B-Lymphoblastic Leukemia in Patients With Chronic Lymphocytic Leukemia: A Report of Four Cases.

abstract：OBJECTIVES:To compare next-generation sequencing (NGS) platforms with mutation-specific analysis platforms in a clinical setting, in terms of sensitivity, mutation specificity, costs, capacity, and ease of use. METHODS:We analyzed 25 formalin-fixed, paraffin-embedded lung cancer samples of different size and tumor per...

journal_title：American journal of clinical pathology

authors： Hinrichs JW,van Blokland WT,Moons MJ,Radersma RD,Radersma-van Loon JH,de Voijs CM,Rappel SB,Koudijs MJ,Besselink NJ,Willems SM,de Weger RA

更新日期：2015-04-01 00:00:00

abstract：:The morphologic appearances of regional lymph nodes in radical mastectomy specimens obtained from 303 women entered into a prospective study of invasive breast cancer were categorized into patterns that have been considered to reflect immunologic function. An attempt was made to correlate these with 31 other histologi...

journal_title：American journal of clinical pathology

authors： Fisher ER,Gregorio R,Redmond C,Dekker A,Fisher B

更新日期：1976-01-01 00:00:00

abstract：:Primary thymic epithelial neoplasms have been the subject of much controversy in recent years owing to the difficulties posed by these tumors for precise histopathologic typing and prognostication. A number of classification schemes using different terminology have been proposed, none of which has satisfactorily manag...

journal_title：American journal of clinical pathology

authors： Suster S,Moran CA

更新日期：1999-06-01 00:00:00

abstract：:To assess the diagnostic accuracy of margin evaluation of melanocytic lesions using en face frozen sections compared with standard paraffin-embedded sections, we studied 2 sets of lesions in which en face frozen sections were used for analysis of surgical margins (13 from malignant melanomas [MMs] and 10 from nonmelan...

journal_title：American journal of clinical pathology

authors： Prieto VG,Argenyi ZB,Barnhill RL,Duray PH,Elenitsas R,From L,Guitart J,Horenstein MG,Ming ME,Piepkorn MW,Rabkin MS,Reed JA,Selim MA,Trotter MJ,Johnson MM,Shea CR

更新日期：2003-08-01 00:00:00

abstract：:Tumors and pseudotumors of the liver account for fewer than 2% of the tumors in children and vary considerably in incidence throughout the pediatric age range, with hepatoblastoma, infantile hemangioendothelioma, and mesenchymal hamartoma seen most frequently in the first 2 years of life and hepatocellular carcinoma, ...

journal_title：American journal of clinical pathology

authors： Stocker JT

更新日期：1998-04-01 00:00:00

abstract：:For quality-control purposes, federal regulations require cytology laboratories to compare Papanicolaou smear and cervical biopsy reports, if available, and determine the cause of any discrepancies. The authors reviewed 56,497 cervicovaginal smears, of which 1,582 (2.8%) had a subsequent cervical biopsy or endocervica...

journal_title：American journal of clinical pathology

authors： Joste NE,Crum CP,Cibas ES

更新日期：1995-01-01 00:00:00

abstract：:An automated fluorescent immunoassay system (FIAX) was compared with complement fixation (CF) for measuring antibodies to cytomegalovirus (CMV) and herpes simplex virus (HSV) in clinical specimens. Compared with CF the specificity of FIAX (ability to detect a negative titer) was 95% for CMV and 92% for HSV. The sensit...

journal_title：American journal of clinical pathology

authors： Friedman HM,Tustin NB,Hitchings MM,Plotkin SA

更新日期：1981-09-01 00:00:00

abstract：:To our knowledge, there are no universally accepted, evidence-based guidelines for how to resolve the HER2 status of tumors demonstrating equivocal amplification. The present study was based on 17 breast core biopsy specimens demonstrating invasive carcinoma with equivocal HER2 amplification, defined as an HER2/chromo...

journal_title：American journal of clinical pathology

authors： Striebel JM,Bhargava R,Horbinski C,Surti U,Dabbs DJ

更新日期：2008-03-01 00:00:00

abstract：:To determine the diagnostic significance of the kappa/lambda ratio in germinal center (GC) B cells in Hashimoto thyroiditis (HT), we used 4-color flow cytometry to immunophenotype 27 samples (21 patients) of well-characterized HT B-cell clonality was analyzed further by polymerase chain reaction (PCR) of the immunoglo...

journal_title：American journal of clinical pathology

authors： Chen HI,Akpolat I,Mody DR,Lopez-Terrada D,De Leon AP,Luo Y,Jorgensen J,Schwartz MR,Chang CC

更新日期：2006-01-01 00:00:00

abstract：:Encephalitozoon (Septata) intestinalis affects AIDS patients with CD4 counts <100/microL, causing intestinal and disseminated disease. It must be distinguished from the more common intestinal microsporidian, Enterocytozoon bieneusi, and from other microsporidia of extraintestinal tissues, such as Encephalitozoon helle...

