Restrictive Transfusion Strategy and Clinical Decision Support Practices for Reducing RBC Transfusion Overuse.

Abstract:

OBJECTIVES:Assess support for the effectiveness of two separate practices, restrictive transfusion strategy and computerized physician order entry/clinical decision support (CPOE/CDS) tools, in decreasing RBC transfusions in adult surgical and nonsurgical patients. METHODS:Following the Centers for Disease Control and Prevention Laboratory Medicine Best Practice (LMBP) Systematic Review (A-6) method, studies were assessed for quality and evidence of effectiveness in reducing the percentage of patients transfused and/or units of blood transfused. RESULTS:Twenty-five studies on restrictive transfusion practice and seven studies on CPOE/CDS practice met LMBP inclusion criteria. The overall strength of the body of evidence of effectiveness for restrictive transfusion strategy and CPOE/CDS was rated as high. CONCLUSIONS:Based on these procedures, adherence to an institutional restrictive transfusion strategy and use of CPOE/CDS tools for hemoglobin alerts or reminders of the institution's restrictive transfusion policies are effective in reducing RBC transfusion overuse.

journal_name

Am J Clin Pathol

authors

Derzon JH,Clarke N,Alford A,Gross I,Shander A,Thurer R

doi

10.1093/ajcp/aqz070

subject

Has Abstract

pub_date

2019-10-07 00:00:00

pages

544-557

issue

5

eissn

0002-9173

issn

1943-7722

pii

5532293

journal_volume

152

pub_type

杂志文章
  • A field evaluation of the Coulter STKS.

    abstract::The performance of the Coulter STKS (Coulter, Hialeah, FL) was evaluated in a busy computerized teaching hospital laboratory. The STKS was compared with a Coulter S Plus IV and manually performed 400 white blood-cell differentials. The measured blood-count parameters (i.e., white blood cells [WBCs], red blood cells [R...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/95.2.207

    authors: Warner BA,Reardon DM

    更新日期:1991-02-01 00:00:00

  • Do we now know what inappropriate laboratory utilization is? An expanded systematic review of laboratory clinical audits.

    abstract:OBJECTIVES:Many nonpathologists and some pathologists consider utilization review essential to laboratory quality improvement, but (1) confusion surrounding the definition of "appropriate" laboratory utilization, (2) the reliance on manual chart review, and (3) a lack of leadership have contributed to its unstandardize...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:10.1309/AJCPX1HIEM4KLGNU

    authors: Hauser RG,Shirts BH

    更新日期:2014-06-01 00:00:00

  • Well-differentiated (tubular) carcinoma of the breast. A clinicopathologic study of 145 pure and mixed cases.

    abstract::In this study, 145 well-differentiated (tubular) carcinomas were divided into two groups: 90 pure tubular carcinomas and 55 which were mixtures in that they contained a component of infiltrating duct carcinoma occupying less than half the tumor. Axillary lymph node metastases developed in 29% of women in the mixed gro...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/78.1.1

    authors: Deos PH,Norris HJ

    更新日期:1982-07-01 00:00:00

  • Influence of blood collection systems on the prothrombin time and international sensitivity index determined with human and rabbit thromboplastin reagents.

    abstract::Three brands of blood collection tubes were studied for their influence on the prothrombin time (PT) and international sensitivity index (ISI) for 5 commercial thromboplastin reagents. With all reagents, PTs were shorter in Vacutainer (Becton Dickinson Vacutainer Systems, Plymouth, England) samples than in S-Monovette...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/NW194EAMD4WMEHJD

    authors: van den Besselaar AM,Hoekstra MM,Witteveen E,Didden JH,van der Meer FJ

    更新日期:2007-05-01 00:00:00

  • Acute Myeloid Leukemia With Myelodysplasia-Related Changes.

    abstract:OBJECTIVES:Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) is a heterogeneous disorder defined by morphologic, genetic, or clinical features. Genetic abnormalities associated with AML-MRC are often associated with adverse prognostic features, and many cases are preceded by a myelodysplastic syndrom...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:10.1309/AJCP58RSMFRHLHHH

    authors: Vardiman J,Reichard K

    更新日期:2015-07-01 00:00:00

  • Telangiectatic oncocytoma: a previously undescribed variant of renal oncocytoma.

