Assessment of interlaboratory variation in the immunohistochemical determination of estrogen receptor status using a breast cancer tissue microarray.

abstract：:This study assessed the value of argyrophilic nucleolar organizer region (AgNOR) staining as a potential technique for the estimation of cell kinetics in conventional histology sections, in benign and malignant breast lesions. Using a silver staining technique and immunohistochemistry, the authors correlated the numbe...

journal_title：American journal of clinical pathology

authors： Dervan PA,Gilmartin LG,Loftus BM,Carney DN

更新日期：1989-10-01 00:00:00

abstract：:The case of a 3-week-old infant with Coxsackie B3 meningoencephalitis is discussed. Hypoglycorrhachia and neutrophils in the cerebrospinal fluid characterized the first ten days of her illness. Coxsackie B3 should be added to the list of enteroviruses that can cause hypoglycorrhachia during infections of the central n...

journal_title：American journal of clinical pathology

authors： Chesney PJ,Quennec P,Clark C

更新日期：1978-12-01 00:00:00

abstract：:Sera from heparinized patients commonly display anodal slurring of both the alpha and beta lipoproteins when they are examined by high-resolution electrophoresis (HRE). In this study, the authors examined the effect of heparin and lipoprotein lipase on the electrophoretic migration of alpha and beta lipoproteins in se...

journal_title：American journal of clinical pathology

authors： Pearson JP,Keren DF

更新日期：1995-10-01 00:00:00

abstract：:Histiocytosis-X cells were obtained at autopsy from the lungs and lymph nodes of a patient who died of the disseminated infantile form of this disease (Letterer-Siwe disease). The ability of these cells to synthesize and release prostaglandins was investigated in culture, by prelabeling the cell lipids with [14C] arac...

journal_title：American journal of clinical pathology

authors： Gonzalez-Crussi F,Hsueh W,Wiederhold MD

更新日期：1981-02-01 00:00:00

abstract：:By electrophoresis, prealbumin is seen as a discrete band anodic to the albumin fraction. Cases of duplicate bands in the prealbumin region have been described previously in serum, cerebrospinal fluid, and urine, and have had an association with varied clinical entities. The authors describe a novel association of sev...

journal_title：American journal of clinical pathology

authors： Castañeda L,Ruiz P

更新日期：1994-04-01 00:00:00

abstract：:Three anti-Factor-VIII antibodies from hemophiliacs were reacted with samples of batches of Maws commerical bovine and porcine Factor VIII concentrates manufactured over a 12-year period. The apparent antibody concentrations varied widely with the different batches of concentrates. The variations are probably due to i...

journal_title：American journal of clinical pathology

authors： Edson JR,Swinehart CD

更新日期：1976-06-01 00:00:00

abstract：:Transfusion-related acute lung injury (TRALI) is the leading cause of mortality from transfusion therapy. Recipient, donor, and blood product risk factors may have important roles in the occurrence of TRALI. A case-control pilot study of 6 TRALI cases in which HLA-antibody concordance was found and 20 control subjects...

journal_title：American journal of clinical pathology

authors： Sanchez R,Bacchetti P,Toy P

更新日期：2007-07-01 00:00:00

abstract：:Two cases of giant-cell arteritis of uterus were found incidentally in association with uterine prolapse. One similar case has been reported in the literature. Microscopic examination disclosed fragmentation of the elastic laminae of the myometrial arteries with a giant-cell and mononuclear infiltrate. The relationshi...

journal_title：American journal of clinical pathology

authors： Pirozynski WJ

更新日期：1976-03-01 00:00:00

abstract：:The development of sensitive immunofluorescent technics for the detection of platelet antibodies has stimulated renewed interest in the field of platelet immunology. However, the analysis of multispecific sera containing both HLA and platelet-specific antibodies requires cumbersome absorption technics and relatively l...

journal_title：American journal of clinical pathology

authors： Boisvert A,MacPherson BR

更新日期：1983-12-01 00:00:00

abstract：:A structure resembling a sulfur granule found in histologic sections of endometrium from patients with intrauterine contraceptive devices is described. It is distinguished from a true sulfur granule on morphologic grounds and is further characterized as a foreign substance, most probably fragments of the synthetic con...

journal_title：American journal of clinical pathology

authors： O'Brien PK,Roth-Moyo LA,Davis BA

更新日期：1981-06-01 00:00:00

abstract：:The authors report the clinicopathologic features of 14 cases of amyloid goiter (AG). Eleven patients were males and three females with ages ranging from 23 to 75 years (median, 54 years). Eight patients had secondary amyloidosis and six had primary amyloidosis. Nine cases were identified at autopsy. In symptomatic pa...

