The effect of bacteremia on automated platelet measurements in neonates.

Abstract:

:Platelet volume measurements have been used to differentiate consumptive and hypoplastic thrombocytopenia. Since thrombocytopenia is a frequent complication of neonatal sepsis, the authors explored the utility of correlating mean platelet volume (MVP) and platelet distribution width (PDW) with bacteremia. In a sample of 156 infants, there was a significantly increased presence of bacteremia in those infants with MPV greater than 10.8 fL and/or PDW greater than 19.1%. High MPV and PDW showed high specificity for detecting bacteremia (95% and 79%, respectively), and had good negative predictive value. Neonates with blood cultures positive at birth (early infection) tended to have normal platelet volumes, while those infected after three days of age (late infection) had dramatic increases in MPV and PDW. Changes in MPV and PDW should be noted when the diagnosis of late sepsis is considered.

journal_name

Am J Clin Pathol

authors

Patrick CH,Lazarchick J

doi

10.1093/ajcp/93.3.391

subject

Has Abstract

pub_date

1990-03-01 00:00:00

pages

391-4

issue

3

eissn

0002-9173

issn

1943-7722

journal_volume

93

pub_type

杂志文章
  • Apolipoprotein A-I-derived amyloid in atherosclerosis. Its association with plasma levels of apolipoprotein A-I and cholesterol.

    abstract::Wild-type apolipoprotein A-I (apo A-I)-derived amyloid commonly occurs in atherosclerotic plaques. To clarify apo A-I amyloid formation, plasma levels of apo A-I and cholesterol were related to the presence of amyloid in atherosclerotic plaques in 15 patients with peripheral atherosclerosis, subjected to arterial reco...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/PJE6-X9E5-LX6K-NELY

    authors: Mucchiano GI,Jonasson L,Häggqvist B,Einarsson E,Westermark P

    更新日期:2001-02-01 00:00:00

  • Immunohistochemical characterization of renal amyloidosis.

    abstract::Forty-five renal biopsies with amyloidosis were studied by light microscopy with Congo red staining and action of potassium permanganate and by immunofluorescence with antihuman tissue A component antiserum antilight and heavy chains of immunoglobulins antisera. The patients were classified on the basis of concordance...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/87.6.756

    authors: Noel LH,Droz D,Ganeval D

    更新日期:1987-06-01 00:00:00

  • Expanded populations of surface membrane immunoglobulin light chain-negative B cells in lymph nodes are not always indicative of B-cell lymphoma.

    abstract::Immunophenotypic analysis is useful in distinguishing reactive from neoplastic lymphoproliferations, particularly when tissue is limited or histologic findings are equivocal. Surface membrane immunoglobulin (SmIg) light chain restriction in B cells is especially helpful in documenting clonality, and the loss of SmIg b...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/5R76B01VCATQLBK6

    authors: Zhao XF,Cherian S,Sargent R,Seethala R,Bonner H,Greenberg B,Bagg A

    更新日期:2005-07-01 00:00:00

  • A dissection of the CD45/side scatter "blast gate".

    abstract::CD45/side scatter (SS) gating is widely used for isolating blasts by flow cytometry (FC). However, other cells contaminate the "blast gate" (BG); CD45/SS gating is thus imprecise, particularly when there are few blasts. We studied the BG contents in 21 myelodysplastic syndromes (MDSs), 14 myeloproliferative neoplasms ...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCPN4G1IZPABRLH

    authors: Harrington AM,Olteanu H,Kroft SH

    更新日期:2012-05-01 00:00:00

  • SPLEEN/PATHOL.

    abstract::Lymphocyte subpopulations were studied in the peripheral blood, lymph nodes, and spleens in a group of 17 patients with untreated Hodgkin's disease. In 12 of 15 cases, diminished absolute levels of T-lymphocytes in the peripheral blood were found; however, this was correlated with total lymphopenia. No direct relation...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:

    authors: Bukowski RM,Noguchi S,Hewlett JS,Deodhar S

    更新日期:1976-01-01 00:00:00

  • Automation in clinical microbiology.

    abstract::Automation was introduced into the clinical microbiology laboratory in the 1960s but initially met with limited success. Today, instruments are an integral part of many clinical laboratories and are used for microbial detection, identification, and susceptibility testing; detection of positive blood cultures; screenin...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:

    authors: Woods GL

    更新日期:1992-10-01 00:00:00

  • Leukocyturia in cyclosporine-treated renal allograft recipients.

