Sensitivity of HER-2/neu antibodies in archival tissue samples of invasive breast carcinomas. Correlation with oncogene amplification in 160 cases.

abstract：:The immunochemical characterization of the light chains of the mesangial immunoglobulin A (IgA) deposits were studied in 45 patients with IgA nephropathy. Kappa and lambda light chains were detected with direct immunofluorescence (IF) method, using monospecific rabbit anti-human anti-kappa and anti-lambda anti-sera. T...

journal_title：American journal of clinical pathology

authors： Lai KN,Chan KW,Mac-Moune F,Ho CP,Yan KW,Lam CW,Vallance-Owen J

更新日期：1986-05-01 00:00:00

abstract：:The most commonly used fixative in effusion cytology is formalin. In the present study, the immunocytochemical properties of formalin-fixed and alcohol-fixed specimens were compared to evaluate the usefulness of alcohol-fixed cytocentrifuged preparations for routine cytologic diagnosis. A total of 269 effusion samples...

journal_title：American journal of clinical pathology

authors： Ikeda K,Tate G,Suzuki T,Mitsuya T

更新日期：2011-12-01 00:00:00

abstract：:Minimal inhibitory concentrations (MICs) of clindamycin, cefoxitin, imipenem, and metronidazole were determined by the E-Test and a reference agar dilution method for 92 gram-negative anaerobic organisms. For 335 MIC pairs, the agreement between the two systems was 80.1%; 60 (17.9%) differed by two or more twofold dil...

journal_title：American journal of clinical pathology

authors： Couroux PR,Massey VE,Schieven BC,Lannigan R,Hussain Z

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVES:To establish an objective, scientific, evidence-based process for planning statistical quality control (SQC) procedures based on quality required for a test, precision and bias observed for a measurement procedure, probabilities of error detection and false rejection for different control rules and numbers o...

journal_title：American journal of clinical pathology

authors： Westgard JO,Westgard SA

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:Mesothelin (MSLN) is a differentiation antigen found to be overexpressed in intraductal papillary mucinous neoplasms (IPMNs) and is a potential treatment target in pancreatic ductal adenocarcinoma. METHODS:From institutional archives, 114 cases of resected pancreatic mucinous cysts were identified, includin...

journal_title：American journal of clinical pathology

authors： Frank R,Li S,Ahmad NA,Sepulveda AR,Jhala NC

更新日期：2014-09-01 00:00:00

abstract：:The authors studied the effect of averaging replicated assays of Factor IX coagulation activity and Factor IX antigen on each plasma specimen in improving the ability to detect carriers of hemophilia B. The improvement resulting from this procedure is particularly marked in tests depending on the linear regression of ...

journal_title：American journal of clinical pathology

authors： Lipworth L,Tiarks CY,Rice CA,Pechet L

更新日期：1979-12-01 00:00:00

abstract：OBJECTIVES:To assess the frequency of systemic mastocytosis (SM) in a large series of acute myeloid leukemia (AML) with t(8;21)(q22;q22). METHODS:We retrospectively characterized 40 bone marrow aspirate smears and biopsy specimens from patients with AML with t(8;21) for the presence of SM. Cases were assessed for mast...

journal_title：American journal of clinical pathology

authors： Johnson RC,Savage NM,Chiang T,Gotlib JR,Cherry AM,Arber DA,George TI

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVES:Although diffuse alveolar damage, a subtype of acute lung injury (ALI), is the most common microscopic pattern in coronavirus disease 2019 (COVID-19), other pathologic patterns have been described. The aim of the study was to review autopsies from COVID-19 decedents to evaluate the spectrum of pathology and ...

journal_title：American journal of clinical pathology

authors： De Michele S,Sun Y,Yilmaz MM,Katsyv I,Salvatore M,Dzierba AL,Marboe CC,Brodie D,Patel NM,Garcia CK,Saqi A

更新日期：2020-11-04 00:00:00

abstract：:We examined benign and malignant mesothelial tissue samples for the presence of X-linked inhibitor of apoptosis protein (XIAP), a potent constituent of the inhibitor of apoptosis family of caspase inhibitors. We subjected 55 sections (31 malignant mesotheliomas, 2 well-differentiated peritoneal mesotheliomas, 13 pleur...

journal_title：American journal of clinical pathology

authors： Wu M,Sun Y,Li G,Desman G,Wang B,Gil J,Burstein DE

更新日期：2007-11-01 00:00:00

abstract：:Multiparameter flow cytometry with optimally selected antibody combinations has expanded the use of this technique beyond traditional applications in hematopathology. By analyzing qualitative patterns of antigen expression on discrete populations or "clusters," one can detect immunophenotypic aberrancy in specific cel...

