Tests for departure from normal in laboratory data.

abstract：:Using digital cell image analysis performed on Feulgen-stained nuclei, the nuclear characteristics of prostatic neoplasia, ranging from benign (benign prostatic hyperplasia [BPH]), through dysplastic (prostatic intraepithelial neoplasia [PIN] 1-3), to carcinoma were studied. Four histopathologic groups were studied: g...

journal_title：American journal of clinical pathology

authors： Petein M,Michel P,van Velthoven R,Pasteels JL,Brawer MK,Davis JR,Nagle RB,Kiss R

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVES:Endocervical curettage (ECC) specimens may be limited by scant tissue. We evaluated whether a cellular concentration processing method could improve their diagnostic quality. METHODS:Between October 2018 and June 2019, ECC specimens were assigned chronologically to one of two groups: nonconcentrated ECC (NE...

journal_title：American journal of clinical pathology

authors： Ramia de Cap M,Jou D,Chen Y,Hecht JL,VanderLaan PA,Chen AL

更新日期：2021-01-04 00:00:00

abstract：OBJECTIVES:MDM2 gene amplification is associated with well-differentiated (WDL) and dedifferentiated liposarcomas (DDL). Using fluorescent in situ hybridization (FISH), we sought to characterize various patterns of MDM2 amplification among the morphologic spectrum of liposarcoma. METHODS:Forty-six cases of liposarcoma...

journal_title：American journal of clinical pathology

authors： Ware PL,Snow AN,Gvalani M,Pettenati MJ,Qasem SA

更新日期：2014-03-01 00:00:00

abstract：:Cardiac-related death has been reported following strenuous exercise, and biochemical markers predicting adverse outcomes would be useful. Despite the fact the myeloperoxidase (MPO) release may precede myocardial injury and identify at-risk patients earlier than traditional markers, information on the effects of marat...

journal_title：American journal of clinical pathology

authors： Melanson SE,Green SM,Wood MJ,Neilan TG,Lewandrowski EL

更新日期：2006-12-01 00:00:00

abstract：:A prototype food-bound vitamin B12 (food-B12) absorption test has been developed in which 57Co-B12 was incorporated in vitro into egg yolk (yolk-B12) and served to volunteers in 50-g cooked portions together with toast and coffee for breakfast. Six hours later, 1 mg nonlabeled B12 was given intramuscularly and 24-hour...

journal_title：American journal of clinical pathology

authors： Doscherholmen A,Silvis S,McMahon J

更新日期：1983-10-01 00:00:00

abstract：:A patient with an acute burn was noticed to have spuriously elevated platelet counts on an automated system. The major factor accounting for this discrepancy was the presence of numerous microspherocytes which were in the same size range of platelets. It is thus important to add microspherocytosis as an additional cau...

journal_title：American journal of clinical pathology

authors： Akwari AM,Ross DW,Stass SA

更新日期：1982-02-01 00:00:00

abstract：:Soft-agar culture of transitional cell carcinoma colonies from urine, bladder irrigation fluid, and transurethral resection solid tumor specimens demonstrate generally better growth of tumor cell colonies from urine than from irrigation fluid. Growth of tumor colonies from urine was adequate to evaluate presence of tu...

journal_title：American journal of clinical pathology

authors： Kirkels WJ,Pelgrim OE,Debruyne FM,Vooijs GP,Herman CJ

更新日期：1982-11-01 00:00:00

abstract：:Three anti-Factor-VIII antibodies from hemophiliacs were reacted with samples of batches of Maws commerical bovine and porcine Factor VIII concentrates manufactured over a 12-year period. The apparent antibody concentrations varied widely with the different batches of concentrates. The variations are probably due to i...

journal_title：American journal of clinical pathology

authors： Edson JR,Swinehart CD

更新日期：1976-06-01 00:00:00

abstract：:The resources needed to operate a clinical chemistry laboratory are known only as rough approximations. In order to gather more information about these resources, a 13-page questionnaire was completed by 50 pathology departments of which 38 departments provided adequate information about their clinical chemistry secti...

journal_title：American journal of clinical pathology

authors： Elin RJ,Robertson EA,Sever G

更新日期：1982-12-01 00:00:00

abstract：:Nineteen patients with acute nonlymphocytic leukemia were found to have a pericentric inversion of chromosome 16. All were classified as having acute myelomonocytic leukemia (M4) according to French-American-British Cooperative Group (FAB) criteria. Consistent abnormalities of marrow eosinophils were present. In 15 of...

journal_title：American journal of clinical pathology

authors： Bitter MA,Le Beau MM,Larson RA,Rosner MC,Golomb HM,Rowley JD,Vardiman JW

