To step or not to step: an approach to clinically diagnosed polyps with no initial pathologic finding.

Abstract:

:We determined whether there were additional diagnostic findings in additional level sections performed on polyps with no pathologic diagnosis (NPD) or those in which only lymphoid aggregates (LAs) were seen initially and determined the level at which findings were identified. All colorectal biopsy specimens submitted with a clinical diagnosis of polyp during a 6-month period were included (N = 733). Initially, 3 level sections were cut for each polyp, and if a cause for the polyp was found, no additional levels were evaluated. If LAs or no cause for the polyp was found, 5 additional levels through each block were examined. Any diagnostic findings and the level at which they were identified were recorded. A discrete cause for the polyp was identified in routine levels in 574 cases (78.3%). Deeper levels were performed in 159: 23 for clarification of a suspected diagnosis, 38 for LAs, and 98 for NPD. Findings were identified in 31 (22.8%) of 136 stepped for LA or NPD with neoplastic findings in 13 (9.6%). Most diagnoses were identified in levels 4 or 5, but tubular adenomas were found in levels 7 and 8. These results support level sectioning specimens submitted as polyps with NPD or LAs on initial sections.

journal_name

Am J Clin Pathol

authors

Nash JW,Niemann T,Marsh WL,Frankel WL

doi

10.1309/27NQ-A1R2-DQ41-20Y7

subject

Has Abstract

pub_date

2002-03-01 00:00:00

pages

419-23

issue

3

eissn

0002-9173

issn

1943-7722

journal_volume

117

pub_type

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