A cytochemical and ultrastructural study of acute myelomonocytic leukemia exhibiting the pseudo-Chediak-Higashi anomaly of leukemia and "splinter-type" Auer rods.

abstract：:The Department of Laboratory Medicine, University of Washington, has explored various management of organizational approaches over the past seven years. The Centralized Processing Area supported by a computerized information system has evolved from these efforts. Despite a decrease in U.W. hospital usage since 1968-69...

journal_title：American journal of clinical pathology

authors： Nussbaum B,Minckler T,Roby R,Ackerman E

更新日期：1977-02-01 00:00:00

abstract：:The present immunoperoxidase study attempted to localize aldosterone and cortisol in formalin-fixed paraffin-embedded adrenal glands or tumors. Apparently, steroid substances are solubilized during routine tissue processing, and the cytoplasm of adrenal cortical cells is not stained by either antialdosterone or antico...

journal_title：American journal of clinical pathology

authors： Hsu SM,Raine L,Martin HF

更新日期：1981-01-01 00:00:00

abstract：:Subsequent to recent disclosures that low serum vitamin B12 results can appear normal using many of the current radioassay methods because of the presence of cobalamin (vitamin B12) analogues in human serum, a number of radioassay kits have become available with modified intrinsic factor preparations and claims of mea...

journal_title：American journal of clinical pathology

authors： LeFebvre RJ,Virji AS,Mertens BF

更新日期：1980-08-01 00:00:00

abstract：:Telepathology is gaining acceptance as a mode of providing pathology services to remote sites, but its economic feasibility is unknown. A dynamic robotic telepathology service between the Veterans Affairs Medical Center, Iron Mountain, MI, and the Veterans Affairs Medical Center, Milwaukee, WI, provides diagnostic ser...

journal_title：American journal of clinical pathology

authors： Agha Z,Weinstein RS,Dunn BE

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVES:B-lymphoblastic leukemia (B-LBL) arising in patients with chronic lymphocytic leukemia (CLL) is exceedingly rare and poorly characterized. METHODS:We describe four patients with CLL and concurrent or subsequent B-LBL diagnosed by morphologic, immunophenotypic, cytogenetic, and molecular analysis and reviewe...

journal_title：American journal of clinical pathology

authors： Chakhachiro Z,Yin CC,Abruzzo LV,Aladily TN,Barron LL,Banks HE,Thomas DA,Keating M,Medeiros LJ,Huh YO

更新日期：2015-08-01 00:00:00

abstract：:Hyperparathyroidism may occasionally present as a neck mass resulting from cystic change in a parathyroid adenoma. We report an unusual instance of hyperparathyroidism presenting as a palpable, but asymptomatic hyperplastic parathyroid gland cyst. We conclude that hyperplastic parathyroid glands may undergo cystic deg...

journal_title：American journal of clinical pathology

authors： Fallon MD,Haines JW,Teitelbaum SL

更新日期：1982-01-01 00:00:00

abstract：:The serum concentrations of alpha-fetoprotein of rats following experimental galactosamine-induced liver-cell necrosis accurately reflect the severity of preceding liver-cell damage as determined by elevation of serum transaminases. There is a very close correlation between the highest SGOT or SGPT serum activity foun...

journal_title：American journal of clinical pathology

authors： Sell S,Stillman D,Gochman N

更新日期：1976-11-01 00:00:00

abstract：:Although the hematopoietic origin of mast cells is very probable, the cell from which they originate is still a matter of speculation. The description of "transitional basophil/mast cells" in myeloproliferative disorders has suggested a common origin for basophils and mast cells. In a case of mast cell transformation ...

journal_title：American journal of clinical pathology

authors： Gabriel LC,Escribano LM,Marie JP,Zittoun R,Navarro JL

更新日期：1986-08-01 00:00:00

abstract：:Two unusual cases of acute lymphoblastic leukemia-hand mirror variant (ALL-HMV) are presented. One patient demonstrated a mixed immunophenotype with HLA-DR, My7, transferrin receptor surface markers, and terminal deoxynucleotidyl transferase positivity. To the authors' knowledge, this is the first ALL-HMV reported wit...

journal_title：American journal of clinical pathology

authors： Schumacher HR,Desai SN,McClain KL,Domenico DR,Dizikes GJ,Bird ML

更新日期：1989-04-01 00:00:00

abstract：:Blastomycosis generally results from inhalation of Blastomyces dermatitidis conidia following exposure to contaminated soil in an endemic area. Primary infections commonly involve the lungs, although secondary dissemination to other body sites may occur. We describe 2 cases of osseous blastomycosis in people living ou...

