Phenotypic heterogeneity of B cells in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma.

abstract：:We sought to determine whether a group of cases that was relatively high in disagreements and subsequent amendments could be identified and targeted for blinded review. During a 4-year period, 8,916 surgical pathology and nongynecologic cytology cases were subjected to blinded review; of these, there were 616 disagree...

journal_title：American journal of clinical pathology

authors： Renshaw AA,Gould EW

更新日期：2006-11-01 00:00:00

abstract：:Borrelia burgdorferi is difficult to detect in routine biopsy material from patients with skin lesions of borreliosis. In this study, a new immunohistochemical method, focus floating microscopy (FFM), was developed to detect B burgdorferi in tissue sections and was compared with polymerase chain reaction (PCR). By usi...

journal_title：American journal of clinical pathology

authors： Eisendle K,Grabner T,Zelger B

更新日期：2007-02-01 00:00:00

abstract：:Fungal organisms morphologically resembling Candida were found in one third of 72 consecutive surgically resected gastric ulcers. In over half of these cases the organisms were present in the mycelial form. Large numbers of fungi forming clusters were found in 13 cases (18%) and were associated with a surprisingly hig...

journal_title：American journal of clinical pathology

authors： Katzenstein AL,Maksem J

更新日期：1979-02-01 00:00:00

abstract：:Conventional cytogenetic studies have suggested that trisomy 12 may be a characteristic nonrandom numerical chromosome anomaly in benign ovarian tumors, particularly sex cord-stromal tumors. To confirm this finding, and to avoid possible culture artifact introduced during cytogenetic analysis, the authors performed fl...

journal_title：American journal of clinical pathology

authors： Persons DL,Hartmann LC,Herath JF,Keeney GL,Jenkins RB

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVES:This session of the 2013 Society of Hematopathology/European Association for Haematopathology Workshop was dedicated to B-acute lymphoblastic leukemia (B-ALL)/lymphoblastic lymphoma (LBL) with recurrent translocations and not otherwise specified. METHODS:In this review, we summarize the cases discussed duri...

journal_title：American journal of clinical pathology

authors： Loghavi S,Kutok JL,Jorgensen JL

更新日期：2015-09-01 00:00:00

abstract：:Although red blood cell (RBC) antigen typing by agglutination is generally useful, several situations exist where this approach is difficult or impossible. For example, following a massive transfusion, a patient's residual RBCs are mixed with transfused normal donor RBCs. In this case, typing by hemagglutination prima...

journal_title：American journal of clinical pathology

authors： Eshleman JR,Shakin-Eshleman SH,Church A,Kant JA,Spitalnik SL

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVES:Nucleic acid amplification tests on formalin-fixed, paraffin-embedded (FFPE) tissue specimens enable Mycobacterium tuberculosis complex (MTB) detection and rapid tuberculosis diagnosis in the absence of microbiologic culture tests. We aimed to evaluate the efficacy of different polymerase chain reaction (PCR...

journal_title：American journal of clinical pathology

authors： Seo AN,Park HJ,Lee HS,Park JO,Chang HE,Nam KH,Choe G,Park KU

更新日期：2014-09-01 00:00:00

abstract：:The Department of Laboratory Medicine, University of Washington, has explored various management of organizational approaches over the past seven years. The Centralized Processing Area supported by a computerized information system has evolved from these efforts. Despite a decrease in U.W. hospital usage since 1968-69...

journal_title：American journal of clinical pathology

authors： Nussbaum B,Minckler T,Roby R,Ackerman E

更新日期：1977-02-01 00:00:00

abstract：:Transbronchoscopic biopsies of lung (transbronchial) or bronchus (endobronchial) have a high diagnostic of yield when performed by a single expert bronchoscopist or a small group of expert bronchoscopists. This procedure's diagnostic yield was evaluated in a general hospital where biopsies are performed by a diverse g...

journal_title：American journal of clinical pathology

authors： Jenkins R,Myerowitz RL,Kavic T,Slasky S

更新日期：1979-12-01 00:00:00

abstract：:We conducted this study to ascertain the prevalence of erb-b2 gene amplification in breast cancer specimens read as 2+ in immunohistochemical analysis. Slides from patients with metastatic or recurrent breast cancer were eligible for fluorescent in situ hybridization (FISH) study if they were read as 2+ immunohistoche...