journal_title：American journal of clinical pathology

authors： Chu P,West AB

更新日期：1996-11-01 00:00:00

abstract：:Histologic findings in liver biopsy specimens obtained from 88 patients before and one and two years after end-to-end jejunoileal bypass are compared. In addition to the expected fatty changes, mild changes of centrilobular, pericellular fibrosis were present in the initial biopsies in 8.6%; a year later they had beco...

journal_title：American journal of clinical pathology

authors： Marubbio AT Jr,Buchwald H,Schwartz MZ,Varco R

更新日期：1976-10-01 00:00:00

abstract：:Three activated partial thromboplastin time (APTT) reagent test systems, General Diagnostics Automated APTT, American Dade Actin FS, and Pacific Hemostasis (Thromboscreen KAPTT) reagent, containing different activators for the APTT assay, were evaluated for their precision and sensitivity to factor deficiencies in the...

journal_title：American journal of clinical pathology

authors： Turi DC,Peerschke EI

更新日期：1986-01-01 00:00:00

abstract：:Intrauterine clostridial infections have historically been associated with puerperal sepsis, often subsequent to instrumented abortions. Isolated reports have been associated with a malignant neoplasm or degenerating leiomyoma, most often after instrumentation, radiation therapy, or chemotherapy. In these cases, well-...

journal_title：American journal of clinical pathology

authors： Hogan SF,Ireland K

更新日期：1989-01-01 00:00:00

abstract：:Tissue repositories maintained by pathology departments represent an abundant resource of clinically annotated human specimens. The storage expenses associated with pathology archives are known to administrators of most pathology departments. However, such basic repository characteristics as the quality of stored mate...

journal_title：American journal of clinical pathology

authors： Smith MA,Barnes EL,Chiosea SI

更新日期：2011-05-01 00:00:00

abstract：:The Leu-8 antigen is found on the surface of many hematologic cells, including many T- and B-lymphocytes. With the use of a frozen-section immunoperoxidase technic, 152 B-cell non-Hodgkin's lymphomas were examined for Leu-8 expression. Of these lymphomas, 53% expressed Leu-8. Subclassification of the lymphomas with th...

journal_title：American journal of clinical pathology

authors： Michie SA,Garcia CF,Strickler JG,Dailey MO,Rouse RV,Warnke RA

更新日期：1987-10-01 00:00:00

abstract：:Plasma biomarker analysis requires intact unbiased starting material. We analyzed the effects on plasma protein profiles of protease inhibitor cocktails and preprocessing storage. Plasma from 12 healthy subjects collected with and without protease inhibitors was prepared immediately and after 2 hours of room temperatu...

journal_title：American journal of clinical pathology

authors： Ayache S,Panelli M,Marincola FM,Stroncek DF

更新日期：2006-08-01 00:00:00

abstract：:We evaluated a comprehensive deidentification engine at the University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA, that uses a complex set of rules, dictionaries, pattern-matching algorithms, and the Unified Medical Language System to identify and replace identifying text in clinical reports while preserving ...

journal_title：American journal of clinical pathology

authors： Gupta D,Saul M,Gilbertson J

更新日期：2004-02-01 00:00:00

abstract：:Hairy cell populations of greater than 90 purity were prepared from six samples obtained from four patients with leukemic reticuloendotheliosis (LRE). These then were analyzed for surface immunoglobulin (SIg) and antigens specified by a panel of monoclonal antibodies. The hairy cells from all patients displayed SIg an...

journal_title：American journal of clinical pathology

authors： Janckila AJ,Stelzer GT,Wallace JH,Yam LT

更新日期：1983-04-01 00:00:00

abstract：:We surveyed 271 laboratories participating in a quality assessment program to ascertain whether the use of a calibration curve for determining the international normalized ratio (INR) would improve interlaboratory accuracy and precision. Lyophilized warfarinized samples with INR values assigned through manual calibrat...

journal_title：American journal of clinical pathology

authors： Brien WF,Baskerville JC,Taberner DA,Crawford L

更新日期：1999-02-01 00:00:00

abstract：:Using digital cell image analysis performed on Feulgen-stained nuclei, the nuclear characteristics of prostatic neoplasia, ranging from benign (benign prostatic hyperplasia [BPH]), through dysplastic (prostatic intraepithelial neoplasia [PIN] 1-3), to carcinoma were studied. Four histopathologic groups were studied: g...

journal_title：American journal of clinical pathology

authors： Petein M,Michel P,van Velthoven R,Pasteels JL,Brawer MK,Davis JR,Nagle RB,Kiss R

