from 347 patients submitted for mycobacterial bacterial culture. After microscopic examination, these specimens were processed using standard mycobacterial laboratory technics. Sa...

journal_title：American journal of clinical pathology

authors： Isaac-Renton JL,Puselja BB,Allen EA,Grzybowski S,Black WA

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVES:Bone marrows (BMs) with incidentally identified, small monotypic B-cell populations (MBPs) were evaluated. METHODS:BM aspirates with MBPs representing 5% or less of total events by flow cytometry, less than 5.0 × 10(9)/L B cells in blood, and no history of lymphoma or MBP with a different phenotype from pri...

journal_title：American journal of clinical pathology

authors： Nelson BP,Abdul-Nabi A,Goolsby C,Winter J,Peterson L

更新日期：2014-05-01 00:00:00

abstract：:Twenty cases of inflammatory myofibroblastic tumor (IMT) were studied; 19 involved the lung and 1 the esophagus only. The patients' ages ranged from 3 to 72 years. There were 9 males and 11 females. Involvement of a bronchus was seen in one case and of mediastinal structures in four. Chest pain and dyspnea were common...

journal_title：American journal of clinical pathology

authors： Pettinato G,Manivel JC,De Rosa N,Dehner LP

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVES:Luminex-based single-antigen bead human leukocyte antigen (HLA) antibody testing is widely used to define HLA antibodies for transplant compatibility. False-negative results can occur with complement-mediated prozone inhibition. This study assessed the effect of EDTA on the assay background reactivity and fl...

journal_title：American journal of clinical pathology

authors： Anani WQ,Zeevi A,Lunz JG

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:MDM2 gene amplification is associated with well-differentiated (WDL) and dedifferentiated liposarcomas (DDL). Using fluorescent in situ hybridization (FISH), we sought to characterize various patterns of MDM2 amplification among the morphologic spectrum of liposarcoma. METHODS:Forty-six cases of liposarcoma...

journal_title：American journal of clinical pathology

authors： Ware PL,Snow AN,Gvalani M,Pettenati MJ,Qasem SA

更新日期：2014-03-01 00:00:00

abstract：:We describe the development and testing of a novel pre-sign-out quality assurance tool for case diagnoses that allows for the random review of a percentage of cases by a second pathologist before case verification and release of the final report. The tool incorporates the ability to record and report levels of diagnos...

journal_title：American journal of clinical pathology

authors： Owens SR,Dhir R,Yousem SA,Kelly SM,Piccoli A,Wiehagen L,Lassige K,Parwani AV

更新日期：2010-06-01 00:00:00

abstract：:Immunophenotypic analysis is useful in distinguishing reactive from neoplastic lymphoproliferations, particularly when tissue is limited or histologic findings are equivocal. Surface membrane immunoglobulin (SmIg) light chain restriction in B cells is especially helpful in documenting clonality, and the loss of SmIg b...

journal_title：American journal of clinical pathology

authors： Zhao XF,Cherian S,Sargent R,Seethala R,Bonner H,Greenberg B,Bagg A

更新日期：2005-07-01 00:00:00

abstract：:A teenage male, with Goodpasture's syndrome and serum antiglomerular basement membrane (anti-GBM) antibodies, had a focal proliferative glomerulonephritis with crescents. Immunofluorescence microscopy of his glomeruli using anti-IgG antibodies demonstrated both intense linear GBM staining, and granular subepithelial s...

journal_title：American journal of clinical pathology

authors： Jennette JC,Lamanna RW,Burnette JP,Wilkman AS,Iskander SS

更新日期：1982-09-01 00:00:00

abstract：:Hydatidiform moles can be subclassified based on their ploidy. In general, complete moles are diploid, and partial moles are triploid. The standard method for the determination of DNA content is flow cytometric analysis. In this study, the authors investigated whether static cytometric analysis with the CAS 200 Image ...

journal_title：American journal of clinical pathology

authors： Barclay ID,Dabbagh L,Babiak J,Poppema S

更新日期：1993-10-01 00:00:00

abstract：:The use of direct thrombin inhibitors (DTIs) for prophylactic or therapeutic anticoagulation is increasing because of the predictable bioavailability and short half-life of these DTIs. However, in certain situations, indication of the concentration is warranted. We investigated the effects of 3 DTIs (lepirudin, argatr...

