Inherited giant platelet disorders. Classification and literature review.

Abstract:

:Inherited giant platelet disorders are extremely rare. The aim of this article is to review the clinical and laboratory features of this heterogeneous group and to arrive at a working classification. We conducted our literature search using the National Library of Medicine database. A total of 12 clinical entities were described. We classified them into 4 groups depending on the clinical and structural abnormalities. The pathophysiology of these disorders is largely unknown, and more research is needed, particularly in the light of recent advances in laboratory medicine. This review may provide a valuable reference for clinicians and may form a basis for future classification and research.

journal_name

Am J Clin Pathol

authors

Mhawech P,Saleem A

doi

10.1309/FC4H-LM5V-VCW8-DNJU

subject

Has Abstract

pub_date

2000-02-01 00:00:00

pages

176-90

issue

2

eissn

0002-9173

issn

1943-7722

journal_volume

113

pub_type

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