An immunohistologic study of the feto-acinar pancreatic protein (FAP) in the normal pancreas, chronic pancreatitis, pancreatic adenocarcinoma, and intraabdominal metastases of adenocarcinomas.

abstract：:The authors describe the case of a 33-year-old man with a solitary cystic lesion of the left distal radius with central radiodensities that radiographically suggested a chondroid matrix. Curettage of the lesion revealed numerous calcospherites with a lamellar structure. This lamellar pattern is thought to be a result ...

journal_title：American journal of clinical pathology

authors： Kragel PJ,Williams J,Garvin DF,Goral AB

更新日期：1989-12-01 00:00:00

abstract：:Characteristically, mantle cell lymphoma (MCL) expresses surface immunoglobulin (sIg), CD19, CD20, and CD5 and lacks CD10 and CD23. Rare CD5-MCL variants have been described. This report describes a case of leukemic MCL with morphologically and immunophenotypically distinct classic MCL and blastoid-variant MCL (BV-MCL...

journal_title：American journal of clinical pathology

authors： Morice WG,Hodnefield JM,Kurtin PJ,Hanson CA

更新日期：2004-07-01 00:00:00

abstract：:We studied the beta-catenin immunohistochemical profile in tumors expressing shadow cells: pilomatricoma, 10 cases; calcifying odontogenic cyst, 6 cases; and craniopharyngioma, 9 cases. There was strong membranous, cytoplasmic, and nuclear staining of the immature basaloid cells in all of these tumors. Shadow cells we...

journal_title：American journal of clinical pathology

authors： Hassanein AM,Glanz SM,Kessler HP,Eskin TA,Liu C

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVES:BRAF V600E mutation is characteristic of hairy cell leukemia (HCL). A V600E mutation-specific antibody, VE1, has been recently developed. We studied the diagnostic utility of this antibody in HCL and compared it with other B-cell neoplasms. METHODS:VE1 activity was assessed using immunohistochemistry in 90 ...

journal_title：American journal of clinical pathology

authors： Uppal G,Ly V,Wang ZX,Bajaj R,Solomides CC,Banks PM,Medeiros LJ,Peiper SC,Gong JZ

更新日期：2015-01-01 00:00:00

abstract：:Blastomycosis generally results from inhalation of Blastomyces dermatitidis conidia following exposure to contaminated soil in an endemic area. Primary infections commonly involve the lungs, although secondary dissemination to other body sites may occur. We describe 2 cases of osseous blastomycosis in people living ou...

journal_title：American journal of clinical pathology

authors： Veligandla SR,Hinrichs SH,Rupp ME,Lien EA,Neff JR,Iwen PC

更新日期：2002-10-01 00:00:00

abstract：:We analyzed the diagnostic role of claudins in effusion cytology in 325 effusions, including 218 ovarian, 49 breast, 15 cervical or endometrial, 10 gastrointestinal, and 8 lung adenocarcinomas and 25 malignant mesotheliomas (MMs). Specimens were analyzed for claudin-1 and claudin-3 expression using immunohistochemical...

journal_title：American journal of clinical pathology

authors： Kleinberg L,Holth A,Fridman E,Schwartz I,Shih IeM,Davidson B

更新日期：2007-06-01 00:00:00

abstract：:The results obtained with eight pregnancy kits on 735 urines were compared. Overall accuracies were similar and fairly high (93.4 to 95.37%), although only 78.28% of all pregnancies were simultaneously detected by all eight kits. It is suggested that the different performances of each kit could be accounted for not on...

journal_title：American journal of clinical pathology

authors： Porres JM,D'Ambra C,Lord D,Garrity F

更新日期：1975-10-01 00:00:00

abstract：:In view of their reported reciprocal effects on apoptosis, the expression of p53 and bcl-2 proteins was studied in 46 cases of Hodgkin's disease by immunocytochemical labeling. We found p53 protein in Reed-Sternberg cells and their mononuclear variants in 16 of the 46 cases (34.7%) of Hodgkin's disease, mainly in a nu...

journal_title：American journal of clinical pathology

authors： Doussis IA,Pezzella F,Lane DP,Gatter KC,Mason DY

更新日期：1993-06-01 00:00:00

abstract：Objectives:Free light chain (FLC) measurement gained a lot of interest for diagnostic workup of monoclonal gammopathy. Methods:We evaluated the performance of turbidimetric polyclonal Freelite (The Binding Site, Birmingham, UK) assays on Cobas 6000 (Roche Diagnostics, Rotkreuz, Switzerland) and nephelometric monoclona...

journal_title：American journal of clinical pathology

authors： Messiaen AS,De Sloovere MMW,Claus PE,Vercammen M,Van Hoovels L,Heylen O,Debrabandere J,Vanpoucke H,De Smet D