    abstract:OBJECTIVES:To identify, describe, and investigate the clinical, radiologic, and pathologic features of 8 cases of telangiectatic oncocytoma. METHODS:Fifty-three consecutive renal oncocytomas were reviewed for the telangiectatic pathologic features that were subsequently correlated with the demographic, clinical, and r...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCP9HDXYB2WYYJX

    authors: Xiao GQ,Ko HB,Unger P

    更新日期:2013-07-01 00:00:00

  • Diagnosing platelet delta-storage pool disease in children by flow cytometry.

    abstract::Bleeding problems are symptomatic of platelet delta-storage pool diseases (SPDs) such as Hermansky-Pudlak syndrome. Although at present no cure is available for delta-SPD, early diagnosis is of great importance for prophylactic and supportive treatment. This study tested the usefulness of a flow cytometric assay for p...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/3KRYCPNAPDTVFWGY

    authors: Maurer-Spurej E,Pittendreigh C,Wu JK

    更新日期:2007-04-01 00:00:00

  • Immunohistochemical vs molecular biology methods. Complementary techniques for effective screening of p53 alterations in head and neck cancer.

    abstract::The purpose of this study was to correlate p53 gene alterations and their expression in 85 head and neck squamous cell carcinomas. Genomic p53 was amplified with the polymerase chain reaction (PCR) from formalin-fixed, paraffin-embedded tissues. Exons 5 through 8 were screened for mutations by means of non-isotopic si...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/107.1.7

    authors: Calzolari A,Chiarelli I,Bianchi S,Messerini L,Gallo O,Porfirio B,Mattiuz PL

    更新日期:1997-01-01 00:00:00

  • Impersonal medical care. Role of the pathologist in its evolution.

    abstract::An evaluation of the change in the former close relationship between the patient and his physician, and the contribution of the pathologist to its development, is presented. The effect of these changes on the interest in and care of the patient by all in the hospital in this changing medical scene is decried; the pati...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/64.1.136

    authors: Angrist AA

    更新日期:1975-07-01 00:00:00

  • Assessment of platelet function on whole blood by multiple electrode aggregometry in high-risk patients with coronary artery disease receiving antiplatelet therapy.

    abstract::This study sought to compare Multiplate impedance platelet aggregometry (IPA) with light transmission aggregometry (LTA) and the PFA-100 for determining the prevalence of residual platelet reactivity (RPR) by the Multiplate IPA in 297 patients with acute coronary syndrome receiving dual antiplatelet therapy. Aggregati...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCPTE3K1SGAPOIZ

    authors: Paniccia R,Antonucci E,Maggini N,Romano E,Gori AM,Marcucci R,Prisco D,Abbate R

    更新日期:2009-06-01 00:00:00

  • Racial differences in vitamin B12 levels in the United States.

    abstract::Studies from Africa have demonstrated that black people have higher vitamin B12 (cobalamin) levels than do white people. The authors compared healthy white people, black people, and Latin-Americans in the United States. Their study is also the largest in which the effect of race and sex on the cobalamin levels has bee...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/88.1.95

    authors: Saxena S,Carmel R

    更新日期:1987-07-01 00:00:00

  • Clinical and pathologic findings of the liver in the acquired immune deficiency syndrome (AIDS).

    abstract::Clinical data and histologic sections of the liver, including immunohistochemical studies for hepatitis B surface and core antigens, were reviewed in 42 autopsy cases of the acquired immune deficiency syndrome (AIDS). Hepatomegaly, elevation of serum transaminases, and mild elevation of alkaline phosphatase were commo...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/83.5.582

    authors: Glasgow BJ,Anders K,Layfield LJ,Steinsapir KD,Gitnick GL,Lewin KJ

    更新日期:1985-05-01 00:00:00

  • Expression of the Leu-8 antigen by B-cell lymphomas.

    abstract::The Leu-8 antigen is found on the surface of many hematologic cells, including many T- and B-lymphocytes. With the use of a frozen-section immunoperoxidase technic, 152 B-cell non-Hodgkin's lymphomas were examined for Leu-8 expression. Of these lymphomas, 53% expressed Leu-8. Subclassification of the lymphomas with th...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/88.4.486

    authors: Michie SA,Garcia CF,Strickler JG,Dailey MO,Rouse RV,Warnke RA

    更新日期:1987-10-01 00:00:00

  • Some statistical implications of rounding in the College of American Pathologists Survey.

    abstract::Quantitative measurements of constituent concentrations of Survey specimens are generally recorded to the nearest integer or to the nearest tenth. Questions have arisen as to whether this degree of rounding of measurements is appropriate when available laboratory equipment can determine results more precisely. Statist...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:

    authors: Williams GW,Schork MA

    更新日期:1976-07-01 00:00:00

  • Antithrombin and heparin antithrombin patterns in pre-thrombosis and thrombosis.

