Dual isotope Schilling test for measuring absorption of food-bound and free vitamin B12 simultaneously.

abstract：:Statin is a 57 kDa nuclear protein exclusively found in noncycling cells. Its expression in hematolymphoid cells had not been examined previously. The authors studied statin immunoreactivity in nonneoplastic lymphoid tissues from 26 lymph nodes, 3 tonsils, and 2 spleens. Statin was detected primarily in small lymphoid...

journal_title：American journal of clinical pathology

authors： Trudel MA,Oligny L,Caplan S,Caplan C,Schipper HM,Wang E

更新日期：1994-04-01 00:00:00

abstract：:Although red blood cell (RBC) antigen typing by agglutination is generally useful, several situations exist where this approach is difficult or impossible. For example, following a massive transfusion, a patient's residual RBCs are mixed with transfused normal donor RBCs. In this case, typing by hemagglutination prima...

journal_title：American journal of clinical pathology

authors： Eshleman JR,Shakin-Eshleman SH,Church A,Kant JA,Spitalnik SL

更新日期：1995-03-01 00:00:00

abstract：:Campylobacter fetus subspecies jejuni has recently been recognized as a significant cause of enteritis in humans. The organism has been previously postulated to cause illness by direct invasion of the mucosa of the gastrointestinal tract, but this has not been documented. Reported is a case of Campylobacter enteritis ...

journal_title：American journal of clinical pathology

authors： Duffy MC,Benson JB,Rubin SJ

更新日期：1980-05-01 00:00:00

abstract：Objectives:Early and accurate diagnosis remains crucial in the therapeutic management of invasive central nervous system fungal infections. Different molds have intrinsic resistance to antifungal agents; thus, morphologic differentiation is helpful to clinicians. Methods:Using three examples, we present a guide on how...

journal_title：American journal of clinical pathology

authors： Chavez JA,Brat DJ,Hunter SB,Velazquez Vega J,Guarner J

更新日期：2018-01-29 00:00:00

abstract：:The participant performances on the College of American Pathologists (CAP) Urine Survey specimens distributed during 1979 and 1980 for pregnancy testing are reviewed. Almost all the reagent methods used by the participants performed well on the negative specimens. Prominent differences in results on the positive speci...

journal_title：American journal of clinical pathology

authors： Biesecker JL,Rippey JH

更新日期：1981-10-01 00:00:00

abstract：:The development of chemoresistance in a variety of cancers seems related to overexpression of the P-glycoprotein (P-gp) drug pump. Nephroblastoma, the most common malignant renal tumor of childhood, usually is responsive to treatment, and prognosis is favorable in most cases. However, the disease in a subset of patien...

journal_title：American journal of clinical pathology

authors： Camassei FD,Arancia G,Cianfriglia M,Bosman C,Francalanci P,Ravà L,Jenkner A,Donfrancesco A,Boldrini R

更新日期：2002-03-01 00:00:00

abstract：:Chronic lymphocytic leukemia (CLL) is well characterized clinically and immunophenotypically. Demonstration of a monotypic CD19+, CD5+ B-cell population is central to the diagnosis. We report 2 cases of biclonal CLL. Two elderly men were encountered with an absolute lymphocytosis consisting of the typical CD5+, CD19+,...

journal_title：American journal of clinical pathology

authors： Hsi ED,Hoeltge G,Tubbs RR

更新日期：2000-06-01 00:00:00

abstract：:Pretreatment posterior iliac crest bone marrow biopsies were obtained from 26 multiple myeloma patients. Biopsies were processed in methacrylate. The percentage of myeloma tissue, myeloid tissue, and fat was estimated in each biopsy. In 20 patients who died there was a positive correlation between the percent of myelo...

journal_title：American journal of clinical pathology

authors： Mahmoud LA,Block MH,Franks JJ,Sayed NM

更新日期：1983-09-01 00:00:00

abstract：:The prognostic value of DNA ploidy and proliferative index (PI) are well established in many cancers, but their significance in childhood rhabdomyosarcoma (RMS) is unclear. We studied the DNA content and PI of 45 cases of childhood RMS obtained retrospectively. DNA histograms were hyperdiploid in 30 cases (67%), diplo...

journal_title：American journal of clinical pathology

authors： San Miguel-Fraile P,Carrillo-Gijón R,Rodriguez-Peralto JL,Badiola IA

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVES:To describe four cases of an uncommon type of acalculous cholecystitis/cholangitis characterized by increased intraepithelial lymphocytes within the biliary epithelium. METHODS:Cases were prospectively compiled during regular surgical pathology sign-out. Clinical information was obtained from the electronic...

