A Venn diagram model that allows triple-label immunophenotypic analysis of cells based upon double-label measurements.

abstract：OBJECTIVES:Overuse of laboratory tests is a persistent issue. We examined the use and overuse of serum immunofixation electrophoresis and serum free light chain assays to develop an algorithm for optimizing utilization. METHODS:A retrospective review of all tests, for investigation of monoclonal gammopathies, for all ...

journal_title：American journal of clinical pathology

authors： Heaton C,Vyas SG,Singh G

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:The metaplastic intestinal epithelium in Barrett esophagus (BE) occasionally contains Paneth cells; however, little is known regarding the prevalence and significance of Paneth cell metaplasia (PCM) in BE. METHODS:We evaluated 757 esophageal biopsy specimens with intestinal metaplasia (IM) for PCM. Outcome ...

journal_title：American journal of clinical pathology

authors： Chen W,Frankel WL,Cronley KM,Yu L,Zhou X,Yearsley MM

更新日期：2015-05-01 00:00:00

abstract：:The authors evaluated the Yellow IRIS automated urinalysis instrument (International Remote Imaging Systems, Chatsworth, CA 91311) in terms of its analytic performance as well as its ease of use. The Yellow IRIS is a system using automated intelligence microscopy (AIM), coupled with a dipstick reader and specific grav...

journal_title：American journal of clinical pathology

authors： Roe CE,Carlson DA,Daigneault RW,Statland BE

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVES:To describe the histopathologic and immunophenotypic features of a temporary splenic allograft exposed to massive donor-specific antibody (DSA) insult. METHODS:A human cadaveric donor splenic allograft was temporarily transplanted in a highly sensitized patient with the intention of removing DSA before inte...

journal_title：American journal of clinical pathology

authors： Gaitonde S,Hassan M,Mehta V,Benedetti E,Tzvetanov I,Lichvar A,Pirzada S,Setty S

更新日期：2020-11-21 00:00:00

abstract：:The objective of the study was to evaluate the current standard practice of using volume and total nucleated cell (TNC) count for the selection of cord blood (CB) units for cryopreservation and further transplantation. Data on 794 CB units whose CD34+ cell content was determined by flow cytometry were analyzed by usin...

journal_title：American journal of clinical pathology

authors： Jaime-Pérez JC,Monreal-Robles R,Rodríguez-Romo LN,Mancías-Guerra C,Herrera-Garza JL,Gómez-Almaguer D

更新日期：2011-11-01 00:00:00

abstract：:To compare the Affirm VPIII molecular test (Becton Dickinson, Burlington, NC) with morphologic identification used in routine Papanicolaou (Pap) test screening in the detection and identification of Candida species, Trichomonas vaginalis, and Gardnerella vaginalis, we identified 431 cases with a concomitant Pap test a...

journal_title：American journal of clinical pathology

authors： Levi AW,Harigopal M,Hui P,Schofield K,Chhieng DC

更新日期：2011-03-01 00:00:00

abstract：:The measurement of beta-thromboglobulin (BTG) and platelet lactic dehydrogenase (LDH) as markers for alpha-granule release and platelet lysis, respectively, has been reported to correlate with the amount of damage incurred during the preparation and storage of platelet concentrates. We compared the concentrations of t...

journal_title：American journal of clinical pathology

authors： Kalmin ND,Wilson MJ,Liles BA

更新日期：1983-06-01 00:00:00

abstract：:Examination of kidneys of ten patients with uremia and severe hypertension treated by chronic intermittent hemodialysis revealed a deposition of glycogen within interstitial cells of the renal medulla. This is unlike any described renal distribution of glycogen. Electron microscopic studies performed in one case demon...

journal_title：American journal of clinical pathology

authors： Hughson MD,McManus JF,Fitts CT,Williams AV

更新日期：1979-09-01 00:00:00

abstract：:Peripheral blood samples of 23 patients who had hairy cell leukemia were examined for leukocyte alkaline phosphatase scores. Leukocyte alkaline phosphatase levels were elevated in seventeen patients (74%), were normal in six (26%), and were not decreased in any patient. The mean leukocyte alkaline phosphatase score wa...

journal_title：American journal of clinical pathology

authors： Aiba M,Raffa PP,Katayama I

更新日期：1980-09-01 00:00:00

abstract：:To study the histogenesis of and determine the most useful markers for diagnosing anaplastic thyroid carcinoma (ATC), 32 cases, including 2 with numerous osteoclast-like cells, were stained with a battery of antibodies to epithelial (keratin, epithelial membrane antigen [EMA], carcinoembryonic antigen [CEA]), mesenchy...

