Reproducibility of mean values of duplicate specimens in the Basic Ligand Assay Survey.

abstract：:Diffuse alveolar damage (DAD) is usually considered a generalized lung process. During five years the authors observed 83 patients with generalized DAD in 827 adult autopsies (10.1%) and 10 patients with identical, but localized, lesions. The authors propose the term regional alveolar damage (RAD) to designate localiz...

journal_title：American journal of clinical pathology

authors： Yazdy AM,Tomashefski JF Jr,Yagan R,Kleinerman J

更新日期：1989-07-01 00:00:00

abstract：:There are few studies that examine prevalence, quantity, and cellular proclivity of latent human herpesvirus 6 (HHV-6) in healthy populations. We examined 69 tonsils with paired blood specimens from children without evidence of acute infection. By polymerase chain reaction (PCR), HHV-6 was detected at low levels in 10...

journal_title：American journal of clinical pathology

authors： Roush KS,Domiati-Saad RK,Margraf LR,Krisher K,Scheuermann RH,Rogers BB,Dawson DB

更新日期：2001-11-01 00:00:00

abstract：:Accurate diagnosis of oral hairy leukoplakia (OHL) is important because it may be an early indicator of undiagnosed HIV infection; moreover, it may be a prognostic indicator. Our purpose was to investigate the histopathologic features of subclinical OHL and to evaluate and support the rationale of detecting subclinica...

journal_title：American journal of clinical pathology

authors： Dias EP,Rocha ML,Silva JúniorA,Spyrides KS,Ferreira SM,Polignano GA,Feijó EC,Da Fonseca EC

更新日期：2000-09-01 00:00:00

abstract：:Immunohistochemistry occasionally is used to determine the lineage of entirely necrotic tumors. However, the sensitivity and specificity of antibodies on necrotic tissue are unknown. To determine the usefulness of immunohistochemistry with necrotic lesions, a series of 24 known tumors consisting of 14 carcinomas, 2 ly...

journal_title：American journal of clinical pathology

authors： Judkins AR,Montone KT,LiVolsi VA,van de Rijn M

更新日期：1998-11-01 00:00:00

abstract：Objectives:Diagnosis of B-cell acute lymphoblastic leukemia (B-ALL) requires immunophenotypic evidence of B-lineage and absence of specific myeloid or T-lineage markers. Rare cases of otherwise typical B-ALL express myeloperoxidase (MPO) detectable by flow cytometry with an absence of other myeloid markers, but the cli...

journal_title：American journal of clinical pathology

authors： Oberley MJ,Li S,Orgel E,Phei Wee C,Hagiya A,O'Gorman MRG

更新日期：2017-04-01 00:00:00

abstract：:The authors describe the case of a 33-year-old man with a solitary cystic lesion of the left distal radius with central radiodensities that radiographically suggested a chondroid matrix. Curettage of the lesion revealed numerous calcospherites with a lamellar structure. This lamellar pattern is thought to be a result ...

journal_title：American journal of clinical pathology

authors： Kragel PJ,Williams J,Garvin DF,Goral AB

更新日期：1989-12-01 00:00:00

abstract：OBJECTIVES:Meningiomas usually can be readily diagnosed on H&E alone, although occasionally immunohistochemistry (IHC) confirmation is desirable. Studies exploring the diagnostic utility of either podoplanin (D2-40) or E-cadherin IHC in meningiomas have conflicted, and no studies exist in which the two IHCs have been u...

journal_title：American journal of clinical pathology

authors： Mrachek EK,Davis D,Kleinschmidt-DeMasters BK

更新日期：2015-12-01 00:00:00

abstract：:Histologic follow-up of patients with the Bethesda system cervical-vaginal diagnosis of atypical glandular cells of undetermined significance (AGUS), "favor endocervical origin", or "not otherwise specified" (NOS) shows a high percentage of clinically significant (neoplastic or preneoplastic) lesions. Using the criter...

journal_title：American journal of clinical pathology

authors： Raab SS,Snider TE,Potts SA,McDaniel HL,Robinson RA,Nelson DL,Sigman JD,Thomas PA

更新日期：1997-03-01 00:00:00

abstract：:The results obtained with eight pregnancy kits on 735 urines were compared. Overall accuracies were similar and fairly high (93.4 to 95.37%), although only 78.28% of all pregnancies were simultaneously detected by all eight kits. It is suggested that the different performances of each kit could be accounted for not on...

journal_title：American journal of clinical pathology

authors： Porres JM,D'Ambra C,Lord D,Garrity F

更新日期：1975-10-01 00:00:00

abstract：:We developed anecdotal evidence that parenteral iron therapy is associated with a characteristic pattern of iron staining in bone marrow aspirate smears. In this pattern, uniform blue granules are observed within reticuloendothelial cells/stromal cells with Prussian blue staining, many times in curvilinear arrays. To ...