更新日期：1991-11-01 00:00:00

abstract：:We previously reported 24 cases of marrow fibrin-ring granuloma (FRG) encountered in 1 institution and concluded that, contrary to previous studies showing marrow FRG as a diagnostic marker for Q fever, Epstein-Barr virus (EBV) was the most common proven cause of such FRG. The present study characterized patients with...

journal_title：American journal of clinical pathology

authors： Chung HJ,Chi HS,Jang S,Park CJ

更新日期：2010-02-01 00:00:00

abstract：:Pulmonary alveolar proteinosis (PAP) is an uncommon disease in which alveoli are progressively filled with surfactant-related material. Although a definitive diagnosis is usually made by an open lung biopsy, bronchoalveolar lavage (BAL) cytology may play a decisive role in the clinical work-up of these patients, and, ...

journal_title：American journal of clinical pathology

authors： Burkhalter A,Silverman JF,Hopkins MB 3rd,Geisinger KR

更新日期：1996-10-01 00:00:00

abstract：:The authors report here a case of lymphoepithelial cystic lesion (LECL) of unknown origin in the mediastinum, which is closely related to a signet-ring cell adenocarcinoma. A 73-year-old man presented with a mass as revealed on a chest x-ray. During surgical operation, a solid, well-circumscribed and encapsulated 9 X ...

journal_title：American journal of clinical pathology

authors： Ishimaru Y,Shibata Y,Ohkawara S,Ohshima H,Kihara S

更新日期：1989-12-01 00:00:00

abstract：:The recent clinical and commercial success of anticancer antibodies such as rituximab and trastuzumab has created great interest in antibody-based therapeutics for hematopoietic malignant neoplasms and solid tumors. Given the likelihood of lower toxic effects of antibodies that target tumor cells and have limited impa...

journal_title：American journal of clinical pathology

authors： Ross JS,Gray K,Gray GS,Worland PJ,Rolfe M

更新日期：2003-04-01 00:00:00

abstract：:Congenital-infantile fibrosarcoma (CIFS) is a relatively indolent sarcoma that should be distinguished from more aggressive spindle cell sarcomas of childhood. CIFSs have been found to have a novel recurrent reciprocal translocation t(12;15)(p13;q25) resulting in the gene fusion ETV6-NTRK3 (ETS variant gene 6; neurotr...

journal_title：American journal of clinical pathology

authors： Sheng WQ,Hisaoka M,Okamoto S,Tanaka A,Meis-Kindblom JM,Kindblom LG,Ishida T,Nojima T,Hashimoto H

更新日期：2001-03-01 00:00:00

abstract：:Two commercial enzyme-linked immunosorbent assays (EIAs) for human immunodeficiency virus (HIV) antigens were evaluated for sensitivity and reproducibility by use of supernatant fluid from cell cultures of peripheral mononuclear cells of 18 patients with acquired immunodeficiency syndrome (AIDS) and 12 asymptomatic HI...

journal_title：American journal of clinical pathology

authors： Jackson JB,Sannerud K,Rhame FS,Balfour HH Jr

更新日期：1988-06-01 00:00:00

abstract：:We determined whether there were additional diagnostic findings in additional level sections performed on polyps with no pathologic diagnosis (NPD) or those in which only lymphoid aggregates (LAs) were seen initially and determined the level at which findings were identified. All colorectal biopsy specimens submitted ...

journal_title：American journal of clinical pathology

authors： Nash JW,Niemann T,Marsh WL,Frankel WL

更新日期：2002-03-01 00:00:00

abstract：:The authors have developed an immunoalkaline phosphatase method and have applied it with success to the study of blood cells. They have now observed that macrophages in tissues and in serous effusions may be nonspecifically stained when immunoalkaline phosphatase methods are used. A systematic study of this endogenous...

journal_title：American journal of clinical pathology

authors： Janckila AJ,Yam LT,Li CY

更新日期：1985-10-01 00:00:00

abstract：:The involvement of Nonspecific Crossreacting Antigen (NCA) in the immunohistological demonstration of Carcino Embryonic Antigen (CEA) in 56 benign and 92 malignant lesions of the breast was analyzed. For this purpose, the authors utilized both polyclonal antisera and monoclonal antibodies. Polyclonal anti-CEA sera wer...

journal_title：American journal of clinical pathology

authors： Nap M,Keuning H,Burtin P,Oosterhuis JW,Fleuren G

更新日期：1984-11-01 00:00:00

abstract：OBJECTIVES:Superficial pleomorphic liposarcoma (PL) has a favorable prognosis compared to deeply seated PL. Given developments in the classification of lipomatous neoplasms, we reappraised a series of cases. METHODS:Retrospective clinicopathologic evaluation and genome-wide single-nucleotide polymorphism (SNP) microar...

journal_title：American journal of clinical pathology

authors： Berg SH,Massoud CM,Jackson-Cook C,Boikos SA,Smith SC,Mochel MC

更新日期：2020-08-05 00:00:00