The equivocally amplified HER2 FISH result on breast core biopsy: indications for further sampling do affect patient management.

abstract：OBJECTIVES:To differentiate the leprosy agents Mycobacterium leprae and Mycobacterium lepromatosis and correlate them with geographic distribution and clinicopathologic features. METHODS:Species-specific polymerase chain reactions were used to detect each bacillus in archived skin biopsy specimens from patients with l...

journal_title：American journal of clinical pathology

authors： Han XY,Aung FM,Choon SE,Werner B

更新日期：2014-10-01 00:00:00

abstract：:This investigation was designed to improve reference information and to evaluate the influences of sample distribution and age on the derived reference intervals. Specimens from 127 men were collected after a 12- to 14-hour fast and analyzed by 60 different laboratory procedures. Differences in the reference intervals...

journal_title：American journal of clinical pathology

authors： Ash KO,Clark SJ,Sandberg LB,Hunter E,Woodward SC

更新日期：1983-05-01 00:00:00

abstract：:A number of variables thought to affect measurement of prothrombin time (PT) and partial thromboplastin time (PTT) were examined in an effort to determine more precisely their effects on these measurements. On the basis of these studies, it is proposed that blood specimens be anticoagulated with one part 3.8% (w./v.) ...

journal_title：American journal of clinical pathology

authors： Koepke JA,Rodgers JL,Ollivier MJ

更新日期：1975-11-01 00:00:00

abstract：:The clinical microscopy (fluids) laboratory evaluates almost every body fluid that is obtained in the hospital. Because the fluids laboratory functions at all hours, it is often the first laboratory to receive a body fluid. In addition to its primary purpose of quantitating categories of cells, the medical technologis...

journal_title：American journal of clinical pathology

authors： Ben-Ezra J,Stastny JF,Harris AC,Bork L,Frable WJ

更新日期：1994-10-01 00:00:00

abstract：:The authors describe two patients with clinically and histopathologically documented advanced (tumor) stage mycosis fungoides. In each case the large, pleomorphic neoplastic cells lacked the monoclonal antibody-defined cell surface antigens commonly associated with immature and mature T-cells, i.e., T11, Leu-1, T3, T4...

journal_title：American journal of clinical pathology

authors： Wieczorek R,Suhrland M,Ramsay D,Reed ML,Knowles DM 2nd

更新日期：1986-07-01 00:00:00

abstract：:Labor use ratings assigned to instruments by the Workload Recording Method (WRM) do not change with batch size or walk-away time use. The authors evaluated the effect of both on the labor use of the analyzers Paramax B6100 (Baxter Paramax, Irvine, CA) and Ektachem 700 (Eastman Kodak, Rochester, NY) by timing all worke...

journal_title：American journal of clinical pathology

authors： McClellan GA,Nipper HC,Horn MJ,Burris WD,Hodges K,Monaco S,Cox RS Jr

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVES:Bladder cancers invading the muscularis mucosae (MM) are treated differently from those invading the muscularis propria (MP). However, it may be difficult to determine the type of smooth muscle in transurethral resection (TUR) or biopsy specimens. We aimed to investigate the clinicopathologic features of bla...

journal_title：American journal of clinical pathology

authors： Hwang MJ,Kamat AM,Dinney CP,Czerniak B,Guo CC

更新日期：2020-07-07 00:00:00

abstract：:Cultures from the gallbladder and blood of a 60-year-old man with acute cholecystitis grew Haemophilus aphrophilus. This organism, an unusual isolate in clinical specimens, is most frequently seen in patients with either endocarditis or brain abscesses. Haemophilus aphrophilus may be distinguished from Eikenella corro...

journal_title：American journal of clinical pathology

authors： Huck W,Britt MR

更新日期：1978-03-01 00:00:00

abstract：:Although some studies have examined the expression of aberrant markers such as CD2, CD7, CD10, CD13, CD33, and CD34 on B cells in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), a uniform multiparametric analysis of the frequency of expression of these markers using stringent criteria is lacking. By...

journal_title：American journal of clinical pathology

authors： Kampalath B,Barcos MP,Stewart C

更新日期：2003-06-01 00:00:00

abstract：:The Auto Microbic System (AMS) is an almost completely automated system, capable of identifying Enterobacteriaceae after 8 hours, and some glucose nonfermenters after 13 hours of incubation. The Autobac ID system is a mechanized, computer-assisted system capable of identifying Enterobacteriaceae and many nonfermentati...

