Biclonal chronic lymphocytic leukemia.

abstract：:Platelet function testing is important for the diagnostic evaluation of common and rare bleeding disorders. Our study goals were to promote best practices and reduce unnecessary testing variances by developing North American guidelines on platelet function testing. Guidelines were developed by consensus for expert rec...

journal_title：American journal of clinical pathology

authors： Hayward CP,Moffat KA,Raby A,Israels S,Plumhoff E,Flynn G,Zehnder JL

更新日期：2010-12-01 00:00:00

abstract：:The cases of three patients who had clinical courses and hematologic data consistent with plasma-cell leukemia or a terminal leukemic phase of multiple myeloma are presented. A double Bence Jones protein was demonstrated in the urine of two of the patients. Immunoelectrophoresis and immunofluorescence studies demonstr...

journal_title：American journal of clinical pathology

authors： Pedraza MA

更新日期：1975-09-01 00:00:00

abstract：:Results of a comparison of the diagnostic efficacy of percutaneous needle biopsy of the parietal pleura with that of cytologic examination of pleural fluid sediment obtained concurrently from 166 patients with benign or cancerous pleural disorders are reported. Of 44 patients with confirmatory evidence of cancer invol...

journal_title：American journal of clinical pathology

authors： Frist B,Kahan AV,Koss LG

更新日期：1979-07-01 00:00:00

abstract：Objectives:To evaluate the prognostic values of microRNAs (miRNAs) in glioblastoma, and to see if there is an association between miRNAs and MGMT promoter methylation status. Methods:We collected paraffin blocks from resection specimens from 114 glioblastoma patients who had received temozolomide treatment and radioth...

journal_title：American journal of clinical pathology

authors： Chen YY,Ho HL,Lin SC,Ho TD,Hsu CY

更新日期：2018-03-29 00:00:00

abstract：:We noticed almost routine disparate results in margin lengths when colorectal specimens are measured in vivo by the surgeon and in vitro by the pathologist. We studied 26 sigmoid and rectum specimens to document the amount of organ shrinkage after surgical removal and fixation. Each specimen had a 5.0-cm segment at ea...

journal_title：American journal of clinical pathology

authors： Goldstein NS,Soman A,Sacksner J

更新日期：1999-03-01 00:00:00

abstract：:Since the introduction of the triple screen, the emergence of additional analytes found to be associated with trisomy 21 pregnancies has challenged the clinical pathology and obstetric communities to determine which combination provides the best performance characteristics as a screening test. The cost, practicality, ...

journal_title：American journal of clinical pathology

authors： Baliff JP,Mooney RA

更新日期：2003-12-01 00:00:00

abstract：:The most common differentiated renal tumor of early childhood is the congenital mesoblastic neophroma. Well-differentiated forms of Wilms' tumor may present a difficult differential diagnosis from these benign neoplasms. The cases of two patients found to have well-differentiated renal neoplasms after being treated fo...

journal_title：American journal of clinical pathology

authors： Hughson MD,Hennigar GR,Othersen HB Jr

更新日期：1976-08-01 00:00:00

abstract：:The recent clinical and commercial success of anticancer antibodies such as rituximab and trastuzumab has created great interest in antibody-based therapeutics for hematopoietic malignant neoplasms and solid tumors. Given the likelihood of lower toxic effects of antibodies that target tumor cells and have limited impa...

journal_title：American journal of clinical pathology

authors： Ross JS,Gray K,Gray GS,Worland PJ,Rolfe M

更新日期：2003-04-01 00:00:00

abstract：:To our knowledge, there are no universally accepted, evidence-based guidelines for how to resolve the HER2 status of tumors demonstrating equivocal amplification. The present study was based on 17 breast core biopsy specimens demonstrating invasive carcinoma with equivocal HER2 amplification, defined as an HER2/chromo...

journal_title：American journal of clinical pathology

authors： Striebel JM,Bhargava R,Horbinski C,Surti U,Dabbs DJ

更新日期：2008-03-01 00:00:00

abstract：:Transbronchoscopic biopsies of lung (transbronchial) or bronchus (endobronchial) have a high diagnostic of yield when performed by a single expert bronchoscopist or a small group of expert bronchoscopists. This procedure's diagnostic yield was evaluated in a general hospital where biopsies are performed by a diverse g...

journal_title：American journal of clinical pathology

authors： Jenkins R,Myerowitz RL,Kavic T,Slasky S

更新日期：1979-12-01 00:00:00

abstract：:A tumor of the larynx composed of a small infiltrating and well-differentiated squamous cell carcinoma and a large polypoid sarcomatous mass showing the histologic features of the malignant giant cell tumor of soft parts (MGCT) is reported. Other types of sarcomatous components have been described with squamous cell c...

