Intrinsic factor, free of R proteins, can be prepared from mouse stomach and used in a ligand assay specific for "true" cobalamin.

abstract：:To study the histogenesis of and determine the most useful markers for diagnosing anaplastic thyroid carcinoma (ATC), 32 cases, including 2 with numerous osteoclast-like cells, were stained with a battery of antibodies to epithelial (keratin, epithelial membrane antigen [EMA], carcinoembryonic antigen [CEA]), mesenchy...

journal_title：American journal of clinical pathology

authors： Ordóñez NG,El-Naggar AK,Hickey RC,Samaan NA

更新日期：1991-07-01 00:00:00

abstract：:Previous studies suggest that low prostate weight is a significant negative prognostic factor for prostate cancer. In the current study, the data for 431 men who underwent radical retropubic prostatectomy between 1990 and 1998 were analyzed for association between prostate weight and various clinical and pathologic pa...

journal_title：American journal of clinical pathology

authors： Davidson DD,Koch MO,Lin H,Jones TD,Biermann K,Cheng L

更新日期：2010-04-01 00:00:00

abstract：:The authors have developed an immunoalkaline phosphatase method and have applied it with success to the study of blood cells. They have now observed that macrophages in tissues and in serous effusions may be nonspecifically stained when immunoalkaline phosphatase methods are used. A systematic study of this endogenous...

journal_title：American journal of clinical pathology

authors： Janckila AJ,Yam LT,Li CY

更新日期：1985-10-01 00:00:00

abstract：:This study focused on women who had an abnormal Papanicolaou smear and a subsequent colposcopic examination negative for a cervical squamous intraepithelial lesion. Cervical swabs obtained during the initial colposcopic examination were analyzed for human papillomavirus (HPV) DNA, and these results were correlated wit...

journal_title：American journal of clinical pathology

authors： Nuovo GJ,Moritz J,Walsh LL,MacConnell P,Koulos J

更新日期：1992-11-01 00:00:00

abstract：:Acute exacerbations of idiopathic pulmonary fibrosis/cryptogenic fibrosing alveolitis (IPF/CFA) are rare and typically terminal events, but their relationship to underlying patterns of idiopathic interstitial pneumonias is unknown. We reviewed autopsy material from patients who died of diffuse alveolar damage in the c...

journal_title：American journal of clinical pathology

authors： Rice AJ,Wells AU,Bouros D,du Bois RM,Hansell DM,Polychronopoulos V,Vassilakis D,Kerr JR,Evans TW,Nicholson AG

更新日期：2003-05-01 00:00:00

abstract：:Hyperparathyroidism may occasionally present as a neck mass resulting from cystic change in a parathyroid adenoma. We report an unusual instance of hyperparathyroidism presenting as a palpable, but asymptomatic hyperplastic parathyroid gland cyst. We conclude that hyperplastic parathyroid glands may undergo cystic deg...

journal_title：American journal of clinical pathology

authors： Fallon MD,Haines JW,Teitelbaum SL

更新日期：1982-01-01 00:00:00

abstract：:Bordetella pertussis (Bp) infection in infants and young children can be associated with a significant increase in small lymphocytes with convoluted and cleaved nuclei (SLCCN) in the peripheral blood (PB). Buffy coat smears were studied that were prepared from the PB of 11 children with documented Bp infection, whose ...

journal_title：American journal of clinical pathology

authors： Kubic VL,Kubic PT,Brunning RD

更新日期：1991-06-01 00:00:00

abstract：:A monoclonal antibody prepared against estrogen receptor has been shown to be specific and sensitive for the detection of estrogen receptor in human breast lesions by use of immunohistochemical methods. Two hundred selected cases of primary breast carcinoma were assayed for estrogen receptor content by biochemical and...

journal_title：American journal of clinical pathology

authors： Bacus S,Flowers JL,Press MF,Bacus JW,McCarty KS Jr

更新日期：1988-09-01 00:00:00

abstract：:Neuroendocrine tumors comprise a family of neoplasms with a wide range of morphologic, functional, and behavioral characteristics. Their diagnosis depends on the recognition of characteristic morphologic features and on the presence of markers indicative of neuroendocrine differentiation. Neuroendocrine tumors can be ...

journal_title：American journal of clinical pathology

authors： DeLellis RA

更新日期：2001-06-01 00:00:00

abstract：:Timely communication of significant or unexpected findings in surgical pathology can significantly improve patient care. Although surgical pathology critical values have been published, no systematic assessment in pediatric surgical pathology has been published. We surveyed pediatric pathologists and pediatric subspec...

