Abstract:
:A case is presented of an anterior mediastinal mass arising in a 64-year-old woman that showed on histologic, immunopathologic, and ultra-structural examination features of a poorly differentiated (insular) thyroid carcinoma. The tumor in this patient most likely arose from ectopically displaced thyroid tissue on the basis of a developmental defect. The clinicopathologic features and differential diagnosis of the lesion in the setting of its mediastinal location are discussed. Ectopic poorly differentiated (insular) carcinoma of the thyroid should be added to the list of mediastinal tumors showing a solid or insular growth pattern.
journal_name
Am J Clin Patholjournal_title
American journal of clinical pathologyauthors
Dominguez-Malagon H,Guerrero-Medrano J,Suster Sdoi
10.1093/ajcp/104.4.408subject
Has Abstractpub_date
1995-10-01 00:00:00pages
408-12issue
4eissn
0002-9173issn
1943-7722journal_volume
104pub_type
杂志文章abstract::Terminal deoxynucleotidyl transferase (TdT) is a marker of lymphoblastic disorders. Previously, the technique for determining TdT on smears was by indirect immunofluorescence. An immunoperoxidase procedure for detecting TdT on smears is reported. Results are in a comparable range with the indirect immunofluorescent te...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/77.2.174
更新日期:1982-02-01 00:00:00
abstract:OBJECTIVES:To explore the survival and definition of stage IA mixed endometrial carcinoma. METHODS:From June 1, 2010, to June 1, 2017, cases with stage IA endometrial cancer were included in this study. The survival outcomes were compared among patients with endometrioid (group A), nonendometrioid (group B), and mixed...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/aqz083
更新日期:2019-10-07 00:00:00
abstract::To investigate the specificity of terminal deoxynucleotidyl transferase (TdT) as a marker for lymphoblastic lymphoma in the non-Hodgkin's lymphomas, the authors assayed malignant cells from 142 patients with non-Hodgkin's malignant lymphoma, as well as cells from normal lymphoid tissue controls. Neoplastic cells from ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/80.5.655
更新日期:1983-11-01 00:00:00
abstract::We report 8 cases of hepatosplenic T-cell lymphoma (HSTCL) involving bone marrow and correlate histologic findings with disease progression. Immunophenotypic analysis demonstrated mature, aberrant gamma/delta T-cell immunophenotypes. Isochromosome 7q was identified in 4 cases; 1 case showed the t(7;14)(q34;q13). Seven...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/BM40-YM6J-9T3X-MH8H
更新日期:2001-09-01 00:00:00
abstract::A 52-year-old woman presented with a solid spindle cell primary tumor of the lymph node. On light microscopic examination, mitoses and cellular atypia were absent. Electron-microscopic studies showed endothelial cell differentiation. Intracytoplasmic localization of Factor VIII-related antigen was demonstrated by the ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/85.6.731
更新日期:1986-06-01 00:00:00
abstract::A 75-year-old man with Staphylococcus aureus endocarditis in whom acute diffuse proliferative glomerulonephritis developed is described. The light- and electron-microscopic changes of the glomeruli in this case were identical to those of acute poststreptococcal glomerulonephritis. Immunofluorescence revealed depositio...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/70.5.832
更新日期:1978-11-01 00:00:00
abstract::Blood glucose results for 2,601 specimens obtained at multiphasic health examination, divided into three age groups, were analyzed using probability plot paper. Two straight lines could be fitted to each distribution. The assumption was made that the lower lines correspond to "normal-healthy" persons, whereas the uppe...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/76.2.211
更新日期:1981-08-01 00:00:00
abstract::Two radioimmunoassay procedures (RIA-1 and RIA-2) were evaluated for the quantitation of prostatic acid phosphatase in serum and compared with the enzymatic method and counter immunoelectrophoresis method for their specificity and sensitivity. Sera from 168 patients were analyzed and these included: normals, 27; untre...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/76.4.430
更新日期:1981-10-01 00:00:00
abstract::Telepathology is gaining acceptance as a mode of providing pathology services to remote sites, but its economic feasibility is unknown. A dynamic robotic telepathology service between the Veterans Affairs Medical Center, Iron Mountain, MI, and the Veterans Affairs Medical Center, Milwaukee, WI, provides diagnostic ser...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/112.4.470