journal_title：American journal of clinical pathology

authors： Alguacil-Garcia A,Alonso A,Pettigrew NM

更新日期：1984-09-01 00:00:00

abstract：:This report describes the selective staining of lysosomes in cells of neutrophilic granulocytic origin by the azo textile dye basic blue 93. Used as a single agent aqueous stain after fixation, the dye stained lysosomes black. Stained in this way, lysosomes were sharply delimited and easily visualized. Large numbers o...

journal_title：American journal of clinical pathology

authors： Kass L

更新日期：1988-02-01 00:00:00

abstract：:A new disposable bleeding time device (Hemalet) was tested in 20 normal individuals and 11 patients with various bleeding disorders. The results were compared with those of Simplate II. The mean bleeding time for normal individuals was 5.4 +/- 1.5 (mean +/- 1 SD) minutes by Hemalet and 5.8 +/- 1.4 (mean +/- 1 SD) minu...

journal_title：American journal of clinical pathology

authors： Toomey KC,Kim HC,Kosmin M,Saidi P

更新日期：1986-05-01 00:00:00

abstract：:Endometrial vascular changes similar to atherosclerosis of toxemia of pregnancy were described and graded in 217 consecutive endometrial biopsies of known early intrauterine pregnancy. Severe vascular changes were found in 23.5% of cases. Control material consisting of endometrial biopsies of patients with known cases...

journal_title：American journal of clinical pathology

authors： Lichtig C,Korat A,Deutch M,Brandes JM

更新日期：1988-09-01 00:00:00

abstract：:Immunoperoxidase technics were used to examine the immunoglobulin content of sections of pulmonary tissue from two typical cases of lymphomatoid granulomatosis and two cases of pneumonic processes initially diagnosed as lymphomatoid granulomatosis but representing different processes on review. Both "typical" cases an...

journal_title：American journal of clinical pathology

authors： Bender BL,Jaffe R

更新日期：1980-01-01 00:00:00

abstract：:Antiphospholipid antibodies (aPLs) have been implicated in atherogenesis. We studied 344 patients with acute coronary syndromes; approximately 40% were aPL+ in 1 or more tests and 60% aPL-. In 215 patients, coronary artery disease (CAD) was angiographically documented, with 43.7% positive for aPL vs 34.9% of patients ...

journal_title：American journal of clinical pathology

authors： Greco TP,Conti-Kelly AM,Greco T Jr,Doyle R,Matsuura E,Anthony JR,Lopez LR

更新日期：2009-10-01 00:00:00

abstract：:Serum bicarbonate testing has been reported to be inaccurate in several clinical studies. This prompted a search for systemic errors in bicarbonate testing devices, which has been inconclusive. The effect on serum bicarbonate level measurement of partially filling plain red-top (clot) vacutainer tubes was studied in h...

journal_title：American journal of clinical pathology

authors： Herr RD,Swanson T

更新日期：1992-02-01 00:00:00

abstract：:We describe 41 cases of myeloid neoplasms (MNs) secondary to plasma cell myeloma (PCM). The types of MN included myelodysplastic syndrome (MDS) in 34 (82.9%), acute myeloid leukemia (AML) in 4 (9.8%), and myeloproliferative neoplasm (MPN) or MDS/MPN in 3 (7.3%) cases. The latency from treatment to diagnosis of MN rang...

journal_title：American journal of clinical pathology

authors： Reddi DM,Lu CM,Fedoriw G,Liu YC,Wang FF,Ely S,Boswell EL,Louissaint A Jr,Arcasoy MO,Goodman BK,Wang E

更新日期：2012-12-01 00:00:00

abstract：:The Leu-8 antigen is found on the surface of many hematologic cells, including many T- and B-lymphocytes. With the use of a frozen-section immunoperoxidase technic, 152 B-cell non-Hodgkin's lymphomas were examined for Leu-8 expression. Of these lymphomas, 53% expressed Leu-8. Subclassification of the lymphomas with th...

journal_title：American journal of clinical pathology

authors： Michie SA,Garcia CF,Strickler JG,Dailey MO,Rouse RV,Warnke RA

更新日期：1987-10-01 00:00:00

abstract：:Posttransplantation lymphoproliferative disorders (PT-LPDs) occurring in T-cell depleted (TCD) allogeneic bone marrow transplant recipients seem to be different from those that arise in solid organ recipients in their early development, the high incidence of extensive dissemination at presentation, and their aggressiv...

journal_title：American journal of clinical pathology

authors： Orazi A,Hromas RA,Neiman RS,Greiner TC,Lee CH,Rubin L,Haskins S,Heerema NA,Gharpure V,Abonour R,Srour EF,Cornetta K

