Platelet aggregation induced by antilymphocyte serum. 2. Two modes of the aggregation mechanism.

abstract：:Patient red blood cell (RBC) index means, when used in quality control, form an independent standard that is as accurate and precise as preserved blood controls. If such patient data are routinely incorporated in intralaboratory and interlaboratory quality control programs, a substantial improvement in the present sta...

journal_title：American journal of clinical pathology

authors： Levy WC,Bull BS,Koepke JA

更新日期：1986-08-01 00:00:00

abstract：:Transketolases link the Embden-Meyerhof pathway to the pentose phosphate pathway. An influence of p-Akt on this metabolism was described. This study was performed to compare the expression of transketolase-like 1 (TKTL1) and p-Akt in glioblastoma multiforme (GBM) and other astrocytic gliomas (AGs, grades II and III). ...

journal_title：American journal of clinical pathology

authors： Völker HU,Hagemann C,Coy J,Wittig R,Sommer S,Stojic J,Haubitz I,Vince GH,Kämmerer U,Monoranu CM

更新日期：2008-07-01 00:00:00

abstract：:During a 14-year period (1959-1972), 3,600 endometrial suction biopsies were performed in the office for specific indications in selected patients. Three hundred seventy-seven biopsies (10.5%) revealed abnormal findings. Of these, 233 showed endometritis, 96 associated with necrotic decidual or placental tissue, or bo...

journal_title：American journal of clinical pathology

authors： Baitlon D,Hadley JO

更新日期：1975-01-01 00:00:00

abstract：:Immunocytochemical assays for progesterone receptor (PR) using monoclonal antirabbit PR antibodies (PR-ICA) and for estrogen receptor (ER) (ER-ICA) were compared with radioligand binding (dextran-coated charcoal [DCC]) methods for receptor determination in patients with breast cancer. Immunocytochemical staining for P...

journal_title：American journal of clinical pathology

authors： Seymour L,Meyer K,Esser J,MacPhail AP,Behr A,Bezwoda WR

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVES:The objective of this research was to determine test intervals between intraoperator case reviews to minimize the impact of recall. METHODS:Three pathologists were presented with a group of 120 slides and subsequently challenged with a study set of 120 slides after 2-week and 4-week intervals. The challenge...

journal_title：American journal of clinical pathology

authors： Campbell WS,Talmon GA,Foster KW,Baker JJ,Smith LM,Hinrichs SH

更新日期：2015-03-01 00:00:00

abstract：:Immunostaining of cell cycle-related antigens, especially Ki-67, DNA polymerase alpha, and proliferating cell nuclear antigen, has become an important method to assess the proliferative activity of tumors. These three nuclear antigens were studied by immunohistochemical analysis of cytologic smears. These smears were ...

journal_title：American journal of clinical pathology

authors： Sasano H,Miyazaki S,Nishihira T,Sawai T,Nagura H

更新日期：1992-08-01 00:00:00

abstract：:Sera from heparinized patients commonly display anodal slurring of both the alpha and beta lipoproteins when they are examined by high-resolution electrophoresis (HRE). In this study, the authors examined the effect of heparin and lipoprotein lipase on the electrophoretic migration of alpha and beta lipoproteins in se...

journal_title：American journal of clinical pathology

authors： Pearson JP,Keren DF

更新日期：1995-10-01 00:00:00

abstract：:The most common differentiated renal tumor of early childhood is the congenital mesoblastic neophroma. Well-differentiated forms of Wilms' tumor may present a difficult differential diagnosis from these benign neoplasms. The cases of two patients found to have well-differentiated renal neoplasms after being treated fo...

journal_title：American journal of clinical pathology

authors： Hughson MD,Hennigar GR,Othersen HB Jr

更新日期：1976-08-01 00:00:00

abstract：OBJECTIVES:In 2001, the University of New Mexico Hospitals implemented a rapid screening tool for the triage of suspected hantavirus cardiopulmonary syndrome based on peripheral blood smear morphology. Five criteria guided clinical decisions: thrombocytopenia, hemoconcentration, granulocytic left shift, absence of toxi...

journal_title：American journal of clinical pathology

authors： Dvorscak L,Czuchlewski DR

更新日期：2014-08-01 00:00:00

abstract：:The Digene Hybrid Capture 2 (hc2) high-risk human papillomavirus (HPV) DNA test (Digene, Gaithersburg, MD) is widely used for triage of women with atypical squamous cells of undetermined significance. Results in a "retest zone" (weakly positive tests) are repeated up to 2 times according to the Digene-recommended algo...