journal_title：American journal of clinical pathology

authors： Jessurun J

更新日期：2015-01-01 00:00:00

abstract：:Immunophenotypic analysis of acute leukemias is time consuming and often requires flow cytometric analysis. A 1-hour alkaline phosphatase-labeled streptavidin-biotin immunocytochemical procedure was evaluated as an alternative. Seventeen cases of acute leukemia, including 10 acute lymphocytic (ALL) and 7 acute nonlymp...

journal_title：American journal of clinical pathology

authors： Hammer RD,Collins RD,Ebrahimi S,Casey TT

更新日期：1992-06-01 00:00:00

abstract：:The nephrotic syndrome has long been recognized as a hypercoagulable state. Arterial thrombosis is a rare complication of the syndrome. Diuretics and steroids, standard treatment for exacerbations, have been implicated as contributing to the development of arterial thrombosis. The authors present the pathologic, clini...

journal_title：American journal of clinical pathology

authors： Zimmerman RL,Novek S,Chen JT,Roggli V

更新日期：1994-02-01 00:00:00

abstract：:In the differential diagnosis of Spitz nevus vs malignant melanoma, patient age provides a critical piece of clinical information, because Spitz nevi occur mostly in children and melanomas occur mostly in adults. Nevertheless, there is overlap in the age distributions of Spitz nevus and melanoma. The issue to consider...

journal_title：American journal of clinical pathology

authors： Vollmer RT

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVES:Preanalytical factors, such as hemolysis, affect many components of a test panel. Machine learning can be used to recognize these patterns, alerting clinicians and laboratories to potentially erroneous results. In particular, machine learning might identify which cases of elevated potassium from a point-of-c...

journal_title：American journal of clinical pathology

authors： Benirschke RC,Gniadek TJ

更新日期：2020-07-07 00:00:00

abstract：:We compared the anti-estrogen receptors (ER) SP1, 6F11, and 1D5 antibodies in breast carcinoma cases with different ranges of positive cells to evaluate whether this could generate different therapies for patients. We selected 66 cases of breast cancer, each of which was immunostained with the 3 antibodies. 1D5 was le...

journal_title：American journal of clinical pathology

authors： Bogina G,Zamboni G,Sapino A,Bortesi L,Marconi M,Lunardi G,Coati F,Massocco A,Molinaro L,Pegoraro C,Venturini M

更新日期：2012-11-01 00:00:00

abstract：:A 49-year-old diabetic woman developed polymicrobial anaerobic meningitis secondary to a meningorectal fistula one year after receiving neutron beam therapy for a rectal adenocarcinoma. The meningitis was refractory to chloramphenicol and penicillin but responded to oral metronidazole. Sustained eradication of meningi...

journal_title：American journal of clinical pathology

authors： Walsh TJ,Weinstein RA,Malinoff H,Breyer MD,Berelowitz BA

更新日期：1982-07-01 00:00:00

abstract：OBJECTIVES:Overuse of laboratory tests is a persistent issue. We examined the use and overuse of serum immunofixation electrophoresis and serum free light chain assays to develop an algorithm for optimizing utilization. METHODS:A retrospective review of all tests, for investigation of monoclonal gammopathies, for all ...

journal_title：American journal of clinical pathology

authors： Heaton C,Vyas SG,Singh G

更新日期：2016-04-01 00:00:00

abstract：:Bordetella pertussis (Bp) infection in infants and young children can be associated with a significant increase in small lymphocytes with convoluted and cleaved nuclei (SLCCN) in the peripheral blood (PB). Buffy coat smears were studied that were prepared from the PB of 11 children with documented Bp infection, whose ...

journal_title：American journal of clinical pathology

authors： Kubic VL,Kubic PT,Brunning RD

更新日期：1991-06-01 00:00:00

abstract：:The resources needed to operate a clinical chemistry laboratory are known only as rough approximations. In order to gather more information about these resources, a 13-page questionnaire was completed by 50 pathology departments of which 38 departments provided adequate information about their clinical chemistry secti...

journal_title：American journal of clinical pathology

authors： Elin RJ,Robertson EA,Sever G

更新日期：1982-12-01 00:00:00

abstract：:Percent-free prostate-specific antigen (proportion of free prostate-specific antigen [PSA] to total PSA) has been shown recently in studies on frozen serum samples to be more useful than total PSA alone in distinguishing prostate cancer from benign conditions of the prostate gland. The primary purpose of our study was...