更新日期：1997-04-01 00:00:00

abstract：:Factitious laboratory results often lead to unnecessary testing or treatment. This brief review of factitious biochemical results due to preexisting hematologic conditions focuses on the mechanisms underlying the factitious results and suggests ways to prevent them. An observant pathologist identifies these errors, in...

journal_title：American journal of clinical pathology

authors： Dalal BI,Brigden ML

更新日期：2009-02-01 00:00:00

abstract：:Fine-needle cytology (FNC) of 292 palpable orbital and eyelid tumors was performed with a 25-gauge (0.5-mm), 3-cm needle and compared with the histopathologic findings in 286 cases. Among these 286 cases, a concordant diagnosis of malignancy and type was achieved in 249 cases (87%). False positive diagnoses were made ...

journal_title：American journal of clinical pathology

authors： Zajdela A,Vielh P,Schlienger P,Haye C

更新日期：1990-01-01 00:00:00

abstract：:A ligand assay specific for cobalamin that uses mouse stomach as the source of intrinsic factor has been developed. When mouse stomach extract incubated with radiocobalamin is fractionated by gel chromatography, the radioactive complex elutes as a single peak with apparent molecular weight of 54,900. Formation of the ...

journal_title：American journal of clinical pathology

authors： Reynoso G,Tuggey R,Hansen H,Fontelo PA,Konopka S,Miller JT

更新日期：1981-06-01 00:00:00

abstract：:The thymus was the site of a true histiocytic lymphoma. Immunohistochemical demonstration of lysozyme and alpha-1-antitrypsin in the tumor cells indicated the histiocytic nature of the tumor. Five fetal and five adult thymus glands were studied for the presence and distribution of true histiocytic cells. Histiocytes w...

journal_title：American journal of clinical pathology

authors： Szporn AH,Dikman S,Jagirdar J

更新日期：1984-12-01 00:00:00

abstract：:A 26-year-old woman who had undergone orthotopic heart transplantation because of dilative cardiomyopathy received a triple-drug immunosuppressive regimen (cyclosporine A, azathioprine, and prednisolone). During her relatively frequent episodes of acute rejection, she was treated with methylprednisolone and repeated a...

journal_title：American journal of clinical pathology

authors： Kemnitz J,Cremer J,Gebel M,Uysal A,Haverich A,Georgii A

更新日期：1990-07-01 00:00:00

abstract：:We compared prothrombin times (PTs) and international normalized ratios (INRs) for blood samples drawn into plastic vs glass collection tubes. We collected 60 venous blood samples into 4.5-mL glass and 2 plastic tubes (2.7 and 3.5 mL). An additional 153 samples, including 63 from warfarin-anticoagulated patients, were...

journal_title：American journal of clinical pathology

authors： Fiebig EW,Etzell JE,Ng VL

更新日期：2005-12-01 00:00:00

abstract：:Fourteen patients treated by allogeneic bone marrow transplantation for chronic myelogenous leukemia (CML) were evaluated by the polymerase chain reaction (PCR) for bcr-abl-specific transcripts. Nine patients were transplanted in the first chronic phase, three in the second chronic phase, and two in the accelerated ph...

journal_title：American journal of clinical pathology

authors： Okamoto R,Harano H,Matsuzaki M,Motomura S,Maruta A,Kodama F,Mohri H,Okubo T

更新日期：1995-11-01 00:00:00

abstract：:Labor use ratings assigned to instruments by the Workload Recording Method (WRM) do not change with batch size or walk-away time use. The authors evaluated the effect of both on the labor use of the analyzers Paramax B6100 (Baxter Paramax, Irvine, CA) and Ektachem 700 (Eastman Kodak, Rochester, NY) by timing all worke...

journal_title：American journal of clinical pathology

authors： McClellan GA,Nipper HC,Horn MJ,Burris WD,Hodges K,Monaco S,Cox RS Jr

更新日期：1991-05-01 00:00:00

abstract：:The major histocompatibility complex probably plays a crucial role in the efficacy of the cellular immune response against virally infected cervical diseases. Therefore, the allele-specific histocompatibility-related leukocyte antigens (HLA) class I and II expression on normal (n = 10), premalignant (n = 25), and mali...

journal_title：American journal of clinical pathology

authors： Hilders CG,Houbiers JG,Krul EJ,Fleuren GJ

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:Pool testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) preserves testing resources at the risk of missing specimens through specimen dilution. METHODS:To determine whether SARS-CoV-2 specimens would be missed after 10:1 pooling, we identified 10 specimens with midrange (ie, 25-34 cycl...

journal_title：American journal of clinical pathology

authors： Procop GW,Tuohy M,Ramsey C,Rhoads DD,Rubin BP,Figler R

更新日期：2021-01-05 00:00:00