journal_title：American journal of clinical pathology

authors： Muldrew KL,Beqaj SH,Han J,Lum SH,Clinard V,Schultenover SJ,Tang YW

更新日期：2007-01-01 00:00:00

abstract：:We optimized fluorogenic thrombin-generation assays with regard to sample volume, calibration, analytic corrections, and activation reagents. Lower sample volumes (40 vs 80 microL) were associated with better recovery of thrombin activity, lower interference due to absorbance of light, and higher total thrombin genera...

journal_title：American journal of clinical pathology

authors： Chandler WL,Roshal M

更新日期：2009-08-01 00:00:00

abstract：:A 73-year-old man with myelodysplastic syndrome developed during the course of his illness auto-immune hemolytic anemia. The association between auto-immune hemolysis and myeloproliferative disease is extremely rare. An even more unique finding is the nature of the antibody which demonstrated single specificity agains...

journal_title：American journal of clinical pathology

authors： Sacher RA,McGinniss MM,Shashaty GG,Jacobson RJ,Rath CE

更新日期：1982-03-01 00:00:00

abstract：:A new hemolytic plate method for the functional assessment of alternative-pathway complement activity is described. The plates are easy to prepare and the method simple to perform. Analysis of 23 normal serum samples showed a mean lysis diameter of 4.1 +/- 0.2 mm (1 standard deviation). ...

journal_title：American journal of clinical pathology

authors： Fong JS,Renaud L

更新日期：1978-02-01 00:00:00

abstract：:Micropapillary lung adenocarcinoma (MPA) has been reported as an aggressive variant of adenocarcinoma, frequently manifesting at high stage with a poor prognosis. We analyzed the clinical and molecular profile of 15 primary MPAs for K-ras, EGFR, and BRAF mutations and performed fluorescence in situ hybridization for E...

journal_title：American journal of clinical pathology

authors： De Oliveira Duarte Achcar R,Nikiforova MN,Yousem SA

更新日期：2009-05-01 00:00:00

abstract：:Lean methodologies have been applied in many industries to reduce waste. We applied Lean techniques to redesign laboratory workstations with the aim of reducing the number of times employees must leave their workstations to complete their tasks. At baseline in 68 workflows (aggregates or sequence of process steps) stu...

journal_title：American journal of clinical pathology

authors： Yerian LM,Seestadt JA,Gomez ER,Marchant KK

更新日期：2012-08-01 00:00:00

abstract：:A number of reports have highlighted discrepancies between the DuPont aca and fibrometer-based methods for quantitating plasma fibrinogen levels. Although many authors have suggested that the presence of fibrin(ogen) degradation products are in some way responsible for the discrepancies, no direct test of this hypothe...

journal_title：American journal of clinical pathology

authors： Hoffman M,Greenberg CS

更新日期：1987-10-01 00:00:00

abstract：:Three cases of infantile hemangioendothelioma were immunohistochemically studied with the use of antibodies against von Willebrand factor (vWF), Ulex europaeus I lectin (UEA I), vimentin, thrombomodulin (TM), and actin, as endothelial cell (EC) markers. Because of a broad variety of histologic features, the growth pat...

journal_title：American journal of clinical pathology

authors： Yasunaga C,Sueishi K,Ohgami H,Suita S,Kawanami T

更新日期：1989-06-01 00:00:00

abstract：:The visible absorption spectra of dilutions of commercially prepared chemistry control sera closely mimic those of jaundiced amniotic fluids in cases of fetal rhesus isoimmunization. The authors have assessed the use of these materials for the quality control of net absorbance measurements at 450 nm on amniotic fluids...

journal_title：American journal of clinical pathology

authors： McDonald OL,Watts MT

更新日期：1985-10-01 00:00:00

abstract：:A series of 127 renal specimens reflecting a wide spectrum of renal pathology was evaluated with a direct immunoperoxidase technic in which frozen tissue was first reacted with anti-Ig(G,A,M) and anti-C3-peroxidase conjugates and subsequently counterstained with periodic acid-Schiff-hematoxylin (IMPAS). This technic p...

journal_title：American journal of clinical pathology

authors： Tubbs RR,Gephardt G,Valenzuela R,Deodhar S

更新日期：1980-02-01 00:00:00

abstract：:FNAB is the most important advance in the management of thyroid nodules in the past two decades. Dr Mazzaferri has said that finding a thyroid cancer in a thyroid nodule is like finding a needle in a haystack. Fine-needle aspiration biopsy is like applying a strong electromagnet to find that needle. It should be avail...

journal_title：American journal of clinical pathology

authors： Greenspan FS

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVES:To evaluate cryoprecipitate and platelet ordering practices after the implementation of real-time clinical decision support systems (CDSSs) in a computerized physician order entry (CPOE) system. METHODS:Uniform platelet and cryoprecipitate transfusion thresholds were implemented at 11 hospitals in a regiona...