journal_title：American journal of clinical pathology

authors： Curvers J,van de Kerkhof D,Stroobants AK,van den Dool EJ,Scharnhorst V

更新日期：2012-10-01 00:00:00

abstract：:The performance characteristics of the XE-2100 (Sysmex, Kobe, Japan) automated immature granulocyte (IG) count were studied. The automated IG count was compared with the manual morphology count and with a proposed reference flow cytometric count. The comparison data were analyzed by both least-squares and Passing-Babl...

journal_title：American journal of clinical pathology

authors： Fernandes B,Hamaguchi Y

更新日期：2007-09-01 00:00:00

abstract：:Noncardiogenic pulmonary edema caused by transfusion has been observed for almost 60 years. Today, we know this entity as transfusion-related acute lung injury (TRALI). TRALI is an uncommon but potentially fatal adverse reaction to transfusion of plasma-containing blood components. It is typified by dyspnea, cough, hy...

journal_title：American journal of clinical pathology

authors： Cherry T,Steciuk M,Reddy VV,Marques MB

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVES:BCOR-CCNB3 sarcoma (BCS) is an undifferentiated tumor that has some clinical and morphologic similarity to classic Ewing sarcoma, but it is characterized by a distinct BCOR-CCNB3 gene fusion. There are no reports describing its cytomorphologic findings. METHODS:We describe cytologic findings of five molecul...

journal_title：American journal of clinical pathology

authors： Gajdzis P,Laé M,Pierron G,Brisse HJ,Orbach D,Fréneaux P,Laurence V,Klijanienko J

更新日期：2020-02-08 00:00:00

abstract：:Three activated partial thromboplastin time (APTT) reagent test systems, General Diagnostics Automated APTT, American Dade Actin FS, and Pacific Hemostasis (Thromboscreen KAPTT) reagent, containing different activators for the APTT assay, were evaluated for their precision and sensitivity to factor deficiencies in the...

journal_title：American journal of clinical pathology

authors： Turi DC,Peerschke EI

更新日期：1986-01-01 00:00:00

abstract：:In diagnostic pathology, decision-making skills are used to match the facts of a particular case to a diagnostic category. Ideally the diagnosis is established with "beyond a reasonable doubt" certainty, but substantial uncertainty orfrank diagnostic error can afflict the diagnostic process for a variety of reasons. M...

journal_title：American journal of clinical pathology

authors： Foucar E

更新日期：2001-12-01 00:00:00

abstract：:The authors investigated the blast cells obtained from two patients with acute myelofibrosis with the use of recently developed immunochemical and ultrastructural markers. They intended to examine the expression of megakaryoblastic, erythroblastic, myeloblastic, and monoblastic properties in these cells. Respectively,...

journal_title：American journal of clinical pathology

authors： Schreeder MT,Prchal JT,Parmley RT,Carroll AJ,Gewirtz AM,Hoffman R

更新日期：1985-01-01 00:00:00

abstract：:The ability to inhibit the release reaction was found to correlate well with the ability to inhibit aggregation in washed human platelets exposed to antilymphocyte serum (ALS). However, the primary mechanism that contributes to ALS-induced aggregation in unwashed platelets appeared to be different from that found in w...

journal_title：American journal of clinical pathology

authors： Wang TY,Hussey CV,Hause LL,Fobian JE

更新日期：1976-05-01 00:00:00

abstract：:The use of rapid, simple tests to detect antibodies to human immunodeficiency virus (HIV) in urine could be valuable for several testing situations, such as in private offices, for epidemiologic surveys, and in developing countries. The authors evaluated the performance of the SUDS HIV type 1 test to detect antibody t...

journal_title：American journal of clinical pathology

authors： Constantine NT,Zhang X,Li L,Bansal J,Hyams KC,Smialek JE

更新日期：1994-02-01 00:00:00

abstract：:We performed a retrospective clinicopathologic study on sequential biopsy specimens from 90 patients with Philadelphia chromosome-positive chronic myelogenous leukemia to study therapy-specific effects of busulfan (28 patients), hydroxyurea (32 patients), and interferon-alfa (IFN-alfa; 30 patients). Bone marrow specim...

journal_title：American journal of clinical pathology

authors： Thiele J,Kvasnicka HM,Schmitt-Graeff A,Bundschuh S,Biermann T,Roessler G,Wasmus M,Diehl V,Zankovich R,Schaefer HE