更新日期：1984-06-01 00:00:00

abstract：:Cellular proliferation is being evaluated as an independent prognostic indicator in a variety of tumors, including non-Hodgkin's lymphomas (NHL). Although the labeling index (LI), using either tritiated thymidine or monoclonal antibodies to bromodeoxyuridine, is considered to be the gold standard of cell kinetic measu...

journal_title：American journal of clinical pathology

authors： Sebo TJ,Roche PC,Witzig TE,Kurtin PJ

更新日期：1993-06-01 00:00:00

abstract：:The radioimmunoassay of ACTH was used in a routine laboratory to localize the site of the lesion in 20 patients with Cushing's syndrome. Eight of the patients had no detectable circulating ACTH and had adrenal tumors removed, 12 had high levels and were diagnosed as having pituitary Cushing's syndrome. Very high level...

journal_title：American journal of clinical pathology

authors： Broughton A

更新日期：1975-11-01 00:00:00

abstract：:A 63-year-old white man had simultaneous onset of the Guillain-Barré syndrome and the nephrotic syndrome, three weeks after having an upper respiratory tract infection. Many granular casts were noticed in the urine sediment. Renal biopsy specimens showed early membranous glomerulonephritis and acute interstitial nephr...

journal_title：American journal of clinical pathology

authors： Talamo TS,Borochovitz D

更新日期：1982-10-01 00:00:00

abstract：:The diagnostic expert system for colonic lesions (DESCL) was designed to discriminate colonic adenoma and adenocarcinoma from normal colonic tissue. Although it was originally developed for use in conjunction with a machine vision analytic system, the DESCL has evolved into a teaching tool and a model for conceptual m...

journal_title：American journal of clinical pathology

authors： Graham AR,Paplanus SH,Bartels PH

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVES:To determine the impact of implementing p16 Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions (LAST) guidelines, we compared p16 use and follow-up data before and after implementation of the guidelines. METHODS:We reviewed all cervical biopsy specimens diagnosed by two...

journal_title：American journal of clinical pathology

authors： Clinton LK,Miyazaki K,Ayabe A,Davis J,Tauchi-Nishi P,Shimizu D

更新日期：2015-12-01 00:00:00

abstract：Objectives:To model renal function 2 years following radical nephrectomy with quantitative analyses using clinical, histopathologic, and renal composite cortical volumes (CCV). Methods:This retrospective study involved an assessment of the nonneoplastic kidney tissue by three blinded nephropathologists using modified ...

journal_title：American journal of clinical pathology

authors： Pruthi DK,Oomah S,Lu V,Ting T,Knickle C,Liss MA,Gibson IW,Kirkpatrick IDC,McGregor TB

更新日期：2019-01-01 00:00:00

abstract：:Non-Hodgkin lymphoma (NHL) is more likely to develop in patients with Hodgkin disease (HD) than in the general population. Although reports of synchronous or metachronous HD and NHL are not uncommon in the literature, the biologic relationship of these 2 malignant neoplasms often is unclear. A larger-than-expected fra...

journal_title：American journal of clinical pathology

authors： Brown JR,Weng AP,Freedman AS

更新日期：2004-05-01 00:00:00

abstract：:A series of 138 patients seen consecutively in an adult allergy clinic were studied to determine serum alpha1-antitrypsin (alpha1-AT) levels and protease inhibitor (Pi) phenotypes. These were compared with a control group of 700 healthy young adult blood donors. Both total serum trypsin inhibitory capacity (STIC) and ...

journal_title：American journal of clinical pathology

authors： Ihrig J,Schwartz HJ,Rynbrandt DJ,Kleinerman J

更新日期：1975-09-01 00:00:00

abstract：Objectives:Hemolyzed blood samples commonly occur in hospital emergency departments (EDs). Our objective was to determine whether replacing standard large-volume/high-vacuum sample tubes with low-volume/low-vacuum tubes would significantly affect ED hemolysis. Methods:This was a prospective intervention of the use of ...

journal_title：American journal of clinical pathology

authors： Phelan MP,Reineks EZ,Berriochoa JP,Schold JD,Hustey FM,Chamberlin J,Kovach A

更新日期：2017-10-01 00:00:00

abstract：:Specific esterase activity, a property generally ascribed to cells of granulocytic origin, was found in abnormal erythroid precursors obtained from the bone marrows of six patients with untreated erythroleukemia. These erythroblasts also showed nonspecific esterase activity. Neither specific nor nonspecific esterase a...