更新日期：2017-06-01 00:00:00

abstract：:Anaplastic large cell lymphoma (ALCL) is recognized as 2 distinct diseases: anaplastic lymphoma kinase (ALK)+ ALCL and ALK- ALCL. ALK+ ALCL occurs in younger patients and has a better prognosis. Human T-cell lymphotropic virus (HTLV-1) is linked to the development of adult T-cell leukemia/lymphoma (ATLL), which freque...

journal_title：American journal of clinical pathology

authors： Gualco G,Chioato L,Weiss LM,Harrington WJ Jr,Bacchi CE

更新日期：2009-07-01 00:00:00

abstract：:Using Venn diagrams derived from set theory, a mathematic model is presented that allows triple-label immunophenotypic analysis of cells based upon double-label measurements. Practical applications of this method are illustrated and discussed. Using this model, triple-label data concerning Leu-8 and Leu-9 (CD7) antige...

journal_title：American journal of clinical pathology

authors： Wood GS

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVES:Meningiomas usually can be readily diagnosed on H&E alone, although occasionally immunohistochemistry (IHC) confirmation is desirable. Studies exploring the diagnostic utility of either podoplanin (D2-40) or E-cadherin IHC in meningiomas have conflicted, and no studies exist in which the two IHCs have been u...

journal_title：American journal of clinical pathology

authors： Mrachek EK,Davis D,Kleinschmidt-DeMasters BK

更新日期：2015-12-01 00:00:00

abstract：Objectives:The plasma-thrombin method is commonly used to make cell blocks from fine-needle aspiration (FNA) samples but requires centrifugation. We describe a modification to this method that does not require centrifugation for use in resource-limited settings. Methods:Pooled fresh plasma is aliquoted into 2-mL Eppen...

journal_title：American journal of clinical pathology

authors： Aisagbonhi O,Birungi A,Atwine R,Behayo P,Ayebaziwe B,Roberts D,Tambouret R

更新日期：2018-07-03 00:00:00

abstract：:Although Stat tests are one of the most important features of clinical laboratory performance, the indexed literature is devoid of significant discussion of the subject. The authors, undertook a study by querying hospital laboratories about their current practices and received 38 useable answers dealing with the types...

journal_title：American journal of clinical pathology

authors： Barnett RN,McIver DD,Gorton WL

更新日期：1978-05-01 00:00:00

abstract：:The use of direct thrombin inhibitors (DTIs) for prophylactic or therapeutic anticoagulation is increasing because of the predictable bioavailability and short half-life of these DTIs. However, in certain situations, indication of the concentration is warranted. We investigated the effects of 3 DTIs (lepirudin, argatr...

journal_title：American journal of clinical pathology

authors： Curvers J,van de Kerkhof D,Stroobants AK,van den Dool EJ,Scharnhorst V

更新日期：2012-10-01 00:00:00

abstract：:Recent studies in Western populations have shown that trisomy 3 is the most frequent chromosomal abnormality in primary gastric lymphoma (PGL). To study the incidence of trisomy 3 and its implications for the pathogenesis of PGL in Hong Kong, we have applied the technique of chromosome in situ hybridization in 13 case...

journal_title：American journal of clinical pathology

authors： Zhang Y,Cheung AN,Chan AC,Shen DH,Xu WS,Chung LP,Ho FC

更新日期：1998-09-01 00:00:00

abstract：:Determination of breast cancer estrogen receptor (ER) status as a predictor of tumor response to adjuvant endocrine therapy remains a mainstay of breast cancer management. Recent second generation anti-ER antibodies and new epitope retrieval methods have produced paraffin-based immunohistochemical results that correla...

journal_title：American journal of clinical pathology

authors： Nichols GE,Frierson HF Jr,Boyd JC,Hanigan MH

更新日期：1996-09-01 00:00:00

abstract：:A 75-year-old man with Staphylococcus aureus endocarditis in whom acute diffuse proliferative glomerulonephritis developed is described. The light- and electron-microscopic changes of the glomeruli in this case were identical to those of acute poststreptococcal glomerulonephritis. Immunofluorescence revealed depositio...

journal_title：American journal of clinical pathology

authors： Yum M,Wheat LJ,Maxwell D,Edwards JL

更新日期：1978-11-01 00:00:00

abstract：:The significance of the human immunodeficiency virus (HIV) in the small intestinal lamina propria in patients with the acquired immune deficiency syndrome or conditions related to that syndrome who have chronic diarrhea and malabsorption is unclear. To investigate this issue, upper endoscopy (after a 12- to 16-hour fa...

journal_title：American journal of clinical pathology

authors： Ehrenpreis ED,Patterson BK,Brainer JA,Yokoo H,Rademaker AW,Glogowski W,Noskin GA,Craig RM