journal_title：American journal of clinical pathology

authors： Barry AL,Gavan TL,Badal RE,Telenson MJ

更新日期：1982-10-01 00:00:00

abstract：OBJECTIVES:Myeloid and lymphoid neoplasms with abnormalities of fibroblast growth factor receptor 1 gene (FGFR1) are a rare and aggressive disease group that harbors translocations of FGFR1 with at least 14 recognized partner genes. We report a case of a patient with a novel t(17;21)(p13;q22) with RUNX1 rearrangement a...

journal_title：American journal of clinical pathology

authors： Kumar KR,Chen W,Koduru PR,Luu HS

更新日期：2015-05-01 00:00:00

abstract：:Posttransplantation lymphoproliferative disorders (PT-LPDs) occurring in T-cell depleted (TCD) allogeneic bone marrow transplant recipients seem to be different from those that arise in solid organ recipients in their early development, the high incidence of extensive dissemination at presentation, and their aggressiv...

journal_title：American journal of clinical pathology

authors： Orazi A,Hromas RA,Neiman RS,Greiner TC,Lee CH,Rubin L,Haskins S,Heerema NA,Gharpure V,Abonour R,Srour EF,Cornetta K

更新日期：1997-04-01 00:00:00

abstract：:The authors illustrate two neoplasms arising in the pretibial soft tissue that are histologically identical to adamantinoma of the long bones. The tumors developed in a 24-year-old woman and a 31-year-old man. Both were treated by local excision. Histologically, one tumor had a tubular pattern and one was composed of ...

journal_title：American journal of clinical pathology

authors： Mills SE,Rosai J

更新日期：1985-01-01 00:00:00

abstract：:The clonality of dendritic cell proliferations arising in patients with previously diagnosed B-cell non-Hodgkin lymphoma has not been determined. The highly polymorphic human androgen receptor gene (HUMARA) can be used to assess the pattern of X-chromosome inactivation and, hence, the clonality of tumors in female pat...

journal_title：American journal of clinical pathology

authors： Wu CD,Wickert RS,Williamson JE,Sun NC,Brynes RK,Chan WC

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVES:Pathogenic free-living amebae (FLAs) cause skin, ocular, and central nervous system (CNS) infections with significant morbidity and mortality. Diagnosis of FLA infections by pathologic examination of tissue sections can be aided using molecular assays. This study investigated the performance characteristics ...

journal_title：American journal of clinical pathology

authors： Norgan AP,Sloan LM,Pritt BS

更新日期：2019-11-04 00:00:00

abstract：:Pulmonary alveolar proteinosis (PAP) is an uncommon disease in which alveoli are progressively filled with surfactant-related material. Although a definitive diagnosis is usually made by an open lung biopsy, bronchoalveolar lavage (BAL) cytology may play a decisive role in the clinical work-up of these patients, and, ...

journal_title：American journal of clinical pathology

authors： Burkhalter A,Silverman JF,Hopkins MB 3rd,Geisinger KR

更新日期：1996-10-01 00:00:00

abstract：:Acute toxic hepatic necrosis is common and may be fatal. Predicting clinical outcome may be aided by following serum markers that could indicate recovery or may signify massive (substantial) destruction of functional liver mass. Previously, in a published case of chloroform poisoning, we serially assayed serum biomark...

journal_title：American journal of clinical pathology

authors： Horn KD,Wax P,Schneider SM,Martin TG,Nine JS,Moraca MA,Virji MA,Aronica PA,Rao KN

更新日期：1999-09-01 00:00:00

abstract：:A case is presented of an anterior mediastinal mass arising in a 64-year-old woman that showed on histologic, immunopathologic, and ultra-structural examination features of a poorly differentiated (insular) thyroid carcinoma. The tumor in this patient most likely arose from ectopically displaced thyroid tissue on the ...

journal_title：American journal of clinical pathology

authors： Dominguez-Malagon H,Guerrero-Medrano J,Suster S

更新日期：1995-10-01 00:00:00

abstract：:Whipple disease is a rare, chronic multisystem disease associated with the recently characterized organism Tropheryma whippelii. Extraintestinal manifestation involving the central nervous system, heart, and joints occasionally occurs. Involvement of the abdominal lymph nodes, especially the mesenteric and periaortic ...

journal_title：American journal of clinical pathology

authors： Alkan S,Beals TF,Schnitzer B

更新日期：2001-12-01 00:00:00

abstract：:The significance of the human immunodeficiency virus (HIV) in the small intestinal lamina propria in patients with the acquired immune deficiency syndrome or conditions related to that syndrome who have chronic diarrhea and malabsorption is unclear. To investigate this issue, upper endoscopy (after a 12- to 16-hour fa...