journal_title：American journal of clinical pathology

authors： Ordóñez NG,El-Naggar AK,Hickey RC,Samaan NA

更新日期：1991-07-01 00:00:00

abstract：:The significance of the human immunodeficiency virus (HIV) in the small intestinal lamina propria in patients with the acquired immune deficiency syndrome or conditions related to that syndrome who have chronic diarrhea and malabsorption is unclear. To investigate this issue, upper endoscopy (after a 12- to 16-hour fa...

journal_title：American journal of clinical pathology

authors： Ehrenpreis ED,Patterson BK,Brainer JA,Yokoo H,Rademaker AW,Glogowski W,Noskin GA,Craig RM

更新日期：1992-01-01 00:00:00

abstract：:Immunohistochemical study of smooth muscle myosin, a protein distinct from skeletal, cardiac, or nonmyogenous myosins in paraffin-embedded normal tissues and benign and malignant mesenchymal tumors revealed its strong expression in normal smooth muscle, capillary endothelium, and pericytes. All benign smooth muscle tu...

journal_title：American journal of clinical pathology

authors： Donner L,de Lanerolle P,Costa J

更新日期：1983-11-01 00:00:00

abstract：:Immunophenotypic analysis of acute leukemias is time consuming and often requires flow cytometric analysis. A 1-hour alkaline phosphatase-labeled streptavidin-biotin immunocytochemical procedure was evaluated as an alternative. Seventeen cases of acute leukemia, including 10 acute lymphocytic (ALL) and 7 acute nonlymp...

journal_title：American journal of clinical pathology

authors： Hammer RD,Collins RD,Ebrahimi S,Casey TT

更新日期：1992-06-01 00:00:00

abstract：:The development of sensitive immunofluorescent technics for the detection of platelet antibodies has stimulated renewed interest in the field of platelet immunology. However, the analysis of multispecific sera containing both HLA and platelet-specific antibodies requires cumbersome absorption technics and relatively l...

journal_title：American journal of clinical pathology

authors： Boisvert A,MacPherson BR

更新日期：1983-12-01 00:00:00

abstract：:We performed a retrospective clinicopathologic study on sequential biopsy specimens from 90 patients with Philadelphia chromosome-positive chronic myelogenous leukemia to study therapy-specific effects of busulfan (28 patients), hydroxyurea (32 patients), and interferon-alfa (IFN-alfa; 30 patients). Bone marrow specim...

journal_title：American journal of clinical pathology

authors： Thiele J,Kvasnicka HM,Schmitt-Graeff A,Bundschuh S,Biermann T,Roessler G,Wasmus M,Diehl V,Zankovich R,Schaefer HE

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVES:To investigate the clinicopathologic features of extranodal natural killer/T-cell lymphoma (ENKTL) not preceded by another Epstein-Barr virus (EBV)-related disorder in children and adolescents. METHODS:A series of 17 cases of ENKTL not preceded by another EBV-related disorder in children and adolescents in ...

journal_title：American journal of clinical pathology

authors： Huang Y,Xie J,Ding Y,Zhou X

更新日期：2016-01-01 00:00:00

abstract：:A new disposable bleeding time device (Hemalet) was tested in 20 normal individuals and 11 patients with various bleeding disorders. The results were compared with those of Simplate II. The mean bleeding time for normal individuals was 5.4 +/- 1.5 (mean +/- 1 SD) minutes by Hemalet and 5.8 +/- 1.4 (mean +/- 1 SD) minu...

journal_title：American journal of clinical pathology

authors： Toomey KC,Kim HC,Kosmin M,Saidi P

更新日期：1986-05-01 00:00:00

abstract：:Human papillomavirus (HPV) testing is more sensitive for the detection of cervical precancer and cancer than cervical cytology. The increased sensitivity of HPV testing and cytology combined ("cotesting") compared to cytology alone permitted professional societies to recommend 3-year screening intervals among the cote...

journal_title：American journal of clinical pathology

authors： Kinney W,Stoler MH,Castle PE

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVES:To investigate metastasis associated in colon cancer 1 (MACC1) and MET expression in colorectal adenoma, Tis, early-stage invasive (T1 and T2), and advanced adenocarcinoma with liver metastasis using immunohistochemistry. METHODS:Ninety-three paraffin-embedded colorectal tumor specimens were immunohistochem...

journal_title：American journal of clinical pathology

authors： Ren B,Zakharov V,Yang Q,McMahon L,Yu J,Cao W

更新日期：2013-11-01 00:00:00

abstract：:Anti-glomerular basement membrane (anti-GBM) glomerulonephritis is a rare disease caused by IgG autoantibodies against the glomerular basement membrane. We describe clinical and pathologic findings in a series of renal biopsy specimens from 80 patients. The patients ranged in age from 16 to 87 years. The age distribut...