    abstract::Five hundred eighty-seven daily urine specimens were examined from 179 consecutive renal allograft recipients with the use of quantitative cytodiagnostic urinalysis. Specimens were divided between those patients receiving cyclosporine (CyA) and steroid immunotherapy (73 patients) and those receiving standard azathiopr...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/89.1.113

    authors: Ashton A,Alexander DP,DeBellis C,Schumann GB

    更新日期:1988-01-01 00:00:00

  • Cost analysis of point-of-care laboratory testing in a community hospital.

    abstract::Point-of-care testing (POCT) is a means of providing patient services more rapidly. Most evaluations of bedside laboratory testing devices have emphasized analytical performance in tertiary care settings. In contrast, the authors compare the operating cost of POCT for glucose and an electrolyte/glucose/blood urea nitr...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/103.2.240

    authors: Nosanchuk JS,Keefner R

    更新日期:1995-02-01 00:00:00

  • Antithrombin III and Factor VIII in patients with neoplasms.

    abstract::Possible increased activation of the coagulation pathway was measured in a group of patients with neoplastic diseases. In addition to standard tests, the thromboplastin generation test, thrombin generation test and immunologic and coagulant activities of both Factor VIII and antithrombin III were utilized in the evalu...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/68.2.258

    authors: Losito R,Beaudry P,Valderrama JC,Cousineau L,Longpré B

    更新日期:1977-08-01 00:00:00

  • Comparison of the E-test and reference agar dilution method for susceptibility of gram-negative anaerobic organisms.

    abstract::Minimal inhibitory concentrations (MICs) of clindamycin, cefoxitin, imipenem, and metronidazole were determined by the E-Test and a reference agar dilution method for 92 gram-negative anaerobic organisms. For 335 MIC pairs, the agreement between the two systems was 80.1%; 60 (17.9%) differed by two or more twofold dil...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/100.3.301

    authors: Couroux PR,Massey VE,Schieven BC,Lannigan R,Hussain Z

    更新日期:1993-09-01 00:00:00

  • The blood counts and lactate dehydrogenase levels in thrombotic thrombocytopenic purpura (TTP).

    abstract::The blood counts and lactic dehydrogenase values of eight patients with thrombotic thrombocytopenic purpura (TTP) were reviewed in relation to the clinical course. Three of the eight patients died. In these patients, the hemoglobin was significantly lower and the LDH higher at the time of presentation than that of the...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/80.5.700

    authors: Crowley JP,Metzger JB,L'Europa RA

    更新日期:1983-11-01 00:00:00

  • Quality school: an innovative approach to laboratory quality practices training.

    abstract::The quality management program in the Division of Transfusion Medicine at our institution had evolved to the point that the program generally was perceived to be the sole responsibility of our Quality Unit (which was administratively independent of day-to-day operations). It became clear that this administrative model...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/UHKMFRFTDRJ7MJ58

    authors: Foss ML,Moore SB

    更新日期:2005-10-01 00:00:00

  • Intrauterine infarction of a pulmonary segment in a full-term newborn. A case report.

    abstract::Intrauterine pulmonary infarction is extremely rare. In a series of 775 stillborn and newborn infants, only a few cases of acute pulmonary infarction were reported. The authors present the findings from a full-term infant who died at 9 hours of age of a chronic pulmonary infarction. Several pathogenic mechanisms, incl...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/100.6.701

    authors: Mirkin LD,Wong RC

    更新日期:1993-12-01 00:00:00

  • Lymphocytic mastopathy. An autoimmune disease of the breast?

    abstract::Eight cases are reported of an unusual breast lesion consisting of dense intralobular, perilobular, and perivascular lymphocytic infiltrates associated with lobular atrophy and sclerosis. Immunologic studies on paraffin-embedded tissue (seven cases) and frozen tissue (two cases) demonstrated a predominance of B-cells ...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/93.6.725

    authors: Schwartz IS,Strauchen JA

    更新日期:1990-06-01 00:00:00

  • Touch Preps of Products of Conception for Rule-Out Ectopic Pregnancy:  A Viable Alternative to Frozen Section.

    abstract:OBJECTIVES:Tissue confirmation of the intrauterine location of a pregnancy can be difficult grossly, necessitating a frozen section diagnosis. First-trimester tissue is often scant and can be exhausted by frozen section. We examined 39 endometrial curettings performed for rule-out ectopic pregnancy by touch prep to exa...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/aqw048

    authors: Chen AL,Tambouret RH,Roberts DJ

    更新日期:2016-06-01 00:00:00

  • Endometrial stromal sarcomas: immunoprofile with emphasis on HMB45 reactivity.