journal_title：American journal of clinical pathology

authors： Ehrenpreis ED,Patterson BK,Brainer JA,Yokoo H,Rademaker AW,Glogowski W,Noskin GA,Craig RM

更新日期：1992-01-01 00:00:00

abstract：:Inherited giant platelet disorders are extremely rare. The aim of this article is to review the clinical and laboratory features of this heterogeneous group and to arrive at a working classification. We conducted our literature search using the National Library of Medicine database. A total of 12 clinical entities wer...

journal_title：American journal of clinical pathology

authors： Mhawech P,Saleem A

更新日期：2000-02-01 00:00:00

abstract：:Histiocytosis-X cells were obtained at autopsy from the lungs and lymph nodes of a patient who died of the disseminated infantile form of this disease (Letterer-Siwe disease). The ability of these cells to synthesize and release prostaglandins was investigated in culture, by prelabeling the cell lipids with [14C] arac...

journal_title：American journal of clinical pathology

authors： Gonzalez-Crussi F,Hsueh W,Wiederhold MD

更新日期：1981-02-01 00:00:00

abstract：:Pseudomonas alcaligenes is a common soil and water inhabitant that has rarely been proven a human pathogen. We describe a fatal case of Pseudomonas alcaligenes endocarditis. The need for accurate identification of unusual organisms isolated in a clinical setting are discussed. ...

journal_title：American journal of clinical pathology

authors： Valenstein P,Bardy GH,Cox CC,Zwadyk P

更新日期：1983-02-01 00:00:00

abstract：:Myofibromatosis generally is regarded as a fibrous proliferative disease of neonates and children that, even when multicentric, has an excellent prognosis and a propensity for spontaneous involution. Reported is a case of solitary, locally recurrent myofibromatosis in the ear canal of an adult patient. It was initiall...

journal_title：American journal of clinical pathology

authors： Hogan SF,Salassa JR

更新日期：1992-06-01 00:00:00

abstract：:The major histocompatibility complex probably plays a crucial role in the efficacy of the cellular immune response against virally infected cervical diseases. Therefore, the allele-specific histocompatibility-related leukocyte antigens (HLA) class I and II expression on normal (n = 10), premalignant (n = 25), and mali...

journal_title：American journal of clinical pathology

authors： Hilders CG,Houbiers JG,Krul EJ,Fleuren GJ

更新日期：1994-01-01 00:00:00

abstract：:The authors tested a newly-developed computerized laser scanning cytometer (LSC) as a means of performing immunophenotypic analysis of hematologic specimens within their community hospital. Results were compared on a case-by-case basis with parallel flow cytometric and immunohistochemical data. A total of 71 specimens...

journal_title：American journal of clinical pathology

authors： Clatch RJ,Walloch JL,Zutter MM,Kamentsky LA

更新日期：1996-06-01 00:00:00

abstract：:Hairy cell populations of greater than 90 purity were prepared from six samples obtained from four patients with leukemic reticuloendotheliosis (LRE). These then were analyzed for surface immunoglobulin (SIg) and antigens specified by a panel of monoclonal antibodies. The hairy cells from all patients displayed SIg an...

journal_title：American journal of clinical pathology

authors： Janckila AJ,Stelzer GT,Wallace JH,Yam LT

更新日期：1983-04-01 00:00:00

abstract：:The ongoing collaborative relationship between a pathology department and the vendor of its laboratory information system is vitally important because of the strategic importance of the laboratory information system in managing the information product of the department. Laboratory information system vendors are value-...

journal_title：American journal of clinical pathology

authors： Friedman BA,Mitchell W

更新日期：1992-03-01 00:00:00

abstract：:We sought to characterize how well computerized "case flags" performed in evaluating critical diagnoses in anatomic pathology. All cases identified by a pathologist at sign-out and flagged as a critical diagnosis in anatomic pathology in 2 hospital laboratories during a 3-year period were reviewed. A subset of all cri...

journal_title：American journal of clinical pathology

authors： Renshaw A,Gould EW

更新日期：2012-03-01 00:00:00

abstract：:The finding of monoclonal B-cell lymphocytosis (MBL) raises questions on the nature of clonal cell expansion and its risk of progression. We identified and characterized 7 cases of clinically benign clonal B-cell lymphocytosis. The clonal lymphocytes were clearly of CD5- and non-chronic lymphocytic leukemia (CLL) phen...

journal_title：American journal of clinical pathology

authors： Amato D,Oscier DG,Davis Z,Mould S,Zheng J,Kolomietz E,Wang C

更新日期：2007-08-01 00:00:00