beta-Catenin is expressed aberrantly in tumors expressing shadow cells. Pilomatricoma, craniopharyngioma, and calcifying odontogenic cyst.

abstract：:Recent reports show that the sensitivity of endometrial carcinoma detection on liquid-based Papanicolaou (Pap) tests (88%) is considerably higher than that reported on conventional Pap smears (20%-30%), although few laboratories have corroborated these results. We performed a 5-year retrospective review of all liquid-...

journal_title：American journal of clinical pathology

authors： Sams SB,Currens HS,Raab SS

更新日期：2012-02-01 00:00:00

abstract：:Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae are endemic in New York City hospitals and have been associated with serious infections globally. A real-time polymerase chain reaction (RT-PCR) assay was developed to detect carbapenem resistance attributable to KPC from blood culture bottles posi...

journal_title：American journal of clinical pathology

authors： Francis RO,Wu F,Della-Latta P,Shi J,Whittier S

更新日期：2012-04-01 00:00:00

abstract：:The efficacy of a noninvasive hemoglobin monitoring device (Astrin, Sysmex, Kobe, Japan) was evaluated for healthy volunteers and for patients with hematologic disorders. At the same time, the effects of WBC counts on noninvasive monitoring were studied by clinical evaluation and in ex vivo experiments. The hemoglobin...

journal_title：American journal of clinical pathology

authors： Saigo K,Imoto S,Hashimoto M,Mito H,Moriya J,Chinzei T,Kubota Y,Numada S,Ozawa T,Kumagai S

更新日期：2004-01-01 00:00:00

abstract：:We evaluated the immunohistochemical profile and specificity of CD138 reactivity in 238 specimens from hematopoietic and nonhematopoietic neoplasms. In 91 bone marrow biopsies, CD138 reactivity was observed for nonneoplastic plasma cells, neoplastic plasma cells in multiple myeloma cases (43/43), and the plasmacytic c...

journal_title：American journal of clinical pathology

authors： O'Connell FP,Pinkus JL,Pinkus GS

更新日期：2004-02-01 00:00:00

abstract：:Serum creatine kinase (CK) was measured in 515 healthy white women and 28 obligate carriers for Duchenne muscular dystrophy. There was substantial overlap between the control and carrier populations. To analyze the impact of the degree of overlap, the predictive value of a CK result was determined by (1) using sensiti...

journal_title：American journal of clinical pathology

authors： Gruemer HD,Miller WG,Chinchilli VM,Leshner RT,Blasco PA,Hassler CR,Nance WE

更新日期：1985-11-01 00:00:00

abstract：:Free testosterone (FT) measurement by equilibrium dialysis and liquid chromatography-tandem mass spectroscopy (LCMS/MS) is the "gold standard." We hypothesized that calculated FT values could substitute for measured values; compared FT results reported by Walter Reed Army Medical Center (WRAMC), Washington, DC, with r...

journal_title：American journal of clinical pathology

authors： DeVan ML,Bankson DD,Abadie JM

更新日期：2008-03-01 00:00:00

abstract：:Analysis of the data for the 1969 to 1973 CAP Surveys of proficiency in partial thromboplastin time (PTT) determination indicates more than desirable variability in this measurement. Non-activated procedures show greater interlaboratory variability than activated methods; therefore, they may be preferable for routine ...

journal_title：American journal of clinical pathology

authors： Koepke JA

更新日期：1975-06-01 00:00:00

abstract：:This study assessed the value of argyrophilic nucleolar organizer region (AgNOR) staining as a potential technique for the estimation of cell kinetics in conventional histology sections, in benign and malignant breast lesions. Using a silver staining technique and immunohistochemistry, the authors correlated the numbe...

journal_title：American journal of clinical pathology

authors： Dervan PA,Gilmartin LG,Loftus BM,Carney DN

更新日期：1989-10-01 00:00:00

abstract：:A number of reports have highlighted discrepancies between the DuPont aca and fibrometer-based methods for quantitating plasma fibrinogen levels. Although many authors have suggested that the presence of fibrin(ogen) degradation products are in some way responsible for the discrepancies, no direct test of this hypothe...

journal_title：American journal of clinical pathology

authors： Hoffman M,Greenberg CS

更新日期：1987-10-01 00:00:00

abstract：:This study describes results of fresh-frozen immunohistochemistry applied to two typical Warthin's tumors. Polyclonal follicular center cell staining and an apparent reduction in the number of T-lymphocytes were found. These observations tend to support the concept that the lymphoid infiltrate in Warthin's tumor repre...