journal_title：American journal of clinical pathology

authors： Kroft SH

更新日期：2004-12-01 00:00:00

abstract：:Although the relationship between pathologic features and clinical outcome is well established in adult adrenocortical neoplasms, the prognostic value of these features in pediatric adrenocortical neoplasms (PACN) is unclear. In a series of PACNs from 54 Brazilian children, the authors retrospectively investigated the...

journal_title：American journal of clinical pathology

authors： Bugg MF,Ribeiro RC,Roberson PK,Lloyd RV,Sandrini R,Silva JB,Epelman S,Shapiro DN,Parham DM

更新日期：1994-05-01 00:00:00

abstract：:Platelet volume measurements have been used to differentiate consumptive and hypoplastic thrombocytopenia. Since thrombocytopenia is a frequent complication of neonatal sepsis, the authors explored the utility of correlating mean platelet volume (MVP) and platelet distribution width (PDW) with bacteremia. In a sample ...

journal_title：American journal of clinical pathology

authors： Patrick CH,Lazarchick J

更新日期：1990-03-01 00:00:00

abstract：Objectives:To determine non-American Society for Clinical Pathology pathology- and laboratory-related Choosing Wisely recommendations that drive effective test utilization in the laboratory. Methods:Data were collected via a two-part web-based survey distributed to a broad sample of pathologists and laboratory profess...

journal_title：American journal of clinical pathology

authors： Waibel E,Garcia E,Kelly M,Soles R,Hilborne L

更新日期：2018-02-17 00:00:00

abstract：:Proliferative lesions, which include collagen, elastic fibers and abnormally oriented muscle fibers, were found to develop in intramyocardial arteries more rapidly with age in cigarette smokers than in nonsmokers. The study attempted to determine whether these lesions reduce perfusion pressures in the subendocardial z...

journal_title：American journal of clinical pathology

authors： Naeye RL,Truong LD

更新日期：1977-10-01 00:00:00

abstract：OBJECTIVES:Bone marrow (BM) biopsy specimens involved by systemic mastocytosis (SM) typically show multifocal, compact, dense aggregates of spindled mast cells (MCs). However, some cases lack aggregate formation and fulfill the World Health Organization 2008 criteria for SM, based on minor criteria. METHODS:We identif...

journal_title：American journal of clinical pathology

authors： Reichard KK,Chen D,Pardanani A,McClure RF,Howard MT,Kurtin PJ,Wood AJ,Ketterling RP,King RL,He R,Morice WG,Hanson CA

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVES:To investigate metastasis associated in colon cancer 1 (MACC1) and MET expression in colorectal adenoma, Tis, early-stage invasive (T1 and T2), and advanced adenocarcinoma with liver metastasis using immunohistochemistry. METHODS:Ninety-three paraffin-embedded colorectal tumor specimens were immunohistochem...

journal_title：American journal of clinical pathology

authors： Ren B,Zakharov V,Yang Q,McMahon L,Yu J,Cao W

更新日期：2013-11-01 00:00:00

abstract：:We reviewed 500 consecutive soft tissue lesions referred for expert consultation to determine types of lesions and/or situations in which major discrepancies occur. Of 266 cases (53.2%) accompanied by a diagnosis, essential agreement with the second opinion was noted in 68%, minor discrepancy in 7%, and major discrepa...

journal_title：American journal of clinical pathology

authors： Arbiser ZK,Folpe AL,Weiss SW

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVES:BCOR-CCNB3 sarcoma (BCS) is an undifferentiated tumor that has some clinical and morphologic similarity to classic Ewing sarcoma, but it is characterized by a distinct BCOR-CCNB3 gene fusion. There are no reports describing its cytomorphologic findings. METHODS:We describe cytologic findings of five molecul...

journal_title：American journal of clinical pathology

authors： Gajdzis P,Laé M,Pierron G,Brisse HJ,Orbach D,Fréneaux P,Laurence V,Klijanienko J

更新日期：2020-02-08 00:00:00

abstract：:Analysis of the data for the 1969 to 1973 CAP Surveys of proficiency in partial thromboplastin time (PTT) determination indicates more than desirable variability in this measurement. Non-activated procedures show greater interlaboratory variability than activated methods; therefore, they may be preferable for routine ...

journal_title：American journal of clinical pathology

authors： Koepke JA

更新日期：1975-06-01 00:00:00

abstract：:This article describes the seventh known case of blue nevus of the lymph node capsule and reviews the previously reported cases. The migration arrest hypothesis as an explanation for the occurrence of this lesion is favored rather than the "benign metastasis" hypothesis. The importance of the recognition of this pheno...