    abstract::An antithrombin assay (AA) and an antithrombin assay modified by the addition of heparin (H-AA) were performed using sera from healthy subjects, patients predisposed to thrombosis, and patients with thromboembolic disease. Characteristic AA, and H-AA patterns were found in each group. Normal controls and four of 39 "p...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/65.3.384

    authors: Innerfield I,Stone ML,Mersheimer W,Clauss RD,Greenberg J

    更新日期:1976-03-01 00:00:00

  • Breast carcinoma kinetics. Argyrophilic nucleolar organizer region counts correlate with Ki67 scores.

    abstract::This study assessed the value of argyrophilic nucleolar organizer region (AgNOR) staining as a potential technique for the estimation of cell kinetics in conventional histology sections, in benign and malignant breast lesions. Using a silver staining technique and immunohistochemistry, the authors correlated the numbe...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/92.4.401

    authors: Dervan PA,Gilmartin LG,Loftus BM,Carney DN

    更新日期:1989-10-01 00:00:00

  • Pathogen inactivation: a new paradigm for preventing transfusion-transmitted infections.

    abstract::Remarkable improvements have been made in blood safety since the onset of the HIV epidemic. However, the current paradigm does not prevent all transfusion-transmitted infections and is reactive to new agents, thus accepting that some patients may be harmed before preventive measures are introduced. Several methods are...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:10.1309/RAPQ3NXG3MV9AL94

    authors: McCullough J

    更新日期:2007-12-01 00:00:00

  • A cost-effective algorithm for hereditary nonpolyposis colorectal cancer detection.

    abstract::Colorectal cancer with microsatellite instability (MSI) may occur sporadically or be inherited in cases of hereditary nonpolyposis colorectal cancer (HNPCC) syndrome. However, there is no consensus as to which patients must be tested and how to test MSI. In this study, MSI was tested by immunohistochemical analysis an...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/B0AF-DT52-ETMK-EJBE

    authors: Bouzourene H,Taminelli L,Chaubert P,Monnerat C,Seelentag W,Sandmeier D,Andrejevic S,Matter M,Bosman F,Benhattar J

    更新日期:2006-06-01 00:00:00

  • Papillary thyroid carcinoma with heterotopic ossification is a special subtype with extensive progression.

    abstract::An immunohistochemical study was conducted of 108 papillary carcinoma cases, including 48 cases with intratumoral heterotopic ossification (IHO). In 48 cases, papillary carcinoma with IHO was accompanied by nodular fibrosis. Cases of papillary carcinoma with IHO or nodular fibrosis showed higher incidences of lymph no...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCPQZQN50HKIAHA

    authors: Takeda M,Mikami T,Numata Y,Okamoto M,Okayasu I

    更新日期:2013-05-01 00:00:00

  • Common genomic aberrations in basaloid squamous cell carcinoma and carcinosarcoma of the esophagus detected by CGH and array CGH.

    abstract::Basaloid squamous cell carcinoma (BSCC) and carcinosarcoma of the esophagus are rare entities, making up fewer than 2% of esophageal malignancies. Comparative genomic hybridization (CGH) in 1 case of BSCC and 2 cases of carcinosarcoma and subsequent array CGH in 1 case each of BSCC and carcinosarcoma revealed common c...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCPZ1O7UUUISPNR

    authors: Schaefer IM,Enders C,Polten A,Haller F,Frölich AM,Cameron S,Schüler P,Schweiger P,Gunawan B,Beham A,Füzesi L

    更新日期:2011-04-01 00:00:00

  • Lesions indefinite for intraepithelial neoplasia and OLGA staging for gastric atrophy.

    abstract::Gastric intraepithelial neoplasia (IEN; formerly dysplasia) is an advanced precancerous lesion. Lesions indefinite for IEN mimic the IEN phenotype but lack some morphologic attributes of IEN. Indefinite for IEN lesions may arise in native foveolae (atypical foveolar hyperproliferation [aFH]) or intestinalized glands (...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCPEU41HTGXSJDQ

    authors: Fassan M,Pizzi M,Farinati F,Nitti D,Zagonel V,Genta RM,Rugge M

    更新日期:2012-05-01 00:00:00

  • Cytologic/histologic correlation for quality control in cervicovaginal cytology. Experience with 1,582 paired cases.