journal_title：American journal of clinical pathology

authors： Hamed G,Heffess CS,Shmookler BM,Wenig BM

更新日期：1995-09-01 00:00:00

abstract：:We examined the occurrence of JAK2(V617F) and JAK2 exon 12 mutations in a clinical cohort of polycythemia vera (PV) in Taiwan. Of 22 patients with PV, 17 (77%) had the V617F mutation, and all 5 V617F-negative patients (23%) had the exon 12 mutation. We found 3 different exon 12 mutations: 3 N542-E543del, 1 F537-K539de...

journal_title：American journal of clinical pathology

authors： Yeh YM,Chen YL,Cheng HY,Su WC,Chow NH,Chen TY,Ho CL

更新日期：2010-08-01 00:00:00

abstract：:Colorectal cancer with microsatellite instability (MSI) may occur sporadically or be inherited in cases of hereditary nonpolyposis colorectal cancer (HNPCC) syndrome. However, there is no consensus as to which patients must be tested and how to test MSI. In this study, MSI was tested by immunohistochemical analysis an...

journal_title：American journal of clinical pathology

authors： Bouzourene H,Taminelli L,Chaubert P,Monnerat C,Seelentag W,Sandmeier D,Andrejevic S,Matter M,Bosman F,Benhattar J

更新日期：2006-06-01 00:00:00

abstract：:Clq precipitins were assayed in a model system by absorption nephelometry. Polyethylene glycol was used to extract immune complexes so that sufficient sensitivity with minimal interference could be achieved. Using a double beam spectrophotometer, we found that the reaction of immune complexes with Clq occurred rapidly...

journal_title：American journal of clinical pathology

authors： Levinson SS,Goldman J

更新日期：1983-04-01 00:00:00

abstract：:Whipple disease is a rare, chronic multisystem disease associated with the recently characterized organism Tropheryma whippelii. Extraintestinal manifestation involving the central nervous system, heart, and joints occasionally occurs. Involvement of the abdominal lymph nodes, especially the mesenteric and periaortic ...

journal_title：American journal of clinical pathology

authors： Alkan S,Beals TF,Schnitzer B

更新日期：2001-12-01 00:00:00

abstract：:Pseudomonas aeruginosa is a frequent and virulent pulmonary pathogen in patients with cystic fibrosis. If colonization is not prevented, P aeruginosa becomes permanently established and nearly always mutates into a mucoid strain. The alginate-containing matrix of the mucoid strain is thought to allow the formation of ...

journal_title：American journal of clinical pathology

authors： Pritt B,O'Brien L,Winn W

更新日期：2007-07-01 00:00:00

abstract：:Antiphospholipid antibodies (aPLs) have been implicated in atherogenesis. We studied 344 patients with acute coronary syndromes; approximately 40% were aPL+ in 1 or more tests and 60% aPL-. In 215 patients, coronary artery disease (CAD) was angiographically documented, with 43.7% positive for aPL vs 34.9% of patients ...

journal_title：American journal of clinical pathology

authors： Greco TP,Conti-Kelly AM,Greco T Jr,Doyle R,Matsuura E,Anthony JR,Lopez LR

更新日期：2009-10-01 00:00:00

abstract：:An aggressive visceral form of Kaposi's sarcoma (KS) has been reported in immunosuppressed populations, most notably in patients with acquired immunodeficiency syndrome (AIDS). This presentation contrasts from the indolent skin lesions on the extremities of older males and is distinct enough in the young adult America...

journal_title：American journal of clinical pathology

authors： Berman MA,Nalesnik MA,Kapadia SB,Rinaldo CR Jr,Jensen F

更新日期：1986-09-01 00:00:00

abstract：OBJECTIVES:To demonstrate the impact of genetics specialists on identifying test order errors and improving reimbursement for genetic testing. METHODS:Forty-four cases in which whole exome sequencing (WES) was performed but not reimbursed were reviewed by a genetic counselor through simulated prospective and retrospec...

journal_title：American journal of clinical pathology

authors： Conway ME,Kalejta CD,Sternen DL,Singh IR

更新日期：2020-03-09 00:00:00

abstract：:The clinical, light microscopic, and immunohistochemical features of 14 sinonasal malignant melanomas were studied to show their diverse morphologic appearance and distinction from therapeutically more amenable neoplasms that occur in this region. The tumors arose in 6 men and 8 women (median age, 70 years). Eleven pa...

journal_title：American journal of clinical pathology

authors： Franquemont DW,Mills SE

更新日期：1991-12-01 00:00:00

abstract：:A method using the RNA polymerase chain reaction technique to diagnose infection retrospectively using single-stranded RNA enteroviruses in paraffin-embedded tissue blocks is reported. This method takes advantage of extreme sequence conservation in the 5' untranslated region of the enteroviral genome and uses two roun...