journal_title：American journal of clinical pathology

authors： Lan C,Liu JM,Liu TW,Hsu DH,Liang S,Chen JR,Peng JW

更新日期：2005-07-01 00:00:00

abstract：:The authors illustrate two neoplasms arising in the pretibial soft tissue that are histologically identical to adamantinoma of the long bones. The tumors developed in a 24-year-old woman and a 31-year-old man. Both were treated by local excision. Histologically, one tumor had a tubular pattern and one was composed of ...

journal_title：American journal of clinical pathology

authors： Mills SE,Rosai J

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVES:The metaplastic intestinal epithelium in Barrett esophagus (BE) occasionally contains Paneth cells; however, little is known regarding the prevalence and significance of Paneth cell metaplasia (PCM) in BE. METHODS:We evaluated 757 esophageal biopsy specimens with intestinal metaplasia (IM) for PCM. Outcome ...

journal_title：American journal of clinical pathology

authors： Chen W,Frankel WL,Cronley KM,Yu L,Zhou X,Yearsley MM

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:Mutations in CALR (calreticulin) have been discovered in 50% to 80% of JAK2 (Janus kinase 2) and MPL (myeloproliferative leukemia protein) wild-type patients with Philadelphia-negative myeloproliferative neoplasm (MPNs). We evaluate the performance of a monoclonal antibody for immunohistochemical detection o...

journal_title：American journal of clinical pathology

authors： Nomani L,Bodo J,Zhao X,Durkin L,Loghavi S,Hsi ED

更新日期：2016-10-01 00:00:00

abstract：:Cellular proliferation is being evaluated as an independent prognostic indicator in a variety of tumors, including non-Hodgkin's lymphomas (NHL). Although the labeling index (LI), using either tritiated thymidine or monoclonal antibodies to bromodeoxyuridine, is considered to be the gold standard of cell kinetic measu...

journal_title：American journal of clinical pathology

authors： Sebo TJ,Roche PC,Witzig TE,Kurtin PJ

更新日期：1993-06-01 00:00:00

abstract：:Squamous cell carcinoma (SCC) is by far the most common malignancy of the upper aerodigestive tract. Most conventional-type SCCs do not present the surgical pathologist with diagnostic difficulty. Certain variants, however, can histologically mimic benign and other malignant diseases. In such cases, correct diagnosis ...

journal_title：American journal of clinical pathology

authors： Stelow EB,Mills SE

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVES:Serologic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has experienced a changing landscape of available assays coupled with uncertainty surrounding performance characteristics. Studies are needed to directly compare multiple commercially available assays. METHODS:Residual serum ...

journal_title：American journal of clinical pathology

authors： Manthei DM,Whalen JF,Schroeder LF,Sinay AM,Li SH,Valdez R,Giacherio DA,Gherasim C

更新日期：2020-10-09 00:00:00

abstract：:The defined antigen substrate sphere system is a simple method for detecting antigen or antibody in the circulation. The technic is based on the coupling of antigen or antibody with Sepharose 4B beads that have been activated by cyanogen bromide. In this study the activated beads were exposed to dengue antigen in the ...

journal_title：American journal of clinical pathology

authors： Boonpucknavig S,Bunnag C,Vuttiviroj O,Nimmannitya S

更新日期：1978-09-01 00:00:00

abstract：:A multiplex polymerase chain reaction (PCR) assay using oligonucleotide primers to detect mecA and 16S ribosomal RNA gene was developed to aid in identification of methicillin-resistant staphylococci. Validation included 99 isolates of staphylococcus grouped into one of five categories: methicillin-susceptible coagula...

journal_title：American journal of clinical pathology

authors： Salisbury SM,Sabatini LM,Spiegel CA

更新日期：1997-03-01 00:00:00

abstract：:The JAK2(V617F)mutation is recurrent in polycythemia vera and essential thrombocythemia, which are myeloproliferative neoplasms frequently associated with arterial and venous thromboembolism. It has also been reported as a marker for occult myeloproliferative disorder (MPD) in patients with splanchnic venous thrombosi...

journal_title：American journal of clinical pathology

authors： Shetty S,Kulkarni B,Pai N,Mukundan P,Kasatkar P,Ghosh K

更新日期：2010-07-01 00:00:00

abstract：:This review summarizes our experience using blinded review as a method to measure quality in surgical pathology. It details the specifics about how the review is performed, the weaknesses in the method, and then summarizes our results so far. These results suggest that error rates correlate with the individual patholo...

journal_title：American journal of clinical pathology

authors： Renshaw AA,Gould EW

更新日期：2007-01-01 00:00:00

abstract：:RhD determination in pregnant women is critical to facilitate Rh immune globulin prophylaxis for RhD-negative women. A single amino acid change in the RhD antigen can cause epitope loss, giving rise to "partial D" variants. Women with some partial D variants may develop anti-D against the missing epitope after pregnan...