更新日期：1992-01-01 00:00:00

abstract：:In normal subjects, mean platelet volume (MPV) has an inverse, nonlinear relation with platelet count, while platelet volume heterogeneity has a direct, nonlinear relation with MPV. Compared with the reference range established for normal subjects, patients with chronic lymphocytic leukemia, atherosclerotic heart dise...

journal_title：American journal of clinical pathology

authors： Bessman JD,Williams LJ,Gilmer PR Jr

更新日期：1982-08-01 00:00:00

abstract：:In order to determine the significance of 40% or more leukemic cells in hand-mirror configuration in the bone marrow (hand-mirror cell leukemia), eight of 34 cases of acute lymphoblastic leukemia and one of 17 cases of acute myeloblastic leukemia were collected from a six-year period. Five of the eight patients who ha...

journal_title：American journal of clinical pathology

authors： Glassy EF,Sun NC,Okun DB

更新日期：1980-11-01 00:00:00

abstract：:Although acute myeloid leukemias (AMLs) cytochemically negative for myeloperoxidase are now well recognized, myeloid surface antigen-negative AMLs are rare. The morphologic, cytochemical, immunologic, and cytogenetic or molecular features of such cases are described in four adults aged 19 to 60 years. All had AML with...

journal_title：American journal of clinical pathology

authors： Arber DA,Glackin C,Lowe G,Medeiros LJ,Slovak ML

更新日期：1997-01-01 00:00:00

abstract：:In a case of secondary syphilis with gastric involvement, the clinical history and roentgenographic and gastroscopic examiniations initially suggested an infiltrative malignant neoplasm. However, macroscopic and histologic examination of the partial gastrectomy specimen demonstrated an erosive, inflammatory lesion. Su...

journal_title：American journal of clinical pathology

authors： Butz WC,Watts JC,Rosales-Wuintana S,Hicklin MD

更新日期：1975-06-01 00:00:00

abstract：:Percent-free prostate-specific antigen (proportion of free prostate-specific antigen [PSA] to total PSA) has been shown recently in studies on frozen serum samples to be more useful than total PSA alone in distinguishing prostate cancer from benign conditions of the prostate gland. The primary purpose of our study was...

journal_title：American journal of clinical pathology

authors： Henricks WH,England BG,Giacherio DA,Oesterling JE,Wojno KJ

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVES:To describe consecutive vulvar biopsy cases and to create an educational template for pathology trainees and practicing pathologists. METHODS:We reviewed 189 consecutive biopsies from the female genital area skin and mucosa. We classified them based on etiologies and examined limited clinical information. ...

journal_title：American journal of clinical pathology

authors： Joehlin-Price AS,Mully TW

更新日期：2020-09-11 00:00:00

abstract：:Campylobacter medium (CAMPY, Becton Dickinson [BD] Microbiology Systems, Cockeysville, MD) and Vancomycin Screen Agar (VSA, BD) were compared for their ability to screen for vancomycin-resistant Enterococcus (VRE) from primary plates. A microdilution minimal inhibitory concentration (MIC) assay (Pasco, BD) served as t...

journal_title：American journal of clinical pathology

authors： Shigei J,Tan G,Shiao A,de la Maza LM,Peterson EM

更新日期：2002-01-01 00:00:00

abstract：:Vimentin has been regarded as the intermediate filament characteristic of normal and neoplastic mesenchymal cells and keratins as typical of epithelial cells and the neoplasms derived from them. However, many epithelial cells in tissue culture or in effusion, as well as cells in some solid epithelial neoplasms such as...

journal_title：American journal of clinical pathology

authors： Azumi N,Battifora H

更新日期：1987-09-01 00:00:00

abstract：:Double immunostaining of tissue sections by monoclonal antibodies has been performed using, in immunofluorescence, combinations of reagents conjugated with different fluorochromes. These were monoclonal antibodies directly labeled with phycoerythrin (a new red fluorochrome) and haptenated monoclonal antibodies detecte...

journal_title：American journal of clinical pathology

authors： Pizzolo G,Chilosi M

更新日期：1984-07-01 00:00:00

abstract：OBJECTIVES:Timely reporting of immunosuppressant (ISP) drug level results is needed for transplant patient management. This study characterized the local ISP testing process, identified bottlenecks and implemented process improvements to meet turnaround time requirements. METHODS:Laboratory information time stamps, di...

journal_title：American journal of clinical pathology

authors： Barakauskas VE,Bradshaw TA,Smith LD,Lehman CM,Johnson-Davis KL

更新日期：2016-08-01 00:00:00

abstract：:Anti-glomerular basement membrane (anti-GBM) glomerulonephritis is a rare disease caused by IgG autoantibodies against the glomerular basement membrane. We describe clinical and pathologic findings in a series of renal biopsy specimens from 80 patients. The patients ranged in age from 16 to 87 years. The age distribut...

journal_title：American journal of clinical pathology

authors： Fischer EG,Lager DJ

更新日期：2006-03-01 00:00:00