Low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion: a category with an increased outcome of high-grade lesions: use as a quality assurance measure.

abstract：:Four cases of acute myelofibrosis are contrasted to three cases of acute megakaryocytic leukemia. The cases were clinically indistinguishable. Light microscopic examination of hematoxylin and eosin-stained bone marrow biopsy specimens from the cases of acute myelofibrosis showed a trilinear proliferation of mature and...

journal_title：American journal of clinical pathology

authors： Hruban RH,Kuhajda FP,Mann RB

更新日期：1987-11-01 00:00:00

abstract：:Characteristically, mantle cell lymphoma (MCL) expresses surface immunoglobulin (sIg), CD19, CD20, and CD5 and lacks CD10 and CD23. Rare CD5-MCL variants have been described. This report describes a case of leukemic MCL with morphologically and immunophenotypically distinct classic MCL and blastoid-variant MCL (BV-MCL...

journal_title：American journal of clinical pathology

authors： Morice WG,Hodnefield JM,Kurtin PJ,Hanson CA

更新日期：2004-07-01 00:00:00

abstract：:This report concerns a particular benign histologic variant of Hodgkin's disease, the lymphocyte-predominant category of the Rye classification. The group of 24 cases, all involving localized disease, was first reported in 1960, and is now reappraised, incorporating subsequent data. The interpretations of the original...

journal_title：American journal of clinical pathology

authors： Wright CJ

更新日期：1977-06-01 00:00:00

abstract：:Thirty-five patients with dermatopathic lymphadenopathy, 12 with (9 patients and 3 follow-up) and 23 without associated mycosis fungoides, and 7 controls with 26 lymph nodes were studied by light microscopic examination and immunostaining for S-100 protein. Fourteen of these cases were examined ultrastructurally. The ...

journal_title：American journal of clinical pathology

authors： Herrera GA

更新日期：1987-02-01 00:00:00

abstract：:Laboratory Branch Complement Fixation and FIAX (fluorescence immunoassay) were compared for the detection of antibodies to herpes simplex virus and cytomegalovirus in human sera. Of 68 sera with no antibodies to herpes simplex virus by complement fixation, one specimen was positive by FIAX (specificity, 98.6%). Of 75 ...

journal_title：American journal of clinical pathology

authors： Segar JE,Smith TF,Ilstrup DM

更新日期：1981-03-01 00:00:00

abstract：:The measurement of beta-thromboglobulin (BTG) and platelet lactic dehydrogenase (LDH) as markers for alpha-granule release and platelet lysis, respectively, has been reported to correlate with the amount of damage incurred during the preparation and storage of platelet concentrates. We compared the concentrations of t...

journal_title：American journal of clinical pathology

authors： Kalmin ND,Wilson MJ,Liles BA

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVES:B-lymphoblastic leukemia (B-LBL) arising in patients with chronic lymphocytic leukemia (CLL) is exceedingly rare and poorly characterized. METHODS:We describe four patients with CLL and concurrent or subsequent B-LBL diagnosed by morphologic, immunophenotypic, cytogenetic, and molecular analysis and reviewe...

journal_title：American journal of clinical pathology

authors： Chakhachiro Z,Yin CC,Abruzzo LV,Aladily TN,Barron LL,Banks HE,Thomas DA,Keating M,Medeiros LJ,Huh YO

更新日期：2015-08-01 00:00:00

abstract：:Eight cases are reported of an unusual breast lesion consisting of dense intralobular, perilobular, and perivascular lymphocytic infiltrates associated with lobular atrophy and sclerosis. Immunologic studies on paraffin-embedded tissue (seven cases) and frozen tissue (two cases) demonstrated a predominance of B-cells ...

journal_title：American journal of clinical pathology

authors： Schwartz IS,Strauchen JA

更新日期：1990-06-01 00:00:00

abstract：:Three cases of infantile hemangioendothelioma were immunohistochemically studied with the use of antibodies against von Willebrand factor (vWF), Ulex europaeus I lectin (UEA I), vimentin, thrombomodulin (TM), and actin, as endothelial cell (EC) markers. Because of a broad variety of histologic features, the growth pat...

journal_title：American journal of clinical pathology

authors： Yasunaga C,Sueishi K,Ohgami H,Suita S,Kawanami T

更新日期：1989-06-01 00:00:00

abstract：:Quantitative measurements of constituent concentrations of Survey specimens are generally recorded to the nearest integer or to the nearest tenth. Questions have arisen as to whether this degree of rounding of measurements is appropriate when available laboratory equipment can determine results more precisely. Statist...