更新日期:1999-10-01 00:00:00
abstract:OBJECTIVES:Bone marrow (BM) biopsy specimens involved by systemic mastocytosis (SM) typically show multifocal, compact, dense aggregates of spindled mast cells (MCs). However, some cases lack aggregate formation and fulfill the World Health Organization 2008 criteria for SM, based on minor criteria. METHODS:We identif...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/AJCPSGQ71GJQQACL
更新日期:2015-09-01 00:00:00
abstract::The Department of Laboratory Medicine, University of Washington, has explored various management of organizational approaches over the past seven years. The Centralized Processing Area supported by a computerized information system has evolved from these efforts. Despite a decrease in U.W. hospital usage since 1968-69...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/67.2.149
更新日期:1977-02-01 00:00:00
abstract:Objectives:To curtail inappropriate plasma transfusions, we instituted clinical decision support as an alert upon order entry if the patient's recent international normalized ratio (INR) was 1.7 or less. Methods:The alert was suppressed for massive transfusion and within operative or apheresis settings. The plasma ord...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/aqx061
更新日期:2017-08-01 00:00:00
abstract::In view of their reported reciprocal effects on apoptosis, the expression of p53 and bcl-2 proteins was studied in 46 cases of Hodgkin's disease by immunocytochemical labeling. We found p53 protein in Reed-Sternberg cells and their mononuclear variants in 16 of the 46 cases (34.7%) of Hodgkin's disease, mainly in a nu...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/99.6.663
更新日期:1993-06-01 00:00:00
abstract::Therapeutic control achieved by an anticoagulant clinic may be assessed by calculation of the proportion of time spent by the patients within the prothrombin time target range aimed for by the clinic. Three calculation methods for such assessment have been described by other investigators. The three methods were compa...
journal_title:American journal of clinical pathology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1093/ajcp/90.6.685
更新日期:1988-12-01 00:00:00
abstract::Peripheral blood mononuclear cells from pemphigus vulgaris and bullous pemphigoid patients produced antiepithelial antibodies in a pokeweed mitogen-stimulated in vitro cell culture system. Antiintercellular substance (ICS) antibodies were detected in supernatants of cell cultures from four of four pemphigus vulgaris p...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/81.5.586
更新日期:1984-05-01 00:00:00
abstract::This report describes the selective staining of lysosomes in cells of neutrophilic granulocytic origin by the azo textile dye basic blue 93. Used as a single agent aqueous stain after fixation, the dye stained lysosomes black. Stained in this way, lysosomes were sharply delimited and easily visualized. Large numbers o...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/89.2.195
更新日期:1988-02-01 00:00:00
abstract::The authors evaluated the Yellow IRIS automated urinalysis instrument (International Remote Imaging Systems, Chatsworth, CA 91311) in terms of its analytic performance as well as its ease of use. The Yellow IRIS is a system using automated intelligence microscopy (AIM), coupled with a dipstick reader and specific grav...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/86.5.661
更新日期:1986-11-01 00:00:00
abstract::A 73-year-old man with myelodysplastic syndrome developed during the course of his illness auto-immune hemolytic anemia. The association between auto-immune hemolysis and myeloproliferative disease is extremely rare. An even more unique finding is the nature of the antibody which demonstrated single specificity agains...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/77.3.356
更新日期:1982-03-01 00:00:00
abstract::Human serum contains 2 isoforms of type-5 tartrate-resistant acid phosphatase (TRACP): 5a and 5b. TRACP-5b is osteoclastic. Our goal was to determine if serum TRACP-5a could originate from inflammatory macrophages (MPhi). We stained 246 paraffin-embedded tissue samples for TRACP using monoclonal antibody 9C5 (mab9C5) ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/DGEA9BE2VE5VCFYH