journal_title：American journal of clinical pathology

authors： Coffin CM,Spilker K,Lowichik A,Zhou H,Nielson K,Erickson L,Pysher TJ

更新日期：2007-12-01 00:00:00

abstract：:A new disposable bleeding time device (Hemalet) was tested in 20 normal individuals and 11 patients with various bleeding disorders. The results were compared with those of Simplate II. The mean bleeding time for normal individuals was 5.4 +/- 1.5 (mean +/- 1 SD) minutes by Hemalet and 5.8 +/- 1.4 (mean +/- 1 SD) minu...

journal_title：American journal of clinical pathology

authors： Toomey KC,Kim HC,Kosmin M,Saidi P

更新日期：1986-05-01 00:00:00

abstract：:Reported is a case of lymphoma which was preceded for nine years by an apparently reactive lymphadenopathy. Original slides of the multiple lymphoid tissue samples are reviewed, with emphasis on the gradually increasing numbers of mitoses, atypical histiocytes, and eosinophils, suggestive of malignant transformation. ...

journal_title：American journal of clinical pathology

authors： Hyland CH,Murad TM,Dismukes WE

更新日期：1977-11-01 00:00:00

abstract：:New federal regulations require review of all available negative gynecologic smears within the previous 5 years for each patient with a current high grade squamous intraepithelial lesion (HGSIL) or above. Two university hospitals retrospectively reviewed all patients who had HGSIL or above and who had prior negative s...

journal_title：American journal of clinical pathology

authors： Allen KA,Zaleski S,Cohen MB

更新日期：1994-01-01 00:00:00

abstract：:Neoplastic transformation of epithelial cell sis commonly associated with altered synthesis of mucin glycoproteins. Few studies have been performed on the correlation between MUC 1 expression and pancreatic carcinoma using immunohistochemical methods. We compared the patterns of MUC 1 expression in normal pancreatic t...

journal_title：American journal of clinical pathology

authors： Monges GM,Mathoulin-Portier MP,Acres RB,Houvenaeghel GF,Giovannini MF,Seitz JF,Bardou VJ,Payan MJ,Olive D

更新日期：1999-11-01 00:00:00

abstract：:The authors evaluated the Yellow IRIS automated urinalysis instrument (International Remote Imaging Systems, Chatsworth, CA 91311) in terms of its analytic performance as well as its ease of use. The Yellow IRIS is a system using automated intelligence microscopy (AIM), coupled with a dipstick reader and specific grav...

journal_title：American journal of clinical pathology

authors： Roe CE,Carlson DA,Daigneault RW,Statland BE

更新日期：1986-11-01 00:00:00

abstract：:The present immunoperoxidase study attempted to localize aldosterone and cortisol in formalin-fixed paraffin-embedded adrenal glands or tumors. Apparently, steroid substances are solubilized during routine tissue processing, and the cytoplasm of adrenal cortical cells is not stained by either antialdosterone or antico...

journal_title：American journal of clinical pathology

authors： Hsu SM,Raine L,Martin HF

更新日期：1981-01-01 00:00:00

abstract：:Hepatocytes with orcein-positive ground-glass cytoplasm have been shown to contain abundant hepatitis B surface antigen in the cisternae of excess smooth endoplasmic reticulum. Hepatocytes with similar cytoplasmic changes that did not react with orcein were observed in 26.5% of 49 cases of cirrhosis. These cells exhib...

journal_title：American journal of clinical pathology

authors： Gerber MA,Thung SN

更新日期：1981-04-01 00:00:00

abstract：:Actinomycosis was diagnosed in three cases by the use of thin-needle aspiration biopsy technic. Aspiration was utilized for morphologic studies and collection of material for microbiologic isolation. The critical histologic features of sulfur granules remain intact with aspiration technic. Thin-needle aspiration biops...

journal_title：American journal of clinical pathology

authors： Pollock PG,Meyers DS,Frable WJ,Valicenti JF Jr,Koontz FP,Beavert CS

更新日期：1978-07-01 00:00:00

abstract：:The lupus anticoagulant was identified in three patients. Laboratory studies gave evidence of inhibitory activity directed against phospholipid and prekallikrein. Inhibition of prekallikrein has not been reported previously. When exposed to kaolin, all three patients' plasmas failed to develop the level of fibrinolyti...

journal_title：American journal of clinical pathology

authors： Sanfelippo MJ,Drayna CJ

更新日期：1982-03-01 00:00:00

abstract：:Because of the unusual presentation of pernicious anemia in many black women, a further characterization of this disease among the different racial groups was undertaken. The following were found. (1) Black women under the age of 50 years had a significantly lower prevalence of anti-parietal cell antibody than did "Eu...

journal_title：American journal of clinical pathology

authors： Carmel R,Ozturk G,Johnson CS,Tung KS,Terasaki PI

更新日期：1981-03-01 00:00:00

abstract：:We describe 35 peripheral lymph nodes classified as mantle cell/marginal zone B-cell hyperplasia with clear cells using morphologic and immunologic findings. For the purpose of this study, we obtained clinical follow-up information and performed immunoglobulin gene rearrangement studies on paraffin sections by polymer...