journal_title：American journal of clinical pathology

authors： Redline RW,Genest DR,Tycko B

更新日期：1991-11-01 00:00:00

abstract：:The authors investigated the humoral and tissue expression of six antigens associated with medullary thyroid cancer (MTC): calcitonin (CT), calcitonin gene-related peptide (CGRP), carcinoembryonic antigen (CEA), neuron-specific enolase (NSE), somatostatin (SRIF), and thyroglobulin (TG). The antigens were studied in th...

journal_title：American journal of clinical pathology

authors： Pacini F,Basolo F,Elisei R,Fugazzola L,Cola A,Pinchera A

更新日期：1991-03-01 00:00:00

abstract：:We analyzed the diagnostic role of claudins in effusion cytology in 325 effusions, including 218 ovarian, 49 breast, 15 cervical or endometrial, 10 gastrointestinal, and 8 lung adenocarcinomas and 25 malignant mesotheliomas (MMs). Specimens were analyzed for claudin-1 and claudin-3 expression using immunohistochemical...

journal_title：American journal of clinical pathology

authors： Kleinberg L,Holth A,Fridman E,Schwartz I,Shih IeM,Davidson B

更新日期：2007-06-01 00:00:00

abstract：:Plasma biomarker analysis requires intact unbiased starting material. We analyzed the effects on plasma protein profiles of protease inhibitor cocktails and preprocessing storage. Plasma from 12 healthy subjects collected with and without protease inhibitors was prepared immediately and after 2 hours of room temperatu...

journal_title：American journal of clinical pathology

authors： Ayache S,Panelli M,Marincola FM,Stroncek DF

更新日期：2006-08-01 00:00:00

abstract：:A number of genetic abnormalities have been detected in multiple myeloma (MM) using cytogenetic techniques. The prominent abnormalities are deletions of 13q and translocations affecting the IgH locus on 14q32. The recurrence of chromosomal abnormalities in MM suggests a specific role for them concerning its pathogenes...

journal_title：American journal of clinical pathology

authors： Tchinda J,Volpert S,Kropff M,Berdel WE,Kienast J,Meinhardt F,Horst J

更新日期：2004-12-01 00:00:00

abstract：:Sera have been submitted to the authors' laboratory for syphilis testing at a dramatically increased rate since the start of the human immunodeficiency virus type 1 epidemic. Thus they were interested in evaluating a new enzyme immunoassay, the DCL Syphilis-G test kit (DCL-G, Diagnostic Chemicals Ltd., Oxford, CT) for...

journal_title：American journal of clinical pathology

authors： Nayar R,Campos JM

更新日期：1993-03-01 00:00:00

abstract：:Adenomatous polyps are common neoplastic lesions of the large intestine. The risk of carcinoma increases with polyp size. Small polyps are typically totally embedded for histologic examination, but no standard method for sampling large, grossly benign polyps has been established. We reviewed grossly noninvasive adenom...

journal_title：American journal of clinical pathology

authors： Euscher ED,Niemann TH,Lucas JG,Kurokawa AM,Frankel WL

更新日期：2001-09-01 00:00:00

abstract：:Three cases of infantile hemangioendothelioma were immunohistochemically studied with the use of antibodies against von Willebrand factor (vWF), Ulex europaeus I lectin (UEA I), vimentin, thrombomodulin (TM), and actin, as endothelial cell (EC) markers. Because of a broad variety of histologic features, the growth pat...

journal_title：American journal of clinical pathology

authors： Yasunaga C,Sueishi K,Ohgami H,Suita S,Kawanami T

更新日期：1989-06-01 00:00:00

abstract：:Terminal deoxynucleotidyl transferase (TdT) is a marker of lymphoblastic disorders. Previously, the technique for determining TdT on smears was by indirect immunofluorescence. An immunoperoxidase procedure for detecting TdT on smears is reported. Results are in a comparable range with the indirect immunofluorescent te...

journal_title：American journal of clinical pathology

authors： Stass SA,Dean L,Peiper SC,Bollum FJ

更新日期：1982-02-01 00:00:00

abstract：:We evaluated the immunohistochemical profile and specificity of CD138 reactivity in 238 specimens from hematopoietic and nonhematopoietic neoplasms. In 91 bone marrow biopsies, CD138 reactivity was observed for nonneoplastic plasma cells, neoplastic plasma cells in multiple myeloma cases (43/43), and the plasmacytic c...

journal_title：American journal of clinical pathology

authors： O'Connell FP,Pinkus JL,Pinkus GS

更新日期：2004-02-01 00:00:00