journal_title：American journal of clinical pathology

authors： Wang D,Lane C,Quillen K

更新日期：2010-09-01 00:00:00

abstract：Objectives:To analyze the economic impact of testing for activated protein C resistance (APC-R) due to factor V Leiden (FVL) mutation with APC-R with reflexive FVL genotyping (algorithmic approach) or genotyping alone. Methods:OptumLabs Data Warehouse (OLDW) data were used to assess testing approaches. Insurance claim...

journal_title：American journal of clinical pathology

authors： Perez Botero J,Majerus JA,Strege AK,Johnson RD,Chen D,Pruthi RK

更新日期：2017-06-01 00:00:00

abstract：:An assessment of the infrequently performed protein-bound iodine determinations (PBI) and thyroxine (T4) determinations by column chromatography is presented after analysis of data contributed by participants in the 1976 College of American Pathologists Chemistry Survey Programs. The two technics yield comparable mean...

journal_title：American journal of clinical pathology

authors： Thiessen MM,Batsakis JG,Neuhoff J,Thomas BP

更新日期：1978-09-01 00:00:00

abstract：:Serrated adenomas are the precursors of at least 5.8% of colorectal cancers; otherwise little is known of their clinical significance in comparison with conventional adenomas and hyperplastic polyps. We compared the risk of metachronous lesions in colorectal serrated adenomas, conventional adenomas, and hyperplastic p...

journal_title：American journal of clinical pathology

authors： Lazarus R,Junttila OE,Karttunen TJ,Mäkinen MJ

更新日期：2005-03-01 00:00:00

abstract：:Several technics are currently being used to detect hepatitis type A antigen or its antibody. These include immunoelectronmicroscopy, immune adherence, and complement fixation. This paper describes another promising technic, a microtiter solid-phase immunoradiometric assay, in which hepatitis A antigen and antibody ar...

journal_title：American journal of clinical pathology

authors： Hollinger FB,Bradley DW,Dreesman GR,Melnick JL

更新日期：1976-05-01 00:00:00

abstract：:The participant performances on the College of American Pathologists (CAP) Urine Survey specimens distributed during 1979 and 1980 for pregnancy testing are reviewed. Almost all the reagent methods used by the participants performed well on the negative specimens. Prominent differences in results on the positive speci...

journal_title：American journal of clinical pathology

authors： Biesecker JL,Rippey JH

更新日期：1981-10-01 00:00:00

abstract：:High-volume (200 ml) platelet concentrates prepared by discontinuous-flow centrifugation, with counts as high as ca. 2.0 x 10(12)/l, were stored in either 600 ml-capacity polyvinylchloride bags or 800-ml capacity polyethylene bags. Both polyvinylchloride and polyethylene bags appeared adequate for 24-hour storage of p...

journal_title：American journal of clinical pathology

authors： Rosenstein R,Lawe JE,North JG

更新日期：1980-03-01 00:00:00

abstract：OBJECTIVES:To correlate human herpesvirus 6 (HHV-6) viral load with pathologic features in graft acute hepatitis of unknown origin. METHODS:Liver frozen samples from 26 patients with graft hepatitis of unknown origin were available for HHV-6 DNA quantification. RESULTS:In 10 (38.5%) of 26 liver samples, HHV-6 DNA was...

journal_title：American journal of clinical pathology

authors： Buyse S,Roque-Afonso AM,Vaghefi P,Gigou M,Dussaix E,Duclos-Vallée JC,Samuel D,Guettier C

更新日期：2013-09-01 00:00:00

abstract：:A case of metastatic ameloblastoma of the maxilla with secondary hypercalcemia in a 54-year-old man is presented. After treatment with surgery, chemotherapy, and radiotherapy, the patient was found to have multiple metastases and severe hypercalcemia associated with high levels of parathormone-like substance in the pe...

journal_title：American journal of clinical pathology

authors： Madiedo G,Choi H,Kleinman JG

更新日期：1981-04-01 00:00:00

abstract：:The reliability of "standard" plasmas used by clinical laboratories to assay factor VIII concentrations of patients' plasmas was studied by assessing the credibility of their reference values. Two of three commercial reference plasmas were considered to be unreliable. The third commercial reference plasma appeared to ...

journal_title：American journal of clinical pathology

authors： Harper TA,Bailey EL,Chauhan K

更新日期：1981-02-01 00:00:00