journal_title：American journal of clinical pathology

authors： Kass L

更新日期：1977-04-01 00:00:00

abstract：OBJECTIVES:Meningiomas usually can be readily diagnosed on H&E alone, although occasionally immunohistochemistry (IHC) confirmation is desirable. Studies exploring the diagnostic utility of either podoplanin (D2-40) or E-cadherin IHC in meningiomas have conflicted, and no studies exist in which the two IHCs have been u...

journal_title：American journal of clinical pathology

authors： Mrachek EK,Davis D,Kleinschmidt-DeMasters BK

更新日期：2015-12-01 00:00:00

abstract：:The determination of tumor cell estrogen receptor (ER) expression status by immunohistochemical analysis has become standard practice, yet assay reproducibility has not been assessed adequately. By using a breast cancer tissue microarray, we examined interlaboratory variability in ER reporting. A 2-fold redundant tiss...

journal_title：American journal of clinical pathology

authors： Parker RL,Huntsman DG,Lesack DW,Cupples JB,Grant DR,Akbari M,Gilks CB

更新日期：2002-05-01 00:00:00

abstract：:To increase transplantation access, particularly in living-donor renal transplantation, efforts have been made to overcome the barrier of ABO incompatibility. In adults, the most successful cases have involved renal transplantation. Although the overall goal of reducing antibodies against donor ABO before and after tr...

journal_title：American journal of clinical pathology

authors： Warner PR,Nester TA

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVES:Solid tumor metastases to the pancreas are rare, and only limited literature on the topic is available. In this retrospective study, we reviewed 107 cases of solid tumor metastases to the pancreas diagnosed by fine-needle aspiration (FNA) from 2005 to 2019. METHODS:Information including the patients' clinic...

journal_title：American journal of clinical pathology

authors： Hou T,Stewart JM,Lee JH,Gan Q

更新日期：2020-10-13 00:00:00

abstract：:Serum bicarbonate testing has been reported to be inaccurate in several clinical studies. This prompted a search for systemic errors in bicarbonate testing devices, which has been inconclusive. The effect on serum bicarbonate level measurement of partially filling plain red-top (clot) vacutainer tubes was studied in h...

journal_title：American journal of clinical pathology

authors： Herr RD,Swanson T

更新日期：1992-02-01 00:00:00

abstract：:Double immunostaining of tissue sections by monoclonal antibodies has been performed using, in immunofluorescence, combinations of reagents conjugated with different fluorochromes. These were monoclonal antibodies directly labeled with phycoerythrin (a new red fluorochrome) and haptenated monoclonal antibodies detecte...

journal_title：American journal of clinical pathology

authors： Pizzolo G,Chilosi M

更新日期：1984-07-01 00:00:00

abstract：:The ability of the cervical Papanicolaou (Pap) smear to detect cervicitis associated with Chlamydia trachomatis was investigated. Cultures and cervical cytology samples were obtained from 487 women seen at the Mayo Clinic Department of Obstetrics and Gynecology and at the Sexually Transmitted Disease clinic of the Olm...

journal_title：American journal of clinical pathology

authors： Dorman SA,Danos LM,Wilson DJ,Noller KL,Malkasian GD,Goellner JR,Smith TF

更新日期：1983-04-01 00:00:00

abstract：:The authors investigated assays for free protein S (ProS) antigen, total ProS antigen, and ProS crossed immunoelectrophoresis (CIEP) in the diagnosis of type 1 inherited ProS deficiency. Accurate measurement of the hemostatically important free ProS required showing that, on each specimen, precipitation of the C4b-bin...

journal_title：American journal of clinical pathology

authors： Edson JR,Vogt JM,Huesman DA

更新日期：1990-08-01 00:00:00

abstract：:The performance of the Coulter STKS (Coulter, Hialeah, FL) was evaluated in a busy computerized teaching hospital laboratory. The STKS was compared with a Coulter S Plus IV and manually performed 400 white blood-cell differentials. The measured blood-count parameters (i.e., white blood cells [WBCs], red blood cells [R...

journal_title：American journal of clinical pathology

authors： Warner BA,Reardon DM

更新日期：1991-02-01 00:00:00

abstract：OBJECTIVES:We report a case of a patient with diabetes mellitus and unexpectedly low hemoglobin A1c results associated with paroxysmal nocturnal hemoglobinuria (PNH). We review the impact of shortened RBC half-life on the interpretation of hemoglobin A1c levels. METHODS:Patient history and laboratory test results were...

journal_title：American journal of clinical pathology

authors： Xia D,McShine R,Berg AH

更新日期：2014-08-01 00:00:00