Abstract：
:Noncardiogenic pulmonary edema caused by transfusion has been observed for almost 60 years. Today, we know this entity as transfusion-related acute lung injury (TRALI). TRALI is an uncommon but potentially fatal adverse reaction to transfusion of plasma-containing blood components. It is typified by dyspnea, cough, hypoxemia, and pulmonary edema within 6 hours of transfusion. Most commonly, it is caused by donor HLA antibodies that react with recipient antigens. It may also be caused by biologically active compounds accumulated during storage of blood products, which are capable of priming neutrophils. Without a "gold standard," the diagnosis of TRALI relies on a high index of suspicion and on excluding other types of transfusion reactions. Although current definitions of TRALI depend on symptoms, laboratory parameters can aid in the diagnosis and frequently identify the causative donor unit. As our understanding of TRALI deepens, risk reduction or prevention may become possible.
journal_name
Am J Clin Patholjournal_title
American journal of clinical pathologyauthors
Cherry T,Steciuk M,Reddy VV,Marques MBdoi
10.1309/D3F7BXH466AE3G0Psubject
Has Abstractpub_date
2008-02-01 00:00:00pages
287-97issue
2eissn
0002-9173issn
1943-7722pii
8750T18122520713journal_volume
129pub_type
杂志文章,评审abstract：OBJECTIVES:Pool testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) preserves testing resources at the risk of missing specimens through specimen dilution. METHODS:To determine whether SARS-CoV-2 specimens would be missed after 10:1 pooling, we identified 10 specimens with midrange (ie, 25-34 cycl...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
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更新日期：2021-01-05 00:00:00
abstract：:The reliability of "standard" plasmas used by clinical laboratories to assay factor VIII concentrations of patients' plasmas was studied by assessing the credibility of their reference values. Two of three commercial reference plasmas were considered to be unreliable. The third commercial reference plasma appeared to ...
journal_title：American journal of clinical pathology
pub_type： 杂志文章
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更新日期：1981-02-01 00:00:00
abstract：:HMB45 is a melanoma-specific monoclonal antibody that has found widespread use in diagnostic pathology. Recent reports, however, have suggested that this antibody may cross-react with a small number of carcinomas and other epithelial cells. The authors tested the hypothesis that these latter reports represent examples...
journal_title：American journal of clinical pathology
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更新日期：1991-04-01 00:00:00
abstract：:Immunoperoxidase strains for prostate-specific antigen (PSA), prostatic acid phosphatase (PAcP), epithelial membrane antigen (EMA), and cytokeratins (MAK 6 and CK-KES) were performed on 1 case of squamous cell carcinoma of the prostate and on 13 cases of squamous metaplasia of prostatic epithelium in an effort to demo...
journal_title：American journal of clinical pathology
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更新日期：1988-11-01 00:00:00
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更新日期：2019-10-07 00:00:00
abstract：:Human papillomavirus (HPV) testing is more sensitive for the detection of cervical precancer and cancer than cervical cytology. The increased sensitivity of HPV testing and cytology combined ("cotesting") compared to cytology alone permitted professional societies to recommend 3-year screening intervals among the cote...
journal_title：American journal of clinical pathology
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更新日期：2010-08-01 00:00:00
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journal_title：American journal of clinical pathology
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更新日期：1982-06-01 00:00:00
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journal_title：American journal of clinical pathology
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doi：10.1309/AJCP2QZRH4ZNPRDD
更新日期：2014-09-01 00:00:00
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journal_title：American journal of clinical pathology
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更新日期：1990-10-01 00:00:00
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journal_title：American journal of clinical pathology
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更新日期：1988-08-01 00:00:00
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更新日期：1984-05-01 00:00:00
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journal_title：American journal of clinical pathology
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doi：10.1309/PEF8-GL6F-YWMC-AG56
更新日期：2002-05-01 00:00:00
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journal_title：American journal of clinical pathology
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更新日期：2020-06-08 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章
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更新日期：2019-03-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/73.1.41
更新日期：1980-01-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1309/EALE-G7LD-6W71-67PX
更新日期：2003-11-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章,评审
doi：10.1309/RAPQ3NXG3MV9AL94
更新日期：2007-12-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/82.3.311
更新日期：1984-09-01 00:00:00
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journal_title：American journal of clinical pathology
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更新日期：1981-08-01 00:00:00
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journal_title：American journal of clinical pathology
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更新日期：1989-06-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章,评审
doi：
更新日期：1994-10-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：1988-03-01 00:00:00
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更新日期：1987-02-01 00:00:00
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更新日期：1976-08-01 00:00:00
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journal_title：American journal of clinical pathology
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更新日期：1990-02-01 00:00:00
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journal_title：American journal of clinical pathology
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doi：10.1093/ajcp/72.5.882
更新日期：1979-11-01 00:00:00
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journal_title：American journal of clinical pathology
pub_type： 杂志文章
doi：10.1093/ajcp/90.6.707
更新日期：1988-12-01 00:00:00
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更新日期：2014-04-01 00:00:00
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更新日期：2013-05-01 00:00:00
abstract：:One hundred eighty-three patients with endometrial carcinoma had both immunohistochemical and biochemical analysis of estrogen receptor (ER) and progesterone receptor (PR) content of the tumor. Biochemical analysis was done on a homogenate of uterine curettings; immunohistochemical stainings were done on formalin-fixe...
journal_title：American journal of clinical pathology
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doi：10.1093/ajcp/94.3.255
更新日期：1990-09-01 00:00:00
