Nonuniform distribution of occult blood in feces.

Abstract:

:Inhibition of anti-Rh29 by erythrocytic stroma in feces was devised as a specific test for fecal occult blood. The sensitivity of this test was equivalent to that of a standard Hemoccult test, namely, 10(8) erythrocytes/g feces. Comparison of results of this test with results of Hemoccult tests of random stool specimens and of stools following ingestion of autologous blood revealed nonuniform distribution of occult blood in feces. The extent of nonuniformity was determined by testing samples of stool specimens following ingestion of 51Cr-labeled autologous blood. This allowed comparison of Hemoccult, inhibition of anti-Rh, and radioactivity, and showed that the three labels could separate in the feces and that some single small samples of feces could be relatively free of blood while blood was readily demonstrable in other portions. The variability of standard Hemoccult test was somewhat reduced by dispersing the feces in distilled water before performing the test.

journal_name

Am J Clin Pathol

authors

Rosenfield RE,Kochwa S,Kaczera Z,Maimon J

doi

10.1093/ajcp/71.2.204

subject

Has Abstract

pub_date

1979-02-01 00:00:00

pages

204-9

issue

2

eissn

0002-9173

issn

1943-7722

journal_volume

71

pub_type

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