An approach to immunomicroscopy of renal disease with immunoperoxidase and periodic acid-Schiff counterstain (IMPAS stain).

abstract：:The authors describe two patients with clinically and histopathologically documented advanced (tumor) stage mycosis fungoides. In each case the large, pleomorphic neoplastic cells lacked the monoclonal antibody-defined cell surface antigens commonly associated with immature and mature T-cells, i.e., T11, Leu-1, T3, T4...

journal_title：American journal of clinical pathology

authors： Wieczorek R,Suhrland M,Ramsay D,Reed ML,Knowles DM 2nd

更新日期：1986-07-01 00:00:00

abstract：:To determine the performance and frequency of protein C reagents currently used by clinical laboratories, we analyzed North American Specialized Coagulation Laboratory Association (NASCOLA) protein C proficiency testing data from 6 surveys conducted in 2009 and 2010 (2009-1 to 2009-3 and 2010-1 to 2010-3). Interlabora...

journal_title：American journal of clinical pathology

authors： Baron JM,Johnson SM,Ledford-Kraemer MR,Hayward CP,Meijer P,Van Cott EM

更新日期：2012-06-01 00:00:00

abstract：:Clotting tests based upon the activated partial thromboplastin time are disturbed by heparin. This brief communication shows that Factor XII clotting activity in plasma samples heparinized in vitro and in vivo can be measured accurately by means of an aPTT-test using congenitally deficient substrate plasma when the pl...

journal_title：American journal of clinical pathology

authors： Lämmle B,Tran TH,Duckert F

更新日期：1983-10-01 00:00:00

abstract：:The platelet aggregation responses induced by adenosine diphosphate (ADP) and collagen were characterized by parameters defining rate and extent of reaction. Values were compared on the basis of platelet concentration, time elapsed between sample collection and test performance, and sex of donors. Rate and extent of a...

journal_title：American journal of clinical pathology

authors： Roper P,Drewinko B,Hasler D,Johnston D,Hester J,Freireich EJ

更新日期：1979-03-01 00:00:00

abstract：:We compared a rapid, point-of-care multimarker protocol with a single and serial troponin I (TnI)-only protocol in 5,244 patients admitted to the emergency department with chest pain. The diagnosis of acute myocardial infarction (AMI) was based on a doubling myoglobin level accompanied by at least a 50% increase in th...

journal_title：American journal of clinical pathology

authors： Straface AL,Myers JH,Kirchick HJ,Blick KE

更新日期：2008-05-01 00:00:00

abstract：:We describe a method of spectrophotometric detection of BCR/ABL chimeric sequences amplified by multiplex reverse transcriptase-polymerase chain reaction (RT-PCR), enabling the use of archival hematologic slides as RNA sources. Multiplex PCR amplified b3a2, b2a2, and e1a2 break points of the BCR/ABL translocation and ...

journal_title：American journal of clinical pathology

authors： Attadia V,Alosi M,Improta S,Zagonel V,Martinazzo G,Carbone A,Pinto A

更新日期：1997-10-01 00:00:00

abstract：:Factor V Leiden (FVR506Q) is a genetic defect in the factor V (FV) molecule that confers resistance to proteolysis by activated protein C (APC) and is the most common abnormality detected in patients studied for hereditary thrombophilia. The initial screening test for this abnormality was a comparison of the activated...

journal_title：American journal of clinical pathology

authors： Akhtar MS,Blair AJ,King TC,Sweeney JD

更新日期：1998-04-01 00:00:00

abstract：:Twenty-four cases of a lesion characterized by unlined spaces in the colorectal lamina propria are presented. While lesions such as this have been reported previously as "lipomatosis" of the colon, histochemical and ultrastructural examination reveals that they are not, in fact, composed of adipocytes. It appears that...

journal_title：American journal of clinical pathology

authors： Snover DC,Sandstad J,Hutton S

更新日期：1985-11-01 00:00:00

abstract：:Riedel thyroiditis (RT) is an uncommon form of chronic thyroiditis in which the thyroid gland is replaced by fibrous tissue. The etiologic mechanisms underlying RT are unclear: the prevailing view is that it is part of a generalized fibroinflammatory process also involving other organs. The clinical manifestations of ...

journal_title：American journal of clinical pathology

authors： Papi G,LiVolsi VA

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVES:GATA3 is a transcription factor regulating luminal cell differentiation in the mammary glands and has been implicated in the luminal types of breast carcinoma. The prognostic significance of GATA3 in breast cancer remains controversial. METHODS:In this study, we assessed the prognostic value of the molecule...