journal_title：American journal of clinical pathology

authors： Fischer EG,Lager DJ

更新日期：2006-03-01 00:00:00

abstract：:A teenage male, with Goodpasture's syndrome and serum antiglomerular basement membrane (anti-GBM) antibodies, had a focal proliferative glomerulonephritis with crescents. Immunofluorescence microscopy of his glomeruli using anti-IgG antibodies demonstrated both intense linear GBM staining, and granular subepithelial s...

journal_title：American journal of clinical pathology

authors： Jennette JC,Lamanna RW,Burnette JP,Wilkman AS,Iskander SS

更新日期：1982-09-01 00:00:00

abstract：OBJECTIVES:Assess support for the effectiveness of two separate practices, restrictive transfusion strategy and computerized physician order entry/clinical decision support (CPOE/CDS) tools, in decreasing RBC transfusions in adult surgical and nonsurgical patients. METHODS:Following the Centers for Disease Control and...

journal_title：American journal of clinical pathology

authors： Derzon JH,Clarke N,Alford A,Gross I,Shander A,Thurer R

更新日期：2019-10-07 00:00:00

abstract：:A tumor of the larynx composed of a small infiltrating and well-differentiated squamous cell carcinoma and a large polypoid sarcomatous mass showing the histologic features of the malignant giant cell tumor of soft parts (MGCT) is reported. Other types of sarcomatous components have been described with squamous cell c...

journal_title：American journal of clinical pathology

authors： Alguacil-Garcia A,Alonso A,Pettigrew NM

更新日期：1984-09-01 00:00:00

abstract：:The authors studied the performance of four measures of laboratory turnaround time: the mean, median, 90th percentile, and proportion of tests reported within a predetermined cut-off interval (proportion of acceptable tests [PAT]). Measures were examined with the use of turnaround time data from 11,070 stat partial th...

journal_title：American journal of clinical pathology

authors： Valenstein PN,Emancipator K

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVES:Promotion of high-quality care at a lower cost requires educational initiatives across the continuum of medical education. A needs assessment was performed to inform the design of an educational tool with the goal of teaching laboratory stewardship to medical students. METHODS:The needs assessment consisted...

journal_title：American journal of clinical pathology

authors： Roth CG,Huang WY,Caruso AC,Sekhon N,Kung DH,Greely JT,Du YB,Holder-Haynes JG,Little JE,Fielder EK,Ismail NJ

更新日期：2020-01-01 00:00:00

abstract：:An evaluation of the validity in infants of standard computations for the correction of white cell counts in blood-contaminated cerebrospinal fluid (traumatic lumbar puncture) was undertaken. In 39 infants with significant blood contamination (greater than 10(4) red blood cells/microL) and no evidence of bacterial men...

journal_title：American journal of clinical pathology

authors： Novak RW

更新日期：1984-07-01 00:00:00

abstract：:One hundred fifty-two patients with amyloid in the tenosynovium who had carpal tunnel release were identified. Twenty-eight patients were excluded because of systemic amyloidosis: primary systemic amyloidosis (AL) in 24, secondary amyloidosis (AA) in 3, and familial amyloidosis (AF) in 1. The remaining 124 patients (8...

journal_title：American journal of clinical pathology

authors： Kyle RA,Eilers SG,Linscheid RL,Gaffey TA

更新日期：1989-04-01 00:00:00

abstract：:A multiplex polymerase chain reaction (PCR) assay using oligonucleotide primers to detect mecA and 16S ribosomal RNA gene was developed to aid in identification of methicillin-resistant staphylococci. Validation included 99 isolates of staphylococcus grouped into one of five categories: methicillin-susceptible coagula...

journal_title：American journal of clinical pathology

authors： Salisbury SM,Sabatini LM,Spiegel CA

更新日期：1997-03-01 00:00:00

abstract：:A 61-year-old man with acquired immunodeficiency syndrome (AIDS) sought care because of the onset of progressive dysphagia. He was found to have a perforated, fungating esophageal mass. The combined histologic and immunologic findings were diagnostic of Hodgkin's disease, nodular sclerosis type, lymphocyte-depleted va...

journal_title：American journal of clinical pathology

authors： Gelb AB,Medeiros LJ,Chen YY,Weiss LM,Weidner N

更新日期：1997-11-01 00:00:00

abstract：:Sera have been submitted to the authors' laboratory for syphilis testing at a dramatically increased rate since the start of the human immunodeficiency virus type 1 epidemic. Thus they were interested in evaluating a new enzyme immunoassay, the DCL Syphilis-G test kit (DCL-G, Diagnostic Chemicals Ltd., Oxford, CT) for...

journal_title：American journal of clinical pathology

authors： Nayar R,Campos JM

更新日期：1993-03-01 00:00:00