journal_title：American journal of clinical pathology

authors： Veligandla SR,Hinrichs SH,Rupp ME,Lien EA,Neff JR,Iwen PC

更新日期：2002-10-01 00:00:00

abstract：:The clonality of dendritic cell proliferations arising in patients with previously diagnosed B-cell non-Hodgkin lymphoma has not been determined. The highly polymorphic human androgen receptor gene (HUMARA) can be used to assess the pattern of X-chromosome inactivation and, hence, the clonality of tumors in female pat...

journal_title：American journal of clinical pathology

authors： Wu CD,Wickert RS,Williamson JE,Sun NC,Brynes RK,Chan WC

更新日期：1999-01-01 00:00:00

abstract：:The immunohistologic distribution of the feto-acinar pancreatic protein (FAP), detected by the monoclonal antibody (MoAb) J28 using an indirect immunoperoxidase technique, is described. Tests were carried out on normal adult pancreas (n = 10), chronic pancreatitis (n = 14), pancreatic adenocarcinoma (n = 17), intraabd...

journal_title：American journal of clinical pathology

authors： Albers GH,Escribano MJ,Daher N,Nap M

更新日期：1990-01-01 00:00:00

abstract：:This review summarizes our experience using blinded review as a method to measure quality in surgical pathology. It details the specifics about how the review is performed, the weaknesses in the method, and then summarizes our results so far. These results suggest that error rates correlate with the individual patholo...

journal_title：American journal of clinical pathology

authors： Renshaw AA,Gould EW

更新日期：2007-01-01 00:00:00

abstract：:The authors have developed an immunoalkaline phosphatase method and have applied it with success to the study of blood cells. They have now observed that macrophages in tissues and in serous effusions may be nonspecifically stained when immunoalkaline phosphatase methods are used. A systematic study of this endogenous...

journal_title：American journal of clinical pathology

authors： Janckila AJ,Yam LT,Li CY

更新日期：1985-10-01 00:00:00

abstract：:A number of variables thought to affect measurement of prothrombin time (PT) and partial thromboplastin time (PTT) were examined in an effort to determine more precisely their effects on these measurements. On the basis of these studies, it is proposed that blood specimens be anticoagulated with one part 3.8% (w./v.) ...

journal_title：American journal of clinical pathology

authors： Koepke JA,Rodgers JL,Ollivier MJ

更新日期：1975-11-01 00:00:00

abstract：:To study the usefulness of calretinin as an immunohistochemistry marker in the diagnosis of cardiac myxoma (CM) and the origin of myxoma cells, we examined 24 CMs and 9 fetal hearts with immunohistochemical methods on formalin-fixed paraffin-embedded tissues. We compared 24 CMs with 10 mural thrombi, 6 jaw myxomas, an...

journal_title：American journal of clinical pathology

authors： Terracciano LM,Mhawech P,Suess K,D'Armiento M,Lehmann FS,Jundt G,Moch H,Sauter G,Mihatsch MJ

更新日期：2000-11-01 00:00:00

abstract：:Sporadically, hematology analyzers generate grossly erroneous results for one or several parameters of the complete blood count (CBC) because of a characteristic or peculiarity of an individual patient specimen. This article presents three cases of relatively less well-known analytic errors of this sort, falsely eleva...

journal_title：American journal of clinical pathology

authors： Savage RA

更新日期：1989-09-01 00:00:00

abstract：:The most commonly used fixative in effusion cytology is formalin. In the present study, the immunocytochemical properties of formalin-fixed and alcohol-fixed specimens were compared to evaluate the usefulness of alcohol-fixed cytocentrifuged preparations for routine cytologic diagnosis. A total of 269 effusion samples...

journal_title：American journal of clinical pathology

authors： Ikeda K,Tate G,Suzuki T,Mitsuya T

更新日期：2011-12-01 00:00:00

abstract：:The May-Hegglin anomaly is one of the rare forms of heriditary thrombocytopenia. Since fewer than 100 cases of May-Hegglin anomaly have been described to date, major controversies regarding the adequacy of hemostasis in vivo and abnormalities of platelet function in vitro continue to prevail. This report describes the...

journal_title：American journal of clinical pathology

authors： Hamilton RW,Shaikh BS,Ottie JN,Storch AE,Saleem A,White JG

更新日期：1980-11-01 00:00:00

abstract：:The authors describe an unusual variant of alkaline phosphatase (ALP) discovered in a patient with a 90-fold increase in serum ALP. The variant ALP was indistinguishable from the bone isoenzyme when subjected to chemical inhibition, heat inactivation, lectin precipitation, and routine electrophoresis. However, treatme...