journal_title：American journal of clinical pathology

authors： Thomason RW,Lavelle J,Nelson D,Lin K,Uherova P

更新日期：2007-10-01 00:00:00

abstract：:Overexpression and amplification of the HER-2 oncogene in patients with breast cancer has correlated with early onset of metastasis, resistance to hormonal therapy and some forms of chemotherapy, and shortened survival. Therefore, evaluation of this putative prognostic or predictive factor seems critical. Because diff...

journal_title：American journal of clinical pathology

authors： Gancberg D,Lespagnard L,Rouas G,Paesmans M,Piccart M,Di Leo A,Nogaret JM,Hertens D,Verhest A,Larsimont D

更新日期：2000-05-01 00:00:00

abstract：:Several laboratory methods are currently available for the detection of barbiturates, but few are suitable for emergency use, The authors evaluated use of an ultraviolet spectrophotometric method as a screening procedure and compared the results with results obtained by other barbiturate methods (colorimetric, gas-li...

journal_title：American journal of clinical pathology

authors： Schumann GB,Lauenstein K,LeFever D,Henry JB

更新日期：1976-11-01 00:00:00

abstract：:We compared a rapid, point-of-care multimarker protocol with a single and serial troponin I (TnI)-only protocol in 5,244 patients admitted to the emergency department with chest pain. The diagnosis of acute myocardial infarction (AMI) was based on a doubling myoglobin level accompanied by at least a 50% increase in th...

journal_title：American journal of clinical pathology

authors： Straface AL,Myers JH,Kirchick HJ,Blick KE

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVES:Sclerosing pneumocytomas are rare pulmonary neoplasms that are typically benign. However, rare patients experience progressive disease, and therapy targeting specific genetic underpinnings could be an attractive therapeutic option. Recent studies have found recurrent AKT 1 mutations in sclerosing pneumocytom...

journal_title：American journal of clinical pathology

authors： Boland JM,Lee HE,Barr Fritcher EG,Voss JS,Jessen E,Davila JI,Kipp BR,Graham RP,Maleszewski JJ,Yi ES

更新日期：2020-11-04 00:00:00

abstract：:Conventional cytogenetic studies have suggested that trisomy 12 may be a characteristic nonrandom numerical chromosome anomaly in benign ovarian tumors, particularly sex cord-stromal tumors. To confirm this finding, and to avoid possible culture artifact introduced during cytogenetic analysis, the authors performed fl...

journal_title：American journal of clinical pathology

authors： Persons DL,Hartmann LC,Herath JF,Keeney GL,Jenkins RB

更新日期：1994-12-01 00:00:00

abstract：:This study describes results of fresh-frozen immunohistochemistry applied to two typical Warthin's tumors. Polyclonal follicular center cell staining and an apparent reduction in the number of T-lymphocytes were found. These observations tend to support the concept that the lymphoid infiltrate in Warthin's tumor repre...

journal_title：American journal of clinical pathology

authors： Tubbs RR,Sheibani K,Weiss RA,Lee V,Sebek BA,Valenzuela R

更新日期：1980-12-01 00:00:00

abstract：:The radioimmunoassay of ACTH was used in a routine laboratory to localize the site of the lesion in 20 patients with Cushing's syndrome. Eight of the patients had no detectable circulating ACTH and had adrenal tumors removed, 12 had high levels and were diagnosed as having pituitary Cushing's syndrome. Very high level...

journal_title：American journal of clinical pathology

authors： Broughton A

更新日期：1975-11-01 00:00:00

abstract：:During a three-year period, Staphylococcus aureus and Pseudomonas aeruginosa were the organisms most commonly isolated from blood cultures of burned children. Microorganisms were considered to contribute to the cause of death in 17 of 20 patients who died from various complications of thermal injuries. Pseudomonas aer...

journal_title：American journal of clinical pathology

authors： Smith RF,Linares HA,Jorgensen JH

更新日期：1975-04-01 00:00:00

abstract：:This report describes the selective staining of lysosomes in cells of neutrophilic granulocytic origin by the azo textile dye basic blue 93. Used as a single agent aqueous stain after fixation, the dye stained lysosomes black. Stained in this way, lysosomes were sharply delimited and easily visualized. Large numbers o...

journal_title：American journal of clinical pathology

authors： Kass L

更新日期：1988-02-01 00:00:00

abstract：:Two monoclonal antibodies, UCD/AB 6.11 and UCD/PR 10.11, were evaluated for their patterns of immunohistochemical reactivity in a survey of paraffin-embedded human tissues by the avidin-biotin-immunoperoxidase technique. By two-dimensional immunoblotting, UCD/AB 6.11 reacts with keratin number 18 and UCD/PR 10.11 iden...