journal_title：American journal of clinical pathology

authors： Tubbs RR,Sheibani K,Weiss RA,Lee V,Sebek BA,Valenzuela R

更新日期：1980-12-01 00:00:00

abstract：:In the absence of clinical signs, elevated values of the cardiac isoforms of troponin T (cTnT) and I (cTnI) can be found in the serum samples of some patients with skeletal muscle myopathies; the cause is unclear. We studied the messenger RNA (mRNA) expression of cTnT and cTnI in the skeletal muscles of 24 patients wi...

journal_title：American journal of clinical pathology

authors： Messner B,Baum H,Fischer P,Quasthoff S,Neumeier D

更新日期：2000-10-01 00:00:00

abstract：:In view of their reported reciprocal effects on apoptosis, the expression of p53 and bcl-2 proteins was studied in 46 cases of Hodgkin's disease by immunocytochemical labeling. We found p53 protein in Reed-Sternberg cells and their mononuclear variants in 16 of the 46 cases (34.7%) of Hodgkin's disease, mainly in a nu...

journal_title：American journal of clinical pathology

authors： Doussis IA,Pezzella F,Lane DP,Gatter KC,Mason DY

更新日期：1993-06-01 00:00:00

abstract：:The greater precision in prothrombin time monitoring obtained using thromboplastins with low international sensitivity index (ISI) values are believed to result in improved patient care. The authors conducted a blinded prospective study of 84 random patients on low-intensity warfarin therapy who were monitored with ei...

journal_title：American journal of clinical pathology

authors： Brophy MT,Fiore LD,Lau J,Goodwin R,Lopez A,Deykin D

更新日期：1994-07-01 00:00:00

abstract：:Heterogeneous expression or amplification is a challenge to HER2 diagnostics. A guideline defines heterogeneity as the presence of between 5% and 50% cells with HER2/CEP17 ratios of more than 2.20. We audited the frequency of such cells and their clinical impact in the results from 2 pathology laboratories combined wi...

journal_title：American journal of clinical pathology

authors： Bartlett AI,Starcyznski J,Robson T,Maclellan A,Campbell FM,van de Velde CJ,Hasenburg A,Markopoulos C,Seynaeve C,Rea D,Bartlett JM

更新日期：2011-08-01 00:00:00

abstract：:The blood counts and lactic dehydrogenase values of eight patients with thrombotic thrombocytopenic purpura (TTP) were reviewed in relation to the clinical course. Three of the eight patients died. In these patients, the hemoglobin was significantly lower and the LDH higher at the time of presentation than that of the...

journal_title：American journal of clinical pathology

authors： Crowley JP,Metzger JB,L'Europa RA

更新日期：1983-11-01 00:00:00

abstract：:Complete hydatidiform moles (CHM) and partial hydatidiform moles (PHM) represent different clinicopathologic entities. To obtain prognostic and therapeutic information about both entities, it is important that pathologic classification be as accurate as possible. The distinction of molar pregnancy and an abortus with ...

journal_title：American journal of clinical pathology

authors： Ostrzega N,Phillipson J,Liu P

更新日期：1998-12-01 00:00:00

abstract：:We studied the role of ischemia-modified albumin (IMA) with standard biomarkers (myoglobin, creatine kinase-MB [CK-MB], troponin I [TnI]) in assessment of 200 patients with suspected myocardial ischemia admitted to the emergency department. Every case was reviewed by a cardiologist. A clinical diagnosis of ischemia wa...

journal_title：American journal of clinical pathology

authors： Anwaruddin S,Januzzi JL Jr,Baggish AL,Lewandrowski EL,Lewandrowski KB

更新日期：2005-01-01 00:00:00

abstract：:Increasingly, all automated blood counts are not accompanied by a microscopic white blood cell differential. A popular strategy is to obtain a manual differential if any part of the automated blood count and differential is outside specified limits (the "diff-if" strategy). The authors compared two sets of criteria to...

journal_title：American journal of clinical pathology

authors： McClure S,Bates JE,Harrison R,Gilmer PR,Bessman JD

更新日期：1988-08-01 00:00:00

abstract：:This investigation was designed to improve reference information and to evaluate the influences of sample distribution and age on the derived reference intervals. Specimens from 127 men were collected after a 12- to 14-hour fast and analyzed by 60 different laboratory procedures. Differences in the reference intervals...

journal_title：American journal of clinical pathology

authors： Ash KO,Clark SJ,Sandberg LB,Hunter E,Woodward SC

更新日期：1983-05-01 00:00:00

abstract：:The recent clinical and commercial success of anticancer antibodies such as rituximab and trastuzumab has created great interest in antibody-based therapeutics for hematopoietic malignant neoplasms and solid tumors. Given the likelihood of lower toxic effects of antibodies that target tumor cells and have limited impa...