journal_title：American journal of clinical pathology

authors： Henricks WH,England BG,Giacherio DA,Oesterling JE,Wojno KJ

更新日期：1998-05-01 00:00:00

abstract：:A series of 127 renal specimens reflecting a wide spectrum of renal pathology was evaluated with a direct immunoperoxidase technic in which frozen tissue was first reacted with anti-Ig(G,A,M) and anti-C3-peroxidase conjugates and subsequently counterstained with periodic acid-Schiff-hematoxylin (IMPAS). This technic p...

journal_title：American journal of clinical pathology

authors： Tubbs RR,Gephardt G,Valenzuela R,Deodhar S

更新日期：1980-02-01 00:00:00

abstract：OBJECTIVES:The 2014 Bethesda System (TBS 2014) guidelines for reporting cervical cytology revised the age for reporting benign endometrial cells (BECs) from 40 years or older to age 45 years or older. We evaluated this change and further investigated if extending the reporting age to 50 years or older may be acceptable...

journal_title：American journal of clinical pathology

authors： Hernandez A,Schatz-Siemers N,Zhou F,Brandler TC,Negron R,Modi L,Elgert PA,Simsir A

更新日期：2020-08-05 00:00:00

abstract：:The combined experience of four university medical centers with fine-needle aspiration biopsy (FNAB) of the mediastinum is reviewed. This series includes 189 cases, with 100 males and 89 females, 6 months to 86 years of age. The majority (71%) of diagnoses were neoplastic with the remainder equally distributed between...

journal_title：American journal of clinical pathology

authors： Powers CN,Silverman JF,Geisinger KR,Frable WJ

更新日期：1996-02-01 00:00:00

abstract：:Quantitative measurements of constituent concentrations of Survey specimens are generally recorded to the nearest integer or to the nearest tenth. Questions have arisen as to whether this degree of rounding of measurements is appropriate when available laboratory equipment can determine results more precisely. Statist...

journal_title：American journal of clinical pathology

authors： Williams GW,Schork MA

更新日期：1976-07-01 00:00:00

abstract：:By studying more than 1,200 patients with cutaneous melanoma and long-term follow-up, I examined the relationship between solar elastosis and age at diagnosis of melanoma, key features of melanoma, and the outcome of overall survival in melanoma. I found that melanomas with elastosis were diagnosed significantly later...

journal_title：American journal of clinical pathology

authors： Vollmer RT

更新日期：2007-08-01 00:00:00

abstract：:A markedly prolonged activated partial thromboplastin time (APTT) was observed in a 61-year-old woman with bruising and a decreasing hematocrit. Coagulation laboratory evaluation was sought to determine the cause of the prolonged APTT and bleeding. Evaluation demonstrated that, rather than identifying a coagulopathy, ...

journal_title：American journal of clinical pathology

authors： Humphries JE,Acker MN,Schnell DE,Knarr JW

更新日期：1993-08-01 00:00:00

abstract：:A case of metastatic squamous cell carcinoma to bone was studied using immunoperoxidase methods for Factor VIII-related antigen, producing positive staining in the tumor cells. Electron microscopy proved the squamous nature of the tumor, and, subsequently, a pulmonary primary tumor was found. Testing of additional tum...

journal_title：American journal of clinical pathology

authors： Wilson AJ

更新日期：1984-01-01 00:00:00

abstract：:We describe 2 male patients in whom hepatosplenic gamma/delta T-cell lymphoma (HSTL) developed 6 and 10 years after renal transplantation. The onset was abrupt with systemic symptoms, cytopenia, and hepatosplenomegaly. The histologic examination of the spleen (case 1), liver, and bone marrow revealed sinusoidal infilt...

journal_title：American journal of clinical pathology

authors： Khan WA,Yu L,Eisenbrey AB,Crisan D,al Saadi A,Davis BH,Hankin RC,Mattson JC

更新日期：2001-07-01 00:00:00

abstract：:The authors studied the effect of averaging replicated assays of Factor IX coagulation activity and Factor IX antigen on each plasma specimen in improving the ability to detect carriers of hemophilia B. The improvement resulting from this procedure is particularly marked in tests depending on the linear regression of ...

journal_title：American journal of clinical pathology

authors： Lipworth L,Tiarks CY,Rice CA,Pechet L

更新日期：1979-12-01 00:00:00

abstract：:In today's environment, many laboratories and pathology practices are challenged to maintain or increase their quality while simultaneously lowering their overall costs. The cost of improving specimen processes is related to quality, and we demonstrate that actual costs can be reduced by designing "quality at the sour...

journal_title：American journal of clinical pathology

authors： Carlson RO,Amirahmadi F,Hernandez JS

更新日期：2012-09-01 00:00:00