journal_title：American journal of clinical pathology

authors： Williams GW,Schork MA

更新日期：1976-07-01 00:00:00

abstract：:We compared a rapid, point-of-care multimarker protocol with a single and serial troponin I (TnI)-only protocol in 5,244 patients admitted to the emergency department with chest pain. The diagnosis of acute myocardial infarction (AMI) was based on a doubling myoglobin level accompanied by at least a 50% increase in th...

journal_title：American journal of clinical pathology

authors： Straface AL,Myers JH,Kirchick HJ,Blick KE

更新日期：2008-05-01 00:00:00

abstract：:The volume of data contained in a data warehouse represents a potential resource to provide the basis for detailed and specific reference intervals. Routine chemistry panel testing data were derived from an outreach laboratory patient population of 438,180 people and then screened by multiple data filters to identify ...

journal_title：American journal of clinical pathology

authors： Bock BJ,Dolan CT,Miller GC,Fitter WF,Hartsell BD,Crowson AN,Sheehan WW,Williams JD

更新日期：2003-11-01 00:00:00

abstract：:Apocrine carcinoma (AC) is an uncommon, poorly characterized type of breast tumor. In this review, 55 patients with intraductal (ID) AC and 17 patients with infiltrating (IF) AC were analyzed retrospectively to define the histologic features and clinical course of this neoplasm. Recurrences in the breast occurred in 3...

journal_title：American journal of clinical pathology

authors： Abati AD,Kimmel M,Rosen PP

更新日期：1990-10-01 00:00:00

abstract：:The authors analyzed the frequency of immunophenotypic abnormalities in 1,474 cases of routinely fixed, paraffin-embedded B-lineage non-Hodgkin's lymphomas. B-lineage was determined by immunoreactivity for CD20 (L26, 92%); CD45RA (4KB5, an additional 3%) or immunoglobulin (Ig) light chain restriction (remaining 5%). C...

journal_title：American journal of clinical pathology

authors： Gelb AB,Rouse RV,Dorfman RF,Warnke RA

更新日期：1994-12-01 00:00:00

abstract：:The authors have examined the sensitivity and detection efficiency of the three peroxidase methods that currently have the widest application in diagnostic immunohistochemistry: the peroxidase-antiperoxidase (PAP), the avidin-biotin complex (ABC), and the labeled avidin-biotin (LAB) methods. Sensitivity was evaluated ...

journal_title：American journal of clinical pathology

authors： Elias JM,Margiotta M,Gaborc D

更新日期：1989-07-01 00:00:00

abstract：:To determine the diagnostic significance of the kappa/lambda ratio in germinal center (GC) B cells in Hashimoto thyroiditis (HT), we used 4-color flow cytometry to immunophenotype 27 samples (21 patients) of well-characterized HT B-cell clonality was analyzed further by polymerase chain reaction (PCR) of the immunoglo...

journal_title：American journal of clinical pathology

authors： Chen HI,Akpolat I,Mody DR,Lopez-Terrada D,De Leon AP,Luo Y,Jorgensen J,Schwartz MR,Chang CC

更新日期：2006-01-01 00:00:00

abstract：:Fluorescence in situ hybridization (FISH) and immunohistochemical analysis for assessment of HER-2 status in breast carcinomas are discordant in a significant proportion of cases with equivocal (2+) immunostaining. To evaluate the role of intratumoral heterogeneity and degree of amplification, we performed additional ...

journal_title：American journal of clinical pathology

authors： Lewis JT,Ketterling RP,Halling KC,Reynolds C,Jenkins RB,Visscher DW

更新日期：2005-08-01 00:00:00

abstract：:Cellular and humoral immunity combine to determine the outcome following exposure to hepatitis virus and are implicated in the proposed pathogenetic mechanism for acute and chronic hepatitis. Although antibody to HBsAg is found in virtually all following recovery from hepatitis B, a cell-mediated response to HBsAg can...

journal_title：American journal of clinical pathology

authors： Lee WM

更新日期：1976-05-01 00:00:00

abstract：OBJECTIVES:Solid tumor metastases to the pancreas are rare, and only limited literature on the topic is available. In this retrospective study, we reviewed 107 cases of solid tumor metastases to the pancreas diagnosed by fine-needle aspiration (FNA) from 2005 to 2019. METHODS:Information including the patients' clinic...

journal_title：American journal of clinical pathology

authors： Hou T,Stewart JM,Lee JH,Gan Q

更新日期：2020-10-13 00:00:00

abstract：:A 76-year-old white man previous diagnosed as having Waldenstrom's macroglobulinemia continued with persistent fevers and sweats for two and a half years. Recently, repeated automated differentials during 11 days of hospitalization failed to note any intracellular inclusions in the RBCs. Blood sent to the Microbiology...