    abstract:OBJECTIVES:We describe the morphologic and immunohistochemical features of 17 endometrial stromal neoplasms, 16 sarcomas, and one stromal nodule. METHODS:We reviewed 35 cases interpreted as endometrial stromal neoplasms, but 17 high-grade endometrial stromal sarcomas (ESS) and one case of mixed endometrial sarcoma and...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCPS88CMJRXZBWA

    authors: Albores-Saavedra J,Dorantes-Heredia R,Chablé-Montero F,Chanona-Vilchis J,Pérez-Montiel D,Lino-Silva LS,González-Romo MA,Ramírez-Jaramillo JM,Henson DE

    更新日期:2014-06-01 00:00:00

  • The detection of platelet antibodies using a modified platelet immunofluorescence test.

    abstract::The development of sensitive immunofluorescent technics for the detection of platelet antibodies has stimulated renewed interest in the field of platelet immunology. However, the analysis of multispecific sera containing both HLA and platelet-specific antibodies requires cumbersome absorption technics and relatively l...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/80.6.839

    authors: Boisvert A,MacPherson BR

    更新日期:1983-12-01 00:00:00

  • Nonuniform distribution of occult blood in feces.

    abstract::Inhibition of anti-Rh29 by erythrocytic stroma in feces was devised as a specific test for fecal occult blood. The sensitivity of this test was equivalent to that of a standard Hemoccult test, namely, 10(8) erythrocytes/g feces. Comparison of results of this test with results of Hemoccult tests of random stool specime...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/71.2.204

    authors: Rosenfield RE,Kochwa S,Kaczera Z,Maimon J

    更新日期:1979-02-01 00:00:00

  • Cellular dyscohesion in fine-needle aspiration of breast carcinoma. Prognostic indicator for axillary lymph node metastases?

    abstract::The role of fine-needle aspiration (FNA) in the diagnosis of breast carcinoma is established. We evaluated whether the degree of cellular dyscohesion and the nuclear grade in FNA material of breast carcinomas are reliable prognostic predictors for ipsilateral axillary lymph node metastasis. FNA specimens from 98 women...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/PR6K-7RXQ-NJUD-443Q

    authors: Schiller AB,Tadros TS,Birdsong GG,Grossl NA

    更新日期:2001-02-01 00:00:00

  • Evaluation of HPV-16 and HPV-18 genotyping for the triage of women with high-risk HPV+ cytology-negative results.

    abstract::The ATHENA (Addressing THE Need for Advanced HPV Diagnostics) HPV study evaluated the clinical usefulness of the cobas HPV Test (Roche Molecular Systems, Pleasanton, CA) for high-risk human papillomavirus (HR-HPV) testing (14 HR types) and individual HPV-16/HPV-18 genotyping in women undergoing routine cervical cytolo...

    journal_title:American journal of clinical pathology

    pub_type: 临床试验,杂志文章

    doi:10.1309/AJCPTUS5EXAS6DKZ

    authors: Wright TC Jr,Stoler MH,Sharma A,Zhang G,Behrens C,Wright TL,ATHENA (Addressing THE Need for Advanced HPV Diagnostics) Study Group.

    更新日期:2011-10-01 00:00:00

  • Measuring errors in surgical pathology in real-life practice: defining what does and does not matter.

    abstract::This review summarizes our experience using blinded review as a method to measure quality in surgical pathology. It details the specifics about how the review is performed, the weaknesses in the method, and then summarizes our results so far. These results suggest that error rates correlate with the individual patholo...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:10.1309/5KF89P63F4F6EUHB

    authors: Renshaw AA,Gould EW

    更新日期:2007-01-01 00:00:00

  • Tests for departure from normal in laboratory data.

    abstract::This study was undertaken to compare several methods of evaluating the common assumption that laboratory data may be treated as if they had been drawn from an underlying Gaussian distribution. As had been described earlier, the usual Kolmogorov-Smirnov test was found to be unsatisfactory due to its sensitivity to roun...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/83.5.642

    authors: Rossing RG,Hillis A,Chou DY

    更新日期:1985-05-01 00:00:00

  • Performance Evaluation of Serum Free Light Chain Analysis: Nephelometry vs Turbidimetry, Monoclonal vs Polyclonal Reagents.