journal_title：American journal of clinical pathology

authors： McCleskey BC,Penedo TL,Zhang K,Hameed O,Siegal GP,Wei S

更新日期：2015-11-01 00:00:00

abstract：:Same-day turnaround of pathology specimens is desirable in this era of managed care, and rapid microwave tissue processing produces histologic features of a quality equivalent to overnight processing. We studied whether microwave-assisted rapid tissue processing adversely affects the quality of immunohistochemical sta...

journal_title：American journal of clinical pathology

authors： Emerson LL,Tripp SR,Baird BC,Layfield LJ,Rohr LR

更新日期：2006-02-01 00:00:00

abstract：:We compared 1-stage clot-based, chromogenic, and immunoassay methods for measuring factor VIII in plasma with a focus on the measurement of elevated levels of factor VIII. The chromogenic assay showed the best interassay imprecision for factor VIII levels near 150 IU/dL. The best correlation was between the 1-stage cl...

journal_title：American journal of clinical pathology

authors： Chandler WL,Ferrell C,Lee J,Tun T,Kha H

更新日期：2003-07-01 00:00:00

abstract：:We further characterize the heterogeneous carcinomas of the papilla of Vater (CPVs) in relation to various clinicopathologic patient characteristics and patient survival. Of the 71 reevaluated CPVs, 32 were intestinal, 26 were pancreatobiliary, 6 were mixed, 4 were mucinous, and 3 were poorly differentiated carcinomas...

journal_title：American journal of clinical pathology

authors： Kohler I,Jacob D,Budzies J,Lehmann A,Weichert W,Schulz S,Neuhaus P,Röcken C

更新日期：2011-02-01 00:00:00

abstract：:Recent studies in Western populations have shown that trisomy 3 is the most frequent chromosomal abnormality in primary gastric lymphoma (PGL). To study the incidence of trisomy 3 and its implications for the pathogenesis of PGL in Hong Kong, we have applied the technique of chromosome in situ hybridization in 13 case...

journal_title：American journal of clinical pathology

authors： Zhang Y,Cheung AN,Chan AC,Shen DH,Xu WS,Chung LP,Ho FC

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVES:Preanalytical factors, such as hemolysis, affect many components of a test panel. Machine learning can be used to recognize these patterns, alerting clinicians and laboratories to potentially erroneous results. In particular, machine learning might identify which cases of elevated potassium from a point-of-c...

journal_title：American journal of clinical pathology

authors： Benirschke RC,Gniadek TJ

更新日期：2020-07-07 00:00:00

abstract：:This report concerns a particular benign histologic variant of Hodgkin's disease, the lymphocyte-predominant category of the Rye classification. The group of 24 cases, all involving localized disease, was first reported in 1960, and is now reappraised, incorporating subsequent data. The interpretations of the original...

journal_title：American journal of clinical pathology

authors： Wright CJ

更新日期：1977-06-01 00:00:00

abstract：:To assess the observation that blood type B might be a marker for longevity, we reviewed the records and determined the ABO blood types of all patients who died in our hospital in 2004. Age was stratified by decade of death, and linear regressions were calculated by ABO percentage. ABO survival curves were compared. I...

journal_title：American journal of clinical pathology

authors： Brecher ME,Hay SN

更新日期：2011-01-01 00:00:00

abstract：:Prostate-specific antigen (PSA) is a sensitive and specific serum marker for monitoring disease activity in men with prostatic carcinoma. Despite reports of elevation of levels of this analyte in men with benign prostatic hyperplasia, no information is available correlating the serum levels with the actual prostatic a...

journal_title：American journal of clinical pathology

authors： Brawer MK,Rennels MA,Nagle RB,Schifman R,Gaines JA

更新日期：1989-12-01 00:00:00

abstract：Objectives:To curtail inappropriate plasma transfusions, we instituted clinical decision support as an alert upon order entry if the patient's recent international normalized ratio (INR) was 1.7 or less. Methods:The alert was suppressed for massive transfusion and within operative or apheresis settings. The plasma ord...

journal_title：American journal of clinical pathology

authors： Shah N,Baker SA,Spain D,Shieh L,Shepard J,Hadhazy E,Maggio P,Goodnough LT

更新日期：2017-08-01 00:00:00

abstract：:A man was hospitalized with bacteremic Achromobacter xylosoxidans type IIIa pneumonia. The authors are aware of no previously reported similar infections caused by this bacterium. A clinical cure was achieved with a combination of carbenicillin and kanamycin therapy. Microtiter susceptibility testing revealed that car...

journal_title：American journal of clinical pathology

authors： Dworzack DL,Murray CM,Hodges GR,Barnes WG

更新日期：1978-10-01 00:00:00

abstract：:A patient with an acute burn was noticed to have spuriously elevated platelet counts on an automated system. The major factor accounting for this discrepancy was the presence of numerous microspherocytes which were in the same size range of platelets. It is thus important to add microspherocytosis as an additional cau...