journal_title：American journal of clinical pathology

authors： Chan R,Edwards BF,Hu R,Rossitto PV,Min BH,Lund JK,Cardiff RD

更新日期：1988-04-01 00:00:00

abstract：:Pancreatic adenocarcinoma is believed to develop from histologically identifiable intraductal lesions known as pancreatic intraepithelial neoplasias (PanINs) that undergo a series of architectural, cytologic, and genetic changes, a progression model similar to the adenoma-carcinoma sequence in the colon. The apomucin ...

journal_title：American journal of clinical pathology

authors： Swartz MJ,Batra SK,Varshney GC,Hollingsworth MA,Yeo CJ,Cameron JL,Wilentz RE,Hruban RH,Argani P

更新日期：2002-05-01 00:00:00

abstract：:The authors investigated the stability of the tests comprising the SMA-6 and SMA-12 chemistry profiles during overnight refrigerated storage. Several constituents were found to undergo changes that were statistically significant when evaluated by a t test for paired comparisons. A recently published sequential method ...

journal_title：American journal of clinical pathology

authors： Rossing RG,Foster DM

更新日期：1980-01-01 00:00:00

abstract：:Estrogen receptor (ER) status of breast carcinomas determines prognosis and treatment. Biochemical ER assays are expensive and time-consuming and require fresh tumor. Immunohistochemical ER was assessed in 68 breast carcinomas, by an automated method using routinely processed formalin-fixed paraffin-embedded tissues, ...

journal_title：American journal of clinical pathology

authors： Cohen C,Unger ER,Sgoutas D,Bradley N,Chenggis M

更新日期：1989-11-01 00:00:00

abstract：:The ATHENA (Addressing THE Need for Advanced HPV Diagnostics) HPV study evaluated the clinical usefulness of the cobas HPV Test (Roche Molecular Systems, Pleasanton, CA) for high-risk human papillomavirus (HR-HPV) testing (14 HR types) and individual HPV-16/HPV-18 genotyping in women undergoing routine cervical cytolo...

journal_title：American journal of clinical pathology

authors： Wright TC Jr,Stoler MH,Sharma A,Zhang G,Behrens C,Wright TL,ATHENA (Addressing THE Need for Advanced HPV Diagnostics) Study Group.

更新日期：2011-10-01 00:00:00

abstract：:Pseudomonas alcaligenes is a common soil and water inhabitant that has rarely been proven a human pathogen. We describe a fatal case of Pseudomonas alcaligenes endocarditis. The need for accurate identification of unusual organisms isolated in a clinical setting are discussed. ...

journal_title：American journal of clinical pathology

authors： Valenstein P,Bardy GH,Cox CC,Zwadyk P

更新日期：1983-02-01 00:00:00

abstract：:Percent-free prostate-specific antigen (proportion of free prostate-specific antigen [PSA] to total PSA) has been shown recently in studies on frozen serum samples to be more useful than total PSA alone in distinguishing prostate cancer from benign conditions of the prostate gland. The primary purpose of our study was...

journal_title：American journal of clinical pathology

authors： Henricks WH,England BG,Giacherio DA,Oesterling JE,Wojno KJ

更新日期：1998-05-01 00:00:00

abstract：:The Philadelphia chromosome (Ph) is found in most chronic myelogenous leukemia (CML) patients. The bcr-abl oncoprotein (P210 or P185), the product of the fused bcr-abl gene produced by the Ph, is known to be the major factor in initiation and maintenance of the leukemic state in these types of leukemias. The authors h...

journal_title：American journal of clinical pathology

authors： Guo JQ,Lian J,Glassman A,Talpaz M,Kantarjian H,Deisseroth AB,Arlinghaus RB

更新日期：1996-10-01 00:00:00

abstract：:Eight cases are reported of an unusual breast lesion consisting of dense intralobular, perilobular, and perivascular lymphocytic infiltrates associated with lobular atrophy and sclerosis. Immunologic studies on paraffin-embedded tissue (seven cases) and frozen tissue (two cases) demonstrated a predominance of B-cells ...

journal_title：American journal of clinical pathology

authors： Schwartz IS,Strauchen JA

更新日期：1990-06-01 00:00:00

abstract：:Posttransplantation lymphoproliferative disorders (PT-LPDs) occurring in T-cell depleted (TCD) allogeneic bone marrow transplant recipients seem to be different from those that arise in solid organ recipients in their early development, the high incidence of extensive dissemination at presentation, and their aggressiv...

journal_title：American journal of clinical pathology

authors： Orazi A,Hromas RA,Neiman RS,Greiner TC,Lee CH,Rubin L,Haskins S,Heerema NA,Gharpure V,Abonour R,Srour EF,Cornetta K

更新日期：1997-04-01 00:00:00

abstract：:We optimized fluorogenic thrombin-generation assays with regard to sample volume, calibration, analytic corrections, and activation reagents. Lower sample volumes (40 vs 80 microL) were associated with better recovery of thrombin activity, lower interference due to absorbance of light, and higher total thrombin genera...

journal_title：American journal of clinical pathology

authors： Chandler WL,Roshal M

更新日期：2009-08-01 00:00:00