    abstract::For quality-control purposes, federal regulations require cytology laboratories to compare Papanicolaou smear and cervical biopsy reports, if available, and determine the cause of any discrepancies. The authors reviewed 56,497 cervicovaginal smears, of which 1,582 (2.8%) had a subsequent cervical biopsy or endocervica...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/103.1.32

    authors: Joste NE,Crum CP,Cibas ES

    更新日期:1995-01-01 00:00:00

  • Prostaglandins in histiocytosis-X. PG synthesis by histiocytosis-X cells.

    abstract::Histiocytosis-X cells were obtained at autopsy from the lungs and lymph nodes of a patient who died of the disseminated infantile form of this disease (Letterer-Siwe disease). The ability of these cells to synthesize and release prostaglandins was investigated in culture, by prelabeling the cell lipids with [14C] arac...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/75.2.243

    authors: Gonzalez-Crussi F,Hsueh W,Wiederhold MD

    更新日期:1981-02-01 00:00:00

  • Carcinomesenchymoma of the uterus.

    abstract::A unique case of intramural uterine tumor composed of malignant epithelium and benign smooth muscle, adipose tissue, and cartilage is reported. This tumor, which the authors designated "carcinomesenchymoma," apparently represents an example of a previously unreported variant of mixed müllerian tumor that is composed o...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/75.5.746

    authors: Chen KT,Vergon JM

    更新日期:1981-05-01 00:00:00

  • Evidence for hyperglycemic osmotic matrix effects on the Comprehensive Hematology Survey 1981-1982.

    abstract::Several authors have suggested that a plausible mechanism for variation in reported mean corpuscular volume (MCV) and hematocrit values for Hematology Survey Specimens may be due to the presence of hyperglycemia in the suspending matrix of the specimens, resulting in cell swelling due to an osmotic matrix effect. The ...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:

    authors: Savage RA

    更新日期:1983-10-01 00:00:00

  • The liver in celiac disease: clinical manifestations, histologic features, and response to gluten-free diet in 30 patients.

    abstract::Descriptive reports of liver histologic features in celiac disease (CD) are sparse, and the effect of a gluten-free diet (GFD) on the course of liver injury is poorly understood. We reviewed liver biopsy specimens in 30 patients with CD and performed immunostains for IgG, IgG4, IgM, and IgA. Subsequent liver biochemic...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCPDOMY5RI5TPMN

    authors: Mounajjed T,Oxentenko A,Shmidt E,Smyrk T

    更新日期:2011-07-01 00:00:00

  • The reticulocyte. An approach to definition.

    abstract::Experiences of the CAP Survey Program in reticulocyte counts and morphologic identification of reticulocytes from 1971 to 1974 are reviewed. Problems of morphologic identification are reflected in an excessive variance of reticulocyte counts. Statistical sources of variations in counting are identified. The older, ori...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:

    authors: Gilmer PR Jr,Koepke JA

    更新日期:1976-07-01 00:00:00

  • Polymeric (presumed tetrameric) lambda Bence Jones proteinemia without proteinuria in a patient with multiple myeloma.

    abstract::A 55-year-old man presented with nerve compression and examination of tissue removed by laminectomy, and bone marrow aspiration was diagnostic of multiple myeloma. Protein studies showed a total serum protein of 5.7 g/dL, with a M-component in the fast beta region. The abnormal protein reacted only with anti-lambda an...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:

    authors: Hom BL

    更新日期:1984-11-01 00:00:00

  • Immunohistochemical characterization of pulmonary blastoma.

    abstract::The immunohistochemical staining patterns of three pulmonary blastomas (PBs) were studied for markers of mesenchymal (vimentin, muscle-specific actin) and epithelial (cytokeratin, epithelial membrane antigen) differentiation to clarify their phenotypic nature and, possibly, their histogenesis. Epithelial markers were ...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/89.6.773

    authors: Berean K,Truong LD,Dudley AW Jr,Cagle PT

    更新日期:1988-06-01 00:00:00

  • Comparison of the diagnostic values of biopsies of the pleura and cytologic evaluation of pleural fluids.

    abstract::Results of a comparison of the diagnostic efficacy of percutaneous needle biopsy of the parietal pleura with that of cytologic examination of pleural fluid sediment obtained concurrently from 166 patients with benign or cancerous pleural disorders are reported. Of 44 patients with confirmatory evidence of cancer invol...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/72.1.48

    authors: Frist B,Kahan AV,Koss LG

    更新日期:1979-07-01 00:00:00