journal_title：American journal of clinical pathology

authors： Schreiber WE,Gorecki T,Bernstein V

更新日期：1991-05-01 00:00:00

abstract：:"Chondroid chordoma" is a controversial and confusing entity that was originally described by Heffelfinger and colleagues as a biphasic malignant neoplasm possessing elements of both chordoma and cartilaginous tissue. Because the premise for this distinction was based strictly on histomorphologic criteria, the light m...

journal_title：American journal of clinical pathology

authors： Jeffrey PB,Biava CG,Davis RL

更新日期：1995-03-01 00:00:00

abstract：:Reducing the rate of avoidable errors is crucial to patient safety. Telephone calls with misunderstood critical results constitute one area in which opportunities for improvement exist. The aviation industry has dealt with this issue by requiring pilots to repeat instructions received from the air traffic controller. ...

journal_title：American journal of clinical pathology

authors： Barenfanger J,Sautter RL,Lang DL,Collins SM,Hacek DM,Peterson LR

更新日期：2004-06-01 00:00:00

abstract：:A variant hemoglobin fraction may be an incidental finding during HbA(1c) analysis using the G8 Tosoh HPLC analyzer, but it is unclear if the retention times and fraction patterns can reliably predict the findings of a high-performance liquid chromatography (HPLC) β-thalassemia program (Bio Rad Variant II analyzer). W...

journal_title：American journal of clinical pathology

authors： Froom P,Henig C,Zalman L,Barak M

更新日期：2012-09-01 00:00:00

abstract：:Thrombocytopenia frequently complicates neonatal necrotizing enterocolitis (NEC) and has been postulated to result from absorption of bacterial endotoxins from the injured gut. The authors tested blood obtained during 47 episodes of NEC for endotoxin-like activity (ELA), using a Limulus amoebocyte lysate assay and fou...

journal_title：American journal of clinical pathology

authors： Scheifele DW,Olsen EM,Pendray MR

更新日期：1985-02-01 00:00:00

abstract：:We report 2 cases of splenic postchemotherapy histiocyte-rich pseudotumor. Each patient had a history of diffuse large B-cell lymphoma, treated with multiagent chemotherapy. Computed tomography scans performed on both patients showed splenic masses. A positron emission tomography scan performed on 1 patient showed inc...

journal_title：American journal of clinical pathology

authors： Chandra P,Wen YH,Tuli S,Raphael BG,Amorosi EL,Medeiros LJ,Ibrahim S

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVES:A systematic review of the literature was performed to identify whether minimum formalin fixation time may be reduced for reliable immunohistochemical assessment of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). METHODS:PubMed, EMBASE, and the Cochra...

journal_title：American journal of clinical pathology

authors： Kalkman S,Barentsz MW,van Diest PJ

更新日期：2014-07-01 00:00:00

abstract：:In today's environment, many laboratories and pathology practices are challenged to maintain or increase their quality while simultaneously lowering their overall costs. The cost of improving specimen processes is related to quality, and we demonstrate that actual costs can be reduced by designing "quality at the sour...

journal_title：American journal of clinical pathology

authors： Carlson RO,Amirahmadi F,Hernandez JS

更新日期：2012-09-01 00:00:00

abstract：:Immunohistochemical study of smooth muscle myosin, a protein distinct from skeletal, cardiac, or nonmyogenous myosins in paraffin-embedded normal tissues and benign and malignant mesenchymal tumors revealed its strong expression in normal smooth muscle, capillary endothelium, and pericytes. All benign smooth muscle tu...

journal_title：American journal of clinical pathology

authors： Donner L,de Lanerolle P,Costa J

更新日期：1983-11-01 00:00:00

abstract：:The uptake and storage of 5-hydroxytryptamine by human platelets from normal donors and patients with the carcinoid syndrome are reported. When platelets were incubated in the presence of 3H-5-hydroxytryptamine (50 microM), an initial phase of rapid uptake was observed until 5-hydroxytryptamine levels of 1--2 microgra...

journal_title：American journal of clinical pathology

authors： Lewis JC,Moertel CG

更新日期：1978-10-01 00:00:00

abstract：:To increase transplantation access, particularly in living-donor renal transplantation, efforts have been made to overcome the barrier of ABO incompatibility. In adults, the most successful cases have involved renal transplantation. Although the overall goal of reducing antibodies against donor ABO before and after tr...

journal_title：American journal of clinical pathology

authors： Warner PR,Nester TA

更新日期：2006-06-01 00:00:00