journal_title：American journal of clinical pathology

authors： Akwari AM,Ross DW,Stass SA

更新日期：1982-02-01 00:00:00

abstract：:The authors investigated the humoral and tissue expression of six antigens associated with medullary thyroid cancer (MTC): calcitonin (CT), calcitonin gene-related peptide (CGRP), carcinoembryonic antigen (CEA), neuron-specific enolase (NSE), somatostatin (SRIF), and thyroglobulin (TG). The antigens were studied in th...

journal_title：American journal of clinical pathology

authors： Pacini F,Basolo F,Elisei R,Fugazzola L,Cola A,Pinchera A

更新日期：1991-03-01 00:00:00

abstract：:The combined experience of four university medical centers with fine-needle aspiration biopsy (FNAB) of the mediastinum is reviewed. This series includes 189 cases, with 100 males and 89 females, 6 months to 86 years of age. The majority (71%) of diagnoses were neoplastic with the remainder equally distributed between...

journal_title：American journal of clinical pathology

authors： Powers CN,Silverman JF,Geisinger KR,Frable WJ

更新日期：1996-02-01 00:00:00

abstract：:A flow cytometric technic was developed to detect platelet surface-bound immunoglobulin in patients with thrombocytopenia. Elevated platelet surface IgG and/or IgM was detected in 90.9% of patients with immune thrombocytopenia purpura (ITP). False positive results occurred in 9.3% of patients with nonimmune thrombocyt...

journal_title：American journal of clinical pathology

authors： Rosenfeld CS,Nichols G,Bodensteiner DC

更新日期：1987-04-01 00:00:00

abstract：:Proteomic studies of cells via surface-enhanced laser desorption/ionization spectrometry (SELDI) analysis have enabled rapid, reproducible protein profiling directly from crude samples. We applied this technique to archival cytology material to determine whether distinct, reproducible protein fingerprints could be ide...

journal_title：American journal of clinical pathology

authors： Fetsch PA,Simone NL,Bryant-Greenwood PK,Marincola FM,Filie AC,Petricoin EF,Liotta LA,Abati A

更新日期：2002-12-01 00:00:00

abstract：:Immunohistochemical techniques applied to fresh frozen sections of metastatic malignant melanoma tissue revealed abundant fibrinogen (or fibrin I) in perivascular areas throughout the tumor connective tissue stroma. Fibrin was readily detected in a focal distribution in the connective tissue around nodules of viable t...

journal_title：American journal of clinical pathology

authors： Wojtukiewicz MZ,Zacharski LR,Memoli VA,Kisiel W,Kudryk BJ,Rousseau SM,Stump DC

更新日期：1990-04-01 00:00:00

abstract：:We analyzed the value in cervical cytology of a recently developed technique by which it is possible to remove thick tissue specimens, called microbiopsies, from cervical smears and to process them for histologic examination. In 12 (48%) of 25 cervical smears in which microbiopsies were found, the histologic sections ...

journal_title：American journal of clinical pathology

authors： Mravunac M,Verbeek DH,Sanders-Eras M,Besseling R,Wijnen-Dubbers C,Smedts F

更新日期：1997-08-01 00:00:00

abstract：:The 1973 Comprehensive Blood Bank Survey Program of the College of American Pathologists was administered to 2,200 laboratories and blood banks throughout the United States. The results showed a considerable increase in the accuracy of the testing and in the performance of reagents. Accuracy of ABO testing was 99.3%; ...

journal_title：American journal of clinical pathology

authors： Myhre BA,Koepke JA

更新日期：1975-06-01 00:00:00

abstract：:The results of hepatitis B surface antigen (HBs-Ag) testing in a large volunteer blood donor population are described. Counterelectrophoresis and three versions of solid-phase radioimmunoassay technic are compared and evaluated. Initial results suggested that the radioimmunoassay technic are compared and evaluated. In...

journal_title：American journal of clinical pathology

authors： Dodd RY,Ni LY,Mallin WS,Greenwalt TJ

更新日期：1975-06-01 00:00:00

abstract：:Cytogenetic studies of bone marrow were performed in 230 consecutive cases of patients with chronic granulocytic leukemia (CGL) admitted to the National Cancer Institute since 1961. Twenty patients lacked the Philadelphia (Ph1) chromosome. All were previously untreated. When compared with Ph1-positive patients, CGL pa...

journal_title：American journal of clinical pathology

authors： Canellos GP,Whang-Peng J,DeVita VT

更新日期：1976-04-01 00:00:00