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVES:To correlate human herpesvirus 6 (HHV-6) viral load with pathologic features in graft acute hepatitis of unknown origin. METHODS:Liver frozen samples from 26 patients with graft hepatitis of unknown origin were available for HHV-6 DNA quantification. RESULTS:In 10 (38.5%) of 26 liver samples, HHV-6 DNA was...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/AJCP0FWI2XAHECBJ
更新日期:2013-09-01 00:00:00
abstract::Immunohistochemical expression of napsin A in primary pulmonary mucinous tumors is not well established. Napsin A immunoreactivity was evaluated in 43 mucin-producing adenocarcinomas of the lung consisting of 18 tumors formerly classified as mucinous bronchioloalveolar carcinoma, 15 colloid adenocarcinomas, 5 solid pr...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/AJCP62WJUAMSZCOM
更新日期:2013-02-01 00:00:00
abstract::Immunocytochemical assays for progesterone receptor (PR) using monoclonal antirabbit PR antibodies (PR-ICA) and for estrogen receptor (ER) (ER-ICA) were compared with radioligand binding (dextran-coated charcoal [DCC]) methods for receptor determination in patients with breast cancer. Immunocytochemical staining for P...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract:OBJECTIVES:Preanalytical factors, such as hemolysis, affect many components of a test panel. Machine learning can be used to recognize these patterns, alerting clinicians and laboratories to potentially erroneous results. In particular, machine learning might identify which cases of elevated potassium from a point-of-c...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/aqaa039
更新日期:2020-07-07 00:00:00
abstract::A goat anti-serum was prepared against mucinous ovarian cyst fluid and absorbed with normal colon and a variety of normal tissues until the only residual immunoreactivity was directed against colon cancer and ovarian tumor mucin. The set of antigenic determinants defined by this anti-serum has been called COTA, standi...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/86.1.1
更新日期:1986-07-01 00:00:00
abstract:OBJECTIVES:Bladder cancers invading the muscularis mucosae (MM) are treated differently from those invading the muscularis propria (MP). However, it may be difficult to determine the type of smooth muscle in transurethral resection (TUR) or biopsy specimens. We aimed to investigate the clinicopathologic features of bla...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/aqaa030
更新日期:2020-07-07 00:00:00
abstract::Adenovirus was cultured from various gastrointestinal sites and one lung specimen from seven immunosuppressed patients, four of whom were bone marrow transplant recipients. Histologic examination and in situ hybridization studies of the lung demonstrated adenovirus in the bronchial epithelium and alveolar lining cells...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/97.4.555
更新日期:1992-04-01 00:00:00
abstract::Thirty drugs used primarily in critical care and hospital settings were tested in vitro to observe interference on glucose measurements with 6 hand-held glucose meters and a portable glucose analyzer. Paired differences of glucose measurements between drug-spiked samples and unspiked control samples were calculated to...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/QAW1-X5XW-BVRQ-5LKQ
更新日期:2000-01-01 00:00:00
abstract::A proportion of patients under surveillance for recurrent bladder carcinoma with no immediate evidence of bladder tumor recurrence have positive multitarget fluorescence in situ hybridization (FISH; UroVysion, Vysis, Downers Grove, IL) results. The course of these "anticipatory positive" cases and the time to bladder ...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/ADJL7E810U1H42BJ
更新日期:2007-02-01 00:00:00
abstract::Three stillborn fetuses are reported in which an abdominal wall defect was associated with defects in the urogenital and anal region. Autopsy of these fetuses provided clues indicative of how and where the embryonic development went wrong. The malformation involved a disturbance of the cell deposition process, occurri...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/96.5.640
更新日期:1991-11-01 00:00:00
abstract::The characteristics of the normal adult thymus in both sexes were determined in 50 cases of accidental death by a simplified quantitative histologic technic. A table of normal values derived from these findings was used for making comparisons with thymus from autopsies of 50 additional patients suffering terminal illn...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/76.5.657
更新日期:1981-11-01 00:00:00