journal_title：American journal of clinical pathology

authors： Bruckner DA,Garcia LS,Shimizu RY,Goldstein EJ,Murray PM,Lazar GS

更新日期：1985-04-01 00:00:00

abstract：:Human intravenous immunoglobulins prepared by the cold ethanol fractionation technique of Cohn are considered safe with respect to infectivity. However, there have been several instances of transmission of both hepatitis B and non-A,non-B hepatitis viruses after administration of intravenous immunoglobulins. To determ...

journal_title：American journal of clinical pathology

authors： Dodd LG,McBride JH,Gitnick GL,Howanitz PJ,Rodgerson DO

更新日期：1992-01-01 00:00:00

abstract：:Immunohistochemical analysis, the most efficient way of assaying for HER-2/neu overexpression in patients with invasive breast cancer, is subject to variation in sensitivity and evaluation when used in multiple laboratories. Cell lines with differing but constant levels of HER-2/neu expression have been advocated as s...

journal_title：American journal of clinical pathology

authors： Rhodes A,Borthwick D,Sykes R,Al-Sam S,Paradiso A

更新日期：2004-07-01 00:00:00

abstract：:HER2 overexpression and amplification have been studied as a therapeutic and prognostic target in a number of human cancers, including esophageal, gastric, and colorectal adenocarcinomas. However, HER2 status has not been well investigated in primary small intestinal adenocarcinoma, probably because of its rarity. In ...

journal_title：American journal of clinical pathology

authors： Chan OT,Chen ZM,Chung F,Kawachi K,Phan DC,Himmelfarb E,Lin F,Perry A,Wang HL

更新日期：2010-12-01 00:00:00

abstract：:Five hundred consecutive isolates of viridans streptococci were identified to the species level in an effort to determine their distribution and incidence in routine clinical specimens. Viridans streptococci accounted for significant percentages of streptococcal isolates from urine, wounds, body fluids, and blood. The...

journal_title：American journal of clinical pathology

authors： Ruoff KL,Fishman JA,Calderwood SB,Kunz LJ

更新日期：1983-12-01 00:00:00

abstract：:The authors studied the performance of four measures of laboratory turnaround time: the mean, median, 90th percentile, and proportion of tests reported within a predetermined cut-off interval (proportion of acceptable tests [PAT]). Measures were examined with the use of turnaround time data from 11,070 stat partial th...

journal_title：American journal of clinical pathology

authors： Valenstein PN,Emancipator K

更新日期：1989-04-01 00:00:00

abstract：:We determined whether there were additional diagnostic findings in additional level sections performed on polyps with no pathologic diagnosis (NPD) or those in which only lymphoid aggregates (LAs) were seen initially and determined the level at which findings were identified. All colorectal biopsy specimens submitted ...

journal_title：American journal of clinical pathology

authors： Nash JW,Niemann T,Marsh WL,Frankel WL

更新日期：2002-03-01 00:00:00

abstract：:This article describes the occurrence of a coenurus, the encysted larval stage of a cestode of the genus Multiceps, within the axilla of a 40-year-old Nigerian woman. The patient had a history of intraductal carcinoma of the breast two years prior to the finding of an ipsilateral axillary mass. Pathologic evaluation o...

journal_title：American journal of clinical pathology

authors： Kurtycz DF,Alt B,Mack E

更新日期：1983-11-01 00:00:00

abstract：:The resources needed to operate a clinical chemistry laboratory are known only as rough approximations. In order to gather more information about these resources, a 13-page questionnaire was completed by 50 pathology departments of which 38 departments provided adequate information about their clinical chemistry secti...

journal_title：American journal of clinical pathology

authors： Elin RJ,Robertson EA,Sever G

更新日期：1982-12-01 00:00:00

abstract：OBJECTIVES:Meningiomas usually can be readily diagnosed on H&E alone, although occasionally immunohistochemistry (IHC) confirmation is desirable. Studies exploring the diagnostic utility of either podoplanin (D2-40) or E-cadherin IHC in meningiomas have conflicted, and no studies exist in which the two IHCs have been u...

journal_title：American journal of clinical pathology

authors： Mrachek EK,Davis D,Kleinschmidt-DeMasters BK

更新日期：2015-12-01 00:00:00

abstract：:Because of the unusual presentation of pernicious anemia in many black women, a further characterization of this disease among the different racial groups was undertaken. The following were found. (1) Black women under the age of 50 years had a significantly lower prevalence of anti-parietal cell antibody than did "Eu...

journal_title：American journal of clinical pathology

authors： Carmel R,Ozturk G,Johnson CS,Tung KS,Terasaki PI

更新日期：1981-03-01 00:00:00