journal_title：American journal of clinical pathology

authors： Ross JS,Gray K,Gray GS,Worland PJ,Rolfe M

更新日期：2003-04-01 00:00:00

abstract：:Counterimmunoelectrophoresis was used to detect Cryptococcus neoformans capsular polysaccharide in the body fluids of infected patients. Using rabbit anti-C. neoformans A15 globulin, counterimmunoelectrophoresis detected 1.25 microgram of purified cryptococcal polysaccharide per ml of cerebrospinal fluid (CSF) or urin...

journal_title：American journal of clinical pathology

authors： Maccani JE

更新日期：1977-07-01 00:00:00

abstract：OBJECTIVES:Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) is a heterogeneous disorder defined by morphologic, genetic, or clinical features. Genetic abnormalities associated with AML-MRC are often associated with adverse prognostic features, and many cases are preceded by a myelodysplastic syndrom...

journal_title：American journal of clinical pathology

authors： Vardiman J,Reichard K

更新日期：2015-07-01 00:00:00

abstract：:We report 2 cases of splenic postchemotherapy histiocyte-rich pseudotumor. Each patient had a history of diffuse large B-cell lymphoma, treated with multiagent chemotherapy. Computed tomography scans performed on both patients showed splenic masses. A positron emission tomography scan performed on 1 patient showed inc...

journal_title：American journal of clinical pathology

authors： Chandra P,Wen YH,Tuli S,Raphael BG,Amorosi EL,Medeiros LJ,Ibrahim S

更新日期：2009-09-01 00:00:00

abstract：:Hematogones (HGs) comprise a B-lineage lymphoid precursor cell population in the bone marrow (BM) that may simulate acute lymphoblastic leukemia or lymphoma. Increased numbers of HGs have been noted in children, but few reports describe their occurrence in adults. We identified 13 adult patients with significant numbe...

journal_title：American journal of clinical pathology

authors： Davis RE,Longacre TA,Cornbleet PJ

更新日期：1994-08-01 00:00:00

abstract：:In order to determine the significance of 40% or more leukemic cells in hand-mirror configuration in the bone marrow (hand-mirror cell leukemia), eight of 34 cases of acute lymphoblastic leukemia and one of 17 cases of acute myeloblastic leukemia were collected from a six-year period. Five of the eight patients who ha...

journal_title：American journal of clinical pathology

authors： Glassy EF,Sun NC,Okun DB

更新日期：1980-11-01 00:00:00

abstract：:We describe the development and testing of a novel pre-sign-out quality assurance tool for case diagnoses that allows for the random review of a percentage of cases by a second pathologist before case verification and release of the final report. The tool incorporates the ability to record and report levels of diagnos...

journal_title：American journal of clinical pathology

authors： Owens SR,Dhir R,Yousem SA,Kelly SM,Piccoli A,Wiehagen L,Lassige K,Parwani AV

更新日期：2010-06-01 00:00:00

abstract：:"Low-grade squamous intraepithelial lesion (LSIL), cannot exclude high-grade squamous intraepithelial lesion" (LSIL-H) is an increasingly used, equivocal interpretive category in gynecologic cytology. In an effort to evaluate its potential usefulness as a measure of quality assurance, we studied patterns of use of the...

journal_title：American journal of clinical pathology

authors： Nishino HT,Wilbur DC,Tambouret RH

更新日期：2012-08-01 00:00:00

abstract：:The 1973 Comprehensive Blood Bank Survey Program of the College of American Pathologists was administered to 2,200 laboratories and blood banks throughout the United States. The results showed a considerable increase in the accuracy of the testing and in the performance of reagents. Accuracy of ABO testing was 99.3%; ...

journal_title：American journal of clinical pathology

authors： Myhre BA,Koepke JA

更新日期：1975-06-01 00:00:00

abstract：OBJECTIVES:Preanalytical factors, such as hemolysis, affect many components of a test panel. Machine learning can be used to recognize these patterns, alerting clinicians and laboratories to potentially erroneous results. In particular, machine learning might identify which cases of elevated potassium from a point-of-c...

journal_title：American journal of clinical pathology

authors： Benirschke RC,Gniadek TJ

更新日期：2020-07-07 00:00:00

abstract：OBJECTIVES:To evaluate the impact of implementing the dual interpretation of atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion (ASC-H) and low-grade squamous intraepithelial lesion (LSIL) after the Bethesda System 2014 and to compare it with other indeterminate interpretations. METHODS...

journal_title：American journal of clinical pathology

authors： Goyal A,Patel AP,Dilcher TL,Alperstein SA

更新日期：2020-09-08 00:00:00