journal_title：American journal of clinical pathology

authors： Lamovec J

更新日期：1984-03-01 00:00:00

abstract：:We compared prothrombin times (PTs) and international normalized ratios (INRs) for blood samples drawn into plastic vs glass collection tubes. We collected 60 venous blood samples into 4.5-mL glass and 2 plastic tubes (2.7 and 3.5 mL). An additional 153 samples, including 63 from warfarin-anticoagulated patients, were...

journal_title：American journal of clinical pathology

authors： Fiebig EW,Etzell JE,Ng VL

更新日期：2005-12-01 00:00:00

abstract：:To verify their clinical usefulness in diagnosis and early response to therapy of sideropenic anemia, we compared the behavior of the reticulocyte parameter (RET-Y), a raw measure dependent on size and content of the cell, generated by the Sysmex XE 2100, with the mean reticulocyte volume (MCVr) and mean reticulocyte ...

journal_title：American journal of clinical pathology

authors： Buttarello M,Temporin V,Ceravolo R,Farina G,Bulian P

更新日期：2004-04-01 00:00:00

abstract：:Recombinant factor VIIa (rFVIIa) has become available for treating people with hemophilia with inhibitors who experience bleeding or require surgery. It has become apparent that rFVIIa is useful in controlling bleeding in a variety of clinical situations. This review attempts to collate and summarize the nonhemophilia...

journal_title：American journal of clinical pathology

authors： Midathada MV,Mehta P,Waner M,Fink LM

更新日期：2004-01-01 00:00:00

abstract：:This review summarizes our experience using blinded review as a method to measure quality in surgical pathology. It details the specifics about how the review is performed, the weaknesses in the method, and then summarizes our results so far. These results suggest that error rates correlate with the individual patholo...

journal_title：American journal of clinical pathology

authors： Renshaw AA,Gould EW

更新日期：2007-01-01 00:00:00

abstract：:The incubation of stored blood in a mixture of inosine, pyruvate, glucose, and phosphate restores the O2 affinity of hemoglobin to physiologic levels, as measured by the configuration of the dissociation curve and the P50. This regeneration of normal hemoglobin function not only is consistent for samples anticoagulate...

journal_title：American journal of clinical pathology

authors： Sumoza A,Fairbanks VF,Pineda AA

更新日期：1977-07-01 00:00:00

abstract：:Forty-three laboratories participated in an interlaboratory testing program offered by the College of American Pathologists for the radioimmunoassay (RIA) of carcinoembryonic antigen (CEA). Thirty correctly reported a sample with 1.9 ng of endogenous CEA per ml as less than 2.5 ng. For samples with added exogenous CEA...

journal_title：American journal of clinical pathology

authors： Reynoso G,Keane M,Konopka S

更新日期：1977-07-01 00:00:00

abstract：:An evaluation of the validity in infants of standard computations for the correction of white cell counts in blood-contaminated cerebrospinal fluid (traumatic lumbar puncture) was undertaken. In 39 infants with significant blood contamination (greater than 10(4) red blood cells/microL) and no evidence of bacterial men...

journal_title：American journal of clinical pathology

authors： Novak RW

更新日期：1984-07-01 00:00:00

abstract：:Two commercial enzyme-linked immunosorbent assays (ELISA) for detection of herpes simplex virus (HSV) antigen in direct clinical specimens were compared with cell culture in primary rabbit kidney and MRC-5. With a total of 238 specimens, the sensitivity and specificity of the Dako ELISA method were determined to be 70...

journal_title：American journal of clinical pathology

authors： Warford AL,Levy RA,Strong CA,Rekrut KA

更新日期：1986-02-01 00:00:00

abstract：:Pseudo-Pelger-Huët anomaly (PPHA) has been documented in association with transplant medications and other drugs. This iatrogenic neutrophilic dysplasia is reversible with cessation or adjustment of medications but is frequently confused with myelodysplastic syndrome (MDS) based on the conventional concept that PPHA i...

journal_title：American journal of clinical pathology

authors： Wang E,Boswell E,Siddiqi I,Lu CM,Sebastian S,Rehder C,Huang Q

更新日期：2011-02-01 00:00:00

abstract：:Two patients with chronic myelogenous leukemia (CML) developed blast crisis that morphologically appeared to be the microgranular variant of acute promyelocytic leukemia. This represented 8% of CML patients developing blast crisis from 1984 to 1993. Cytogenetic studies revealed translocation 15;17 in addition to trans...

journal_title：American journal of clinical pathology

authors： Rosenthal NS,Knapp D,Farhi DC

更新日期：1995-02-01 00:00:00