journal_title：American journal of clinical pathology

authors： Collins RA,Triulzi DJ,Waters JH,Reddy V,Yazer MH

更新日期：2014-01-01 00:00:00

abstract：:Two patients with chronic myelogenous leukemia (CML) developed blast crisis that morphologically appeared to be the microgranular variant of acute promyelocytic leukemia. This represented 8% of CML patients developing blast crisis from 1984 to 1993. Cytogenetic studies revealed translocation 15;17 in addition to trans...

journal_title：American journal of clinical pathology

authors： Rosenthal NS,Knapp D,Farhi DC

更新日期：1995-02-01 00:00:00

abstract：:We examined benign and malignant mesothelial tissue samples for the presence of X-linked inhibitor of apoptosis protein (XIAP), a potent constituent of the inhibitor of apoptosis family of caspase inhibitors. We subjected 55 sections (31 malignant mesotheliomas, 2 well-differentiated peritoneal mesotheliomas, 13 pleur...

journal_title：American journal of clinical pathology

authors： Wu M,Sun Y,Li G,Desman G,Wang B,Gil J,Burstein DE

更新日期：2007-11-01 00:00:00

abstract：:Human papillomavirus (HPV) testing is more sensitive for the detection of cervical precancer and cancer than cervical cytology. The increased sensitivity of HPV testing and cytology combined ("cotesting") compared to cytology alone permitted professional societies to recommend 3-year screening intervals among the cote...

journal_title：American journal of clinical pathology

authors： Kinney W,Stoler MH,Castle PE

更新日期：2010-08-01 00:00:00

abstract：:Few cases of secondary CD5+ diffuse large B-cell lymphoma (DLBCL) that are not Richter syndrome have been reported previously. We report 9 cases of non-Richter syndrome secondary CD5+ DLBCL. Among 529 cases of DLBCL, 38 (7.2%) were CD5+ DLBCL, including 9 of secondary CD5+ DLBCL. Five cases gained CD5 expression durin...

journal_title：American journal of clinical pathology

authors： Maeshima AM,Taniguchi H,Nomoto J,Maruyama D,Kim SW,Watanabe T,Kobayashi Y,Tobinai K,Matsuno Y

更新日期：2009-03-01 00:00:00

abstract：:The authors investigated the humoral and tissue expression of six antigens associated with medullary thyroid cancer (MTC): calcitonin (CT), calcitonin gene-related peptide (CGRP), carcinoembryonic antigen (CEA), neuron-specific enolase (NSE), somatostatin (SRIF), and thyroglobulin (TG). The antigens were studied in th...

journal_title：American journal of clinical pathology

authors： Pacini F,Basolo F,Elisei R,Fugazzola L,Cola A,Pinchera A

更新日期：1991-03-01 00:00:00

abstract：:B5 fixation achieves superior morphologic detail. However, environmental concerns have led to labor-intensive and costly requirements for disposal of mercury-containing fixatives. We performed a blinded prospective study to find a safe, mercury-free alternative to B5. Morphology was evaluated with 6 fixatives, includi...

journal_title：American journal of clinical pathology

authors： Bonds LA,Barnes P,Foucar K,Sever CE

更新日期：2005-08-01 00:00:00

abstract：:Patients with nonhemolytic Lewis antibodies in the serum were transfused on the basis of major crossmatch compatibility alone. No adverse clinical affects were noted when 33 such patients received a total of 230 transfusions. Considerable savings in technologist time and reagent cost were realized by adopting this pol...

journal_title：American journal of clinical pathology

authors： Waheed A,Kennedy MS,Gerhan S,Senhauser DA

更新日期：1981-09-01 00:00:00

abstract：:We report 2 cases of splenic postchemotherapy histiocyte-rich pseudotumor. Each patient had a history of diffuse large B-cell lymphoma, treated with multiagent chemotherapy. Computed tomography scans performed on both patients showed splenic masses. A positron emission tomography scan performed on 1 patient showed inc...

journal_title：American journal of clinical pathology

authors： Chandra P,Wen YH,Tuli S,Raphael BG,Amorosi EL,Medeiros LJ,Ibrahim S

更新日期：2009-09-01 00:00:00

abstract：:While plasmacytosis is a common occurrence in early post-bone marrow transplantation biopsy specimens, the significance of plasma cells in such specimens from patients with multiple myeloma (MM) is unknown. We attempted to retrospectively determine, by morphologic assessment of plasma cell percentage, immunohistologic...

journal_title：American journal of clinical pathology

authors： Maia DM,Kell DL,Goates JJ,Warnke RA

更新日期：1997-06-01 00:00:00