Studies of end-stage kidneys. III. Glycogen deposition in interstitial cells of the renal medulla.

Abstract:

:Examination of kidneys of ten patients with uremia and severe hypertension treated by chronic intermittent hemodialysis revealed a deposition of glycogen within interstitial cells of the renal medulla. This is unlike any described renal distribution of glycogen. Electron microscopic studies performed in one case demonstrated monoparticulate glycogen both diffuse in the interstitial cell cytoplasm and locally aggregated beside lipid droplets. The findings provide evidence for a metabolic abnormality of renal medullary interstitial cells in patients who have protracted uremia.

journal_name

Am J Clin Pathol

authors

Hughson MD,McManus JF,Fitts CT,Williams AV

doi

10.1093/ajcp/72.3.400

subject

Has Abstract

pub_date

1979-09-01 00:00:00

pages

400-4

issue

3

eissn

0002-9173

issn

1943-7722

journal_volume

72

pub_type

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