    abstract:Objectives:Free light chain (FLC) measurement gained a lot of interest for diagnostic workup of monoclonal gammopathy. Methods:We evaluated the performance of turbidimetric polyclonal Freelite (The Binding Site, Birmingham, UK) assays on Cobas 6000 (Roche Diagnostics, Rotkreuz, Switzerland) and nephelometric monoclona...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/aqx037

    authors: Messiaen AS,De Sloovere MMW,Claus PE,Vercammen M,Van Hoovels L,Heylen O,Debrabandere J,Vanpoucke H,De Smet D

    更新日期:2017-06-01 00:00:00

  • Fixation time does not affect expression of HER2/neu: a pilot study.

    abstract::It is said that HER2/neu expression by immunohistochemical analysis varies with the time of fixation. The purpose of this pilot study was to determine the impact of the length of fixation in 10% buffered formalin on the expression of HER2/neu by immunohistochemical analysis. We studied tissue samples from 10 invasive ...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/AJCPAIJPSN4A9MJI

    authors: Ibarra JA,Rogers LW

    更新日期:2010-10-01 00:00:00

  • Hematogones in the bone marrow of adults. Immunophenotypic features, clinical settings, and differential diagnosis.

    abstract::Hematogones (HGs) comprise a B-lineage lymphoid precursor cell population in the bone marrow (BM) that may simulate acute lymphoblastic leukemia or lymphoma. Increased numbers of HGs have been noted in children, but few reports describe their occurrence in adults. We identified 13 adult patients with significant numbe...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/102.2.202

    authors: Davis RE,Longacre TA,Cornbleet PJ

    更新日期:1994-08-01 00:00:00

  • Studies of end-stage kidneys. III. Glycogen deposition in interstitial cells of the renal medulla.

    abstract::Examination of kidneys of ten patients with uremia and severe hypertension treated by chronic intermittent hemodialysis revealed a deposition of glycogen within interstitial cells of the renal medulla. This is unlike any described renal distribution of glycogen. Electron microscopic studies performed in one case demon...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/72.3.400

    authors: Hughson MD,McManus JF,Fitts CT,Williams AV

    更新日期:1979-09-01 00:00:00

  • Theory and applications of the polymerase chain reaction.

    abstract::The polymerase chain reaction (PCR) is a newly developed molecular biology technique that can significantly amplify DNA or RNA. The process consists of repetitive cycles of specific DNA synthesis, defined by short stretches of preselected DNA. With each cycle, there is a doubling of the final, desired DNA product such...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:

    authors: Remick DG,Kunkel SL,Holbrook EA,Hanson CA

    更新日期:1990-04-01 00:00:00

  • Comparison of eight kits for the diagnosis of pregnancy.

    abstract::The results obtained with eight pregnancy kits on 735 urines were compared. Overall accuracies were similar and fairly high (93.4 to 95.37%), although only 78.28% of all pregnancies were simultaneously detected by all eight kits. It is suggested that the different performances of each kit could be accounted for not on...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/64.4.452

    authors: Porres JM,D'Ambra C,Lord D,Garrity F

    更新日期:1975-10-01 00:00:00

  • Frequent gains of the short arm of chromosome 9 in multiple myeloma with normal G-banded karyotype detected by comparative genomic hybridization.

    abstract::A number of genetic abnormalities have been detected in multiple myeloma (MM) using cytogenetic techniques. The prominent abnormalities are deletions of 13q and translocations affecting the IgH locus on 14q32. The recurrence of chromosomal abnormalities in MM suggests a specific role for them concerning its pathogenes...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1309/5KWK-P6UK-GNXX-HMYH

    authors: Tchinda J,Volpert S,Kropff M,Berdel WE,Kienast J,Meinhardt F,Horst J

    更新日期:2004-12-01 00:00:00

  • Paratesticular multicystic mass of Wolffian, probably paradidymal, origin.

    abstract::A unilateral multicystic mass in the connective tissue adjacent to the vas deferens in a 46-year-old man is reported. Anatomically, it was distinct from the epididymis and vas and contained no sperm. The epithelial lining was simple, ciliated, and cuboidal to columnar. The cysts were surrounded by connective tissue co...

    journal_title:American journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1093/ajcp/101.4.543

    authors: Schned AR,Seremetis GM,Rous SN

    更新日期:1994-04-01 00:00:00