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVES:We postulated that lymph node (LN) harvest and LN size are influenced by immunologic effects. METHODS:To investigate this hypothesis, we performed a retrospective analysis of 170 node-negative colon cancer cases to evaluate the density of intratumoral T lymphocytes (ITLs). CD3- and CD8-positive T cells were...

journal_title：American journal of clinical pathology

authors： Märkl B,Wieberneit J,Kretsinger H,Mayr P,Anthuber M,Arnholdt HM,Schenkirsch G

更新日期：2016-06-01 00:00:00

abstract：:This is apparently the second report of a case of human meningoencephalitis caused by the nematode Micronema deletrix. The patient had severe granulomatous meningoencephalitis with numerous foci of hemorrhage and encephalomalacia. Numerous adult female and larval M. deletrix were in the brain. The organisms probably i...

journal_title：American journal of clinical pathology

authors： Shadduck JA,Ubelaker J,Telford VQ

更新日期：1979-10-01 00:00:00

abstract：:Tissue repositories maintained by pathology departments represent an abundant resource of clinically annotated human specimens. The storage expenses associated with pathology archives are known to administrators of most pathology departments. However, such basic repository characteristics as the quality of stored mate...

journal_title：American journal of clinical pathology

authors： Smith MA,Barnes EL,Chiosea SI

更新日期：2011-05-01 00:00:00

abstract：Objectives:According to current guidelines, either immunohistochemistry (IHC) or in situ hybridization (ISH) can be used to determine human epidermal growth factor receptor 2 (Her2/neu) status in breast carcinoma. While the guidelines explicitly delineate result interpretation, there is no consensus on the most appropr...

journal_title：American journal of clinical pathology

authors： Solomon JP,Dell'Aquila M,Fadare O,Hasteh F

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVES:Mucinous cystic neoplasm of the liver is characterized by neoplastic mucinous and/or biliary epithelium surrounded by ovarian-type stroma. Immunohistochemical studies have shown that the ovarian-type stroma expresses estrogen receptor, suggesting potential hormonal responsiveness. The molecular biology of mu...

journal_title：American journal of clinical pathology

authors： Van Treeck BJ,Lotfalla M,Czeczok TW,Mounajjed T,Moreira RK,Allende DS,Reid MD,Naini BV,Westerhoff M,Adsay NV,Kerr SE,Rizvi SH,Smoot RL,Liu Y,Davila J,Graham RP

更新日期：2020-11-04 00:00:00

abstract：:This article deals with and formalizes 2 notions common to the practice of pathology. The first is that the number of lymph nodes found positive for metastasis relates directly to the total number of lymph nodes examined. The second is that for any patient, there is a chance that the absence of lymph node metastases i...

journal_title：American journal of clinical pathology

authors： Vollmer RT

更新日期：2005-05-01 00:00:00

abstract：:Our objective was to assess the loss of E-cadherin (EC) as a diagnostic marker or a predictor of prognosis. We stained 276 breast carcinomas with monoclonal antibodies to EC (invasive lobular carcinomas [ILC] and variants, 59; invasive ductal carcinoma and ductal special types [IDC], 204; tubulolobular carcinoma [TLC]...

journal_title：American journal of clinical pathology

authors： Qureshi HS,Linden MD,Divine G,Raju UB

更新日期：2006-03-01 00:00:00

abstract：:Pleomorphic adenoma (or benign mixed tumor) of the breast is a rare benign neoplasm that might be misinterpreted both clinically and pathologically as a malignant tumor. The authors present an additional case of this unusual lesion studied by immunohistochemistry, electron microscopy, and flow cytometry. A 77-year-old...

journal_title：American journal of clinical pathology

authors： Ballance WA,Ro JY,el-Naggar AK,Grignon DJ,Ayala AG,Romsdahl MG

更新日期：1990-06-01 00:00:00

abstract：:An assessment of the infrequently performed protein-bound iodine determinations (PBI) and thyroxine (T4) determinations by column chromatography is presented after analysis of data contributed by participants in the 1976 College of American Pathologists Chemistry Survey Programs. The two technics yield comparable mean...

journal_title：American journal of clinical pathology

authors： Thiessen MM,Batsakis JG,Neuhoff J,Thomas BP

更新日期：1978-09-01 00:00:00