journal_title：American journal of clinical pathology

authors： Hunt JP,Chan JA,Samoszuk M,Brynes RK,Hernandez AM,Bass R,Weisenburger DD,Müller-Hermelink K,Nathwani BN

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVES:Mucinous cystic neoplasm of the liver is characterized by neoplastic mucinous and/or biliary epithelium surrounded by ovarian-type stroma. Immunohistochemical studies have shown that the ovarian-type stroma expresses estrogen receptor, suggesting potential hormonal responsiveness. The molecular biology of mu...

journal_title：American journal of clinical pathology

authors： Van Treeck BJ,Lotfalla M,Czeczok TW,Mounajjed T,Moreira RK,Allende DS,Reid MD,Naini BV,Westerhoff M,Adsay NV,Kerr SE,Rizvi SH,Smoot RL,Liu Y,Davila J,Graham RP

更新日期：2020-11-04 00:00:00

abstract：:Previous studies of patients with lymphoid malignancies have suggested a relationship between survival and the presence of more than 40% hard-mirror cells in the bone marrow. This report represents the first detailed study of a patient with American Burkitt's lymphoma with numerous hand-mirror cells in the bone marrow...

journal_title：American journal of clinical pathology

authors： Schumacher HR,Rainey T,Davidson L,Simon D,Strong M,Creegan WJ,Holloway ML,Stass SA

更新日期：1978-12-01 00:00:00

abstract：:Adenomatous polyps are common neoplastic lesions of the large intestine. The risk of carcinoma increases with polyp size. Small polyps are typically totally embedded for histologic examination, but no standard method for sampling large, grossly benign polyps has been established. We reviewed grossly noninvasive adenom...

journal_title：American journal of clinical pathology

authors： Euscher ED,Niemann TH,Lucas JG,Kurokawa AM,Frankel WL

更新日期：2001-09-01 00:00:00

abstract：:The cell cycle consists of an initial growth phase (G1), DNA replication (S), a gap phase (G2), and mitosis (M), after which the cell may differentiate or enter the resting state (G0). The cycle is driven by a number of positive and negative regulatory phosphorylation and dephosphorylation events, involving protein ki...

journal_title：American journal of clinical pathology

authors： Dictor M,Ehinger M,Mertens F,Akervall J,Wennerberg J

更新日期：1999-07-01 00:00:00

abstract：:We report serum enzyme patterns in three patients with polymyositis or dermatomyositis whose cases posed potential problems in distinguishing malignancy, hepatocellular damage, and myocardial infarction from myositis. The alanine aminotransferase showed five- to 16-fold elevations. The creatine kinase MB isoenzyme and...

journal_title：American journal of clinical pathology

authors： Morton BD 3rd,Statland BE

更新日期：1980-04-01 00:00:00

abstract：:Determination of hemoglobin A1c (HbA1c) is one of the most important monitoring procedures for long-term control of diabetes mellitus. Several analytical methods have been developed for the measurement of glycohemoglobin (GHb). Those most frequently used are ion-exchange chromatography for HbA1c and affinity chromatog...

journal_title：American journal of clinical pathology

authors： Hamwi A,Schweiger CR,Veitl M,Schmid R

更新日期：1995-07-01 00:00:00

abstract：:Mantle cell lymphoma (MCL) expresses pan-B-cell antigens and is usually CD5+/CD10-/CD23-/FMC7+. In this study, we evaluated 52 patients with confirmed diagnoses of MCL and identified variant immunophenotypes in 21 patients (19/48 classical and 2/4 variant MCLs), including CD5- in 6 (12%) of 52, CD10+ in 4 (8%) of 50, ...

journal_title：American journal of clinical pathology

authors： Gao J,Peterson L,Nelson B,Goolsby C,Chen YH

更新日期：2009-11-01 00:00:00

abstract：:The greater precision in prothrombin time monitoring obtained using thromboplastins with low international sensitivity index (ISI) values are believed to result in improved patient care. The authors conducted a blinded prospective study of 84 random patients on low-intensity warfarin therapy who were monitored with ei...

journal_title：American journal of clinical pathology

authors： Brophy MT,Fiore LD,Lau J,Goodwin R,Lopez A,Deykin D

更新日期：1994-07-01 00:00:00

abstract：:The ability to inhibit the release reaction was found to correlate well with the ability to inhibit aggregation in washed human platelets exposed to antilymphocyte serum (ALS). However, the primary mechanism that contributes to ALS-induced aggregation in unwashed platelets appeared to be different from that found in w...

journal_title：American journal of clinical pathology

authors： Wang TY,Hussey CV,Hause LL,Fobian JE

更新日期：1976-05-01 00:00:00